EP1025437A4 - A method for determining the affinity of proteins for chemical agents during screening of combinatorial libraries - Google Patents
A method for determining the affinity of proteins for chemical agents during screening of combinatorial librariesInfo
- Publication number
- EP1025437A4 EP1025437A4 EP97908953A EP97908953A EP1025437A4 EP 1025437 A4 EP1025437 A4 EP 1025437A4 EP 97908953 A EP97908953 A EP 97908953A EP 97908953 A EP97908953 A EP 97908953A EP 1025437 A4 EP1025437 A4 EP 1025437A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- affinity
- proteins
- determining
- chemical agents
- combinatorial libraries
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00513—Essentially linear supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
- B01J2219/00536—Sheets in the shape of disks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1313696P | 1996-03-08 | 1996-03-08 | |
US13136P | 1996-03-08 | ||
PCT/US1997/003625 WO1997033169A1 (en) | 1996-03-08 | 1997-03-07 | A method for determining the affinity of proteins for chemical agents during screening of combinatorial libraries |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1025437A1 EP1025437A1 (en) | 2000-08-09 |
EP1025437A4 true EP1025437A4 (en) | 2002-10-23 |
Family
ID=21758497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97908953A Withdrawn EP1025437A4 (en) | 1996-03-08 | 1997-03-07 | A method for determining the affinity of proteins for chemical agents during screening of combinatorial libraries |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1025437A4 (en) |
JP (1) | JP2000508624A (en) |
WO (1) | WO1997033169A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002245988A1 (en) | 2001-04-18 | 2002-10-28 | Ulrich J. Krull | Gradient resolved hybridisation platform |
US7291456B2 (en) | 2002-01-24 | 2007-11-06 | The Regents Of The University Of California | Method for determining differences in molecular interactions and for screening a combinatorial library |
DE60325847D1 (en) * | 2002-03-11 | 2009-03-05 | Caprotec Bioanalytics Gmbh | COMPOUNDS AND PROCEDURES FOR THE ANALYSIS OF THE PROTEOM |
US7635564B2 (en) * | 2002-10-25 | 2009-12-22 | Agilent Technologies, Inc. | Biopolymeric arrays having replicate elements |
EP2259068B1 (en) | 2003-01-16 | 2013-08-14 | caprotec bioanalytics GmbH | Capture compounds and methods for analyzing the proteome |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5591646A (en) * | 1992-09-02 | 1997-01-07 | Arris Pharmaceutical | Method and apparatus for peptide synthesis and screening |
US5288514A (en) * | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
US5834318A (en) * | 1995-05-10 | 1998-11-10 | Bayer Corporation | Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinity purification of target proteins |
-
1997
- 1997-03-07 WO PCT/US1997/003625 patent/WO1997033169A1/en not_active Application Discontinuation
- 1997-03-07 JP JP9531978A patent/JP2000508624A/en active Pending
- 1997-03-07 EP EP97908953A patent/EP1025437A4/en not_active Withdrawn
Non-Patent Citations (3)
Title |
---|
PEASE A C ET AL: "LIGHT-GENERATED OLIGONUCLEOTIDE ARRAYS FOR RAPID DNA SEQUENCE ANALYSIS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 91, 1 May 1994 (1994-05-01), pages 5022 - 5026, XP000196311, ISSN: 0027-8424 * |
See also references of WO9733169A1 * |
SOUTHERN E M ET AL: "ARRAYS OF COMPLEMENTARY OLIGONUCLEOTIDES FOR ANALYSING THE HYBRIDISATION BEHAVIOUR OF NUCLEIC ACIDS", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 22, no. 8, 25 April 1994 (1994-04-25), pages 1368 - 1373, XP000601417, ISSN: 0305-1048 * |
Also Published As
Publication number | Publication date |
---|---|
JP2000508624A (en) | 2000-07-11 |
WO1997033169A1 (en) | 1997-09-12 |
EP1025437A1 (en) | 2000-08-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0914349A4 (en) | Multi-reactor synthesizer and method for combinatorial chemistry | |
EP0900285A4 (en) | Technique for representing combinatorial chemistry libraries resulting from selective combination of synthons | |
AU6695098A (en) | Apparatus and method for combinatorial chemistry synthesis | |
GB2315329B (en) | Method for loading sample supports for mass spectrometers | |
HUP9901560A3 (en) | Mass-based encoding and qualitative analysis of combinatorial libraries | |
EP1007966A4 (en) | Rapid process for arraying and synthesizing bead-based combinatorial libraries | |
GB9608947D0 (en) | Method for determining parameters of hydrocarbon | |
GB9517366D0 (en) | Method of quantatively determining one or more characteristics of a substance | |
GB2325835B (en) | Volumetric pre-clipping method that guarantees minimal number of sample points through a volume | |
EP1015479A4 (en) | Combinatorial libraries of peptidomimetic macrocycles and processes therefor | |
PL348157A1 (en) | Method and apparatus for screening catalyst libraries | |
AU9383198A (en) | Amine compounds and combinatorial libraries comprising same | |
GB9708219D0 (en) | Method of determining the characteristics of a magnetic sample | |
EP0999447A4 (en) | Method for detecting or predicting ischemic diseases | |
FI962371A (en) | Method for preparing combinatorial compound libraries | |
ZA974027B (en) | Method for characterization of combinatorial libraries. | |
AU9801598A (en) | Method and apparatus for screening catalyst libraries | |
EP0839075A4 (en) | Apparatus and method for washing a pipette probe | |
EP0699909A3 (en) | Method for determining fibrinogen and reagent for determination thereof | |
EP1025437A4 (en) | A method for determining the affinity of proteins for chemical agents during screening of combinatorial libraries | |
GB9701245D0 (en) | Method of screening compounds | |
GB9721892D0 (en) | Apparatus for and method of testing a sample | |
PL346565A1 (en) | Method for the rapid screening of analytes | |
EP1046036A4 (en) | Methods for obtaining probes of peptide function | |
EP0946556A4 (en) | Combinatorial process for preparing hydrofuroquinoline libraries |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980929 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): BE CH DE ES FR GB IT LI NL |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7G 01N 33/00 A, 7G 01N 33/53 B, 7G 01N 33/543 B, 7G 01N 33/566 B, 7G 01N 33/68 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20020910 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): BE CH DE ES FR GB IT LI NL |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20031108 |