|
KR100509388B1
(ko)
|
1996-10-18 |
2005-08-23 |
버텍스 파마슈티칼스 인코포레이티드 |
세린 프로테아제, 특히 간염 ｃ 바이러스 ｎｓ３ 프로테아제의 저해제
|
|
US7491794B2
(en)
*
|
2003-10-14 |
2009-02-17 |
Intermune, Inc. |
Macrocyclic compounds as inhibitors of viral replication
|
|
US8696298B2
(en)
*
|
2003-11-10 |
2014-04-15 |
Brooks Automation, Inc. |
Semiconductor manufacturing process modules
|
|
US10086511B2
(en)
|
2003-11-10 |
2018-10-02 |
Brooks Automation, Inc. |
Semiconductor manufacturing systems
|
|
CN1946691A
(zh)
*
|
2004-02-27 |
2007-04-11 |
先灵公司 |
作为丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的化合物
|
|
US7635694B2
(en)
*
|
2004-02-27 |
2009-12-22 |
Schering Corporation |
Cyclobutenedione-containing compounds as inhibitors of hepatitis C virus NS3 serine protease
|
|
US20070237818A1
(en)
*
|
2005-06-02 |
2007-10-11 |
Malcolm Bruce A |
Controlled-release formulation of HCV protease inhibitor and methods using the same
|
|
US20060276404A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Anima Ghosal |
Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
|
|
US20060275366A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Controlled-release formulation
|
|
AU2006252623A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Controlled-release formulation useful for treating disorders associated with hepatitis C virus
|
|
WO2006130552A2
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis c virus
|
|
US20060276407A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
|
US20070021351A1
(en)
*
|
2005-06-02 |
2007-01-25 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor
|
|
AU2006252519B2
(en)
|
2005-06-02 |
2012-08-30 |
Merck Sharp & Dohme Corp. |
HCV protease inhibitors in combination with food
|
|
US20060281689A1
(en)
*
|
2005-06-02 |
2006-12-14 |
Schering Corporation |
Method for modulating activity of HCV protease through use of a novel HCV protease inhibitor to reduce duration of treatment period
|
|
NZ563365A
(en)
*
|
2005-06-02 |
2011-02-25 |
Schering Corp |
Combination of HCV protease inhibitors with a surfactant
|
|
MX2008001166A
(es)
|
2005-07-25 |
2008-03-18 |
Intermune Inc |
Nuevos inhibidores macrociclicos de la replicacion del virus de hepatitis c.
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
AU2006301966A1
(en)
|
2005-10-11 |
2007-04-19 |
Array Biopharma, Inc. |
Compounds and methods for inhibiting hepatitis C viral replication
|
|
EP2392589A3
(en)
|
2005-11-11 |
2012-06-20 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
|
US7705138B2
(en)
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
|
US7816348B2
(en)
|
2006-02-03 |
2010-10-19 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
EP2007789B1
(en)
|
2006-04-11 |
2015-05-20 |
Novartis AG |
Spirocyclic HCV/HIV inhibitors and their uses
|
|
US20080045530A1
(en)
*
|
2006-04-11 |
2008-02-21 |
Trixi Brandl |
Organic Compounds and Their Uses
|
|
AR060385A1
(es)
*
|
2006-04-11 |
2008-06-11 |
Novartis Ag |
Compuestos organicos y sus usos
|
|
KR20090024834A
(ko)
|
2006-07-05 |
2009-03-09 |
인터뮨, 인크. |
Ｃ형 간염 바이러스 복제의 신규 억제제
|
|
JP2010500978A
(ja)
|
2006-08-17 |
2010-01-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ウイルスポリメラーゼインヒビター
|
|
CA2673111A1
(en)
|
2006-12-07 |
2008-06-19 |
Schering Corporation |
Ph sensitive matrix formulation
|
|
US20080219810A1
(en)
*
|
2007-03-05 |
2008-09-11 |
Van Der Meulen Peter |
Semiconductor manufacturing process modules
|
|
MX2009010207A
(es)
*
|
2007-03-23 |
2009-10-19 |
Schering Corp |
Peptidos de hidrazido como inhibidores de proteasa ns3 de virus de hepatitis c.
|
|
JP2010522172A
(ja)
*
|
2007-03-23 |
2010-07-01 |
シェーリング コーポレイション |
Ｈｃｖｎｓ３プロテアーゼのｐ１−非エピメリ化ケトアミド阻害剤
|
|
EP2160392A2
(en)
*
|
2007-05-03 |
2010-03-10 |
Intermune, Inc. |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
|
WO2008141227A1
(en)
|
2007-05-10 |
2008-11-20 |
Intermune, Inc. |
Novel peptide inhibitors of hepatitis c virus replication
|
|
CA2693997C
(en)
|
2007-08-03 |
2013-01-15 |
Pierre L. Beaulieu |
Viral polymerase inhibitors
|
|
AR068756A1
(es)
*
|
2007-10-10 |
2009-12-02 |
Novartis Ag |
Compuestos peptidicos, formulacion farmaceutica y sus usos como moduladores del virus de la hepatitis c
|
|
US8419332B2
(en)
*
|
2007-10-19 |
2013-04-16 |
Atlas Bolt & Screw Company Llc |
Non-dimpling fastener
|
|
CN101903351B
(zh)
|
2007-12-19 |
2014-09-10 |
贝林格尔.英格海姆国际有限公司 |
病毒聚合酶抑制剂
|
|
RU2490272C2
(ru)
|
2008-02-04 |
2013-08-20 |
Айденикс Фармасьютикалз, Инк. |
Макроциклические ингибиторы серинпротеазы
|
|
EA201071034A1
(ru)
|
2008-04-15 |
2011-06-30 |
Интермьюн, Инк. |
Новые макроциклические ингибиторы репликаций вируса гепатита с
|
|
JP2012514605A
(ja)
|
2009-01-07 |
2012-06-28 |
サイネクシス，インコーポレーテッド |
Ｈｃｖおよびｈｉｖ感染の治療への使用におけるシクロスポリン誘導体
|
|
US8102720B2
(en)
*
|
2009-02-02 |
2012-01-24 |
Qualcomm Incorporated |
System and method of pulse generation
|
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
|
JP5690286B2
(ja)
|
2009-03-04 |
2015-03-25 |
イデニク プハルマセウティカルス，インコーポレイテッド |
ホスホチオフェン及びホスホチアゾールｈｃｖポリメラーゼ阻害剤
|
|
WO2010118078A1
(en)
|
2009-04-08 |
2010-10-14 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors
|
|
US20110182850A1
(en)
*
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
|
JP2012528195A
(ja)
|
2009-05-29 |
2012-11-12 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Ｃ型肝炎などの疾患を処置するための３つの結合アリール部分で構成された抗菌性化合物
|
|
TW201117812A
(en)
|
2009-08-05 |
2011-06-01 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
|
EP2503881B1
(en)
|
2009-11-25 |
2015-05-13 |
Merck Sharp & Dohme Corp. |
Fused tricyclic compounds and derivatives thereof useful for the treatment of viral diseases
|
|
MX2012006877A
(es)
|
2009-12-18 |
2012-08-31 |
Idenix Pharmaceuticals Inc |
Inhibidores de virus de hepatitis c de arileno o heteroarileno 5, 5 - fusionado.
|
|
AU2010341537A1
(en)
|
2009-12-22 |
2012-08-09 |
Merck Sharp & Dohme Corp. |
Fused Tricyclic Compounds and methods of use thereof for the treatment of viral diseases
|
|
EP2545060B1
(en)
|
2010-03-09 |
2015-11-25 |
Merck Sharp & Dohme Corp. |
Fused tricyclic silyl compounds and methods of use thereof for the treatment of viral diseases
|
|
AU2011286276A1
(en)
|
2010-07-26 |
2013-01-24 |
Merck Sharp & Dohme Corp. |
Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases
|
|
JP2013540122A
(ja)
|
2010-09-29 |
2013-10-31 |
メルク・シャープ・エンド・ドーム・コーポレイション |
縮合四環式化合物誘導体およびウィルス疾患治療のためのそれの使用方法
|
|
JP5565320B2
(ja)
*
|
2011-01-06 |
2014-08-06 |
富士通株式会社 |
情報処理装置及び情報処理プログラム
|
|
US9353100B2
(en)
|
2011-02-10 |
2016-05-31 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
EP2697242B1
(en)
|
2011-04-13 |
2018-10-03 |
Merck Sharp & Dohme Corp. |
2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
BR112013026345A2
(pt)
|
2011-04-13 |
2019-04-24 |
Merck Sharp & Dohe Corp. |
composto, composição farmacêutica, uso de um composto, e, método para tratar um paciente infectado com hcv
|
|
WO2012158861A2
(en)
*
|
2011-05-18 |
2012-11-22 |
Enanta Pharmaceuticals, Inc. |
Processes for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives
|
|
WO2013033899A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
|
|
WO2013033901A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2013033900A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
|
|
EP2755981A4
(en)
|
2011-09-14 |
2015-03-25 |
Merck Sharp & Dohme |
SILICULAR HETEROCYCLIC DERIVATIVES AND METHOD FOR THEIR USE FOR THE TREATMENT OF VIRUS DISEASES
|
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
EP3063140A4
(en)
|
2013-10-30 |
2017-11-08 |
Merck Sharp & Dohme Corp. |
Pseudopolymorphs of an hcv ns5a inhibitor and uses thereof
|
|
WO2015134561A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
|
US20170066779A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
CN104292130B
(zh)
*
|
2014-10-13 |
2016-04-27 |
苏州永健生物医药有限公司 |
一种波普瑞韦中间体2-羟基-3-氨基-4-环丁基丁酰胺盐酸盐的合成方法
|
|
JP2023533016A
(ja)
|
2020-07-11 |
2023-08-01 |
ファイザー・インク |
抗ウイルス性ヘテロアリールケトン誘導体
|
|
US11351149B2
(en)
|
2020-09-03 |
2022-06-07 |
Pfizer Inc. |
Nitrile-containing antiviral compounds
|
|
US20240336610A1
(en)
*
|
2021-08-02 |
2024-10-10 |
The Global Health Drug Discovery Institute |
3cl protease small-molecule inhibitor for treating or preventing coronavirus infection, and use thereof
|