JP2009504791A5 - - Google Patents

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Publication number
JP2009504791A5
JP2009504791A5 JP2008527370A JP2008527370A JP2009504791A5 JP 2009504791 A5 JP2009504791 A5 JP 2009504791A5 JP 2008527370 A JP2008527370 A JP 2008527370A JP 2008527370 A JP2008527370 A JP 2008527370A JP 2009504791 A5 JP2009504791 A5 JP 2009504791A5
Authority
JP
Japan
Prior art keywords
formula
compound according
methyl
group
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008527370A
Other languages
English (en)
Japanese (ja)
Other versions
JP5237807B2 (ja
JP2009504791A (ja
Filing date
Publication date
Priority claimed from GB0517181A external-priority patent/GB0517181D0/en
Priority claimed from GB0517202A external-priority patent/GB0517202D0/en
Application filed filed Critical
Priority claimed from PCT/EP2006/008200 external-priority patent/WO2007022933A1/en
Publication of JP2009504791A publication Critical patent/JP2009504791A/ja
Publication of JP2009504791A5 publication Critical patent/JP2009504791A5/ja
Application granted granted Critical
Publication of JP5237807B2 publication Critical patent/JP5237807B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008527370A 2005-08-22 2006-08-18 ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体 Expired - Fee Related JP5237807B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0517181A GB0517181D0 (en) 2005-08-22 2005-08-22 Compounds
GB0517181.4 2005-08-22
GB0517202.8 2005-08-22
GB0517202A GB0517202D0 (en) 2005-08-22 2005-08-22 Compounds
PCT/EP2006/008200 WO2007022933A1 (en) 2005-08-22 2006-08-18 Triazole derivatives as modulators of dopamine d3 receptors

Publications (3)

Publication Number Publication Date
JP2009504791A JP2009504791A (ja) 2009-02-05
JP2009504791A5 true JP2009504791A5 (https=) 2009-10-01
JP5237807B2 JP5237807B2 (ja) 2013-07-17

Family

ID=37309176

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008527370A Expired - Fee Related JP5237807B2 (ja) 2005-08-22 2006-08-18 ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体

Country Status (6)

Country Link
US (1) US7799815B2 (https=)
EP (1) EP1919908B1 (https=)
JP (1) JP5237807B2 (https=)
AT (1) ATE487715T1 (https=)
DE (1) DE602006018152D1 (https=)
WO (1) WO2007022933A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1745040E (pt) * 2004-02-23 2010-03-08 Glaxo Group Ltd Derivados do azabiciclo3.1.0-hexano úteis como moduladores dos receptores d3 da dopamina
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
EP1891056B1 (en) * 2005-06-14 2010-10-13 Glaxo Group Limited Novel compounds
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
EP1915146A4 (en) 2005-07-27 2010-06-02 Dov Pharmaceutical Inc NOVEL 1-ARYL-3-AZABICYCLO [3.1.0] HEXANEES. PREPARATION AND USE FOR THE TREATMENT OF NEUROPSYCHIATRIC DISEASES
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517193D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Novel use
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517191D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
EP2007751B1 (en) * 2006-04-03 2013-08-21 Glaxo Group Limited Azabicyclo [3. 1. o] hexyl derivatives as modulators of dopamine d3 receptors
WO2007113258A1 (en) * 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. o] hexane derivatives as modulators of dopamine d3 receptors
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
EP2167083B1 (en) * 2007-06-06 2015-10-28 Euthymics Bioscience, Inc. 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
KR20120106697A (ko) 2009-06-26 2012-09-26 파나세아 바이오테크 리미티드 신규 아자비시클로헥산
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
US11447484B2 (en) 2018-01-26 2022-09-20 Shionogi & Co., Ltd. Cyclic compound having dopamine D3 receptor antagonistic effect
CN113956157B (zh) * 2021-11-18 2024-05-03 西安都创医药科技有限公司 一种合成2-甲酰基-1-环丙烷甲酸乙酯的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
TWI274750B (en) 1999-01-12 2007-03-01 Abbott Gmbh & Co Kg Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same
ES2264003T3 (es) * 2002-10-07 2006-12-16 Glaxo Group Limited Derivados de sulfonamida como agentges antipsicoticos.
DE10304870A1 (de) * 2003-02-06 2004-08-19 Abbott Gmbh & Co. Kg Triazolverbindungen und ihre therapeutische Verwendung
PT1745040E (pt) * 2004-02-23 2010-03-08 Glaxo Group Ltd Derivados do azabiciclo3.1.0-hexano úteis como moduladores dos receptores d3 da dopamina
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
EP1891056B1 (en) * 2005-06-14 2010-10-13 Glaxo Group Limited Novel compounds
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517191D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517193D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Novel use
EA200870404A1 (ru) * 2006-04-03 2009-04-28 Глэксо Груп Лимитед Производные азабицикло[3.1.0.]гексила в качестве модуляторов рецепторов допамина d3
GB0616574D0 (en) * 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds

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