|
GB323103A
(en)
|
1928-12-07 |
1929-12-24 |
Fred Cunningham Firth |
Improvements relating to shaper mechanism for winding yarn on weft bobbins in spinning mules
|
|
US4057685A
(en)
|
1972-02-02 |
1977-11-08 |
Abbott Laboratories |
Chemically modified endotoxin immunizing agent
|
|
US4356170A
(en)
|
1981-05-27 |
1982-10-26 |
Canadian Patents & Development Ltd. |
Immunogenic polysaccharide-protein conjugates
|
|
US4673574A
(en)
|
1981-08-31 |
1987-06-16 |
Anderson Porter W |
Immunogenic conjugates
|
|
SE8205892D0
(sv)
|
1982-10-18 |
1982-10-18 |
Bror Morein |
Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
|
|
US4459286A
(en)
|
1983-01-31 |
1984-07-10 |
Merck & Co., Inc. |
Coupled H. influenzae type B vaccine
|
|
US4663160A
(en)
|
1983-03-14 |
1987-05-05 |
Miles Laboratories, Inc. |
Vaccines for gram-negative bacteria
|
|
US4761283A
(en)
|
1983-07-05 |
1988-08-02 |
The University Of Rochester |
Immunogenic conjugates
|
|
US6090406A
(en)
|
1984-04-12 |
2000-07-18 |
The Liposome Company, Inc. |
Potentiation of immune responses with liposomal adjuvants
|
|
US5916588A
(en)
|
1984-04-12 |
1999-06-29 |
The Liposome Company, Inc. |
Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
|
|
US4695624A
(en)
|
1984-05-10 |
1987-09-22 |
Merck & Co., Inc. |
Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
|
|
US4882317A
(en)
|
1984-05-10 |
1989-11-21 |
Merck & Co., Inc. |
Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency
|
|
US4808700A
(en)
|
1984-07-09 |
1989-02-28 |
Praxis Biologics, Inc. |
Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
|
|
IT1187753B
(it)
|
1985-07-05 |
1987-12-23 |
Sclavo Spa |
Coniugati glicoproteici ad attivita' immunogenica trivalente
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
NL8802046A
(nl)
|
1988-08-18 |
1990-03-16 |
Gen Electric |
Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen.
|
|
AU627226B2
(en)
|
1988-08-25 |
1992-08-20 |
Liposome Company, Inc., The |
Influenza vaccine and novel adjuvants
|
|
HU212924B
(en)
|
1989-05-25 |
1996-12-30 |
Chiron Corp |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
CU22302A1
(es)
*
|
1990-09-07 |
1995-01-31 |
Cigb |
Secuencia nucleotidica codificante para una proteina de la membrana externa de neisseria meningitidis y uso de dicha proteina en preparados vacunales
|
|
US5153312A
(en)
|
1990-09-28 |
1992-10-06 |
American Cyanamid Company |
Oligosaccharide conjugate vaccines
|
|
UA40597C2
(uk)
|
1992-06-25 |
2001-08-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Вакцинна композиція,спосіб лікування ссавців, що страждають або сприйнятливі до інфекції, спосіб лікування ссавців, що страждають на рак, спосіб одержання вакцинної композиції, композиція ад'ювантів
|
|
EP0658118B1
(en)
|
1992-08-31 |
2002-01-23 |
Baxter Healthcare S.A. |
Vaccines against group c neisseria meningitidis
|
|
US5425946A
(en)
|
1992-08-31 |
1995-06-20 |
North American Vaccine, Inc. |
Vaccines against group C Neisseria meningitidis
|
|
EP1175912A1
(en)
|
1993-03-23 |
2002-01-30 |
SmithKline Beecham Biologics SA |
Vaccine compositions containing 3-O deacylated monophosphoryl lipid A
|
|
AU678613B2
(en)
|
1993-09-22 |
1997-06-05 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Method of activating soluble carbohydrate using novel cyanylating reagents for the production of immunogenic constructs
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
|
US6429199B1
(en)
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
AUPM873294A0
(en)
|
1994-10-12 |
1994-11-03 |
Csl Limited |
Saponin preparations and use thereof in iscoms
|
|
UA56132C2
(uk)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
|
|
FR2734484B1
(fr)
|
1995-05-24 |
1997-06-27 |
Pasteur Merieux Serums Vacc |
Composition vaccinale liquide et procede de fabrication
|
|
DE69615362T3
(de)
|
1995-06-07 |
2006-07-20 |
Smithkline Beecham Biologicals S.A. |
Impfstoff mit einem polysaccharidantigen-trägerprotein-konjugat und einem trägerprotein
|
|
JP4850987B2
(ja)
|
1995-06-23 |
2012-01-11 |
グラクソスミスクライン・バイオロジカルス・ソシエテ・アノニム |
リン酸アルミニウム上に吸着したポリサッカライド結合抗原を含むワクチン組成物
|
|
GB9513261D0
(en)
|
1995-06-29 |
1995-09-06 |
Smithkline Beecham Biolog |
Vaccines
|
|
WO1998040100A1
(en)
|
1997-03-10 |
1998-09-17 |
Ottawa Civic Loeb Research Institute |
USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE AS AN ADJUVANT
|
|
US6818222B1
(en)
|
1997-03-21 |
2004-11-16 |
Chiron Corporation |
Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
|
|
US6299881B1
(en)
|
1997-03-24 |
2001-10-09 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
|
|
FR2763244B1
(fr)
|
1997-05-14 |
2003-08-01 |
Pasteur Merieux Serums Vacc |
Composition vaccinale multivalente a porteur mixte
|
|
GB9712347D0
(en)
|
1997-06-14 |
1997-08-13 |
Smithkline Beecham Biolog |
Vaccine
|
|
DE69815692T2
(de)
|
1997-09-05 |
2004-04-29 |
Glaxosmithkline Biologicals S.A. |
Öl in wasser emulsionen mit saponinen
|
|
GB9725084D0
(en)
|
1997-11-28 |
1998-01-28 |
Medeva Europ Ltd |
Vaccine compositions
|
|
EP1053015A2
(en)
|
1998-02-12 |
2000-11-22 |
American Cyanamid Company |
Pneumococcal and meningococcal vaccines formulated with interleukin-12
|
|
US7018637B2
(en)
|
1998-02-23 |
2006-03-28 |
Aventis Pasteur, Inc |
Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
|
|
US6303114B1
(en)
|
1998-03-05 |
2001-10-16 |
The Medical College Of Ohio |
IL-12 enhancement of immune responses to T-independent antigens
|
|
AU746163B2
(en)
|
1998-04-09 |
2002-04-18 |
Smithkline Beecham Biologicals (Sa) |
Adjuvant compositions
|
|
US6562798B1
(en)
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
|
MXPA01000352A
(es)
|
1998-07-15 |
2002-06-04 |
Novozymes As |
Varientes de glucoamilasa.
|
|
GB9817052D0
(en)
|
1998-08-05 |
1998-09-30 |
Smithkline Beecham Biolog |
Vaccine
|
|
CN1263510C
(zh)
|
1998-08-19 |
2006-07-12 |
巴克斯特健康护理股份有限公司 |
多糖-蛋白质缀合物或寡糖-蛋白质缀合物、其制备方法及其应用
|
|
CA2773698C
(en)
|
1998-10-16 |
2015-05-19 |
Glaxosmithkline Biologicals S.A. |
Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof
|
|
RU2161037C2
(ru)
*
|
1998-12-24 |
2000-12-27 |
Алексахина Нина Николаевна |
Низкотоксичный, низкопирогенный липоолигосахарид из neisseria meningitidis
|
|
MY125202A
(en)
|
1999-03-19 |
2006-07-31 |
Smithkline Beecham Biologicals S A |
Vaccine
|
|
HK1046861A1
(zh)
|
1999-09-24 |
2003-01-30 |
Smithkline Beecham Biologicals S.A. |
包括聚氧乙烯烷基酯或者醚以及至少一種非離子表面活性劑的佐劑
|
|
IL148672A0
(en)
|
1999-09-24 |
2002-09-12 |
Smithkline Beecham Biolog |
Use of combination of polyxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines
|
|
ATE476988T1
(de)
*
|
2000-01-17 |
2010-08-15 |
Novartis Vaccines & Diagnostic |
Membranvesikel (omv) impfstoff, der n. meningitidis serogruppe b membranproteine enthält
|
|
AU3108001A
(en)
|
2000-01-20 |
2001-12-24 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory nucleic acids for inducing a th2 immune response
|
|
EP2277541A1
(en)
|
2000-06-29 |
2011-01-26 |
SmithKline Beecham Biologicals S.A. |
Multivalent vaccine composition
|
|
GB0108364D0
(en)
|
2001-04-03 |
2001-05-23 |
Glaxosmithkline Biolog Sa |
Vaccine composition
|
|
JP2004509970A
(ja)
|
2000-09-26 |
2004-04-02 |
ハイブリドン・インコーポレイテッド |
位置的化学変化による免疫刺激オリゴヌクレオチドアナログの免疫刺激活性の調節
|
|
EP1355673B1
(en)
*
|
2001-01-23 |
2012-05-30 |
Sanofi Pasteur Inc. |
Multivalent meningococcal polysaccharide-protein conjugate vaccine
|
|
GB0115176D0
(en)
*
|
2001-06-20 |
2001-08-15 |
Chiron Spa |
Capular polysaccharide solubilisation and combination vaccines
|
|
EP1409013B1
(en)
|
2001-07-26 |
2009-11-18 |
Novartis Vaccines and Diagnostics S.r.l. |
Vaccines comprising aluminium adjuvants and histidine
|
|
CN1599623B
(zh)
|
2001-09-14 |
2011-05-11 |
赛托斯生物技术公司 |
免疫刺激物向病毒样颗粒内的包装:制备方法与用途
|
|
WO2003024480A2
(en)
|
2001-09-14 |
2003-03-27 |
Cytos Biotechnology Ag |
In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles
|
|
WO2003035836A2
(en)
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
|
BR0308768A
(pt)
|
2002-03-26 |
2005-02-15 |
Chiron Srl |
Sacarìdeos modificados possuindo estabilidade melhorada em água
|
|
RU2378008C2
(ru)
|
2002-05-14 |
2010-01-10 |
Новартис Вэксинес Энд Дайэгностикс С.Р.Л. |
Комбинированные вакцины против бактериального менингита для введения через слизистую оболочку
|
|
GB0302218D0
(en)
|
2003-01-30 |
2003-03-05 |
Chiron Sri |
Vaccine formulation & Mucosal delivery
|
|
AU2003257003A1
(en)
|
2002-07-30 |
2004-02-16 |
Baxter Healthcare S.A. |
Chimeric multivalent polysaccharide conjugate vaccines
|
|
GB0217909D0
(en)
|
2002-08-01 |
2002-09-11 |
Du Pont |
Chintzed stretch fabrics
|
|
HUE031886T2
(en)
|
2002-10-11 |
2017-08-28 |
Glaxosmithkline Biologicals Sa |
Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines
|
|
US7521062B2
(en)
|
2002-12-27 |
2009-04-21 |
Novartis Vaccines & Diagnostics, Inc. |
Thiosemicarbazones as anti-virals and immunopotentiators
|
|
ES2391770T3
(es)
|
2003-01-21 |
2012-11-29 |
Novartis Vaccines And Diagnostics, Inc. |
Uso de compuestos de triptantrina para la potenciación inmune
|
|
PT2191844E
(pt)
|
2003-01-30 |
2014-06-04 |
Novartis Ag |
Vacinas injetáveis contra múltiplos serogrupos meningocócicos
|
|
BRPI0410423A
(pt)
*
|
2003-05-07 |
2006-06-06 |
Sanofi Pasteur Inc |
processo de imunogenicidade melhorada para vacinação meningocócica
|
|
JP2006528936A
(ja)
|
2003-05-07 |
2006-12-28 |
アヴェンティス パストゥール インコーポレイテッド |
多価髄膜炎菌誘導体化多糖−タンパク質複合体およびワクチン
|
|
GB0313916D0
(en)
|
2003-06-16 |
2003-07-23 |
Glaxosmithkline Biolog Sa |
Vaccine composition
|
|
BRPI0411875A
(pt)
|
2003-06-23 |
2006-08-08 |
Sanofi Pasteur Inc |
método de imunização contra os sorogrupos a e c de neisseria meningitidis
|
|
EP2366403B1
(en)
*
|
2003-08-06 |
2014-10-08 |
The Government of The United States of America, as represented by The Secretary, Department of Health and Human Services |
Polysaccharide-protein conjugate vaccines
|
|
GB0500787D0
(en)
|
2005-01-14 |
2005-02-23 |
Chiron Srl |
Integration of meningococcal conjugate vaccination
|
|
DK1740217T3
(da)
*
|
2004-04-30 |
2011-09-26 |
Novartis Ag |
Meningokok-konjugat-vaccination
|
|
AU2006327023A1
(en)
|
2005-12-23 |
2007-06-28 |
Glaxosmithkline Biologicals Sa |
Conjugate vaccines
|