JP2016503052A5 - - Google Patents
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- Publication number
- JP2016503052A5 JP2016503052A5 JP2015548889A JP2015548889A JP2016503052A5 JP 2016503052 A5 JP2016503052 A5 JP 2016503052A5 JP 2015548889 A JP2015548889 A JP 2015548889A JP 2015548889 A JP2015548889 A JP 2015548889A JP 2016503052 A5 JP2016503052 A5 JP 2016503052A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- cor
- cycloalkyl
- heterocyclyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3600/MUM/2012 | 2012-12-24 | ||
| IN3600MU2012 | 2012-12-24 | ||
| PCT/IN2013/000796 WO2014102818A1 (en) | 2012-12-24 | 2013-12-23 | Novel quinolone derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503052A JP2016503052A (ja) | 2016-02-01 |
| JP2016503052A5 true JP2016503052A5 (enExample) | 2016-06-23 |
| JP6026013B2 JP6026013B2 (ja) | 2016-11-16 |
Family
ID=54148255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015548889A Active JP6026013B2 (ja) | 2012-12-24 | 2013-12-23 | 新規キノロン誘導体 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US9394300B2 (enExample) |
| EP (1) | EP2935221B1 (enExample) |
| JP (1) | JP6026013B2 (enExample) |
| KR (1) | KR101733901B1 (enExample) |
| CN (1) | CN104903295B (enExample) |
| AP (1) | AP2015008502A0 (enExample) |
| AR (1) | AR094300A1 (enExample) |
| AU (1) | AU2013368843B2 (enExample) |
| BR (1) | BR112015014222B1 (enExample) |
| CA (1) | CA2894636C (enExample) |
| CL (1) | CL2015001802A1 (enExample) |
| EA (1) | EA028402B1 (enExample) |
| ES (1) | ES2660288T3 (enExample) |
| IL (1) | IL239109B (enExample) |
| JO (1) | JO3781B1 (enExample) |
| MA (1) | MA38138A1 (enExample) |
| MX (1) | MX373392B (enExample) |
| MY (1) | MY175854A (enExample) |
| NZ (1) | NZ708605A (enExample) |
| PH (1) | PH12015501452B1 (enExample) |
| SG (1) | SG11201504458XA (enExample) |
| TR (1) | TR201802305T4 (enExample) |
| TW (1) | TWI598339B (enExample) |
| UA (1) | UA117122C2 (enExample) |
| WO (1) | WO2014102818A1 (enExample) |
| ZA (1) | ZA201503814B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105384687B (zh) * | 2014-09-02 | 2018-05-01 | 广东东阳光药业有限公司 | 喹啉酮类化合物及其在药物中应用 |
| WO2016045125A1 (en) | 2014-09-28 | 2016-03-31 | Merck Sharp & Dohme Corp. | Inhibitors of hif prolyl hydroxylase |
| CL2015003047A1 (es) * | 2015-10-15 | 2016-06-17 | Univ Chile | Método ex vivo para detectar precozmente injuria renal aguda en pacientes críticos, que comprende la mediciom en una muestra de tres proteinas como biomarcadores, factor de crecimiento fibroblástico 23, klotho y eritropoyetina |
| JOP20190024A1 (ar) | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| CN108069957B (zh) * | 2016-11-09 | 2022-11-04 | 广东东阳光药业有限公司 | 脯氨酰羟化酶抑制剂及其用途 |
| AU2018264313B2 (en) | 2017-05-09 | 2020-06-04 | Kind Pharmaceutical | Indolizine derivatives and application thereof in medicine |
| US10836769B2 (en) | 2018-02-26 | 2020-11-17 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| TW202200547A (zh) * | 2020-03-13 | 2022-01-01 | 印度商卡地拉保健有限公司 | 喹啉酮化合物的新穎鹽類 |
| TW202207930A (zh) * | 2020-03-17 | 2022-03-01 | 印度商卡地拉保健有限公司 | 包含ｈｉｆ脯胺醯基羥化酶抑制劑之調和物 |
| WO2021216530A1 (en) | 2020-04-20 | 2021-10-28 | Akebia Therapeutics, Inc. | Treatment of viral infections, of organ injury, and of related conditions using a hif prolyl hydroxylase inhibitor or a hif-alpha stabilizer |
| CN115666539A (zh) * | 2020-05-29 | 2023-01-31 | 兹杜斯生命科学有限公司 | 银屑病和皮肤炎性疾病的治疗 |
| EP4157220A1 (en) * | 2020-06-01 | 2023-04-05 | Zydus Lifesciences Limited | Treatment for the inflammatory bowel disease |
| WO2022150623A1 (en) | 2021-01-08 | 2022-07-14 | Akebia Therapeutics, Inc. | Compounds and composition for the treatment of anemia |
| US20240300899A1 (en) * | 2021-03-19 | 2024-09-12 | Zydus Lifesciences Limited | A quinolone compound in solid forms and processes for the preparation thereof |
| WO2022195532A1 (en) * | 2021-03-19 | 2022-09-22 | Zydus Lifesciences Ltd. | Treatment for sickle cell anaemia |
| WO2022238745A1 (en) * | 2021-05-14 | 2022-11-17 | Zydus Lifesciences Limited | Topical pharmaceutical composition of hif prolyl hydroxylase inhibitors |
| EP4347022A1 (en) | 2021-05-27 | 2024-04-10 | Keryx Biopharmaceuticals, Inc. | Pediatric formulations of ferric citrate |
| CN113549011B (zh) * | 2021-08-10 | 2023-05-09 | 广东东阳光药业有限公司 | 德度司他的共晶或盐及其制备方法和用途 |
| KR20240063900A (ko) * | 2021-09-20 | 2024-05-10 | 자이두스 라이프사이언시즈 리미티드 | 데시더스타트 입자 및 이의 조성물 |
| US20250387385A1 (en) * | 2022-06-24 | 2025-12-25 | Zydus Lifesciences Limited | Treatment for glomerular diseases |
| EP4565233A1 (en) * | 2022-08-01 | 2025-06-11 | Zydus Lifesciences Limited | Treatment for aplastic anemia (aa) |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ270267A (en) | 1993-12-30 | 1997-03-24 | Hoechst Ag | 3-hydroxypyridin-2yl (and -quinolin-2-yl) carboxamide derivatives and pharmaceutical compositions |
| CN102718708A (zh) | 2003-06-06 | 2012-10-10 | 菲布罗根有限公司 | 含氮杂芳基化合物及其在增加内源性促红细胞生成素中的用途 |
| JP4792048B2 (ja) * | 2005-03-02 | 2011-10-12 | ファイブロゲン インコーポレイティッド | チエノピリジン化合物およびその使用方法 |
| WO2007038571A2 (en) * | 2005-09-26 | 2007-04-05 | Smithkline Beecham Corporation | Prolyl hydroxylase antagonists |
| CA2634168C (en) | 2005-12-09 | 2013-04-23 | Amgen Inc. | Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof |
| TW200808793A (en) * | 2006-03-07 | 2008-02-16 | Smithkline Beecham Corp | Prolyl hydroxylase inhibitors |
| EP3124489B1 (en) * | 2006-04-04 | 2020-07-15 | Fibrogen, Inc. | Thiazolo-pyridine compounds as hif modulators |
| WO2007136990A2 (en) * | 2006-05-16 | 2007-11-29 | Smithkline Beecham Corporation | Prolyl hydroxylase inhibitors |
| JP2009543867A (ja) * | 2006-07-17 | 2009-12-10 | メルク エンド カムパニー インコーポレーテッド | 抗ｈｉｖ剤としての１−ヒドロキシナフチリジン化合物 |
| WO2008076425A1 (en) * | 2006-12-18 | 2008-06-26 | Amgen Inc. | Azaquinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof |
| JP2010524935A (ja) * | 2007-04-18 | 2010-07-22 | メルク・シャープ・エンド・ドーム・コーポレイション | 新規１，８−ナフチリジン化合物 |
| ES2442847T3 (es) * | 2007-04-18 | 2014-02-13 | Amgen, Inc | Quinolonas y azaquinolonas que inhiben la prolil hidroxilasa |
| WO2008137084A2 (en) * | 2007-05-04 | 2008-11-13 | Amgen Inc. | Diazaquinolones that inhibit prolyl hydroxylase activity |
| ES2389063T3 (es) * | 2007-05-04 | 2012-10-22 | Amgen, Inc | Derivados de tienopiridina y tiazolopiridina que inhiben la actividad prolil hidroxilasa |
| WO2008138060A1 (en) * | 2007-05-16 | 2008-11-20 | Cowper Norman T | System and method for maximising solids concentration of slurry pumped through a pipeline |
| EP2224926A4 (en) * | 2007-11-30 | 2010-12-01 | Glaxosmithkline Llc | INHIBITORS OF PROLYL HYDROXYLASES |
| CA2716798A1 (en) * | 2008-02-25 | 2009-09-03 | Merck Sharp & Dohme Corp. | Tetrahydrofuropyridones |
| AU2009217541A1 (en) * | 2008-02-25 | 2009-09-03 | Merck Sharp & Dohme Corp. | Tetrahydrothieno pyridines |
| AU2009217543A1 (en) * | 2008-02-25 | 2009-09-03 | Merck Sharp & Dohme Corp. | Tetrahydro-1H-pyrrolo fused pyridones |
| US20110098324A1 (en) * | 2008-06-25 | 2011-04-28 | Brackley Iii James A | Prolyl hydroxylase inhibitors |
| HRP20140705T1 (hr) | 2009-07-17 | 2014-09-12 | Japan Tobacco, Inc. | Spoj triazolopiridina i njegovo djelovanje kao inhibitora prolil hidroksilaze i induktora proizvodnje eritropoetina |
| BR112012003701A2 (pt) * | 2009-08-20 | 2019-09-24 | Vifor Int Ag | "novos antagonistas de quinolina-hepcidina" |
| US8921389B2 (en) | 2011-02-02 | 2014-12-30 | Fibrogen, Inc. | Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase |
| WO2013043621A1 (en) | 2011-09-23 | 2013-03-28 | Merck Sharp & Dohme Corp. | Substituted pyrimidines |
| CA2863279A1 (en) * | 2012-01-31 | 2013-08-08 | Toyama Chemical Co., Ltd. | Heterocyclic compound having anti-hiv activity |
-
2013
- 2013-12-23 WO PCT/IN2013/000796 patent/WO2014102818A1/en not_active Ceased
- 2013-12-23 ES ES13828997.0T patent/ES2660288T3/es active Active
- 2013-12-23 JO JOP/2013/0383A patent/JO3781B1/ar active
- 2013-12-23 BR BR112015014222-2A patent/BR112015014222B1/pt active IP Right Grant
- 2013-12-23 SG SG11201504458XA patent/SG11201504458XA/en unknown
- 2013-12-23 AP AP2015008502A patent/AP2015008502A0/xx unknown
- 2013-12-23 CN CN201380067856.4A patent/CN104903295B/zh active Active
- 2013-12-23 KR KR1020157016080A patent/KR101733901B1/ko active Active
- 2013-12-23 JP JP2015548889A patent/JP6026013B2/ja active Active
- 2013-12-23 AU AU2013368843A patent/AU2013368843B2/en active Active
- 2013-12-23 US US14/652,024 patent/US9394300B2/en active Active
- 2013-12-23 NZ NZ708605A patent/NZ708605A/en unknown
- 2013-12-23 EP EP13828997.0A patent/EP2935221B1/en active Active
- 2013-12-23 MY MYPI2015001457A patent/MY175854A/en unknown
- 2013-12-23 TR TR2018/02305T patent/TR201802305T4/tr unknown
- 2013-12-23 CA CA2894636A patent/CA2894636C/en active Active
- 2013-12-23 EA EA201591195A patent/EA028402B1/ru not_active IP Right Cessation
- 2013-12-23 MX MX2015008233A patent/MX373392B/es active IP Right Grant
- 2013-12-23 TW TW102147766A patent/TWI598339B/zh active
- 2013-12-23 UA UAA201506784A patent/UA117122C2/uk unknown
- 2013-12-27 AR ARP130105055A patent/AR094300A1/es active IP Right Grant
-
2015
- 2015-05-27 ZA ZA2015/03814A patent/ZA201503814B/en unknown
- 2015-05-29 MA MA38138A patent/MA38138A1/fr unknown
- 2015-06-01 IL IL239109A patent/IL239109B/en active IP Right Grant
- 2015-06-22 CL CL2015001802A patent/CL2015001802A1/es unknown
- 2015-06-23 PH PH12015501452A patent/PH12015501452B1/en unknown
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