JP2007525521A5 - - Google Patents

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Publication number
JP2007525521A5
JP2007525521A5 JP2007501006A JP2007501006A JP2007525521A5 JP 2007525521 A5 JP2007525521 A5 JP 2007525521A5 JP 2007501006 A JP2007501006 A JP 2007501006A JP 2007501006 A JP2007501006 A JP 2007501006A JP 2007525521 A5 JP2007525521 A5 JP 2007525521A5
Authority
JP
Japan
Prior art keywords
compound
group
alkyl
hcv
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007501006A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007525521A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/006083 external-priority patent/WO2005085197A1/en
Publication of JP2007525521A publication Critical patent/JP2007525521A/ja
Publication of JP2007525521A5 publication Critical patent/JP2007525521A5/ja
Pending legal-status Critical Current

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JP2007501006A 2004-02-27 2005-02-24 Ｃ型肝炎ウイルスｎｓ３セリンプロテアーゼのインヒビターとしてのシクロブテンジオン基含有化合物 Pending JP2007525521A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54842304P 2004-02-27 2004-02-27
PCT/US2005/006083 WO2005085197A1 (en) 2004-02-27 2005-02-24 Cyclobutenedione groups-containing compounds as inhibitors of hepatitis c virus ns3 serine protease

Publications (2)

Publication Number Publication Date
JP2007525521A JP2007525521A (ja) 2007-09-06
JP2007525521A5 true JP2007525521A5 (https=) 2008-03-21

Family

ID=34919362

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007501006A Pending JP2007525521A (ja) 2004-02-27 2005-02-24 Ｃ型肝炎ウイルスｎｓ３セリンプロテアーゼのインヒビターとしてのシクロブテンジオン基含有化合物

Country Status (5)

Country Link
EP (1) EP1742914A1 (https=)
JP (1) JP2007525521A (https=)
CN (1) CN1946690A (https=)
CA (1) CA2557301A1 (https=)
WO (1) WO2005085197A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060281689A1 (en) * 2005-06-02 2006-12-14 Schering Corporation Method for modulating activity of HCV protease through use of a novel HCV protease inhibitor to reduce duration of treatment period
US20070021351A1 (en) * 2005-06-02 2007-01-25 Schering Corporation Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor
US20060275366A1 (en) * 2005-06-02 2006-12-07 Schering Corporation Controlled-release formulation
JP2008545748A (ja) * 2005-06-02 2008-12-18 シェーリング コーポレイション Ｃ型肝炎ウイルスに関連する障害を処置するために有用な徐放処方物
US20060276404A1 (en) * 2005-06-02 2006-12-07 Anima Ghosal Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
WO2006130554A2 (en) * 2005-06-02 2006-12-07 Schering Corporation Methods of treating hepatitis c virus
WO2006130552A2 (en) * 2005-06-02 2006-12-07 Schering Corporation Methods of treating hepatitis c virus
UA96283C2 (uk) 2005-12-23 2011-10-25 Зіланд Фарма А/С Модифіковані міметики лізину
US7816348B2 (en) 2006-02-03 2010-10-19 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
RU2009109355A (ru) 2006-08-17 2010-09-27 БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) Ингибиторы вырусной полимеразы
PL2468724T3 (pl) 2006-12-21 2016-05-31 Zealand Pharma As Synteza związków pirolidynowych
US8242140B2 (en) 2007-08-03 2012-08-14 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
EP2234977A4 (en) 2007-12-19 2011-04-13 Boehringer Ingelheim Int VIRAL POLYMERASE INHIBITORS
CN102271699A (zh) 2009-01-07 2011-12-07 西尼克斯公司 用于治疗hcv和hiv感染的环孢菌素衍生物
CN103387510B (zh) * 2013-08-08 2015-09-09 苏州永健生物医药有限公司 一种β-氨基-alpha-羟基环丁基丁酰胺盐酸盐的合成方法
JP6989864B2 (ja) 2017-05-05 2022-02-03 ジーランド ファーマ，アー／エス ギャップ結合細胞間コミュニケーションモジュレータ及び糖尿病性眼疾患の治療のためのそれらの使用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168103A (en) * 1991-01-22 1992-12-01 American Home Products Corporation [[2-(amino-3,4-dioxo-1-cyclobuten-1-yl) amino]alkyl]-acid derivatives
US6323180B1 (en) * 1998-08-10 2001-11-27 Boehringer Ingelheim (Canada) Ltd Hepatitis C inhibitor tri-peptides
UA74546C2 (en) * 1999-04-06 2006-01-16 Boehringer Ingelheim Ca Ltd Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
AU2001251165A1 (en) * 2000-04-03 2001-10-15 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
SK742003A3 (en) * 2000-07-21 2003-06-03 Schering Corp Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
US7244721B2 (en) * 2000-07-21 2007-07-17 Schering Corporation Peptides as NS3-serine protease inhibitors of hepatitis C virus
CN1498224A (zh) * 2000-07-21 2004-05-19 ���鹫˾ 用作丙型肝炎病毒ns3-丝氨酸蛋白酶抑制剂的新型肽
WO2002062761A1 (en) * 2001-02-07 2002-08-15 Abbott Laboratories Aminal diones as potassium channel openers
US20040106794A1 (en) * 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
PL208928B1 (pl) * 2001-04-16 2011-06-30 Pharmacopeia 3, 4-di-podstawione cyklobuten-1, 2-diony jako ligandy receptora CXC chemokiny

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