JP2007534727A - 細胞接着を増加させることにより皮膚の弾力を改善させる化粧品の組成物の調整におけるxikvavペプチドの使用 - Google Patents
細胞接着を増加させることにより皮膚の弾力を改善させる化粧品の組成物の調整におけるxikvavペプチドの使用 Download PDFInfo
- Publication number
- JP2007534727A JP2007534727A JP2007510051A JP2007510051A JP2007534727A JP 2007534727 A JP2007534727 A JP 2007534727A JP 2007510051 A JP2007510051 A JP 2007510051A JP 2007510051 A JP2007510051 A JP 2007510051A JP 2007534727 A JP2007534727 A JP 2007534727A
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- cosmetic composition
- group
- xikvav
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- JRXHLZJTPJEZAM-ONEGZZNKSA-N CC1CC(/C=C/C)=CC1 Chemical compound CC1CC(/C=C/C)=CC1 JRXHLZJTPJEZAM-ONEGZZNKSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
【選択図】
Description
免疫染色活性試験は、SIKVAVがα6インテグリンとラミニンVの発現を促進する活性があるかどうかを決定するために、人間の線維芽細胞とケラチノサイトで行われた(図3、4、5、及び62、3、4、及び5)。
(実施例2)
細胞レベルでの接着の過程は、第2の実施例の活性試験における、実験室内の線維芽細胞の培養物により解明される。
(実施例3)
この実施形態は、ガラス器内の、ケラチノサイトの一般化学式XIKVAVのペプチドへの細胞接着の評価と、それらの間の比較評価を示す。
Claims (17)
- Xは水素またはセリンであることを特徴とする請求項1に記載の使用。
- Xはパルミトイル基またはデカノイル基であることを特徴とする請求項1に記載の使用。
- Yはアミノ基であることを特徴とする請求項1に記載の使用。
- Yは水酸基であることを特徴とする請求項1に記載の使用。
- Yはチオール基であることを特徴とする請求項1に記載の使用。
- 皮膚の細胞はケラチノサイト(keratinocytes)であることを特徴とする請求項1から6のいずれか1つに記載の使用。
- 生物接着ペプチドはアルファ6インテグリン及びラミニンVであることを特徴とする請求項1から7のいずれか1つに記載の使用。
- 化粧品の組成物の調整における請求項1から8のいずれか1つに記載のペプチドの使用。
- 皮膚の弾力を増加させる化粧品の組成物の調整における請求項1から9のいずれか1つに記載のペプチドの使用。
- ジェル、乳液、クリーム、化粧水、シャンプー、美容液(serum)の形態で提供されることを特徴とする請求項11に記載の化粧品の組成物。
- 皮膚の弾力を増加させることを特徴とする請求項11または12に記載の化粧品の組成物。
- 皮膚の細胞の相互の、及び基底膜との接着を増加させることにより皮膚の弾力を増加させる効果を特徴とする請求項13に記載の化粧品の組成物。
- XIKVAVペプチドの量が12重量%以下であることを特徴とする請求項11から14のいずれか1つに記載の化粧品の組成物。
- 以下の成分を以下の重量%で好適に含むことを特徴とする請求項11から15に記載の化粧品の組成物。
ペプチド 0.001−10
ワセリン(petrolaum) 0−10
トリエタノールアミン 0−10
BHT 0−10
フェノキシエタノール 0−10
メチルパラベン 0−10
ブチルパラベン 0−10
ブチルパラベン 0−10
プロピルパラベン 0−10
イソプチルパラベン 0−10
ステアリン酸 0−10
蜜蝋(Beeswax) 0−10
カルボマー(carbomer) 0−10
ジメチコノール 0−10
シクロメチコン 0−1
グリセリン 0−10
セチルステアリン酸 0−10
香料 0−10
水 100とする量 - XIKVAVペプチドの量が5重量%以下であることを特徴とする請求項11から16に記載の化粧品の組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ESP200401018 | 2004-04-28 | ||
ES200401018A ES2293753B1 (es) | 2004-04-28 | 2004-04-28 | Uso de peptidos xikvav en preparacion de composiciones cosmeticas para mejorar la firmeza de la piel mediante el aumento de la adhesion celular. |
PCT/ES2005/000175 WO2005105029A1 (es) | 2004-04-28 | 2005-04-05 | Uso de péptidos xikvav en preparación de composiciones cosméticas para mejorar la firmeza de la piel mediante el aumento de la adhesión celular |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007534727A true JP2007534727A (ja) | 2007-11-29 |
JP5384824B2 JP5384824B2 (ja) | 2014-01-08 |
Family
ID=35241406
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007510051A Active JP5384824B2 (ja) | 2004-04-28 | 2005-04-05 | 細胞接着を増加させることにより皮膚の弾力を改善させる化粧品の組成物の調整におけるxikvavペプチドの使用 |
Country Status (14)
Country | Link |
---|---|
US (1) | US7943156B2 (ja) |
EP (1) | EP1741421B1 (ja) |
JP (1) | JP5384824B2 (ja) |
KR (1) | KR101353748B1 (ja) |
CN (1) | CN1964694A (ja) |
AU (1) | AU2005237268B2 (ja) |
BR (1) | BRPI0510257B1 (ja) |
CA (1) | CA2564312C (ja) |
ES (2) | ES2293753B1 (ja) |
MX (1) | MXPA06012495A (ja) |
PL (1) | PL1741421T3 (ja) |
RU (1) | RU2371167C2 (ja) |
WO (1) | WO2005105029A1 (ja) |
ZA (1) | ZA200608996B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2017125034A (ja) * | 2008-10-12 | 2017-07-20 | マサチューセッツ インスティテュート オブ テクノロジー | 免疫ナノ治療剤による抗原提示細胞のターゲティング |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2322882B1 (es) * | 2006-10-25 | 2010-04-22 | Lipotec Sa | Peptidos inhibidores de la exocitosis neuronal. |
EP1992332A1 (en) | 2007-05-08 | 2008-11-19 | Tupperware Products S.A. | Cosmetic anti ageing skin care compositions |
US8916682B2 (en) | 2007-07-05 | 2014-12-23 | Nissan Chemical Industries, Ltd. | Lipid peptide and hydrogel |
ES2342754B1 (es) * | 2008-10-03 | 2011-05-11 | Lipotec, S.A. | Peptidos utiles en el tratamiento y/o cuidado de la piel, mucosas, cuero cabelludo y/o cabello y su uso en composiciones cosmeticas o farmaceuticas. |
ES2397890B1 (es) * | 2011-03-25 | 2014-02-07 | Lipotec, S.A. | Péptidos útiles en el tratamiento y/o cuidado de la piel y/o mucosas y su uso en composiciones cosméticas o farmacéuticas. |
KR20160083884A (ko) | 2013-11-01 | 2016-07-12 | 스페리움 바이오메드 에스.엘. | 치료제 및 미용제의 경피 전달을 위한 봉입체 |
SG11201703214SA (en) | 2014-10-31 | 2017-05-30 | Lubrizol Advanced Mat Inc | Thermoplastic polyurethane film for delivery of active agents to skin surfaces |
CN108473652A (zh) | 2015-11-05 | 2018-08-31 | 路博润先进材料公司 | 可热成型的双网络水凝胶组合物 |
US10086035B2 (en) | 2016-02-04 | 2018-10-02 | ALASTIN Skincare, Inc. | Compositions and methods for invasive and non-invasive procedural skincare |
CN111182914A (zh) | 2017-08-03 | 2020-05-19 | 阿拉斯廷护肤公司 | 用于改善皮肤松弛和身体轮廓的组合物和方法 |
WO2020028694A1 (en) | 2018-08-02 | 2020-02-06 | ALASTIN Skincare, Inc. | Liposomal compositions and methods of use |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10147515A (ja) * | 1996-11-20 | 1998-06-02 | Shiseido Co Ltd | 皮膚外用剤 |
JPH10316581A (ja) * | 1997-05-15 | 1998-12-02 | Kuraray Co Ltd | 医療用手当材およびそれに用いる新規なペプチド |
JPH11255657A (ja) * | 1998-03-12 | 1999-09-21 | Q P Corp | 線維芽細胞増殖剤及びこれを配合した皮膚外用剤 |
JP2000143531A (ja) * | 1998-09-09 | 2000-05-23 | Kuraray Co Ltd | 神経再生用材料 |
JP2000309521A (ja) * | 1999-02-23 | 2000-11-07 | Shiseido Co Ltd | 皮膚外用剤 |
JP2002045419A (ja) * | 2000-07-31 | 2002-02-12 | Sanyo Chem Ind Ltd | 創傷被覆材 |
JP2003038633A (ja) * | 2001-07-26 | 2003-02-12 | Sanyo Chem Ind Ltd | 創傷被覆材 |
JP2003089648A (ja) * | 2001-07-10 | 2003-03-28 | Alcare Co Ltd | 創傷治療材料及びこれに用いる創傷被覆材 |
JP2003171225A (ja) * | 2001-11-30 | 2003-06-17 | Fancl Corp | インテグリンα6β4産生促進用組成物 |
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JP2004510811A (ja) * | 2000-10-10 | 2004-04-08 | リポテック,エス.アー. | 抗癌剤を封入したリポソーム及び悪性腫瘍の治療におけるその使用方法 |
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-
2004
- 2004-04-28 ES ES200401018A patent/ES2293753B1/es not_active Expired - Fee Related
-
2005
- 2005-04-05 JP JP2007510051A patent/JP5384824B2/ja active Active
- 2005-04-05 EP EP05731868.5A patent/EP1741421B1/en active Active
- 2005-04-05 CN CNA2005800184945A patent/CN1964694A/zh active Pending
- 2005-04-05 AU AU2005237268A patent/AU2005237268B2/en active Active
- 2005-04-05 MX MXPA06012495A patent/MXPA06012495A/es active IP Right Grant
- 2005-04-05 WO PCT/ES2005/000175 patent/WO2005105029A1/es active Application Filing
- 2005-04-05 RU RU2006137956/15A patent/RU2371167C2/ru not_active IP Right Cessation
- 2005-04-05 US US11/587,878 patent/US7943156B2/en active Active
- 2005-04-05 BR BRPI0510257-0A patent/BRPI0510257B1/pt active IP Right Grant
- 2005-04-05 ZA ZA200608996A patent/ZA200608996B/xx unknown
- 2005-04-05 ES ES05731868.5T patent/ES2501941T3/es active Active
- 2005-04-05 KR KR1020067022761A patent/KR101353748B1/ko active IP Right Grant
- 2005-04-05 CA CA2564312A patent/CA2564312C/en not_active Expired - Fee Related
- 2005-04-05 PL PL05731868T patent/PL1741421T3/pl unknown
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH10147515A (ja) * | 1996-11-20 | 1998-06-02 | Shiseido Co Ltd | 皮膚外用剤 |
JPH10316581A (ja) * | 1997-05-15 | 1998-12-02 | Kuraray Co Ltd | 医療用手当材およびそれに用いる新規なペプチド |
JPH11255657A (ja) * | 1998-03-12 | 1999-09-21 | Q P Corp | 線維芽細胞増殖剤及びこれを配合した皮膚外用剤 |
JP2000143531A (ja) * | 1998-09-09 | 2000-05-23 | Kuraray Co Ltd | 神経再生用材料 |
JP2000309521A (ja) * | 1999-02-23 | 2000-11-07 | Shiseido Co Ltd | 皮膚外用剤 |
JP2002045419A (ja) * | 2000-07-31 | 2002-02-12 | Sanyo Chem Ind Ltd | 創傷被覆材 |
JP2004510811A (ja) * | 2000-10-10 | 2004-04-08 | リポテック,エス.アー. | 抗癌剤を封入したリポソーム及び悪性腫瘍の治療におけるその使用方法 |
JP2003089648A (ja) * | 2001-07-10 | 2003-03-28 | Alcare Co Ltd | 創傷治療材料及びこれに用いる創傷被覆材 |
JP2003038633A (ja) * | 2001-07-26 | 2003-02-12 | Sanyo Chem Ind Ltd | 創傷被覆材 |
JP2003171225A (ja) * | 2001-11-30 | 2003-06-17 | Fancl Corp | インテグリンα6β4産生促進用組成物 |
JP2003226655A (ja) * | 2002-01-31 | 2003-08-12 | Fancl Corp | ラミニン5産生促進剤およびインテグリンα6β4産生促進剤を含む組成物 |
JP2003238429A (ja) * | 2002-02-12 | 2003-08-27 | Kyoei Kagaku Kogyo Kk | 線維芽細胞賦活剤及びこれを含む皮膚外用剤 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2017125034A (ja) * | 2008-10-12 | 2017-07-20 | マサチューセッツ インスティテュート オブ テクノロジー | 免疫ナノ治療剤による抗原提示細胞のターゲティング |
Also Published As
Publication number | Publication date |
---|---|
AU2005237268B2 (en) | 2010-12-23 |
RU2006137956A (ru) | 2008-06-10 |
CA2564312C (en) | 2014-03-25 |
CA2564312A1 (en) | 2005-11-10 |
WO2005105029A1 (es) | 2005-11-10 |
AU2005237268A1 (en) | 2005-11-10 |
ZA200608996B (en) | 2008-07-30 |
ES2501941T3 (es) | 2014-10-02 |
RU2371167C2 (ru) | 2009-10-27 |
JP5384824B2 (ja) | 2014-01-08 |
MXPA06012495A (es) | 2007-01-31 |
CN1964694A (zh) | 2007-05-16 |
KR20070095752A (ko) | 2007-10-01 |
ES2293753A1 (es) | 2008-03-16 |
US20080085852A1 (en) | 2008-04-10 |
BRPI0510257A (pt) | 2008-01-02 |
US7943156B2 (en) | 2011-05-17 |
BRPI0510257B1 (pt) | 2014-12-02 |
ES2293753B1 (es) | 2009-03-16 |
EP1741421A1 (en) | 2007-01-10 |
PL1741421T3 (pl) | 2014-11-28 |
EP1741421B1 (en) | 2014-06-25 |
KR101353748B1 (ko) | 2014-01-21 |
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