JP2005521429A5 - - Google Patents

Info

Publication number

JP2005521429A5

JP2005521429A5 JP2003586337A JP2003586337A JP2005521429A5 JP 2005521429 A5 JP2005521429 A5 JP 2005521429A5 JP 2003586337 A JP2003586337 A JP 2003586337A JP 2003586337 A JP2003586337 A JP 2003586337A JP 2005521429 A5 JP2005521429 A5 JP 2005521429A5

Authority

JP

Japan

Prior art keywords

seq

fcrh

nucleic acid

amino acid

sequence

Prior art date

2003-03-25

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• 102000039446 nucleic acids Human genes 0.000 claims 90
• 108020004707 nucleic acids Proteins 0.000 claims 90
• 150000007523 nucleic acids Chemical class 0.000 claims 90
• 125000003275 alpha amino acid group Chemical group 0.000 claims 70
• 239000002773 nucleotide Substances 0.000 claims 42
• 125000003729 nucleotide group Chemical group 0.000 claims 42
• 229920001184 polypeptide Polymers 0.000 claims 38
• 102000004196 processed proteins & peptides Human genes 0.000 claims 38
• 108090000765 processed proteins & peptides Proteins 0.000 claims 38
• 238000009396 hybridization Methods 0.000 claims 28
• 239000000523 sample Substances 0.000 claims 28
• 150000001413 amino acids Chemical class 0.000 claims 24
• 239000012634 fragment Substances 0.000 claims 22
• 201000011510 cancer Diseases 0.000 claims 17
• 238000006467 substitution reaction Methods 0.000 claims 15
• 210000004027 cell Anatomy 0.000 claims 14
• 230000000295 complement effect Effects 0.000 claims 14
• 206010028980 Neoplasm Diseases 0.000 claims 12
• 210000003958 hematopoietic stem cell Anatomy 0.000 claims 12
• 230000036210 malignancy Effects 0.000 claims 12
• 230000001086 cytosolic effect Effects 0.000 claims 10
• 238000012258 culturing Methods 0.000 claims 7
• 239000013604 expression vector Substances 0.000 claims 7
• 238000004519 manufacturing process Methods 0.000 claims 7
• 239000013598 vector Substances 0.000 claims 7
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 6
• 208000023275 Autoimmune disease Diseases 0.000 claims 6
• 102000001708 Protein Isoforms Human genes 0.000 claims 5
• 108010029485 Protein Isoforms Proteins 0.000 claims 5
• 210000001744 T-lymphocyte Anatomy 0.000 claims 4
• 239000013068 control sample Substances 0.000 claims 4
• 230000001900 immune effect Effects 0.000 claims 4
• 210000003719 b-lymphocyte Anatomy 0.000 claims 3
• 230000028996 humoral immune response Effects 0.000 claims 3
• 102000005962 receptors Human genes 0.000 claims 3
• 108020003175 receptors Proteins 0.000 claims 3
• 230000002378 acidificating effect Effects 0.000 claims 2
• 238000000034 method Methods 0.000 claims 2
• 102100031517 Fc receptor-like protein 1 Human genes 0.000 claims 1
• 101710120224 Fc receptor-like protein 1 Proteins 0.000 claims 1
• 102100031511 Fc receptor-like protein 2 Human genes 0.000 claims 1
• 101000846911 Homo sapiens Fc receptor-like protein 2 Proteins 0.000 claims 1
• WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
• 230000004988 N-glycosylation Effects 0.000 claims 1
• 201000010099 disease Diseases 0.000 claims 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
• 229930195712 glutamate Natural products 0.000 claims 1
• 210000000066 myeloid cell Anatomy 0.000 claims 1
• 230000002285 radioactive effect Effects 0.000 claims 1
• 239000003053 toxin Substances 0.000 claims 1
• 231100000765 toxin Toxicity 0.000 claims 1