JP2007512018A - 乳酸産生酵母 - Google Patents

乳酸産生酵母 Download PDF

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Publication number
JP2007512018A
JP2007512018A JP2006541344A JP2006541344A JP2007512018A JP 2007512018 A JP2007512018 A JP 2007512018A JP 2006541344 A JP2006541344 A JP 2006541344A JP 2006541344 A JP2006541344 A JP 2006541344A JP 2007512018 A JP2007512018 A JP 2007512018A
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yeast strain
liter
lactic acid
lactate dehydrogenase
carbon source
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JP2007512018A5 (https=
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チー‐リー、リウ
ジェファーソン、シー．リーベンス
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2006541344A 2003-11-20 2004-11-17 乳酸産生酵母 Withdrawn JP2007512018A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/717,993 US20050112737A1 (en) 2003-11-20 2003-11-20 Lactic acid producing yeast
PCT/US2004/038548 WO2005052174A2 (en) 2003-11-20 2004-11-17 Lactic acid producing yeast

Publications (2)

Publication Number Publication Date
JP2007512018A true JP2007512018A (ja) 2007-05-17
JP2007512018A5 JP2007512018A5 (https=) 2007-12-13

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JP2006541344A Withdrawn JP2007512018A (ja) 2003-11-20 2004-11-17 乳酸産生酵母

Country Status (7)

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US (1) US20050112737A1 (https=)
EP (1) EP1689873A2 (https=)
JP (1) JP2007512018A (https=)
CN (1) CN1902319A (https=)
AU (1) AU2004293781A1 (https=)
BR (1) BRPI0416220A (https=)
WO (1) WO2005052174A2 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006020602A (ja) * 2004-07-09 2006-01-26 Toyota Central Res & Dev Lab Inc 乳酸生産方法
JPWO2010001862A1 (ja) * 2008-06-30 2011-12-22 トヨタ自動車株式会社 有機酸の製造方法
JPWO2011021629A1 (ja) * 2009-08-21 2013-01-24 旭硝子株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法
WO2015076393A1 (ja) 2013-11-22 2015-05-28 旭硝子株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法
US9428777B2 (en) 2012-08-24 2016-08-30 Asahi Glass Company, Limited Transformant and method for producing same, and method for producing lactic acid
US10214754B2 (en) 2014-10-10 2019-02-26 Jmtc Enzyme Corporation Transformant and its production process, and method for producing lactic acid

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) * 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US20070031950A1 (en) * 1998-09-11 2007-02-08 Winkler Aaron A Production of D-lactic acid with yeast
DK2305826T3 (en) 2005-08-10 2016-06-27 Univ Florida Materials and methods for the efficient production of lactic acid
JP2007061024A (ja) * 2005-08-31 2007-03-15 Neo-Morgan Laboratory Inc 乳酸耐性に優れた生物および乳酸耐性に優れた生物の作製方法
WO2007038130A2 (en) * 2005-09-22 2007-04-05 Tate & Lyle Ingredients Americas, Inc. Improved strains for the production of organic acids
US20100317073A1 (en) * 2007-12-04 2010-12-16 The Ohio State University Research Foundation Molecular approaches for the optimization of biofuel production
KR101483470B1 (ko) 2008-02-04 2015-01-16 도레이 카부시키가이샤 연속 발효에 의한 유산의 제조방법
CN101983242B (zh) * 2008-02-06 2015-12-16 拜康有限公司 含有尿素类氮源的发酵培养基及其用于生产重组蛋白的用途
WO2009115114A1 (en) * 2008-03-18 2009-09-24 Metabolic Explorer Polypeptide having glyoxylase iii activity, polynucleotide encoding the same and uses thereof
EP2128262A1 (en) 2008-05-28 2009-12-02 Università Degli Studi Di Milano - Bicocca Improved yeast strains for organic acid production
CN102575235B (zh) 2009-07-30 2015-05-20 代谢探索者公司 用于通过发酵生产生物化学品的突变甲基乙二醛合酶(mgs)
WO2011026008A1 (en) * 2009-08-28 2011-03-03 Phycal Llc Biofuel from recombinant oleginous algae using sugar carbon sources
US9012190B2 (en) 2011-06-15 2015-04-21 Butamax Advanced Biofuels Llc Use of thiamine and nicotine adenine dinucleotide for butanol production
CN103392004A (zh) * 2011-02-21 2013-11-13 旭硝子株式会社 乳酸的制造方法
CN102212489A (zh) * 2011-04-13 2011-10-12 江南大学 一种高产乳酸的酿酒酵母工程菌的构建及其应用
CN102199553B (zh) * 2011-05-06 2012-07-11 江南大学 一株耐酸酵母及其代谢工程构建产l-乳酸重组菌的方法
BR112014027543B1 (pt) * 2012-05-22 2022-01-18 Toray Industries, Inc Método para a produção de ácido lático e método para a produção de ácido polilático
KR101576186B1 (ko) * 2012-06-26 2015-12-10 한국생명공학연구원 에탄올 생산 경로가 봉쇄된 클루이베로마이세스 막시아누스 균주 및 이의 용도
CN102715235B (zh) * 2012-07-10 2013-09-11 武汉光明乳品有限公司 一种活性植物乳杆菌饮品及其制备方法
CA2888223A1 (en) * 2012-10-17 2014-04-24 The Coca-Cola Company Compositions and methods for reduced carbohydrates and increased erythritol in beverages
RU2539092C1 (ru) * 2013-09-27 2015-01-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") РЕКОМБИНАНТНЫЙ ШТАММ ДРОЖЖЕЙ Schizosaccharomyces pombe - ПРОДУЦЕНТ МОЛОЧНОЙ КИСЛОТЫ
KR20150065213A (ko) 2013-12-04 2015-06-15 삼성전자주식회사 감소된 에탄올 생산능을 갖는 효모 세포 및 이의 용도
KR101577134B1 (ko) * 2014-05-09 2015-12-14 씨제이제일제당 (주) 젖산 생산이 향상된 미생물 및 이를 이용하여 젖산을 생산하는 방법
CN104031948A (zh) * 2014-06-26 2014-09-10 华东理工大学 利用海洋真菌生产免疫抑制化合物的方法及其培养基
BR112017000424A2 (pt) * 2014-07-10 2018-01-23 Archer Daniels Midland Co método de recuperação de lactato de etila a partir de um processo de fermentação de ácido láctico
KR101704212B1 (ko) * 2015-06-12 2017-02-08 씨제이제일제당 (주) 젖산을 생산하는 미생물 및 이를 이용한 젖산 제조 방법
CN104911118A (zh) * 2015-06-29 2015-09-16 江南大学 一种乳酸脱氢酶人源化酿酒酵母及其构建方法
KR102311681B1 (ko) * 2015-07-28 2021-10-12 삼성전자주식회사 내산성을 갖는 효모 세포, 그를 이용하여 유기산을 생산하는 방법 및 상기 내산성 효모 세포를 생산하는 방법
RU2614233C1 (ru) * 2015-12-22 2017-03-23 Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГБУ "ГосНИИгенетика") Трансформант дрожжей Schizosaccharomyces pombe, продуцирующий молочную кислоту (варианты), способ его получения (варианты), способ микробиологического синтеза молочной кислоты с использованием такого трансформанта
KR102140596B1 (ko) 2018-04-17 2020-08-04 에스케이이노베이션 주식회사 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법
KR102736070B1 (ko) 2018-10-08 2024-12-02 에스케이이노베이션 주식회사 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
CN110845025B (zh) * 2019-09-11 2021-12-28 呼伦贝尔东北阜丰生物科技有限公司 利用复合菌剂降解氨基酸发酵废液中有机质的工艺
KR20210041903A (ko) 2019-10-08 2021-04-16 에스케이이노베이션 주식회사 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210128742A (ko) 2020-04-17 2021-10-27 에스케이이노베이션 주식회사 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210158676A (ko) 2020-06-24 2021-12-31 에스케이이노베이션 주식회사 젖산 생산능이 증가된 재조합 내산성 효모
CN116555062B (zh) * 2023-03-17 2023-10-27 江南大学 基于乙醇代谢流调控提升酿酒酵母生产l-乳酸的方法
CN116855464A (zh) * 2023-07-27 2023-10-10 北京首医临床医学科技有限公司 一种利用酵母菌发酵生产乳酸脱氢酶的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2024565A (en) * 1931-10-29 1935-12-17 Standard Brands Inc Process for the production of lactic acid
US4885247A (en) * 1988-04-19 1989-12-05 Michigan Biotechnology Institute Recovery and purification of lactate salts from whole fermentation broth by electrodialysis
US5068418A (en) * 1989-05-08 1991-11-26 Uop Separation of lactic acid from fermentation broth with an anionic polymeric absorbent
US5464760A (en) * 1990-04-04 1995-11-07 University Of Chicago Fermentation and recovery process for lactic acid production
TW211560B (https=) * 1991-03-14 1993-08-21 Peilly Ind Inc
AT398982B (de) * 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US6187951B1 (en) * 1993-06-29 2001-02-13 Cargill, Incorporated Lactic acid production, separation and/or recovery process
US5510526A (en) * 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
US6001255A (en) * 1993-07-12 1999-12-14 Eyal; Aharon Process for the production of water-soluble salts of carboxylic and amino acids
US5503750A (en) * 1993-10-04 1996-04-02 Russo, Jr.; Lawrence J. Membrane-based process for the recovery of lactic acid by fermentation of carbohydrate substrates containing sugars
US6060173A (en) * 1996-04-17 2000-05-09 Englehard Corporation Metal honeycomb body
NZ336852A (en) * 1996-12-23 2000-06-23 Lactascan Aps Production of lactic acid from whey proteins where electrodialysis causes less biofouling of the electrodialysis membrane
BE1011197A3 (fr) * 1997-06-06 1999-06-01 Brussels Biotech En Abrege Bb Procede de purification d'acide lactique.
IT1294728B1 (it) * 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US6229046B1 (en) * 1997-10-14 2001-05-08 Cargill, Incorported Lactic acid processing methods arrangements and products
US6475759B1 (en) * 1997-10-14 2002-11-05 Cargill, Inc. Low PH lactic acid fermentation
US6485947B1 (en) * 1999-05-21 2002-11-26 Cargill Dow Polymers, Llc Production of lactate using crabtree negative organisms in varying culture conditions
FR2799754A1 (fr) * 1999-10-18 2001-04-20 Roquette Freres Procede de separation et de purification d'acide lactique a partir d'un milieu de fermentation
US6268189B1 (en) * 2000-03-24 2001-07-31 The United States Of America As Represented By The Secretary Of Agriculture Fungal lactate dehydrogenase gene and constructs for the expression thereof
EP1513939B1 (en) * 2002-05-30 2014-12-31 Cargill Inc. Fermentation process using specific oxygen uptake rates as a process control

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006020602A (ja) * 2004-07-09 2006-01-26 Toyota Central Res & Dev Lab Inc 乳酸生産方法
JPWO2010001862A1 (ja) * 2008-06-30 2011-12-22 トヨタ自動車株式会社 有機酸の製造方法
JPWO2011021629A1 (ja) * 2009-08-21 2013-01-24 旭硝子株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法
US9284561B2 (en) 2009-08-21 2016-03-15 Asahi Glass Company, Limited Transformant and process for production thereof, and process for production of lactic acid
US9428777B2 (en) 2012-08-24 2016-08-30 Asahi Glass Company, Limited Transformant and method for producing same, and method for producing lactic acid
WO2015076393A1 (ja) 2013-11-22 2015-05-28 旭硝子株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法
US10597662B2 (en) 2013-11-22 2020-03-24 Jmtc Enzyme Corporation Transformant and process for production thereof, and process for production of lactic acid
US10214754B2 (en) 2014-10-10 2019-02-26 Jmtc Enzyme Corporation Transformant and its production process, and method for producing lactic acid

Also Published As

Publication number Publication date
US20050112737A1 (en) 2005-05-26
EP1689873A2 (en) 2006-08-16
BRPI0416220A (pt) 2007-01-02
AU2004293781A1 (en) 2005-06-09
WO2005052174A3 (en) 2005-11-24
CN1902319A (zh) 2007-01-24
WO2005052174A2 (en) 2005-06-09

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