|
WO1998052558A1
(en)
*
|
1997-05-23 |
1998-11-26 |
Bayer Corporation |
INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS
|
|
EP1473292A1
(en)
*
|
1997-11-03 |
2004-11-03 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as anti-inflammatory agents
|
|
AU2006201959B2
(en)
*
|
1997-12-22 |
2008-09-04 |
Bayer Healthcare Llc |
Inhibition of Raf Kinase using Substituted Heterocyclic Ureas
|
|
SK286213B6
(sk)
*
|
1997-12-22 |
2008-05-06 |
Bayer Corporation |
Substituované heterocyklické močoviny, farmaceutický prípravok ich obsahujúci a ich použitie
|
|
US7329670B1
(en)
|
1997-12-22 |
2008-02-12 |
Bayer Pharmaceuticals Corporation |
Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
|
|
US7517880B2
(en)
|
1997-12-22 |
2009-04-14 |
Bayer Pharmaceuticals Corporation |
Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
|
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
US20020065296A1
(en)
*
|
1999-01-13 |
2002-05-30 |
Bayer Corporation |
Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
|
|
ATE538794T1
(de)
|
1999-01-13 |
2012-01-15 |
Bayer Healthcare Llc |
Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
|
|
EP1690853B1
(en)
*
|
1999-01-13 |
2010-03-10 |
Bayer HealthCare LLC |
Use of omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
WO2000042012A1
(en)
*
|
1999-01-13 |
2000-07-20 |
Bayer Corporation |
φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
|
|
US7351834B1
(en)
|
1999-01-13 |
2008-04-01 |
Bayer Pharmaceuticals Corporation |
ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
UA73492C2
(en)
*
|
1999-01-19 |
2005-08-15 |
|
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
MXPA01008440A
(es)
|
1999-02-22 |
2002-04-24 |
Boehringer Ingelheim Pharma |
Derivados heterociclicos policiclos como agentes anti-inflamatorios..
|
|
WO2000055152A1
(en)
*
|
1999-03-12 |
2000-09-21 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as anti-inflammatory agents
|
|
NZ528846A
(en)
|
1999-03-12 |
2005-05-27 |
Boehringer Ingelheim Pharma |
Compounds useful as anti-inflammatory agents
|
|
ATE312823T1
(de)
|
1999-07-09 |
2005-12-15 |
Boehringer Ingelheim Pharma |
Verfahren zur herstellung heteroarylsubstituierter ureaverbindungen
|
|
KR20020060160A
(ko)
|
1999-08-12 |
2002-07-16 |
파마시아 이탈리아 에스.피.에이. |
3(5)-아미노-피라졸 유도체, 이의 제조 방법 및항종양제로서의 이의 용도
|
|
US6387900B1
(en)
|
1999-08-12 |
2002-05-14 |
Pharmacia & Upjohn S.P.A. |
3(5)-ureido-pyrazole derivatives process for their preparation and their use as antitumor agents
|
|
WO2001036403A1
(en)
*
|
1999-11-16 |
2001-05-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Urea derivatives as anti-inflammatory agents
|
|
SE9904177D0
(sv)
*
|
1999-11-18 |
1999-11-18 |
Astra Ab |
Novel compounds
|
|
US6525046B1
(en)
|
2000-01-18 |
2003-02-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
US6608052B2
(en)
|
2000-02-16 |
2003-08-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compounds useful as anti-inflammatory agents
|
|
GB0010757D0
(en)
|
2000-05-05 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0016787D0
(en)
|
2000-07-07 |
2000-08-30 |
Pfizer Ltd |
Compounds useful in therapy
|
|
FR2812633A1
(fr)
*
|
2000-08-04 |
2002-02-08 |
Aventis Cropscience Sa |
Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides
|
|
US6645990B2
(en)
|
2000-08-15 |
2003-11-11 |
Amgen Inc. |
Thiazolyl urea compounds and methods of uses
|
|
FR2815030A1
(fr)
*
|
2000-10-05 |
2002-04-12 |
Lipha |
Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant et leur utilisation pour la preparation de medicaments
|
|
DE60137273D1
(de)
|
2000-10-20 |
2009-02-12 |
Eisai R&D Man Co Ltd |
Verfahren zur Herstellung von 4-Phenoxy chinolin Derivaten
|
|
AU2002232439A1
(en)
|
2000-11-29 |
2002-06-11 |
Glaxo Group Limited |
Benzimidazole derivatives useful as tie-2 and/or vegfr-2 inhibitors
|
|
US6946476B2
(en)
|
2000-12-21 |
2005-09-20 |
Schering Corporation |
Heteroaryl urea neuropeptide Y Y5 receptor antagonists
|
|
NZ526174A
(en)
*
|
2000-12-21 |
2004-12-24 |
Schering Corp |
Heteroaryl urea neuropeptide Y Y5 receptor antagonists
|
|
US7235576B1
(en)
|
2001-01-12 |
2007-06-26 |
Bayer Pharmaceuticals Corporation |
Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
US7371763B2
(en)
|
2001-04-20 |
2008-05-13 |
Bayer Pharmaceuticals Corporation |
Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
|
|
EP1652847B1
(en)
*
|
2001-04-27 |
2008-05-28 |
Kirin Pharma Kabushiki Kaisha |
Quinoline and quinazoline derivatives for the treatment of tumors
|
|
WO2002092576A1
(en)
|
2001-05-16 |
2002-11-21 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Diarylurea derivatives useful as anti-inflammatory agents
|
|
EP1395561A1
(en)
|
2001-05-25 |
2004-03-10 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Carbamate and oxamide compounds as inhibitors of cytokine production
|
|
AU2002310156A1
(en)
|
2001-06-05 |
2002-12-16 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
1,4-disubstituted benzo-fused cycloalkyl urea compounds
|
|
JP2004536845A
(ja)
|
2001-07-11 |
2004-12-09 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
サイトカイン媒介疾患の治療方法
|
|
JP4825375B2
(ja)
*
|
2001-08-28 |
2011-11-30 |
株式会社 資生堂 |
ジチアゾール化合物及びマトリックスメタロプロテアーゼ活性阻害剤、皮膚外用剤
|
|
GB0121941D0
(en)
|
2001-09-11 |
2001-10-31 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2003028720A1
(en)
|
2001-09-26 |
2003-04-10 |
Pharmacia Italia S.P.A. |
Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
|
|
EP1438048A1
(en)
|
2001-10-18 |
2004-07-21 |
Boehringer Ingelheim Pharmaceuticals Inc. |
1,4-disubstituted benzo-fused urea compounds as cytokine inhibitors
|
|
MXPA04007832A
(es)
|
2002-02-11 |
2005-09-08 |
Bayer Pharmaceuticals Corp |
Aril-ureas con actividad inhibitoria de angiogenesis.
|
|
US20040023961A1
(en)
*
|
2002-02-11 |
2004-02-05 |
Bayer Corporation |
Aryl ureas with raf kinase and angiogenisis inhibiting activity
|
|
MXPA04007830A
(es)
*
|
2002-02-11 |
2005-07-01 |
Bayer Pharmaceuticals Corp |
Arilureas como inhibidores de cinasa.
|
|
US10653684B2
(en)
|
2002-02-11 |
2020-05-19 |
Bayer Healthcare Llc |
Aryl ureas with angiogenisis inhibiting activity
|
|
ATE386030T1
(de)
|
2002-02-25 |
2008-03-15 |
Boehringer Ingelheim Pharma |
1,4-disubstituierte benzokondensierte cycloalkyl- harnstoffverbindungen zur behandlung von zytokinvermittelten erkrankungen
|
|
JP4751063B2
(ja)
*
|
2002-05-17 |
2011-08-17 |
ファイザー イタリア ソシエタ ア レスポンサビリタ リミタータ |
キナーゼ阻害剤として活性のアミノインダゾール誘導体、それらの調製方法、及びそれらを含む薬学的組成物
|
|
BR0312023A
(pt)
|
2002-06-27 |
2005-03-22 |
Novo Nordisk As |
Composto, composto ativador da glicose cinase, método para evitar a hipoglicemia, uso de um composto, e, composição farmacêutica
|
|
RU2340605C2
(ru)
|
2002-06-27 |
2008-12-10 |
Ново Нордиск А/С |
Арилкарбонильные производные в качестве терапевтических средств
|
|
DE60310730T2
(de)
|
2002-07-09 |
2007-05-16 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Pharmazeutische zusammensetzungen aus anticholinergica und p38 kinase hemmern zur behandlung von erkrankungen der atemwege
|
|
MXPA05002493A
(es)
*
|
2002-09-05 |
2005-05-27 |
Neurosearch As |
Derivados de diarilurea y su uso como bloqueadores del canal del cloro.
|
|
US7202257B2
(en)
|
2003-12-24 |
2007-04-10 |
Deciphera Pharmaceuticals, Llc |
Anti-inflammatory medicaments
|
|
US7144911B2
(en)
|
2002-12-31 |
2006-12-05 |
Deciphera Pharmaceuticals Llc |
Anti-inflammatory medicaments
|
|
CA2511970C
(en)
*
|
2003-01-14 |
2012-06-26 |
Cytokinetics, Inc. |
Urea derivatives useful in the treatment of heart failure
|
|
EP1603879A2
(en)
*
|
2003-02-28 |
2005-12-14 |
Bayer Pharmaceuticals Corporation |
Substituted pyridine derivatives useful in the treatment of cancer and other disorders
|
|
EP1608639A2
(en)
|
2003-02-28 |
2005-12-28 |
Bayer Pharmaceuticals Corporation |
Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders
|
|
WO2004085433A2
(en)
*
|
2003-03-28 |
2004-10-07 |
Pharmacia & Upjohn Company Llc |
Positive allosteric modulators of the nicotinic acetylcholine receptor
|
|
WO2004113274A2
(en)
|
2003-05-20 |
2004-12-29 |
Bayer Pharmaceuticals Corporation |
Diaryl ureas with kinase inhibiting activity
|
|
EA010485B1
(ru)
|
2003-07-23 |
2008-10-30 |
Байер Фамэсьютиклс Копэрейшн |
Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты)
|
|
US7683172B2
(en)
|
2003-11-11 |
2010-03-23 |
Eisai R&D Management Co., Ltd. |
Urea derivative and process for preparing the same
|
|
US20050192314A1
(en)
|
2003-11-13 |
2005-09-01 |
Ambit Biosciences Corporation |
Urea derivatives as C-kit modulators
|
|
GB0330043D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
|
|
GB0330042D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions them
|
|
JP4834840B2
(ja)
|
2004-01-06 |
2011-12-14 |
ノヴォ ノルディスク アー／エス |
ヘテロアリール尿素およびグルコキナーゼ活性化剤としてのその使用
|
|
US20070161677A1
(en)
*
|
2004-01-30 |
2007-07-12 |
Merck Patent Gmbh |
Bisarylurea derivatives
|
|
TW200530236A
(en)
|
2004-02-23 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Heteroaryl phenylurea
|
|
US20060211752A1
(en)
|
2004-03-16 |
2006-09-21 |
Kohn Leonard D |
Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
|
|
CN101010315A
(zh)
|
2004-04-30 |
2007-08-01 |
拜耳制药公司 |
用于治疗癌症的取代的吡唑基脲衍生物
|
|
JP5080970B2
(ja)
|
2004-06-17 |
2012-11-21 |
サイトキネティクス・インコーポレーテッド |
心疾患を治療するための置換尿素誘導体
|
|
EP1609789A1
(en)
*
|
2004-06-23 |
2005-12-28 |
Eli Lilly And Company |
Ureido-pyrazole derivatives and their use as kinase inhibitors
|
|
US20060035893A1
(en)
|
2004-08-07 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
|
|
AU2005283422C1
(en)
|
2004-09-17 |
2017-02-02 |
Eisai R & D Management Co., Ltd. |
Medicinal composition
|
|
EP1824843A2
(en)
|
2004-12-07 |
2007-08-29 |
Locus Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
|
JP2008523071A
(ja)
|
2004-12-07 |
2008-07-03 |
ルーカス ファーマシューティカルズ， インコーポレイテッド |
Ｍａｐキナーゼの尿素インヒビター
|
|
PE20060777A1
(es)
|
2004-12-24 |
2006-10-06 |
Boehringer Ingelheim Int |
Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
|
|
SG160364A1
(en)
|
2005-03-07 |
2010-04-29 |
Bayer Schering Pharma Ag |
Pharmaceutical composition comprising an omega-carboxyaryl substituted diphenyl urea for the treatment of cancer
|
|
DE102005015253A1
(de)
|
2005-04-04 |
2006-10-05 |
Merck Patent Gmbh |
Pyrazolderivate
|
|
WO2007015578A1
(ja)
|
2005-08-02 |
2007-02-08 |
Eisai R & D Management Co., Ltd. |
血管新生阻害物質の効果を検定する方法
|
|
US7538223B2
(en)
|
2005-08-04 |
2009-05-26 |
Cytokinetics, Inc. |
Compounds, compositions and methods
|
|
DE102005037499A1
(de)
*
|
2005-08-09 |
2007-02-15 |
Merck Patent Gmbh |
Pyrazolderivate
|
|
AU2006313701B2
(en)
|
2005-11-11 |
2012-05-31 |
Aeterna Zentaris Gmbh |
Novel pyridopyrazines and their use as modulators of kinases
|
|
EP1790342A1
(de)
|
2005-11-11 |
2007-05-30 |
Zentaris GmbH |
Pyridopyrazin-Derivate und deren Verwendung als Modulatoren der Signaltransduktionswege
|
|
US8217042B2
(en)
|
2005-11-11 |
2012-07-10 |
Zentaris Gmbh |
Pyridopyrazines and their use as modulators of kinases
|
|
US7825120B2
(en)
|
2005-12-15 |
2010-11-02 |
Cytokinetics, Inc. |
Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas
|
|
TW200808321A
(en)
|
2005-12-15 |
2008-02-16 |
Cytokinetics Inc |
Certain chemical entities, compositions and methods
|
|
EP1959962A2
(en)
|
2005-12-16 |
2008-08-27 |
Cytokinetics, Inc. |
Certain chemical entities, compositions, and methods
|
|
EP1962852B1
(en)
|
2005-12-19 |
2017-01-25 |
Cytokinetics, Inc. |
Compounds, compositions and methods
|
|
US8580798B2
(en)
|
2005-12-21 |
2013-11-12 |
Bayer Intellectual Property Gmbh |
Substituted pyrimidine derivatives useful in the treatment of cancer and other disorders
|
|
WO2007076460A2
(en)
*
|
2005-12-23 |
2007-07-05 |
Kalypsys, Inc. |
Substituted thiazole ureas useful as inhibitors of protein kinases
|
|
RU2448708C3
(ru)
|
2006-05-18 |
2017-09-28 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Противоопухолевое средство против рака щитовидной железы
|
|
US20080045589A1
(en)
|
2006-05-26 |
2008-02-21 |
Susan Kelley |
Drug Combinations with Substituted Diaryl Ureas for the Treatment of Cancer
|
|
DE102006029795A1
(de)
*
|
2006-06-27 |
2008-01-03 |
Schebo Biotech Ag |
Neue Harnstoff-Derivate und deren Verwendungen
|
|
CN101511793B
(zh)
|
2006-08-28 |
2011-08-03 |
卫材R&D管理有限公司 |
针对未分化型胃癌的抗肿瘤剂
|
|
US7897762B2
(en)
|
2006-09-14 |
2011-03-01 |
Deciphera Pharmaceuticals, Llc |
Kinase inhibitors useful for the treatment of proliferative diseases
|
|
JP2010514692A
(ja)
|
2006-12-20 |
2010-05-06 |
バイエル ヘルスケア リミティド ライアビリティ カンパニー |
癌の治療に有用なヒドロキシメチルフェニルピラゾリル尿素化合物
|
|
CN101600694A
(zh)
|
2007-01-29 |
2009-12-09 |
卫材R&D管理有限公司 |
未分化型胃癌治疗用组合物
|
|
CN101636397B
(zh)
*
|
2007-04-13 |
2012-06-13 |
中国人民解放军军事医学科学院毒物药物研究所 |
脲类化合物、其制备方法及其医药用途
|
|
KR20100014811A
(ko)
|
2007-04-20 |
2010-02-11 |
데시페라 파마슈티칼스, 엘엘씨. |
골수증식성 질환 및 기타 증식성 질환의 치료에 유용한 키나제 억제제
|
|
EP1992344A1
(en)
|
2007-05-18 |
2008-11-19 |
Institut Curie |
P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
|
|
KR101513326B1
(ko)
|
2007-11-09 |
2015-04-17 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
혈관 신생 저해 물질과 항종양성 백금 착물의 병용
|
|
GB0818033D0
(en)
|
2008-10-02 |
2008-11-05 |
Respivert Ltd |
Novel compound
|
|
MY159230A
(en)
*
|
2008-10-02 |
2016-12-30 |
Respivert Ltd |
P38 map kinase inhibitors
|
|
JP5670912B2
(ja)
|
2008-12-11 |
2015-02-18 |
レスピバート・リミテツド |
ｐ３８ＭＡＰキナーゼ阻害剤
|
|
GB0905955D0
(en)
|
2009-04-06 |
2009-05-20 |
Respivert Ltd |
Novel compounds
|
|
DK2468281T3
(en)
|
2009-08-19 |
2016-03-21 |
Eisai R&D Man Co Ltd |
Quinolinderivatholdig pharmaceutical composition
|
|
JP2013502429A
(ja)
*
|
2009-08-19 |
2013-01-24 |
アムビト ビオスシエンセス コルポラチオン |
ビアリール化合物及びその使用方法
|
|
WO2011162343A1
(ja)
|
2010-06-25 |
2011-12-29 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
キナーゼ阻害作用を有する化合物の併用による抗腫瘍剤
|
|
CA2805874A1
(en)
|
2010-07-19 |
2012-01-26 |
Bayer Healthcare Llc |
Drug combinations with fluoro-substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
|
|
EP2508184A1
(en)
|
2011-04-06 |
2012-10-10 |
Æterna Zentaris GmbH |
Pyridopyrazine derivatives and their use
|
|
CN103402519B
(zh)
|
2011-04-18 |
2015-11-25 |
卫材R&D管理有限公司 |
肿瘤治疗剂
|
|
JP6038128B2
(ja)
|
2011-06-03 |
2016-12-07 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
レンバチニブ化合物に対する甲状腺癌対象及び腎臓癌対象の反応性を予測及び評価するためのバイオマーカー
|
|
CN103172648B
(zh)
*
|
2011-12-20 |
2016-05-25 |
上海迪诺医药科技有限公司 |
三杂环衍生物、制备方法及应用
|
|
EP2799537B1
(en)
|
2011-12-28 |
2021-09-22 |
Kyoto Prefectural Public University Corporation |
Normalization of culture of corneal endothelial cells
|
|
US8461179B1
(en)
|
2012-06-07 |
2013-06-11 |
Deciphera Pharmaceuticals, Llc |
Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
|
|
US20150225373A1
(en)
|
2012-08-29 |
2015-08-13 |
Respivert Limited |
Kinase inhibitors
|
|
MY178262A
(en)
|
2012-11-13 |
2020-10-07 |
Array Biopharma Inc |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
|
HRP20161613T1
(hr)
|
2012-11-13 |
2017-01-13 |
Array Biopharma, Inc. |
Tvari bicikličke ureje, tioureje, gvanidina i cijanogvanidina korisne za liječenje boli
|
|
AU2013364953A1
(en)
|
2012-12-21 |
2015-04-30 |
Eisai R&D Management Co., Ltd. |
Amorphous form of quinoline derivative, and method for producing same
|
|
MX362181B
(es)
|
2013-02-19 |
2019-01-08 |
Ono Pharmaceutical Co |
Compuesto inhibidor de cinasa del receptor de tropomiosina (trk).
|
|
EP2997377B1
(en)
|
2013-05-14 |
2018-07-18 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
|
US9750723B2
(en)
|
2013-10-31 |
2017-09-05 |
Ohio University |
Prevention and treatment of non-alcoholic fatty liver disease
|
|
WO2015072580A1
(ja)
|
2013-11-14 |
2015-05-21 |
学校法人同志社 |
細胞増殖促進または細胞障害抑制による角膜内皮治療薬
|
|
CA2949160C
(en)
|
2014-05-15 |
2023-03-21 |
Array Biopharma Inc. |
1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor
|
|
WO2016010609A1
(en)
|
2014-07-18 |
2016-01-21 |
Ohio University |
Prevention and treatment of non-alcoholic fatty liver disease
|
|
CA2957785C
(en)
|
2014-08-11 |
2023-01-03 |
Angion Biomedica Corporation |
Cytochrome p450 inhibitors and uses thereof
|
|
PT3524595T
(pt)
|
2014-08-28 |
2022-09-19 |
Eisai R&D Man Co Ltd |
Derivado de quinolina altamente puro e método para produção do mesmo
|
|
PE20170705A1
(es)
|
2014-09-10 |
2017-05-21 |
Glaxosmithkline Ip Dev Ltd |
Nuevos compuestos como inhibidores de ret (reorganizado durante la transfeccion)
|
|
EA032030B1
(ru)
|
2014-09-10 |
2019-03-29 |
Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед |
Соединения в качестве ингибиторов реаранжированной во время трансфекции (ret) киназы
|
|
US9638690B2
(en)
|
2014-11-07 |
2017-05-02 |
The University Of British Columbia |
Compounds and compositions for use as alkylating agent sensors and methods of use thereof
|
|
JP2018501279A
(ja)
|
2014-12-31 |
2018-01-18 |
アンギオン バイオメディカ コーポレイション |
疾患を治療するための方法及び薬剤
|
|
AU2016224583B2
(en)
|
2015-02-25 |
2021-06-03 |
Eisai R&D Management Co., Ltd. |
Method for suppressing bitterness of quinoline derivative
|
|
KR102662228B1
(ko)
|
2015-03-04 |
2024-05-02 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
|
BR112017027227B1
(pt)
|
2015-06-16 |
2023-12-12 |
Eisai R&D Management Co., Ltd |
Agente anti-câncer
|
|
JP6553726B2
(ja)
|
2015-08-20 |
2019-07-31 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
腫瘍治療剤
|
|
JP6581320B2
(ja)
|
2017-02-08 |
2019-09-25 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
腫瘍治療用医薬組成物
|
|
EP3624800A4
(en)
|
2017-05-16 |
2021-02-17 |
Eisai R&D Management Co., Ltd. |
TREATMENT OF HEPATOCELLULAR CARCINOMA
|
|
IL276398B2
(en)
|
2018-01-31 |
2026-03-01 |
Deciphera Pharmaceuticals Llc |
Combination therapy for mastocytosis
|
|
KR102708177B1
(ko)
|
2018-01-31 |
2024-09-23 |
데시페라 파마슈티칼스, 엘엘씨. |
위장관 기질 종양의 치료를 위한 병용 요법
|
|
CN112040945A
(zh)
|
2018-06-12 |
2020-12-04 |
Vtv治疗有限责任公司 |
葡萄糖激酶激活剂与胰岛素或胰岛素类似物组合的治疗用途
|
|
EP3938363A1
(en)
|
2019-03-11 |
2022-01-19 |
Teva Pharmaceuticals International GmbH |
Solid state forms of ripretinib
|
|
LT4013412T
(lt)
|
2019-08-12 |
2026-03-25 |
Deciphera Pharmaceuticals, Llc |
Ripretinibas, skirtas virškinamojo trakto stromos navikų gydymui
|
|
PT4013412T
(pt)
|
2019-08-12 |
2026-03-18 |
Deciphera Pharmaceuticals Llc |
Ripretinib para o tratamento de tumores estromais gastrointestinais
|
|
HRP20231699T1
(hr)
|
2019-12-30 |
2024-05-10 |
Deciphera Pharmaceuticals, Llc |
Formulacije inhibitora amorfne kinaze i postupci njihove primjene
|
|
CN115243681B
(zh)
|
2019-12-30 |
2024-08-16 |
德西费拉制药有限责任公司 |
1-(4-溴-5-(1-乙基-7-(甲氨基)-2-侧氧基-1,2-二氢-1,6-萘啶-3-基)-2-氟苯基)-3-苯基脲的组合物
|
|
US12391658B2
(en)
|
2020-02-18 |
2025-08-19 |
Vtv Therapeutics Llc |
Sulfoxide and sulfone glucokinase activators and methods of use thereof
|
|
CN116102522A
(zh)
*
|
2021-11-09 |
2023-05-12 |
河南省化工研究所有限责任公司 |
一种阳离子蓝染料中间体的制备方法
|
|
US11779572B1
(en)
|
2022-09-02 |
2023-10-10 |
Deciphera Pharmaceuticals, Llc |
Methods of treating gastrointestinal stromal tumors
|