JP2005527625A5 - - Google Patents
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- Publication number
- JP2005527625A5 JP2005527625A5 JP2004507434A JP2004507434A JP2005527625A5 JP 2005527625 A5 JP2005527625 A5 JP 2005527625A5 JP 2004507434 A JP2004507434 A JP 2004507434A JP 2004507434 A JP2004507434 A JP 2004507434A JP 2005527625 A5 JP2005527625 A5 JP 2005527625A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- phenyl
- methyl
- methyloxy
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*(C)(C(*)*)C(*)(*)c1cccc(*)c1 Chemical compound C*(C)(C(*)*)C(*)(*)c1cccc(*)c1 0.000 description 5
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38305002P | 2002-05-23 | 2002-05-23 | |
| US44106503P | 2003-01-17 | 2003-01-17 | |
| US10/444,946 US6908935B2 (en) | 2002-05-23 | 2003-05-22 | Calcium receptor modulating agents |
| PCT/US2003/016401 WO2003099776A1 (en) | 2002-05-23 | 2003-05-23 | Calcium receptor modulating arylalkylamines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010027494A Division JP2010150268A (ja) | 2002-05-23 | 2010-02-10 | カルシウム受容体調節剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005527625A JP2005527625A (ja) | 2005-09-15 |
| JP2005527625A5 true JP2005527625A5 (https=) | 2006-07-06 |
| JP4486882B2 JP4486882B2 (ja) | 2010-06-23 |
Family
ID=29587692
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004507434A Expired - Fee Related JP4486882B2 (ja) | 2002-05-23 | 2003-05-23 | カルシウム受容体調節アリールアルキルアミン |
| JP2010027494A Pending JP2010150268A (ja) | 2002-05-23 | 2010-02-10 | カルシウム受容体調節剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010027494A Pending JP2010150268A (ja) | 2002-05-23 | 2010-02-10 | カルシウム受容体調節剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6908935B2 (https=) |
| EP (1) | EP1509497A1 (https=) |
| JP (2) | JP4486882B2 (https=) |
| AU (1) | AU2003233671B2 (https=) |
| CA (1) | CA2486399C (https=) |
| MX (1) | MXPA04011471A (https=) |
| PL (1) | PL376438A1 (https=) |
| WO (1) | WO2003099776A1 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6908935B2 (en) * | 2002-05-23 | 2005-06-21 | Amgen Inc. | Calcium receptor modulating agents |
| EP2295433A3 (en) * | 2003-03-06 | 2011-07-06 | Eisai R&D Management Co., Ltd. | JNK inhibitors |
| EP2174932B1 (en) * | 2003-03-13 | 2019-07-03 | Idemitsu Kosan Co., Ltd. | Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same |
| WO2005065050A2 (ja) * | 2003-12-25 | 2005-07-21 | Asahi Kasei Pharma Corporation | 2環化合物 |
| GB0400781D0 (en) * | 2004-01-14 | 2004-02-18 | Novartis Ag | Organic compounds |
| HRP20100040T1 (hr) * | 2004-03-02 | 2010-02-28 | Aventis Pharmaceuticals Inc. | Postupak dobivanja inhibitora triptaze |
| ES2561111T3 (es) | 2004-05-28 | 2016-02-24 | Mitsubishi Tanabe Pharma Corporation | Arilalquilaminas y procedimiento para la producción de las mismas |
| US7361789B1 (en) | 2004-07-28 | 2008-04-22 | Amgen Inc. | Dihydronaphthalene compounds, compositions, uses thereof, and methods for synthesis |
| AU2006227429A1 (en) * | 2005-03-17 | 2006-09-28 | Amgen Inc. | Methods of decreasing calcification |
| US7585886B2 (en) | 2005-05-19 | 2009-09-08 | Astellas Pharma Inc. | Pyrrolidine derivative or salt thereof |
| JP5388574B2 (ja) * | 2005-05-31 | 2014-01-15 | バーテックス ファーマシューティカルズ インコーポレイテッド | イオンチャネルのモジュレーターとして有用なヘテロ環式類 |
| AU2006295340B2 (en) | 2005-08-05 | 2010-11-11 | Amgen Inc. | Stable aqueous protein or antibody pharmaceutical formulations and their preparation |
| US8486381B2 (en) * | 2005-09-02 | 2013-07-16 | Amgen Inc. | Methods of modulating intestinal fluid balance |
| WO2007047969A2 (en) * | 2005-10-21 | 2007-04-26 | Amgen Inc. | Methods of decreasing vascular calcification using il-1 inhibitors |
| TW200806290A (en) * | 2006-01-25 | 2008-02-01 | Synta Pharmaceuticals Corp | Substituted biaryl compounds for inflammation and immune-related uses |
| MX2008012061A (es) * | 2006-03-23 | 2008-12-17 | Amgen Inc | Metodos y composiciones para elaborar y utilizar polimorfos de cinacalcet. |
| EP2010150A2 (en) * | 2006-04-20 | 2009-01-07 | Amgen Inc. | Stable emulsion formulations |
| GB0614579D0 (en) * | 2006-07-21 | 2006-08-30 | Black James Foundation | Pyrimidine derivatives |
| US20100222345A1 (en) * | 2006-08-09 | 2010-09-02 | Caroline Jean Diaz | Novel compounds as antagonists or inverse agonists for opioid receptors |
| TW200821276A (en) * | 2006-08-18 | 2008-05-16 | Leo Pharma As | Substituted acetylenic compounds useful for the treatment of diseases |
| MX2009003981A (es) * | 2006-10-26 | 2009-04-27 | Amgen Inc | Agentes moduladores del receptor de calcio. |
| CN101583593A (zh) * | 2006-11-13 | 2009-11-18 | 辉瑞产品公司 | 二芳基、二吡啶基和芳基-吡啶基衍生物及其用途 |
| TW200840566A (en) * | 2006-12-22 | 2008-10-16 | Esteve Labor Dr | Heterocyclyl-substituted-ethylamino-phenyl derivatives, their preparation and use as medicaments |
| CA2681582C (en) | 2007-03-30 | 2015-07-14 | Amgen Inc. | Methods of treating bowel disorders |
| ES2476391T3 (es) * | 2007-10-15 | 2014-07-14 | Amgen Inc. | Agentes moduladores de receptor de calcio |
| EP2278961A2 (en) * | 2008-03-28 | 2011-02-02 | Amgen, Inc | Calcimimetic compound for use in the treatment of epithelial injury |
| WO2010042642A1 (en) * | 2008-10-08 | 2010-04-15 | Amgen Inc. | Calcium receptor modulating agents |
| WO2010052448A2 (en) * | 2008-11-05 | 2010-05-14 | Ucb Pharma S.A. | Fused pyrazine derivatives as kinase inhibitors |
| WO2010104882A1 (en) | 2009-03-10 | 2010-09-16 | Amgen Inc. | Methods of modulating sperm motility |
| DE102009015697A1 (de) | 2009-03-31 | 2010-10-07 | Markus Dr. Heinrich | Verfahren zur Arylierung von ringsubstituierten Phenolen und Phenylethern |
| EP2435400A2 (en) | 2009-05-27 | 2012-04-04 | Leo Pharma A/S | Novel calcium sensing receptor modulating compounds and pharmaceutical use thereof |
| US8765676B2 (en) | 2009-05-27 | 2014-07-01 | Leo Pharma A/S | Calcium sensing receptor modulating compounds and pharmaceutical use thereof |
| WO2012000498A1 (en) | 2010-06-30 | 2012-01-05 | Leo Pharma A/S | New polymorphic form of a calcimimetic compound |
| JP5968881B2 (ja) | 2010-06-30 | 2016-08-10 | レオ ファーマ アクティーゼルスカブ | カルシウム模倣化合物の新規多形 |
| JP2014508103A (ja) | 2010-11-26 | 2014-04-03 | レオ ファーマ アクティーゼルスカブ | カルシウム感知受容体活性化合物 |
| WO2012069420A2 (en) | 2010-11-26 | 2012-05-31 | Leo Pharma A/S | Calcium-sensing receptor-active compounds |
| JP2014500882A (ja) | 2010-11-26 | 2014-01-16 | レオ ファーマ アクティーゼルスカブ | カルシウム感知受容体活性化合物 |
| EP2643292A1 (en) | 2010-11-26 | 2013-10-02 | Leo Pharma A/S | Calcium-sensing receptor-active compounds |
| SG193331A1 (en) * | 2011-03-18 | 2013-10-30 | Lupin Ltd | Benzo [b] [1, 4] oxazin derivatives as calcium sensing receptor modulators |
| JP2015528462A (ja) * | 2012-08-27 | 2015-09-28 | ルピン・リミテッドLupin Limited | カルシウム感知受容体モジュレーターとしてのアリールアルキルアミン化合物 |
| GB201217330D0 (en) | 2012-09-28 | 2012-11-14 | Univ Cardiff | Therapeutic for treating inflammatory lung disorders |
| CN104292157A (zh) * | 2014-09-15 | 2015-01-21 | 湖南华腾制药有限公司 | 一种1-(喹啉-4-基)乙胺的制备方法 |
| WO2017037616A1 (en) * | 2015-08-31 | 2017-03-09 | Lupin Limited | Arylalkylamine compounds as calcium sensing receptor modulators |
| DE102015011861B4 (de) | 2015-09-10 | 2018-03-01 | Rudolf Schindler | Neue cyclische Carboxamide als NMDA NR2B Rezeptor Inhibitoren |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT72878B (en) | 1980-04-24 | 1983-03-29 | Merck & Co Inc | Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents |
| US6011068A (en) | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6031003A (en) | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| ATE313321T1 (de) | 1991-08-23 | 2006-01-15 | Nps Pharma Inc | Kalzium-rezeptor aktive verbindungen |
| CN1192011C (zh) | 1991-08-23 | 2005-03-09 | Nps药物有限公司 | 对钙受体具活性的芳烷基胺化合物 |
| DE69333527T2 (de) | 1993-02-23 | 2005-06-16 | Brigham & Women's Hospital, Inc., Boston | Calciumrezeptoraktive moleküle |
| AU3414295A (en) | 1994-08-19 | 1996-03-14 | Nps Pharmaceuticals, Inc. | Methods and compounds active at metabotropic glutamate receptors useful for treatment of neurological disorders and diseases |
| WO1996009818A1 (en) | 1994-09-27 | 1996-04-04 | Merck & Co., Inc. | Endothelin receptor antagonists for the treatment of emesis |
| ES2285707T3 (es) | 1994-10-21 | 2007-11-16 | Nps Pharmaceuticals, Inc. | Compuestos activos frente al receptor de calcio. |
| US5585388A (en) | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
| ES2308779T3 (es) | 1995-07-26 | 2008-12-01 | Astrazeneca Ab | Receptores quimericos y metodos para identificar compuestos activos en los receptores de glutamato metabotropico y el uso de tales compuestos en el tratamiento de trastornos y enfermedades neurologicas. |
| DE69733649T2 (de) | 1996-04-09 | 2006-05-18 | NPS Pharmaceuticals, Inc., Salt Lake City | Calcylitische verbindungen |
| WO1997041090A1 (en) | 1996-05-01 | 1997-11-06 | Nps Pharmaceuticals, Inc. | Inorganic ion receptor-active compounds |
| CN1131202C (zh) | 1996-07-08 | 2003-12-17 | 麒麟麦酒株式会社 | 钙受体活性化合物 |
| AU735137B2 (en) | 1997-02-21 | 2001-07-05 | Bayer Intellectual Property Gmbh | Arylsulphonamides and analogues and their use for the treatment and neurovegetative disorders |
| UY24949A1 (es) | 1997-04-08 | 2001-04-30 | Smithkline Beecham Corp | Compuestos calcilíticos |
| AU8181098A (en) | 1997-07-03 | 1999-01-25 | Du Pont Pharmaceuticals Company | Aryl-and arylamino-substituted heterocycles as corticotropin releasing hormone antagonists |
| US6096745A (en) | 1998-03-25 | 2000-08-01 | Bristol-Myers Squibb Co. | Imidazolone anorectic agents: III. heteroaryl derivatives |
| CA2340341A1 (en) | 1998-08-12 | 2000-02-24 | Smithkline Beecham Corporation | Calcilytic compounds |
| CA2347092A1 (en) | 1998-10-14 | 2000-04-20 | Ortho-Mcneil Pharmaceutical, Inc. | 1,2-disubstituted cyclopropanes |
| TR200102490T2 (tr) | 1999-02-24 | 2001-12-21 | F.Hoffmann-La Roche Ag | Fenil ve piridinil türevleri |
| KR100437587B1 (ko) | 1999-02-24 | 2004-06-30 | 에프. 호프만-라 로슈 아게 | 3-페닐피리딘 유도체 및 그의 뉴로키닌-1 수용체길항제로서의 용도 |
| DE60036758T2 (de) | 1999-08-04 | 2008-07-24 | Sumitomo Chemical Co., Ltd. | Verfahren zur Herstellung von optisch aktiver 3,3,3-Trifluor-2-hydroxy-2-methylpropionsäure und deren Salze |
| DE10028575A1 (de) | 2000-06-14 | 2002-03-14 | Basf Ag | Integrinliganden |
| FR2800735B1 (fr) | 1999-11-09 | 2002-02-01 | Centre Nat Rech Scient | Nouvelles aralkyle-1,2-diamines possedant une activite calcimimetique et leur mode de preparation |
| EP1116711B1 (de) | 1999-12-18 | 2005-12-14 | Wella Aktiengesellschaft | 2-Aminoalkyl-1,4-diaminobenzol-Derivate und diese Verbindungen enthaltende Färbemittel |
| FR2809396B1 (fr) | 2000-05-24 | 2005-10-14 | Centre Nat Rech Scient | Nouvelles molecules possedant une activite calcimimetique et leur mode de preparation |
| DE10028402A1 (de) | 2000-06-13 | 2001-12-20 | Merck Patent Gmbh | Pyridin-2-yl-aminoalkycarbonylglycyl-beta-alanin und Derivate |
| AU2001269821A1 (en) | 2000-06-15 | 2001-12-24 | Barbara Chen | Cycloalkyl alkanoic acids as integrin receptor antagonists |
| JPWO2003020723A1 (ja) | 2001-08-30 | 2004-12-16 | 協和醗酵工業株式会社 | [1,2,4]トリアゾロ[1,5−a]ピリミジン誘導体 |
| US7176322B2 (en) * | 2002-05-23 | 2007-02-13 | Amgen Inc. | Calcium receptor modulating agents |
| US6908935B2 (en) * | 2002-05-23 | 2005-06-21 | Amgen Inc. | Calcium receptor modulating agents |
-
2003
- 2003-05-22 US US10/444,946 patent/US6908935B2/en not_active Expired - Lifetime
- 2003-05-23 CA CA2486399A patent/CA2486399C/en not_active Expired - Fee Related
- 2003-05-23 JP JP2004507434A patent/JP4486882B2/ja not_active Expired - Fee Related
- 2003-05-23 WO PCT/US2003/016401 patent/WO2003099776A1/en not_active Ceased
- 2003-05-23 PL PL03376438A patent/PL376438A1/xx unknown
- 2003-05-23 MX MXPA04011471A patent/MXPA04011471A/es active IP Right Grant
- 2003-05-23 AU AU2003233671A patent/AU2003233671B2/en not_active Ceased
- 2003-05-23 EP EP03729111A patent/EP1509497A1/en not_active Withdrawn
-
2005
- 2005-02-18 US US11/061,084 patent/US7196102B2/en not_active Expired - Fee Related
-
2007
- 2007-01-30 US US11/700,336 patent/US7524873B2/en not_active Expired - Fee Related
-
2010
- 2010-02-10 JP JP2010027494A patent/JP2010150268A/ja active Pending
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