JP4145314B2 - 腫瘍細胞成長阻害のための組成物及び方法 - Google Patents

腫瘍細胞成長阻害のための組成物及び方法 Download PDF

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Publication number
JP4145314B2
JP4145314B2 JP2005229454A JP2005229454A JP4145314B2 JP 4145314 B2 JP4145314 B2 JP 4145314B2 JP 2005229454 A JP2005229454 A JP 2005229454A JP 2005229454 A JP2005229454 A JP 2005229454A JP 4145314 B2 JP4145314 B2 JP 4145314B2
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Japan
Prior art keywords
amino acid
sequence
polypeptide
acid sequence
antibody
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Expired - Lifetime
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JP2005229454A
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English (en)
Japanese (ja)
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JP2006025793A5 (enExample
JP2006025793A (ja
Inventor
ベーカー，ケヴィン，ピー．
ゴッダード，オードリー
ガーニー，オースティン，エル．
ヘベール，キャロライン
ヘンゼル，ウィリアム
カバコフ，ローナ，シー．
シェルトン，デイビッド，エル．
スミス，ヴィクトリア
ワタナベ，コリン，ケー．
ウッド，ウィリアム，アイ．
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Genentech Inc
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Genentech Inc
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Publication date
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/en
Priority claimed from PCT/US1999/020111 external-priority patent/WO2000012708A2/en
Priority claimed from PCT/US1999/020594 external-priority patent/WO2000015666A2/en
Priority claimed from PCT/US1999/028313 external-priority patent/WO2000032221A2/en
Priority claimed from PCT/US1999/028634 external-priority patent/WO2000036102A2/en
Priority claimed from PCT/US1999/028551 external-priority patent/WO2000053750A1/en
Priority claimed from PCT/US1999/030095 external-priority patent/WO2000037640A2/en
Priority claimed from PCT/US1999/030999 external-priority patent/WO2001005836A1/en
Priority claimed from PCT/US2000/000376 external-priority patent/WO2000053755A2/en
Priority claimed from PCT/US2000/003565 external-priority patent/WO2001053486A1/en
Priority claimed from PCT/US2000/004342 external-priority patent/WO2000078961A1/en
Priority claimed from PCT/US2000/004341 external-priority patent/WO2000053756A2/en
Priority claimed from PCT/US2000/005841 external-priority patent/WO2000053758A2/en
Priority claimed from PCT/US2000/006319 external-priority patent/WO2000053760A2/en
Priority claimed from PCT/US2000/006884 external-priority patent/WO2001005972A1/en
Priority claimed from PCT/US2000/008439 external-priority patent/WO2000073454A1/en
Priority claimed from PCT/US2000/013705 external-priority patent/WO2000073445A2/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JP2006025793A publication Critical patent/JP2006025793A/ja
Publication of JP2006025793A5 publication Critical patent/JP2006025793A5/ja
Application granted granted Critical
Publication of JP4145314B2 publication Critical patent/JP4145314B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2005229454A 1999-06-02 2005-08-08 腫瘍細胞成長阻害のための組成物及び方法 Expired - Lifetime JP4145314B2 (ja)

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
PCT/US1999/012252 WO1999063088A2 (en) 1998-06-02 1999-06-02 Membrane-bound proteins and nucleic acids encoding the same
US14065099P 1999-06-22 1999-06-22
US14103799P 1999-06-23 1999-06-23
US14475899P 1999-07-20 1999-07-20
PCT/US1999/020111 WO2000012708A2 (en) 1998-09-01 1999-09-01 Further pro polypeptides and sequences thereof
PCT/US1999/020594 WO2000015666A2 (en) 1998-09-10 1999-09-08 Compositions and methods for the treatment of tumors
US16250699P 1999-10-29 1999-10-29
PCT/US1999/028313 WO2000032221A2 (en) 1998-12-01 1999-11-30 Promotion or inhibition of angiogenesis and cardiovascularization
PCT/US1999/028634 WO2000036102A2 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US1999/028551 WO2000053750A1 (en) 1999-03-08 1999-12-02 Compositions and methods for the treatment of tumors
US17026299P 1999-12-09 1999-12-09
PCT/US1999/030095 WO2000037640A2 (en) 1998-12-22 1999-12-16 Compositions and methods for the treatment of tumor
PCT/US1999/030999 WO2001005836A1 (en) 1999-07-20 1999-12-20 Polypeptidic compositions and methods for the treatment of tumors
PCT/US2000/000376 WO2000053755A2 (en) 1999-03-08 2000-01-06 Compositions and methods for the treatment of tumor
PCT/US2000/003565 WO2001053486A1 (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumor
PCT/US2000/004342 WO2000078961A1 (en) 1999-06-23 2000-02-18 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2000/004341 WO2000053756A2 (en) 1999-03-08 2000-02-18 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2000/005841 WO2000053758A2 (en) 1999-03-08 2000-03-02 Compositions and methods for the treatment of immune related diseases
US18720200P 2000-03-03 2000-03-03
PCT/US2000/006319 WO2000053760A2 (en) 1999-03-12 2000-03-10 Method of preventing the death of retinal neurons and treating ocular diseases
PCT/US2000/006884 WO2001005972A1 (en) 1999-07-20 2000-03-15 Compositions and methods for the treatment of immune related diseases
PCT/US2000/008439 WO2000073454A1 (en) 1999-06-02 2000-03-30 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2000/013705 WO2000073445A2 (en) 1999-06-02 2000-05-17 Interleukin-1-receptor associated kinase-3 (irak3)

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2001500672A Division JP2003524406A (ja) 1999-06-02 2000-05-30 腫瘍細胞成長阻害のための組成物及び方法

Related Child Applications (3)

Application Number Title Priority Date Filing Date
JP2006225770A Division JP4072181B2 (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法
JP2006225772A Division JP2007029098A (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法
JP2006225771A Division JP4074645B2 (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法

Publications (3)

Publication Number Publication Date
JP2006025793A JP2006025793A (ja) 2006-02-02
JP2006025793A5 JP2006025793A5 (enExample) 2007-07-12
JP4145314B2 true JP4145314B2 (ja) 2008-09-03

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2005229454A Expired - Lifetime JP4145314B2 (ja) 1999-06-02 2005-08-08 腫瘍細胞成長阻害のための組成物及び方法
JP2006225770A Expired - Lifetime JP4072181B2 (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法
JP2006225772A Pending JP2007029098A (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法
JP2006225771A Expired - Lifetime JP4074645B2 (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2006225770A Expired - Lifetime JP4072181B2 (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法
JP2006225772A Pending JP2007029098A (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法
JP2006225771A Expired - Lifetime JP4074645B2 (ja) 1999-06-02 2006-08-22 腫瘍細胞成長阻害のための組成物及び方法

Country Status (8)

Country Link
EP (1) EP1185648B1 (enExample)
JP (4) JP4145314B2 (enExample)
AT (1) ATE357518T1 (enExample)
CA (1) CA2373915A1 (enExample)
DK (1) DK1185648T3 (enExample)
ES (1) ES2287020T3 (enExample)
PT (1) PT1185648E (enExample)
WO (1) WO2000073348A2 (enExample)

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US7282562B2 (en) 1999-08-31 2007-10-16 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2001023553A2 (en) * 1999-09-29 2001-04-05 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Metastasis-associated antigen c4.4a
EP1242598A2 (en) * 1999-12-30 2002-09-25 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
AU2001255168A1 (en) * 2000-03-03 2001-09-17 Genentech Inc. Compositions and methods for the treatment of immune related diseases
WO2001072958A2 (en) * 2000-03-28 2001-10-04 Beth Israel Deaconess Medical Center Bladder cancer-specific peptides for diagnosis and therapy
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US7276580B2 (en) 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
US6734289B2 (en) 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
US7629317B2 (en) 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
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AU2003267096B9 (en) * 2002-09-11 2010-11-11 Genentech, Inc. Novel compositions and methods for the treatment of immune related diseases
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US20050187175A1 (en) * 2003-09-30 2005-08-25 Elly Nedivi Methods and compositions for CPG15-2
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ATE472333T1 (de) 2004-08-19 2010-07-15 Biogen Idec Inc Rückfaltung von proteinen der transforming-growth-factor-beta-familie
US8017576B2 (en) 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis
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WO2007095113A2 (en) 2006-02-10 2007-08-23 Massachusetts Institute Of Technology Cpg15 and cpg15-2 compounds and inhibitors as insulin receptor and insulin-like growth factor receptor agonists and antagonists
TWI501774B (zh) 2006-02-27 2015-10-01 Biogen Idec Inc 神經性病症之治療
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HRP20231525T1 (hr) 2009-02-20 2024-03-15 Astellas Pharma Inc. Postupci i pripravci za dijagnozu i liječenje raka
HUE035516T2 (en) 2009-11-11 2018-05-28 Ganymed Pharmaceuticals Gmbh Antibodies specific to Claulin-6 (CLDN6)
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Publication number Publication date
PT1185648E (pt) 2007-06-29
CA2373915A1 (en) 2000-12-07
JP2006025793A (ja) 2006-02-02
ES2287020T3 (es) 2007-12-16
JP4074645B2 (ja) 2008-04-09
EP1185648A2 (en) 2002-03-13
JP2007014346A (ja) 2007-01-25
DK1185648T3 (da) 2007-07-30
WO2000073348A2 (en) 2000-12-07
JP2007029098A (ja) 2007-02-08
JP4072181B2 (ja) 2008-04-09
WO2000073348A3 (en) 2001-07-05
ATE357518T1 (de) 2007-04-15
EP1185648B1 (en) 2007-03-21
JP2007029097A (ja) 2007-02-08

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