|
US4415732A
(en)
*
|
1981-03-27 |
1983-11-15 |
University Patents, Inc. |
Phosphoramidite compounds and processes
|
|
DE3239887A1
(de)
|
1982-10-28 |
1984-05-03 |
Hubert Prof. Dr. 2000 Hamburg Köster |
Verfahren zur herstellung von oligonucleotiden
|
|
US5198540A
(en)
*
|
1982-10-28 |
1993-03-30 |
Hubert Koster |
Process for the preparation of oligonucleotides in solution
|
|
DE3239888A1
(de)
|
1982-10-28 |
1984-05-03 |
Hubert Prof. Dr. 2000 Hamburg Köster |
Verfahren zur herstellung von oligonucleosidphosphonaten
|
|
DE3326520A1
(de)
|
1983-07-22 |
1985-01-31 |
Hubert Prof. Dr. 2000 Hamburg Köster |
Verfahren zur definierten verknuepfung doppelhelikaler dna-fragmente mittels einer linker-dna sowie als linker-dna geeignete oligonucletide
|
|
DE3329892A1
(de)
|
1983-08-18 |
1985-03-07 |
Köster, Hubert, Prof. Dr., 2000 Hamburg |
Verfahren zur herstellung von oligonucleotiden
|
|
DE3546891C2
(de)
*
|
1985-10-21 |
2000-06-08 |
Papst Licensing Gmbh & Co Kg |
Treiberschaltung zum Betrieb eines kollektorlosen Gleichstrommotors in einem Lüfter oder zum Antrieb eines Lüfters
|
|
EP0285675A1
(de)
|
1987-02-06 |
1988-10-12 |
BIOSYNTECH Biochemische Synthesetechnik GmbH |
Synthetische DNA-Kassetten mit Kodierung fuer artifizielle Proteine und deren Expression
|
|
US4923901A
(en)
|
1987-09-04 |
1990-05-08 |
Millipore Corporation |
Membranes with bound oligonucleotides and peptides
|
|
EP0310361A3
(en)
|
1987-09-30 |
1989-05-24 |
Beckman Instruments, Inc. |
Tridentate conjugate and method of use thereof
|
|
JPS6455181U
(enExample)
|
1987-09-30 |
1989-04-05 |
|
|
|
US5770625A
(en)
|
1988-02-08 |
1998-06-23 |
The Trustees Of Columbia University In The City Of New York |
Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
|
|
US5011861A
(en)
|
1988-06-28 |
1991-04-30 |
Millipore Corporation |
Membranes for solid phase protein sequencing
|
|
US5143854A
(en)
*
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US5547839A
(en)
*
|
1989-06-07 |
1996-08-20 |
Affymax Technologies N.V. |
Sequencing of surface immobilized polymers utilizing microflourescence detection
|
|
WO1991004258A1
(fr)
*
|
1989-09-22 |
1991-04-04 |
Mitsui Toatsu Chemicals, Incorporated |
Derive d'ionisotol et production de ce derive
|
|
US5410068A
(en)
*
|
1989-10-23 |
1995-04-25 |
Perseptive Biosystems, Inc. |
Succinimidyl trityl compounds and a process for preparing same
|
|
US5723286A
(en)
*
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
|
DK0550592T3
(da)
*
|
1990-09-24 |
1997-07-07 |
Roger Brent |
Screeningsanalyser.
|
|
DE69333366T2
(de)
*
|
1992-10-30 |
2004-09-16 |
The General Hospital Corp., Boston |
Ein neues zellzyklus kontrollprotein
|
|
US6436635B1
(en)
*
|
1992-11-06 |
2002-08-20 |
Boston University |
Solid phase sequencing of double-stranded nucleic acids
|
|
DE69433811T2
(de)
|
1993-01-07 |
2005-06-23 |
Sequenom, Inc., San Diego |
Dns - sequenzierung durch massenspektronomie
|
|
US6194144B1
(en)
*
|
1993-01-07 |
2001-02-27 |
Sequenom, Inc. |
DNA sequencing by mass spectrometry
|
|
US5605798A
(en)
*
|
1993-01-07 |
1997-02-25 |
Sequenom, Inc. |
DNA diagnostic based on mass spectrometry
|
|
US5512473A
(en)
*
|
1993-01-29 |
1996-04-30 |
Brent; Roger |
Max-interacting proteins and related molecules and methods
|
|
US6074823A
(en)
*
|
1993-03-19 |
2000-06-13 |
Sequenom, Inc. |
DNA sequencing by mass spectrometry via exonuclease degradation
|
|
DE69430909T2
(de)
*
|
1993-03-19 |
2003-02-27 |
Sequenom, Inc. |
Dns-sequenzbestimmung durch massenspektrometrie auf dem weg des abbaus mit exonuklease
|
|
CA2162568C
(en)
|
1993-05-10 |
2001-10-30 |
Yuichi Oku |
Method and reagent for simultaneously assaying one or more ligands in a group of preselected ligands
|
|
US5695941A
(en)
*
|
1994-06-22 |
1997-12-09 |
The General Hospital Corporation |
Interaction trap systems for analysis of protein networks
|
|
US6428955B1
(en)
*
|
1995-03-17 |
2002-08-06 |
Sequenom, Inc. |
DNA diagnostics based on mass spectrometry
|
|
CA2217545A1
(en)
*
|
1995-04-11 |
1996-10-17 |
Marc Vidal |
Reverse two-hybrid systems
|
|
EP0830460A1
(en)
|
1995-04-11 |
1998-03-25 |
Trustees Of Boston University |
Solid phase sequencing of biopolymers
|
|
US6017496A
(en)
*
|
1995-06-07 |
2000-01-25 |
Irori |
Matrices with memories and uses thereof
|
|
US5961923A
(en)
*
|
1995-04-25 |
1999-10-05 |
Irori |
Matrices with memories and uses thereof
|
|
US5925562A
(en)
*
|
1995-04-25 |
1999-07-20 |
Irori |
Remotely programmable matrices with memories
|
|
US5874214A
(en)
*
|
1995-04-25 |
1999-02-23 |
Irori |
Remotely programmable matrices with memories
|
|
US6025129A
(en)
*
|
1995-04-25 |
2000-02-15 |
Irori |
Remotely programmable matrices with memories and uses thereof
|
|
US5741462A
(en)
*
|
1995-04-25 |
1998-04-21 |
Irori |
Remotely programmable matrices with memories
|
|
US5751629A
(en)
*
|
1995-04-25 |
1998-05-12 |
Irori |
Remotely programmable matrices with memories
|
|
US5532379A
(en)
*
|
1995-05-05 |
1996-07-02 |
Pierce Chemical Company |
Biotin containing heterobifunctional cleavable compounds
|
|
US5625184A
(en)
*
|
1995-05-19 |
1997-04-29 |
Perseptive Biosystems, Inc. |
Time-of-flight mass spectrometry analysis of biomolecules
|
|
US5777888A
(en)
*
|
1995-08-09 |
1998-07-07 |
Regents Of The University Of California |
Systems for generating and analyzing stimulus-response output signal matrices
|
|
US5807525A
(en)
*
|
1995-08-17 |
1998-09-15 |
Hybridon, Inc. |
Apparatus and process for multi stage solid phase synthesis of long chained organic molecules
|
|
AU6456496A
(en)
|
1995-08-17 |
1997-03-12 |
Hybridon, Inc. |
Apparatus and process for multi-stage solid-phase synthesis of long-chained organic molecules
|
|
US6146854A
(en)
|
1995-08-31 |
2000-11-14 |
Sequenom, Inc. |
Filtration processes, kits and devices for isolating plasmids
|
|
US5654545A
(en)
*
|
1995-09-19 |
1997-08-05 |
Bruker-Franzen Analytik Gmbh |
Mass resolution in time-of-flight mass spectrometers with reflectors
|
|
US5641959A
(en)
*
|
1995-12-21 |
1997-06-24 |
Bruker-Franzen Analytik Gmbh |
Method for improved mass resolution with a TOF-LD source
|
|
US5742049A
(en)
*
|
1995-12-21 |
1998-04-21 |
Bruker-Franzen Analytik Gmbh |
Method of improving mass resolution in time-of-flight mass spectrometry
|
|
EP1025437A4
(en)
|
1996-03-08 |
2002-10-23 |
Smithkline Beecham Corp |
METHOD FOR DETERMINING THE AFFINITY OF PROTEINS FOR CHEMICAL COMPOUNDS IN SCREENING COMBINATIVE LIBRARIES
|
|
AU2217597A
(en)
|
1996-03-18 |
1997-10-22 |
Sequenom, Inc. |
Dna sequencing by mass spectrometry
|
|
ATE258904T1
(de)
|
1996-04-08 |
2004-02-15 |
Glaxo Group Ltd |
Auf masse basierte kodierung und qualitative analyse von kombinatorischen bibliotheken
|
|
ES2288760T3
(es)
|
1996-04-25 |
2008-01-16 |
Bioarray Solutions Ltd. |
Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
|
|
GB9609262D0
(en)
|
1996-05-02 |
1996-07-03 |
Isis Innovation |
Peptide library and method
|
|
US5777325A
(en)
*
|
1996-05-06 |
1998-07-07 |
Hewlett-Packard Company |
Device for time lag focusing time-of-flight mass spectrometry
|
|
US5928906A
(en)
*
|
1996-05-09 |
1999-07-27 |
Sequenom, Inc. |
Process for direct sequencing during template amplification
|
|
US6022688A
(en)
*
|
1996-05-13 |
2000-02-08 |
Sequenom, Inc. |
Method for dissociating biotin complexes
|
|
NZ333346A
(en)
*
|
1996-06-28 |
2000-03-27 |
Caliper Techn Corp |
High-throughput screening assay systems in microscale fluidic devices
|
|
IL119029A0
(en)
*
|
1996-08-07 |
1996-11-14 |
Yeda Res & Dev |
Long-acting drugs and pharamaceutical compositions comprising them
|
|
US6117631A
(en)
*
|
1996-10-29 |
2000-09-12 |
Polyprobe, Inc. |
Detection of antigens via oligonucleotide antibody conjugates
|
|
DE69727489T2
(de)
*
|
1996-11-06 |
2004-11-25 |
Sequenom, Inc., San Diego |
Verfahren zur massenspektrometrie
|
|
US6140053A
(en)
*
|
1996-11-06 |
2000-10-31 |
Sequenom, Inc. |
DNA sequencing by mass spectrometry via exonuclease degradation
|
|
US6024925A
(en)
*
|
1997-01-23 |
2000-02-15 |
Sequenom, Inc. |
Systems and methods for preparing low volume analyte array elements
|
|
CA2270132A1
(en)
*
|
1996-11-06 |
1998-05-14 |
Sequenom, Inc. |
Dna diagnostics based on mass spectrometry
|
|
US5900481A
(en)
*
|
1996-11-06 |
1999-05-04 |
Sequenom, Inc. |
Bead linkers for immobilizing nucleic acids to solid supports
|
|
DE19782097T1
(de)
|
1996-11-06 |
1999-10-14 |
Sequenom Inc |
Zusammensetzungen und Verfahren zur Immobilisierung von Nucleinsäuren an feste Träger
|
|
US6133436A
(en)
*
|
1996-11-06 |
2000-10-17 |
Sequenom, Inc. |
Beads bound to a solid support and to nucleic acids
|
|
US5812272A
(en)
|
1997-01-30 |
1998-09-22 |
Hewlett-Packard Company |
Apparatus and method with tiled light source array for integrated assay sensing
|
|
DE19882066T1
(de)
*
|
1997-02-04 |
2000-01-05 |
Hubert Koester |
Reversibles stöchiometrisches Verfahren zum Konjugieren von Biomolekülen
|
|
JP2002507197A
(ja)
*
|
1997-05-30 |
2002-03-05 |
ビーエーエスエフ アクチェンゲゼルシャフト |
置換チオピリジン
|
|
NZ516848A
(en)
|
1997-06-20 |
2004-03-26 |
Ciphergen Biosystems Inc |
Retentate chromatography apparatus with applications in biology and medicine
|
|
WO1999002733A1
(en)
*
|
1997-07-07 |
1999-01-21 |
Florida State University |
Identification of molecular targets
|
|
WO1999005320A1
(en)
|
1997-07-22 |
1999-02-04 |
Rapigene, Inc. |
Multiple functionalities within an array element and uses thereof
|
|
US5972639A
(en)
*
|
1997-07-24 |
1999-10-26 |
Irori |
Fluorescence-based assays for measuring cell proliferation
|
|
GB9718129D0
(en)
*
|
1997-08-27 |
1997-10-29 |
Isis Innovation |
Branched structures
|
|
US6207370B1
(en)
*
|
1997-09-02 |
2001-03-27 |
Sequenom, Inc. |
Diagnostics based on mass spectrometric detection of translated target polypeptides
|
|
JP3232052B2
(ja)
*
|
1997-10-31 |
2001-11-26 |
松下電器産業株式会社 |
画像復号化方法
|
|
US5922617A
(en)
|
1997-11-12 |
1999-07-13 |
Functional Genetics, Inc. |
Rapid screening assay methods and devices
|
|
US6268131B1
(en)
*
|
1997-12-15 |
2001-07-31 |
Sequenom, Inc. |
Mass spectrometric methods for sequencing nucleic acids
|
|
US6083682A
(en)
*
|
1997-12-19 |
2000-07-04 |
Glaxo Group Limited |
System and method for solid-phase parallel synthesis of a combinatorial collection of compounds
|
|
AU2100499A
(en)
|
1997-12-19 |
1999-07-12 |
Genetrace Systems, Inc. |
Non-bacterial cloning in delivery and expression of nucleic acids
|
|
CA2323638A1
(en)
|
1998-04-03 |
1999-10-14 |
Phylos, Inc. |
Addressable protein arrays
|
|
US7094943B2
(en)
|
1998-04-27 |
2006-08-22 |
Hubert Köster |
Solution phase biopolymer synthesis
|
|
US6723564B2
(en)
|
1998-05-07 |
2004-04-20 |
Sequenom, Inc. |
IR MALDI mass spectrometry of nucleic acids using liquid matrices
|
|
US6780981B1
(en)
*
|
1998-05-15 |
2004-08-24 |
Oxford Gene Technology Ip Limited |
Libraries of oligomers labeled with different tags
|
|
US6406921B1
(en)
|
1998-07-14 |
2002-06-18 |
Zyomyx, Incorporated |
Protein arrays for high-throughput screening
|
|
ATE253126T1
(de)
|
1998-08-25 |
2003-11-15 |
Univ Washington |
Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
|
|
US6225061B1
(en)
*
|
1999-03-10 |
2001-05-01 |
Sequenom, Inc. |
Systems and methods for performing reactions in an unsealed environment
|
|
US6629040B1
(en)
|
1999-03-19 |
2003-09-30 |
University Of Washington |
Isotope distribution encoded tags for protein identification
|
|
US20020009394A1
(en)
|
1999-04-02 |
2002-01-24 |
Hubert Koster |
Automated process line
|
|
US6391649B1
(en)
|
1999-05-04 |
2002-05-21 |
The Rockefeller University |
Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy
|
|
JP2003508078A
(ja)
*
|
1999-09-03 |
2003-03-04 |
イエール ユニバーシティー |
低分子プローブを使用して遺伝子機能を同定する方法
|
|
WO2001018627A2
(en)
*
|
1999-09-06 |
2001-03-15 |
National University Of Singapore |
Method and apparatus for computer automated detection of protein and nucleic acid targets of a chemical compound
|
|
ATE444532T1
(de)
|
1999-10-13 |
2009-10-15 |
Sequenom Inc |
Verfahren zur identifizierung von polymorphen genetischen markern
|
|
EP1138781A3
(en)
|
2000-03-31 |
2004-07-14 |
Health Research, Inc. |
Method for Quantifying DNA binding activity of DNA binding proteins
|
|
JP2003530365A
(ja)
*
|
2000-04-10 |
2003-10-14 |
ザ スクリプス リサーチ インスティチュート |
プロテオミック分析
|
|
WO2001079562A1
(en)
*
|
2000-04-18 |
2001-10-25 |
Gilead Sciences, Inc. |
Aptamer based two-site binding assay
|
|
US6680178B2
(en)
*
|
2000-06-02 |
2004-01-20 |
The Regents Of The University Of California |
Profiling of protease specificity using combinatorial fluorogenic substrate libraries
|
|
ATE423221T1
(de)
|
2000-06-13 |
2009-03-15 |
Univ Boston |
Verwendung von mass-matched nukleotide in der analyse von oligonukleotidmischungen sowie in der hoch-multiplexen nukleinsäuresequenzierung
|
|
WO2002014856A2
(en)
*
|
2000-08-14 |
2002-02-21 |
Isis Innovation Limited |
Mass spectrometry
|
|
US6531297B2
(en)
|
2000-10-20 |
2003-03-11 |
Applera Corporation |
Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
|
|
JP2004534519A
(ja)
*
|
2000-11-17 |
2004-11-18 |
アルフレッド イー. スランツ |
標的分子機能の決定と薬物リード化合物の同定に関する方法
|
|
US6797523B2
(en)
*
|
2000-11-30 |
2004-09-28 |
Affinium Pharmaceuticals, Inc. |
Methods for systematic identification of protein—protein interactions
|
|
WO2002048403A2
(en)
|
2000-12-11 |
2002-06-20 |
Hk Pharmaceuticals, Inc. |
Multiplexed protein expression and activity assay
|
|
US6887667B2
(en)
|
2000-12-28 |
2005-05-03 |
Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California |
Method and apparatus to identify small variations of biomolecules
|
|
AU2002247097A1
(en)
*
|
2001-02-05 |
2002-08-19 |
Activx Biosciences, Inc. |
Activity based probe analysis
|
|
US7179655B2
(en)
*
|
2001-03-02 |
2007-02-20 |
Activx Biosciences, Inc. |
Protein profiling platform
|
|
EP1383920B1
(en)
|
2001-04-03 |
2010-09-29 |
Thermo Finnigan Llc |
Methods and kits useful for the simplification of complex peptide mixtures
|
|
US20020146684A1
(en)
*
|
2001-04-09 |
2002-10-10 |
Meldal Morten Peter |
One dimensional unichemo protection (UCP) in organic synthesis
|
|
US7045296B2
(en)
|
2001-05-08 |
2006-05-16 |
Applera Corporation |
Process for analyzing protein samples
|
|
US7183116B2
(en)
|
2001-05-14 |
2007-02-27 |
The Institute For Systems Biology |
Methods for isolation and labeling of sample molecules
|
|
GB0116143D0
(en)
|
2001-07-02 |
2001-08-22 |
Amersham Pharm Biotech Uk Ltd |
Chemical capture reagent
|
|
CA2652991A1
(en)
*
|
2001-07-16 |
2003-11-13 |
Caprotec Bioanalytics Gmbh |
Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
|
|
EP1319954A1
(en)
|
2001-12-12 |
2003-06-18 |
Centre National de Genotypage |
Methods for protein analysis using protein capture arrays
|
|
WO2003064704A1
(en)
*
|
2002-01-28 |
2003-08-07 |
Mds Proteomics, Inc. |
Chemical proteomics
|
|
US20030166007A1
(en)
*
|
2002-01-28 |
2003-09-04 |
Mds Proteomics Inc. |
Chemical proteomics
|
|
WO2003077851A2
(en)
|
2002-03-11 |
2003-09-25 |
Hk Pharmaceuticals, Inc. |
Compounds and methods for analyzing the proteome
|
|
AU2003249692B2
(en)
|
2002-06-03 |
2008-07-31 |
The Institute For Systems Biology |
Methods for quantitative proteome analysis of glycoproteins
|
|
WO2003102220A2
(en)
|
2002-06-04 |
2003-12-11 |
The Institute For Systems Biology |
Methods for high throughput and quantitative proteome analysis
|
|
HUP0202212A2
(hu)
*
|
2002-07-10 |
2004-04-28 |
Comgenex Rt. |
Új kombinatorikus fehérjemarker molekulakönyvtárak, eljárás azok előállítására és alkalmazására
|
|
US7473535B2
(en)
|
2002-08-20 |
2009-01-06 |
The Institute For Systems Biology |
Chemical reagents and methods for detection and quantification of proteins in complex mixtures
|
|
US7135288B2
(en)
*
|
2002-09-27 |
2006-11-14 |
Ut-Battelle, Llc |
Combinatorial synthesis of ceramic materials
|
|
WO2004064972A2
(en)
*
|
2003-01-16 |
2004-08-05 |
Hk Pharmaceuticals, Inc. |
Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
|
|
ES2379368T3
(es)
*
|
2004-05-21 |
2012-04-25 |
The Regents Of The University Of California |
Método para aumentar la producción de compuestos isoprenoides
|
|
AU2006259224B2
(en)
|
2005-06-16 |
2012-08-23 |
Mohammed Saeed |
Composition and method for inhibiting, preventing, or ameliorating complications associated with ingestion of a medicinal, chemical, or biological substance or agent
|