ZA974027B - Method for characterization of combinatorial libraries. - Google Patents

Method for characterization of combinatorial libraries.

Info

Publication number
ZA974027B
ZA974027B ZA9704027A ZA974027A ZA974027B ZA 974027 B ZA974027 B ZA 974027B ZA 9704027 A ZA9704027 A ZA 9704027A ZA 974027 A ZA974027 A ZA 974027A ZA 974027 B ZA974027 B ZA 974027B
Authority
ZA
South Africa
Prior art keywords
characterization
combinatorial libraries
combinatorial
libraries
Prior art date
Application number
ZA9704027A
Inventor
Lawrence Paul Wennogle
Michele Ann Kelly
Hongbin Liang
Christine Goeller
Hans Mathis Thoma
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA974027B publication Critical patent/ZA974027B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
ZA9704027A 1996-05-10 1997-05-09 Method for characterization of combinatorial libraries. ZA974027B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1754596P 1996-05-10 1996-05-10

Publications (1)

Publication Number Publication Date
ZA974027B true ZA974027B (en) 1998-01-23

Family

ID=21783193

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9704027A ZA974027B (en) 1996-05-10 1997-05-09 Method for characterization of combinatorial libraries.

Country Status (3)

Country Link
AU (1) AU2889097A (en)
WO (1) WO1997043301A2 (en)
ZA (1) ZA974027B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6191418B1 (en) 1998-03-27 2001-02-20 Synsorb Biotech, Inc. Device for delivery of multiple liquid sample streams to a mass spectrometer
US6054047A (en) 1998-03-27 2000-04-25 Synsorb Biotech, Inc. Apparatus for screening compound libraries
CA2240325A1 (en) * 1998-03-27 1998-11-14 Synsorb Biotech, Inc. Methods for screening compound libraries
US6613575B1 (en) 1998-03-27 2003-09-02 Ole Hindsgaul Methods for screening compound libraries
US6720190B1 (en) 1998-03-27 2004-04-13 Ole Hindsgaul Methods for screening compound libraries
EP1048950A1 (en) * 1999-04-26 2000-11-02 ScreenTec B.V. Identification of ligands for orphan receptors using on-line coupling of mass spectrometry to continuous-flow separation techniques
DE19943743C2 (en) * 1999-09-03 2002-02-07 Jerini Biotools Gmbh Procedure for the identification of binding partners with position-specific arrays
AU2001278872A1 (en) * 2000-07-06 2002-01-21 Genvec, Inc. Method of identifying a binding partner of a gene product
JP4823470B2 (en) 2000-07-13 2011-11-24 シーティー−コンセプト・ホールディング・アクチェンゲゼルシャフト Method and apparatus for controlling transient state of power semiconductor switch according to the state
EP1314035A1 (en) 2000-08-14 2003-05-28 Surface Logix, Inc. Pathways arrays
DE10125258A1 (en) 2001-05-23 2003-01-09 November Ag Molekulare Medizin Method for determining the binding behavior of ligands that specifically bind to target molecules
JP4659831B2 (en) * 2005-07-29 2011-03-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 Method for analyzing the binding power of a protein to a compound
US20100227414A1 (en) * 2009-03-05 2010-09-09 Trex Enterprises Corp. Affinity capture mass spectroscopy with a porous silicon biosensor
AU2013359426A1 (en) * 2012-12-10 2015-07-09 Fred Hutchinson Cancer Research Center Lipocalin fusion partners

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532167A (en) * 1994-01-07 1996-07-02 Beth Israel Hospital Substrate specificity of protein kinases
WO1995025737A1 (en) * 1994-03-23 1995-09-28 The Penn State Research Foundation Method for identifying members of combinatorial libraries
US5891742A (en) * 1995-01-19 1999-04-06 Chiron Corporation Affinity selection of ligands by mass spectroscopy
GB9507366D0 (en) * 1995-04-08 1995-05-31 Zeneca Ltd Assay

Also Published As

Publication number Publication date
WO1997043301A2 (en) 1997-11-20
AU2889097A (en) 1997-12-05
WO1997043301A3 (en) 1998-02-19

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