|
KR100330553B1
(ko)
*
|
1993-10-01 |
2002-11-27 |
노파르티스 아게 |
약물학적활성피리딘유도체및그의제조방법
|
|
WO1995015973A1
(en)
|
1993-12-06 |
1995-06-15 |
Cytel Corporation |
Cs-1 peptidomimetics, compositions and methods of using the same
|
|
US5510332A
(en)
|
1994-07-07 |
1996-04-23 |
Texas Biotechnology Corporation |
Process to inhibit binding of the integrin α4 62 1 to VCAM-1 or fibronectin and linear peptides therefor
|
|
WO1996001644A1
(en)
|
1994-07-11 |
1996-01-25 |
Athena Neurosciences, Inc. |
Inhibitors of leukocyte adhesion
|
|
US5811391A
(en)
|
1994-08-25 |
1998-09-22 |
Cytel Corporation |
Cyclic CS-1 peptidomimetics, compositions and methods of using same
|
|
GB9524630D0
(en)
|
1994-12-24 |
1996-01-31 |
Zeneca Ltd |
Chemical compounds
|
|
WO1996031206A2
(en)
|
1995-04-07 |
1996-10-10 |
Warner-Lambert Company |
Flavones and coumarins as agents for the treatment of atherosclerosis
|
|
NZ321575A
(en)
|
1995-10-30 |
1999-05-28 |
Janssen Pharmaceutica Nv |
1-(1,2-disubstituted piperidinyl)-4- substituted piperazine derivatives
|
|
GB9522372D0
(en)
|
1995-11-01 |
1996-01-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5704960A
(en)
|
1995-12-20 |
1998-01-06 |
Corning, Inc. |
Method of forming an optical fiber for reduced polarization effects in amplifiers
|
|
GB9603741D0
(en)
|
1996-02-22 |
1996-04-24 |
Lin Mei |
Treatment of water by electrolysis
|
|
CA2258044C
(en)
*
|
1996-07-01 |
2007-09-04 |
Schering Corporation |
Muscarinic antagonists
|
|
US5935958A
(en)
|
1996-07-01 |
1999-08-10 |
Schering Corporation |
Muscarinic antagonists
|
|
JP2000516210A
(ja)
|
1996-07-12 |
2000-12-05 |
ロイコサイト,インコーポレーテッド |
ケモカインレセプターアンタゴニストとその使用方法
|
|
EP1001764A4
(en)
|
1997-05-29 |
2005-08-24 |
Merck & Co Inc |
HETEROCYCLIC AMIDE COMPOUNDS AS INHIBITORS OF CELL ADHESION
|
|
EP1017382B1
(en)
|
1997-05-29 |
2006-03-01 |
Merck & Co., Inc. (a New Jersey corp.) |
Biarylalkanoic acids as cell adhesion inhibitors
|
|
JP2002501518A
(ja)
|
1997-05-30 |
2002-01-15 |
セルテック セラピューティックス リミテッド |
抗炎症性チロシン誘導体
|
|
JP2001517246A
(ja)
|
1997-06-23 |
2001-10-02 |
田辺製薬株式会社 |
α▲下4▼β▲下1▼媒介細胞接着の阻止剤
|
|
US6312689B1
(en)
|
1998-07-23 |
2001-11-06 |
Millennium Pharmaceuticals, Inc. |
Anti-CCR2 antibodies and methods of use therefor
|
|
CA2371583C
(en)
*
|
1999-05-04 |
2005-09-13 |
Schering Corporation |
Piperazine derivatives useful as ccr5 antagonists
|
|
US6387930B1
(en)
|
1999-05-04 |
2002-05-14 |
Schering Corporation |
Piperidine derivatives useful as CCR5 antagonists
|
|
US7825121B2
(en)
|
1999-05-04 |
2010-11-02 |
Schering Corporation |
Piperazine derivatives useful as CCR5 antagonists
|
|
HK1039330B
(en)
|
1999-05-04 |
2005-12-09 |
Schering Corporation |
Piperidine derivatives useful as ccr5 antagonists
|
|
US6635646B1
(en)
|
1999-05-04 |
2003-10-21 |
Schering Corporation |
Pegylated interferon alfa-CCR5 antagonist combination HIV therapy
|
|
US6391865B1
(en)
|
1999-05-04 |
2002-05-21 |
Schering Corporation |
Piperazine derivatives useful as CCR5 antagonists
|
|
ES2165274B1
(es)
|
1999-06-04 |
2003-04-01 |
Almirall Prodesfarma Sa |
Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
|
|
EP1373206B1
(en)
|
2001-03-29 |
2008-12-24 |
Schering Corporation |
Aryl oxime-piperazines useful as ccr5 antagonists
|
|
PL364560A1
(en)
|
2001-03-29 |
2004-12-13 |
Schering Corporation |
Ccr5 antagonists useful for treating aids
|
|
AR036366A1
(es)
|
2001-08-29 |
2004-09-01 |
Schering Corp |
Derivados de piperidina utiles como antagonistas de ccr5, composiciones farmaceuticas, el uso de dichos derivados para la fabricación de un medicamento y un kit
|
|
SE0103818D0
(sv)
|
2001-11-15 |
2001-11-15 |
Astrazeneca Ab |
Chemical compounds
|
|
CN100436449C
(zh)
|
2001-11-29 |
2008-11-26 |
先灵公司 |
作为ccr5-拮抗剂用于治疗aids和相关的hiv感染的药用盐的制备
|
|
JP2005529067A
(ja)
|
2002-01-22 |
2005-09-29 |
メルク エンド カムパニー インコーポレーテッド |
ケモカイン受容体ccr5モジュレータによるストレス応答の治療
|
|
CN100396676C
(zh)
*
|
2002-03-29 |
2008-06-25 |
先灵公司 |
作为ccr5拮抗药的哌啶和哌嗪化合物的合成
|
|
WO2004002960A1
(en)
|
2002-06-27 |
2004-01-08 |
Schering Aktiengesellschaft |
Substituted quinoline ccr5 receptor antagonists
|
|
GB0223223D0
(en)
|
2002-10-07 |
2002-11-13 |
Novartis Ag |
Organic compounds
|
|
MY141736A
(en)
|
2002-10-08 |
2010-06-15 |
Elanco Animal Health Ireland |
Substituted 1,4-di-piperidin-4-yi-piperazine derivatives and their use as neurokinin antagonists
|
|
MXPA05005660A
(es)
|
2002-11-27 |
2005-10-18 |
Incyte Corp |
Derivados de 3-aminopirrolidina como moduladores de receptores de quimocina.
|
|
MXPA05006485A
(es)
|
2002-12-17 |
2005-08-26 |
Schering Corp |
Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades dependientes de androgeno.
|
|
PE20040769A1
(es)
|
2002-12-18 |
2004-11-06 |
Schering Corp |
Derivados de piperidina utiles como antagonisas ccr5
|
|
AU2002368487A1
(en)
|
2002-12-23 |
2004-07-14 |
Janssen Pharmaceutica N.V. |
Substituted 1,4-di-piperidin-4-yl-piperazine derivatives and their use as tachykinin antagonists
|
|
CA2509406C
(en)
|
2002-12-23 |
2012-07-03 |
Janssen Pharmaceutica N.V. |
Substituted 1-piperidin-4-yl-4-azetidin-3-yl-piperazine derivatives and their use as neurokinin antagonists
|
|
JO2696B1
(en)
|
2002-12-23 |
2013-03-03 |
شركة جانسين فارماسوتيكا ان. في |
Derivatives of 1-piperdine-4-yl-4-biprolidine-3-yl-piperazine substituted and used as quinine antagonists
|
|
JO2485B1
(en)
|
2002-12-23 |
2009-01-20 |
شركة جانسين فارماسوتيكا ان. في |
1-Piperidine-3-Yl-4-Piperidine-4-Yl-Piperazine derivatives substituted and used as quinine antagonists
|
|
WO2004056805A1
(en)
|
2002-12-23 |
2004-07-08 |
Janssen Pharmaceutica N.V. |
Substituted 4-(4-piperidin-4-yl-piperazin-1-yl)-azepane derivatives and their use as neurokinin antagonists
|
|
US20040235855A1
(en)
|
2003-03-31 |
2004-11-25 |
Bharat Lagu |
Phospholipase C inhibitors for use in treating inflammatory disorders
|
|
DE602004013772D1
(de)
|
2003-06-10 |
2008-06-26 |
Janssen Pharmaceutica Nv |
Kombination von opioiden und einem piperazin-derivat für die behandlung von schmerzen
|
|
EP1633737A1
(en)
|
2003-06-13 |
2006-03-15 |
Schering Aktiengesellschaft |
Quinolyl amide derivatives as ccr-5 antagonists
|
|
MXPA05013596A
(es)
|
2003-06-30 |
2006-03-09 |
Schering Corp |
Antagonistas de hormona concentradora de melanina para el tratamiento de obesidad.
|
|
CN1898231B
(zh)
|
2003-11-03 |
2010-10-27 |
先灵公司 |
用作趋化因子受体抑制剂的双六氢吡啶衍生物
|
|
BRPI0417605B8
(pt)
|
2003-12-18 |
2021-05-25 |
Incyte Corp |
n-[2-((3s)-3-{[4-hidróxi-4-(5-pirimidin-2- ilpiridin-2-il)ciclohexil]amino}-pirrolidin-1-il)-2- oxoetil]-3-(trifluor-metil)benzamida, ou um sal farmaceuticamente aceitável do mesmo e composição que o compreende.
|
|
BRPI0509803A
(pt)
|
2004-04-13 |
2007-09-18 |
Incyte Corp |
derivados de piperazinilpiperidina como antagonistas de receptor de quimiocina
|
|
JP2007537264A
(ja)
|
2004-05-11 |
2007-12-20 |
インサイト コーポレイション |
ケモカインレセプタのモジュレータとしての3−(4−ヘテロアリールシクロヘキシルアミノ)シクロペンタンカルボキサミド
|
|
JP4116670B2
(ja)
|
2004-06-28 |
2008-07-09 |
インサイト コーポレイション |
ケモカイン受容体の調節剤としての3−アミノシクロペンタンカルボキサミド
|
|
WO2006004741A2
(en)
|
2004-06-28 |
2006-01-12 |
Incyte Corporation |
3-aminocyclopentanecarboxamides as modulators of chemokine receptors
|
|
US7880002B2
(en)
|
2004-12-29 |
2011-02-01 |
Millennium Pharmaceuticals, Inc. |
Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists
|
|
US7635698B2
(en)
|
2004-12-29 |
2009-12-22 |
Millennium Pharmaceuticals, Inc. |
Compounds useful as chemokine receptor antagonists
|
|
US7728135B2
(en)
|
2005-01-06 |
2010-06-01 |
Schering Corporation |
Synthesis of CCR5 receptor antagonists
|
|
MX2007009949A
(es)
|
2005-02-16 |
2007-09-26 |
Schering Corp |
Pirazinil-piperazin-piperidinas sustituidas con heteroarilo con actividad antagonista de cxcr3.
|
|
CA2598456A1
(en)
|
2005-02-16 |
2006-08-24 |
Schering Corporation |
Heterocyclic substituted piperazines with cxcr3 antagonist activity
|
|
EP1853583B1
(en)
|
2005-02-16 |
2011-09-07 |
Schering Corporation |
Amine-linked pyridyl and phenyl substituted piperazine-piperidines with cxcr3 antagonist activity
|
|
BRPI0607946A2
(pt)
|
2005-02-16 |
2009-10-20 |
Schering Corp |
piperazina-piperidinas substituìdas por pirazinila com atividade de antagonista cxcr3
|
|
CA2598489A1
(en)
|
2005-02-16 |
2006-08-24 |
Schering Corporation |
Piperazine-piperidines with cxcr3 antagonist activity
|
|
AU2006214378A1
(en)
|
2005-02-16 |
2006-08-24 |
Pharmacopeia, Inc. |
Pyridyl and phenyl substituted piperazine-piperidines with CXCR3 antagonist activity
|
|
CN101146793A
(zh)
|
2005-02-16 |
2008-03-19 |
先灵公司 |
具有cxcr3拮抗剂活性的新的杂环取代了的吡啶或苯基化合物
|
|
EP1858886A1
(en)
|
2005-02-23 |
2007-11-28 |
Schering Corporation |
Piperidinyl piperidine derivatives useful as inhibitors of chemokine receptors
|
|
JP4769257B2
(ja)
|
2005-02-23 |
2011-09-07 |
シェーリング コーポレイション |
ケモカインレセプターのインヒビターとして有用なピペリジニルピペラジン誘導体
|
|
MEP1008A
(xx)
|
2005-12-21 |
2010-02-10 |
Incyte Corp |
3-aminociklopentankarboksamidi kao modulatori receptora hemokina
|
|
TW200745087A
(en)
|
2006-02-24 |
2007-12-16 |
Schering Corp |
CCR5 antagonists useful for treating HIV
|
|
US20080108586A1
(en)
|
2006-09-06 |
2008-05-08 |
Incyte Corporation |
Combination therapy for human immunodeficiency virus infection
|