|
DE60129222T2
(de)
|
2000-05-11 |
2008-03-06 |
Consejo Superior de Investigaciónes Científicas |
Heterocyclischen inhibitoren von glycogen synthase kinase gsk-3
|
|
EP1586318A1
(en)
*
|
2004-04-05 |
2005-10-19 |
Neuropharma S.A.U. |
Thiadiazolidinones as GSK-3 inhibitors
|
|
WO2006045581A1
(en)
*
|
2004-10-21 |
2006-05-04 |
Neuropharma, S.A. |
The use of 1, 2, 4-thiadiazolidine-3, 5-diones as ppar activators
|
|
ES2258406B1
(es)
*
|
2005-02-10 |
2007-12-01 |
Neuropharma, S.A. |
Uso de compuestos heterociclicos como agentes neurogenicos.
|
|
EP1749523A1
(en)
*
|
2005-07-29 |
2007-02-07 |
Neuropharma, S.A. |
GSK-3 inhibitors
|
|
US9180118B2
(en)
*
|
2006-07-18 |
2015-11-10 |
University Of Rochester |
Thiadiazolidinone derivatives
|
|
WO2008012031A2
(en)
*
|
2006-07-25 |
2008-01-31 |
Universität Bern |
Blockers of gsk3 for the prevention and treatment of pemphigus vulgaris
|
|
AU2007283113A1
(en)
|
2006-08-08 |
2008-02-14 |
Sanofi-Aventis |
Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use
|
|
EP2535336A1
(en)
|
2006-10-21 |
2012-12-19 |
Abbott GmbH & Co. KG |
Heterocyclic compounds and their use as glycogen synthase kinase 3 inhibitors
|
|
KR100829468B1
(ko)
*
|
2007-01-17 |
2008-05-16 |
한국화학연구원 |
신규한 1,2,4-티아다이아졸리딘-3,5-다이온 화합물 및 이의제조방법
|
|
KR100837785B1
(ko)
*
|
2007-01-17 |
2008-06-13 |
한국화학연구원 |
1,2,4-티아다이아졸리딘-3,5-다이온 화합물을 포함하는염증관련 질환의 치료 및 예방을 위한 약제학적 조성물
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
WO2009097995A1
(de)
*
|
2008-02-07 |
2009-08-13 |
Sanofi-Aventis |
Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
UY31968A
(es)
|
2008-07-09 |
2010-01-29 |
Sanofi Aventis |
Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
|
|
EP2177510A1
(en)
|
2008-10-17 |
2010-04-21 |
Universität des Saarlandes |
Allosteric protein kinase modulators
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
KR20120060207A
(ko)
|
2009-08-26 |
2012-06-11 |
사노피 |
신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2011151359A1
(en)
*
|
2010-06-02 |
2011-12-08 |
Noscira, S.A. |
Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative
|
|
EP2582709B1
(de)
|
2010-06-18 |
2018-01-24 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
MX336726B
(es)
|
2010-09-27 |
2016-01-27 |
Abbott Gmbh & Co Kg |
Compuestos heterociclicos y su uso como inhibidores de la glucogeno sintasa quinasa-3.
|
|
WO2012065065A1
(en)
*
|
2010-11-12 |
2012-05-18 |
Follica, Inc. |
Methods and compositions for modulating hair growth, wound healing and scar revision
|
|
AU2011338530B2
(en)
|
2010-12-06 |
2017-06-15 |
Follica, Inc. |
Methods for treating baldness and promoting hair growth
|
|
US9090592B2
(en)
|
2010-12-30 |
2015-07-28 |
AbbVie Deutschland GmbH & Co. KG |
Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
|
|
US8710050B2
(en)
|
2011-03-08 |
2014-04-29 |
Sanofi |
Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
EP2766349B1
(de)
|
2011-03-08 |
2016-06-01 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8828994B2
(en)
|
2011-03-08 |
2014-09-09 |
Sanofi |
Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
US8809325B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
|
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2012120058A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8871758B2
(en)
|
2011-03-08 |
2014-10-28 |
Sanofi |
Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
|
EP2683702B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2012149335A2
(en)
*
|
2011-04-28 |
2012-11-01 |
Richard Neubig |
Small molecule inhibitors of rgs proteins
|
|
EP2527323A1
(en)
|
2011-05-24 |
2012-11-28 |
Noscira, S.A. |
Urea carbonyl disulfide derivatives and their therapeutic uses
|
|
WO2012170657A1
(en)
*
|
2011-06-07 |
2012-12-13 |
Georgetown University |
Targeting gsk-3beta for the treatment of parkinson's disease
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
US9371299B2
(en)
*
|
2012-02-24 |
2016-06-21 |
Asd Therapeutics Partners, Llc |
Thiadiazolidinediones as GSK-3 inhibitors
|
|
RU2509155C1
(ru)
*
|
2012-10-25 |
2014-03-10 |
Федеральное государственное бюджетное учреждение науки Институт биохимии им. А.Н. Баха Российской академии наук |
Способ детекции белков в амилоидном состоянии и набор для детекции белков в амилоидном состоянии
|
|
CN103992312A
(zh)
*
|
2013-02-18 |
2014-08-20 |
江苏欧威医药有限公司 |
1,2,4-噻二唑-3,5-二酮衍生物及其药物组合物和应用
|
|
CN103992313A
(zh)
*
|
2013-02-18 |
2014-08-20 |
江苏欧威医药有限公司 |
1,2,4-噻二唑-3,5-二酮衍生物及其药物组合物和用途
|
|
WO2015075051A1
(en)
|
2013-11-19 |
2015-05-28 |
Universitaet Des Saarlandes |
Allosteric inhibitors of atypical protein kinases c
|
|
US20170165230A1
(en)
|
2014-04-09 |
2017-06-15 |
Christopher Rudd |
Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
|
|
JP6663863B2
(ja)
|
2014-06-12 |
2020-03-13 |
シーダーズ−サイナイ メディカル センター |
がん治療のための組成物及び方法
|
|
CN107151235B
(zh)
*
|
2016-03-04 |
2019-12-13 |
上海市计划生育科学研究所 |
噻二唑烷二酮基gsk3抑制剂在调节精子运动能力中的用途
|
|
WO2017153834A1
(en)
*
|
2016-03-10 |
2017-09-14 |
Alma Mater Studiorum - Universitá Di Bologna |
TREATMENT OF CDKL5 DISORDERS WITH GSK3β INHIBITOR TIDEGLUSIB
|
|
GB201617820D0
(en)
*
|
2016-10-21 |
2016-12-07 |
King S College London |
Dental treatment
|
|
WO2018226721A1
(en)
*
|
2017-06-06 |
2018-12-13 |
The J. David Gladstone Institutes |
Compositions and methods for reactivating latent immunodeficiency virus using a gsk-3 inhibitor
|
|
WO2020033919A1
(en)
|
2018-08-10 |
2020-02-13 |
Diapin Therapeutics, Llc |
Tri-peptides and treatment of metabolic, cardiovascular and inflammatory disorders
|
|
US20230218644A1
(en)
|
2020-04-16 |
2023-07-13 |
Som Innovation Biotech, S.A. |
Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
|
|
CN113827592B
(zh)
*
|
2020-06-24 |
2024-06-18 |
中国科学院上海药物研究所 |
一种噻二唑烷二酮基化合物在治疗致病性感染中的应用
|
|
AU2022219157A1
(en)
*
|
2021-02-11 |
2023-08-10 |
Venca Research, Inc. |
Compositions and methods for treating arrhythmogenic cardiomyopathy
|
|
WO2022182699A1
(en)
|
2021-02-24 |
2022-09-01 |
Teva Pharmaceuticals International Gmbh |
Solid state forms of tideglusib and process for preparation thereof
|
|
EP4340832A1
(en)
|
2021-05-21 |
2024-03-27 |
Amo Pharma Ltd. |
Method of treating rna repeat mediated diseases with rna repeat binding compound
|
|
EP4094760A1
(en)
|
2021-05-24 |
2022-11-30 |
Consejo Superior De Investigaciones Científicas |
Thiadiazolidinones for their use in the treatment of limb-girdle muscular dystrophy
|
|
CN115197167B
(zh)
*
|
2022-07-22 |
2023-07-28 |
中国药科大学 |
1,2,4-噻二唑烷-3,5-二酮化合物及其制备方法和应用
|
|
CN117986202B
(zh)
*
|
2024-04-03 |
2024-06-14 |
中国药科大学 |
具有ptpn2抑制活性的1,2,4-噻二唑烷-3,5-二酮化合物及其制备方法和应用
|