|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
|
US4328245A
(en)
|
1981-02-13 |
1982-05-04 |
Syntex (U.S.A.) Inc. |
Carbonate diester solutions of PGE-type compounds
|
|
US4410545A
(en)
|
1981-02-13 |
1983-10-18 |
Syntex (U.S.A.) Inc. |
Carbonate diester solutions of PGE-type compounds
|
|
US4409239A
(en)
|
1982-01-21 |
1983-10-11 |
Syntex (U.S.A.) Inc. |
Propylene glycol diester solutions of PGE-type compounds
|
|
ES8702440A1
(es)
|
1984-10-04 |
1986-12-16 |
Monsanto Co |
Un procedimiento para la preparacion de una composicion de polipeptido inyectable sustancialmente no acuosa.
|
|
IE58110B1
(en)
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
|
US5052558A
(en)
|
1987-12-23 |
1991-10-01 |
Entravision, Inc. |
Packaged pharmaceutical product
|
|
US5033252A
(en)
|
1987-12-23 |
1991-07-23 |
Entravision, Inc. |
Method of packaging and sterilizing a pharmaceutical product
|
|
US5073543A
(en)
|
1988-07-21 |
1991-12-17 |
G. D. Searle & Co. |
Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
|
|
US5612059A
(en)
|
1988-08-30 |
1997-03-18 |
Pfizer Inc. |
Use of asymmetric membranes in delivery devices
|
|
IT1229203B
(it)
|
1989-03-22 |
1991-07-25 |
Bioresearch Spa |
Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
|
|
PH30995A
(en)
|
1989-07-07 |
1997-12-23 |
Novartis Inc |
Sustained release formulations of water soluble peptides.
|
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
|
IT1246382B
(it)
|
1990-04-17 |
1994-11-18 |
Eurand Int |
Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
|
|
US5733566A
(en)
|
1990-05-15 |
1998-03-31 |
Alkermes Controlled Therapeutics Inc. Ii |
Controlled release of antiparasitic agents in animals
|
|
US5543390A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University |
Covalent microparticle-drug conjugates for biological targeting
|
|
US5580578A
(en)
|
1992-01-27 |
1996-12-03 |
Euro-Celtique, S.A. |
Controlled release formulations coated with aqueous dispersions of acrylic polymers
|
|
US5323907A
(en)
|
1992-06-23 |
1994-06-28 |
Multi-Comp, Inc. |
Child resistant package assembly for dispensing pharmaceutical medications
|
|
TW333456B
(en)
|
1992-12-07 |
1998-06-11 |
Takeda Pharm Ind Co Ltd |
A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
|
|
US5591767A
(en)
|
1993-01-25 |
1997-01-07 |
Pharmetrix Corporation |
Liquid reservoir transdermal patch for the administration of ketorolac
|
|
US6274552B1
(en)
|
1993-03-18 |
2001-08-14 |
Cytimmune Sciences, Inc. |
Composition and method for delivery of biologically-active factors
|
|
US5523092A
(en)
|
1993-04-14 |
1996-06-04 |
Emory University |
Device for local drug delivery and methods for using the same
|
|
US5985307A
(en)
|
1993-04-14 |
1999-11-16 |
Emory University |
Device and method for non-occlusive localized drug delivery
|
|
US6087324A
(en)
|
1993-06-24 |
2000-07-11 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
|
US6004534A
(en)
|
1993-07-23 |
1999-12-21 |
Massachusetts Institute Of Technology |
Targeted polymerized liposomes for improved drug delivery
|
|
US5958458A
(en)
|
1994-06-15 |
1999-09-28 |
Dumex-Alpharma A/S |
Pharmaceutical multiple unit particulate formulation in the form of coated cores
|
|
IT1270594B
(it)
|
1994-07-07 |
1997-05-07 |
Recordati Chem Pharm |
Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
|
|
US5759542A
(en)
|
1994-08-05 |
1998-06-02 |
New England Deaconess Hospital Corporation |
Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases
|
|
US5660854A
(en)
|
1994-11-28 |
1997-08-26 |
Haynes; Duncan H |
Drug releasing surgical implant or dressing material
|
|
US6316652B1
(en)
|
1995-06-06 |
2001-11-13 |
Kosta Steliou |
Drug mitochondrial targeting agents
|
|
US5798119A
(en)
|
1995-06-13 |
1998-08-25 |
S. C. Johnson & Son, Inc. |
Osmotic-delivery devices having vapor-permeable coatings
|
|
EP0835101B1
(en)
|
1995-06-27 |
2004-06-09 |
Takeda Chemical Industries, Ltd. |
Method of producing sustained-release preparation
|
|
TW448055B
(en)
|
1995-09-04 |
2001-08-01 |
Takeda Chemical Industries Ltd |
Method of production of sustained-release preparation
|
|
JP2909418B2
(ja)
|
1995-09-18 |
1999-06-23 |
株式会社資生堂 |
薬物の遅延放出型マイクロスフイア
|
|
US6039975A
(en)
|
1995-10-17 |
2000-03-21 |
Hoffman-La Roche Inc. |
Colon targeted delivery system
|
|
US5980945A
(en)
|
1996-01-16 |
1999-11-09 |
Societe De Conseils De Recherches Et D'applications Scientifique S.A. |
Sustained release drug formulations
|
|
TW345603B
(en)
|
1996-05-29 |
1998-11-21 |
Gmundner Fertigteile Gmbh |
A noise control device for tracks
|
|
US6264970B1
(en)
|
1996-06-26 |
2001-07-24 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
|
US6419961B1
(en)
|
1996-08-29 |
2002-07-16 |
Takeda Chemical Industries, Ltd. |
Sustained release microcapsules of a bioactive substance and a biodegradable polymer
|
|
US6375987B1
(en)
|
1996-10-01 |
2002-04-23 |
Gattefossé, S.A. |
Process for the manufacture of pharmaceutical composition with modified release of active principle comprising the matrix
|
|
KR100353304B1
(ko)
|
1996-10-01 |
2002-09-30 |
에스알아이 인터내셔널 |
맛이 차폐된 마이크로캡슐 조성물 및 이것의 제조 방법
|
|
CA2217134A1
(en)
|
1996-10-09 |
1998-04-09 |
Sumitomo Pharmaceuticals Co., Ltd. |
Sustained release formulation
|
|
DK0839525T3
(da)
|
1996-10-31 |
2004-11-29 |
Takeda Pharmaceutical |
Præparat med forlænget frigivelse
|
|
US6131570A
(en)
|
1998-06-30 |
2000-10-17 |
Aradigm Corporation |
Temperature controlling device for aerosol drug delivery
|
|
DE19648576C2
(de)
|
1996-11-23 |
1999-08-12 |
Lohmann Therapie Syst Lts |
Lutschtablette zur modifizierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt
|
|
ZA9711385B
(en)
|
1996-12-20 |
1999-06-18 |
Takeda Chemical Industries Ltd |
Method of producing a sustained-release preparation
|
|
US5891474A
(en)
|
1997-01-29 |
1999-04-06 |
Poli Industria Chimica, S.P.A. |
Time-specific controlled release dosage formulations and method of preparing same
|
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
US5990146A
(en)
*
|
1997-08-20 |
1999-11-23 |
Warner-Lambert Company |
Benzimidazoles for inhibiting protein tyrosine kinase mediated cellular proliferation
|
|
US6350458B1
(en)
|
1998-02-10 |
2002-02-26 |
Generex Pharmaceuticals Incorporated |
Mixed micellar drug deliver system and method of preparation
|
|
US6613358B2
(en)
|
1998-03-18 |
2003-09-02 |
Theodore W. Randolph |
Sustained-release composition including amorphous polymer
|
|
US6048736A
(en)
|
1998-04-29 |
2000-04-11 |
Kosak; Kenneth M. |
Cyclodextrin polymers for carrying and releasing drugs
|
|
KR19990085365A
(ko)
|
1998-05-16 |
1999-12-06 |
허영섭 |
지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법
|
|
US7169410B1
(en)
|
1998-05-19 |
2007-01-30 |
Sdg, Inc. |
Targeted liposomal drug delivery system
|
|
CA2653839A1
(en)
|
1998-11-02 |
2000-05-11 |
John G. Devane |
Multiparticulate modified release composition
|
|
US6248363B1
(en)
|
1999-11-23 |
2001-06-19 |
Lipocine, Inc. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
|
US6623756B1
(en)
|
2000-04-27 |
2003-09-23 |
Noveon Ip Holdings Corp. |
Directly compressed solid dosage articles
|
|
BR0113626A
(pt)
|
2000-08-30 |
2003-06-17 |
Pfizer Prod Inc |
Formulações de liberação sustentada para secretores de hormÈnio do crescimento
|
|
ATE482692T1
(de)
|
2001-07-27 |
2010-10-15 |
Astellas Pharma Inc |
Zusammensetzung enthaltend feine körner mit verzögerter freisetzung für in der mundhöhle schnell zerfallende tabletten
|
|
HUP0401686A3
(en)
|
2001-09-28 |
2008-04-28 |
Mcneil Ppc Inc |
Dosage forms having an inner core and outer shell with different shapes
|
|
WO2003030902A1
(en)
|
2001-10-09 |
2003-04-17 |
Tularik Inc. |
Imidazole derivates as anti-inflammatory agents
|
|
PL362378A1
(en)
|
2001-12-19 |
2004-10-18 |
Astrazeneca Ab |
New film coating
|
|
US6958161B2
(en)
|
2002-04-12 |
2005-10-25 |
F H Faulding & Co Limited |
Modified release coated drug preparation
|
|
US7485322B2
(en)
|
2002-12-24 |
2009-02-03 |
Lek Pharmaceuticals D.D. |
Modified release pharmaceutical composition
|
|
US20060106020A1
(en)
*
|
2004-04-28 |
2006-05-18 |
Rodgers James D |
Tetracyclic inhibitors of Janus kinases
|
|
US7427414B2
(en)
|
2006-01-18 |
2008-09-23 |
Astron Research Limited |
Modified release oral dosage form using co-polymer of polyvinyl acetate
|
|
WO2007142755A2
(en)
*
|
2006-05-31 |
2007-12-13 |
The Regents Of The University Of California |
Purine analogs
|
|
AU2010311378B2
(en)
|
2009-10-29 |
2014-04-24 |
Vectura Limited |
N-containing heteroaryl derivatives as JAK3 kinase inhibitors
|
|
CN102712640A
(zh)
*
|
2010-01-12 |
2012-10-03 |
弗·哈夫曼-拉罗切有限公司 |
三环杂环化合物、其组合物和应用方法
|
|
WO2011099832A2
(en)
|
2010-02-12 |
2011-08-18 |
Crystalgenomics, Inc. |
Novel benzimidazole compound, preparation method thereof and pharmaceutical composition comprising the same
|
|
MX2013001313A
(es)
|
2010-08-05 |
2013-06-13 |
Amgen Inc |
Compuestos de bencimidazol y azabencimidazol que inhiben la cinasa del linfoma anaplasico.
|
|
HK1202377A1
(en)
|
2011-11-14 |
2015-10-02 |
Tesaro Inc. |
Modulating certain tyrosine kinases
|
|
CA2854188A1
(en)
|
2011-11-14 |
2013-05-23 |
Synta Pharmaceuticals Corp. |
Combination therapy of hsp90 inhibitors with braf inhibitors
|
|
WO2013153539A1
(en)
*
|
2012-04-13 |
2013-10-17 |
Glenmark Pharmaceuticals S.A. |
Tricyclic compounds as tec kinase inhibitors
|
|
CA2871540A1
(en)
|
2012-05-10 |
2013-11-14 |
Synta Pharmaceuticals Corp. |
Treating cancer with hsp90 inhibitory compounds
|
|
CN104520291A
(zh)
*
|
2012-06-06 |
2015-04-15 |
Irm责任有限公司 |
用于调节egfr活性的化合物和组合物
|
|
JO3300B1
(ar)
|
2012-06-06 |
2018-09-16 |
Novartis Ag |
مركبات وتركيبات لتعديل نشاط egfr
|
|
TR201807207T4
(tr)
|
2012-06-11 |
2018-06-21 |
Ucb Biopharma Sprl |
Tnf-alfa modüle edici benzimidazol bileşikleri.
|
|
EA029718B1
(ru)
|
2012-06-27 |
2018-05-31 |
4-Эс-Си Дискавери Гмбх |
Бифтордиоксалан-аминобензимидазольные ингибиторы киназы для лечения рака, аутоиммунного воспаления и нарушений цнс
|
|
US9573958B2
(en)
*
|
2012-08-31 |
2017-02-21 |
Principia Biopharma, Inc. |
Benzimidazole derivatives as ITK inhibitors
|
|
WO2015134210A1
(en)
|
2014-03-03 |
2015-09-11 |
Principia Biopharma, Inc. |
BENZIMIDAZOLE DERIVATIVES AS RLK and ITK INHIBITORS
|
|
CN114940673B
(zh)
|
2014-03-20 |
2025-03-18 |
卡佩拉医疗公司 |
苯并咪唑衍生物作为erbb酪氨酸激酶抑制剂用于治疗癌症
|
|
US10202398B2
(en)
|
2014-03-20 |
2019-02-12 |
Capella Therapeutics, Inc. |
Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer
|
|
CN104447765A
(zh)
|
2014-12-31 |
2015-03-25 |
深圳铂立健医药有限公司 |
三环化合物及其药物组合物和应用
|