JP2005527625A5 - - Google Patents
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- Publication number
- JP2005527625A5 JP2005527625A5 JP2004507434A JP2004507434A JP2005527625A5 JP 2005527625 A5 JP2005527625 A5 JP 2005527625A5 JP 2004507434 A JP2004507434 A JP 2004507434A JP 2004507434 A JP2004507434 A JP 2004507434A JP 2005527625 A5 JP2005527625 A5 JP 2005527625A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- phenyl
- methyl
- methyloxy
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*(C)(C(*)*)C(*)(*)c1cccc(*)c1 Chemical compound C*(C)(C(*)*)C(*)(*)c1cccc(*)c1 0.000 description 5
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38305002P | 2002-05-23 | 2002-05-23 | |
| US44106503P | 2003-01-17 | 2003-01-17 | |
| US10/444,946 US6908935B2 (en) | 2002-05-23 | 2003-05-22 | Calcium receptor modulating agents |
| PCT/US2003/016401 WO2003099776A1 (en) | 2002-05-23 | 2003-05-23 | Calcium receptor modulating arylalkylamines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010027494A Division JP2010150268A (ja) | 2002-05-23 | 2010-02-10 | カルシウム受容体調節剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005527625A JP2005527625A (ja) | 2005-09-15 |
| JP2005527625A5 true JP2005527625A5 (https=) | 2006-07-06 |
| JP4486882B2 JP4486882B2 (ja) | 2010-06-23 |
Family
ID=29587692
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004507434A Expired - Fee Related JP4486882B2 (ja) | 2002-05-23 | 2003-05-23 | カルシウム受容体調節アリールアルキルアミン |
| JP2010027494A Pending JP2010150268A (ja) | 2002-05-23 | 2010-02-10 | カルシウム受容体調節剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010027494A Pending JP2010150268A (ja) | 2002-05-23 | 2010-02-10 | カルシウム受容体調節剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6908935B2 (https=) |
| EP (1) | EP1509497A1 (https=) |
| JP (2) | JP4486882B2 (https=) |
| AU (1) | AU2003233671B2 (https=) |
| CA (1) | CA2486399C (https=) |
| MX (1) | MXPA04011471A (https=) |
| PL (1) | PL376438A1 (https=) |
| WO (1) | WO2003099776A1 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6908935B2 (en) * | 2002-05-23 | 2005-06-21 | Amgen Inc. | Calcium receptor modulating agents |
| JP4787150B2 (ja) * | 2003-03-06 | 2011-10-05 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Jnk阻害剤 |
| JP4185097B2 (ja) * | 2003-03-13 | 2008-11-19 | 出光興産株式会社 | 新規含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
| WO2005065050A2 (ja) * | 2003-12-25 | 2005-07-21 | Asahi Kasei Pharma Corporation | 2環化合物 |
| GB0400781D0 (en) * | 2004-01-14 | 2004-02-18 | Novartis Ag | Organic compounds |
| DE602005017471D1 (https=) * | 2004-03-02 | 2009-12-17 | Aventis Pharma Inc | |
| US8362274B2 (en) | 2004-05-28 | 2013-01-29 | Mitsubishi Tanabe Pharma Corporation | Arylalkylamine compound and process for preparing the same |
| US7361789B1 (en) | 2004-07-28 | 2008-04-22 | Amgen Inc. | Dihydronaphthalene compounds, compositions, uses thereof, and methods for synthesis |
| US20060276534A1 (en) * | 2005-03-17 | 2006-12-07 | Amgen Inc. | Methods of decreasing calcification |
| WO2006123725A1 (ja) * | 2005-05-19 | 2006-11-23 | Astellas Pharma Inc. | ピロリジン誘導体またはその塩 |
| WO2006130493A2 (en) * | 2005-05-31 | 2006-12-07 | Vertex Pharmaceuticals Incorporated | Heterocycles useful as modulators of ion channels |
| AU2006295340B2 (en) * | 2005-08-05 | 2010-11-11 | Amgen Inc. | Stable aqueous protein or antibody pharmaceutical formulations and their preparation |
| ES2400693T3 (es) * | 2005-09-02 | 2013-04-11 | Amgen Inc. | Regulación del equilibrio de fluido intestinal usando calcimiméticos |
| AU2006304778B2 (en) * | 2005-10-21 | 2011-04-28 | Amgen Inc. | Methods of decreasing vascular calcification using IL-1 inhibitors |
| WO2007087442A2 (en) * | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Substituted biaryl compounds for inflammation and immune-related uses |
| JP5309014B2 (ja) * | 2006-03-23 | 2013-10-09 | アムジエン・インコーポレーテツド | シナカルセットの多形体の製造および使用のための方法および組成物 |
| CN101437490A (zh) * | 2006-04-20 | 2009-05-20 | 安美基公司 | 稳定乳液配方 |
| GB0614579D0 (en) * | 2006-07-21 | 2006-08-30 | Black James Foundation | Pyrimidine derivatives |
| EP2049481A2 (en) * | 2006-08-09 | 2009-04-22 | SmithKline Beecham Corporation | Novel compounds as antagonists or inverse agonists for opioid receptors |
| TW200821276A (en) * | 2006-08-18 | 2008-05-16 | Leo Pharma As | Substituted acetylenic compounds useful for the treatment of diseases |
| JP5470653B2 (ja) * | 2006-10-26 | 2014-04-16 | アムジエン・インコーポレーテツド | カルシウム受容体調節剤 |
| MX2009004314A (es) * | 2006-11-13 | 2009-05-05 | Pfizer Prod Inc | Diaril, dipiridinil y arilpiridinilderivados y usos de los mismos. |
| TW200840566A (en) * | 2006-12-22 | 2008-10-16 | Esteve Labor Dr | Heterocyclyl-substituted-ethylamino-phenyl derivatives, their preparation and use as medicaments |
| CA2681582C (en) | 2007-03-30 | 2015-07-14 | Amgen Inc. | Methods of treating bowel disorders |
| EP2212284B1 (en) * | 2007-10-15 | 2014-04-30 | Amgen Inc. | Calcium receptor modulating agents |
| US8609655B2 (en) * | 2008-03-28 | 2013-12-17 | Amgen Inc. | Calcimimetic compound for use in the treatment of epithelial injury |
| WO2010042642A1 (en) * | 2008-10-08 | 2010-04-15 | Amgen Inc. | Calcium receptor modulating agents |
| WO2010052448A2 (en) * | 2008-11-05 | 2010-05-14 | Ucb Pharma S.A. | Fused pyrazine derivatives as kinase inhibitors |
| WO2010104882A1 (en) | 2009-03-10 | 2010-09-16 | Amgen Inc. | Methods of modulating sperm motility |
| DE102009015697A1 (de) | 2009-03-31 | 2010-10-07 | Markus Dr. Heinrich | Verfahren zur Arylierung von ringsubstituierten Phenolen und Phenylethern |
| WO2010136037A1 (en) | 2009-05-27 | 2010-12-02 | Leo Pharma A/S | Novel calcium sensing receptor modulating compounds and pharmaceutical use thereof |
| JP2012528084A (ja) | 2009-05-27 | 2012-11-12 | レオ ファーマ アクティーゼルスカブ | 新規のカルシウム感知受容体調節化合物およびその医薬用途 |
| WO2012000499A1 (en) | 2010-06-30 | 2012-01-05 | Leo Pharma A/S | New polymorphic form of a calcimimetic compound |
| EP2588445A1 (en) | 2010-06-30 | 2013-05-08 | Leo Pharma A/S | New polymorphic form of a calcimimetic compound |
| JP2014507375A (ja) | 2010-11-26 | 2014-03-27 | レオ ファーマ アクティーゼルスカブ | カルシウム感知受容体活性化合物 |
| WO2012069402A1 (en) | 2010-11-26 | 2012-05-31 | Leo Pharma A/S | Substituted cyclopentyl - azines as casr- active compounds |
| CN103270018A (zh) | 2010-11-26 | 2013-08-28 | 利奥制药有限公司 | 钙敏感受体激活化合物 |
| CN103228619A (zh) | 2010-11-26 | 2013-07-31 | 利奥制药有限公司 | 钙传感受体活性化合物 |
| AP2013007153A0 (en) * | 2011-03-18 | 2013-09-30 | Lupin Ltd | Benzo [B] [1,4] oxazin derivatives as calcium sensing receptor modulators |
| WO2014033604A1 (en) * | 2012-08-27 | 2014-03-06 | Lupin Limited | Arylalkylamine compounds as calcium sensing receptor modulators |
| GB201217330D0 (en) | 2012-09-28 | 2012-11-14 | Univ Cardiff | Therapeutic for treating inflammatory lung disorders |
| CN104292157A (zh) * | 2014-09-15 | 2015-01-21 | 湖南华腾制药有限公司 | 一种1-(喹啉-4-基)乙胺的制备方法 |
| WO2017037616A1 (en) * | 2015-08-31 | 2017-03-09 | Lupin Limited | Arylalkylamine compounds as calcium sensing receptor modulators |
| DE102015011861B4 (de) | 2015-09-10 | 2018-03-01 | Rudolf Schindler | Neue cyclische Carboxamide als NMDA NR2B Rezeptor Inhibitoren |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT72878B (en) | 1980-04-24 | 1983-03-29 | Merck & Co Inc | Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents |
| CN1192011C (zh) | 1991-08-23 | 2005-03-09 | Nps药物有限公司 | 对钙受体具活性的芳烷基胺化合物 |
| RU2147574C1 (ru) | 1991-08-23 | 2000-04-20 | Эн-Пи-Эс Фармасьютикалз, Инк. | Арилалкиламины, композиции, способы лечения и диагностики, способы идентификации соединения |
| US6011068A (en) | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6031003A (en) | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| EP0637237B1 (en) | 1993-02-23 | 2004-05-19 | Brigham And Women's Hospital, Inc. | Calcium receptor-active molecules |
| AU3414295A (en) | 1994-08-19 | 1996-03-14 | Nps Pharmaceuticals, Inc. | Methods and compounds active at metabotropic glutamate receptors useful for treatment of neurological disorders and diseases |
| AU3642795A (en) | 1994-09-27 | 1996-04-19 | Merck & Co., Inc. | Endothelin receptor antagonists for the treatment of emesis |
| US6211244B1 (en) | 1994-10-21 | 2001-04-03 | Nps Pharmaceuticals, Inc. | Calcium receptor-active compounds |
| US5585388A (en) | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
| DE69637587D1 (de) | 1995-07-26 | 2008-08-21 | Astrazeneca Ab | Chimäre rezeptoren und verfahren zur identifizieren verbindungen mit einem aktivität als metabotropischen glutamatrezeptoren sowie verwendung solcher verbindungen in der behandlung von neurologischer erkrankungen und neurologischenstörrungen |
| DE69733649T2 (de) | 1996-04-09 | 2006-05-18 | NPS Pharmaceuticals, Inc., Salt Lake City | Calcylitische verbindungen |
| EP0907631B1 (en) | 1996-05-01 | 2003-06-18 | Nps Pharmaceuticals, Inc. | Inorganic ion receptor-active compounds |
| US6362231B1 (en) | 1996-07-08 | 2002-03-26 | Nps Pharmaceuticals, Inc. | Calcium receptor active compounds |
| TR199902012T2 (xx) | 1997-02-21 | 2000-01-21 | Bayer Aktiengesellschaft | Arils�lfonamidler ve analoglar� |
| UY24949A1 (es) | 1997-04-08 | 2001-04-30 | Smithkline Beecham Corp | Compuestos calcilíticos |
| WO1999001439A1 (en) | 1997-07-03 | 1999-01-14 | Du Pont Pharmaceuticals Company | Aryl-and arylamino-substituted heterocycles as corticotropin releasing hormone antagonists |
| AU757488B2 (en) | 1998-03-25 | 2003-02-20 | Bristol-Myers Squibb Company | Imidazolone anorectic agents: III. heteroaryl derivatives |
| WO2000009491A1 (en) | 1998-08-12 | 2000-02-24 | Smithkline Beecham Corporation | Calcilytic compounds |
| AU760889B2 (en) | 1998-10-14 | 2003-05-22 | Ortho-Mcneil Pharmaceutical, Inc. | 1,2-disubstituted cyclopropanes |
| HRP20010603A2 (en) | 1999-02-24 | 2002-08-31 | Hoffmann La Roche | Phenyl-and pyridinyl derivatives |
| SI1157005T1 (en) | 1999-02-24 | 2005-02-28 | F. Hoffmann-La Roche Ag | 3-phenylpyridine derivatives and their use as nk-1 receptor antagonists |
| EP1074539B1 (en) | 1999-08-04 | 2007-10-17 | Sumitomo Chemical Company, Limited | Process for producing optically active 3,3,3,-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof |
| DE10028575A1 (de) | 2000-06-14 | 2002-03-14 | Basf Ag | Integrinliganden |
| FR2800735B1 (fr) | 1999-11-09 | 2002-02-01 | Centre Nat Rech Scient | Nouvelles aralkyle-1,2-diamines possedant une activite calcimimetique et leur mode de preparation |
| EP1116711B1 (de) | 1999-12-18 | 2005-12-14 | Wella Aktiengesellschaft | 2-Aminoalkyl-1,4-diaminobenzol-Derivate und diese Verbindungen enthaltende Färbemittel |
| FR2809396B1 (fr) | 2000-05-24 | 2005-10-14 | Centre Nat Rech Scient | Nouvelles molecules possedant une activite calcimimetique et leur mode de preparation |
| DE10028402A1 (de) | 2000-06-13 | 2001-12-20 | Merck Patent Gmbh | Pyridin-2-yl-aminoalkycarbonylglycyl-beta-alanin und Derivate |
| UY26780A1 (es) | 2000-06-15 | 2002-01-31 | Pharmacia Corp | Cicloalquil avb3 antagonistas |
| WO2003020723A1 (en) | 2001-08-30 | 2003-03-13 | Kyowa Hakko Kogyo Co., Ltd. | [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINE DERIVATIVE |
| US6908935B2 (en) * | 2002-05-23 | 2005-06-21 | Amgen Inc. | Calcium receptor modulating agents |
| US7176322B2 (en) | 2002-05-23 | 2007-02-13 | Amgen Inc. | Calcium receptor modulating agents |
-
2003
- 2003-05-22 US US10/444,946 patent/US6908935B2/en not_active Expired - Lifetime
- 2003-05-23 WO PCT/US2003/016401 patent/WO2003099776A1/en not_active Ceased
- 2003-05-23 MX MXPA04011471A patent/MXPA04011471A/es active IP Right Grant
- 2003-05-23 PL PL03376438A patent/PL376438A1/xx unknown
- 2003-05-23 AU AU2003233671A patent/AU2003233671B2/en not_active Ceased
- 2003-05-23 CA CA2486399A patent/CA2486399C/en not_active Expired - Fee Related
- 2003-05-23 JP JP2004507434A patent/JP4486882B2/ja not_active Expired - Fee Related
- 2003-05-23 EP EP03729111A patent/EP1509497A1/en not_active Withdrawn
-
2005
- 2005-02-18 US US11/061,084 patent/US7196102B2/en not_active Expired - Fee Related
-
2007
- 2007-01-30 US US11/700,336 patent/US7524873B2/en not_active Expired - Fee Related
-
2010
- 2010-02-10 JP JP2010027494A patent/JP2010150268A/ja active Pending
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