|
ATE75483T1
(de)
|
1981-10-23 |
1992-05-15 |
Molecular Biosystems Inc |
Oligonukleotides heilmittel und dessen herstellungsverfahren.
|
|
US4541087A
(en)
*
|
1983-06-27 |
1985-09-10 |
Confertech International, Inc. |
Digital teleconferencing control device, system and method
|
|
CA1339596C
(en)
|
1987-08-07 |
1997-12-23 |
New England Medical Center Hospitals, Inc. |
Viral expression inhibitors
|
|
US4958013A
(en)
*
|
1989-06-06 |
1990-09-18 |
Northwestern University |
Cholesteryl modified oligonucleotides
|
|
US5399676A
(en)
|
1989-10-23 |
1995-03-21 |
Gilead Sciences |
Oligonucleotides with inverted polarity
|
|
EP0468520A3
(en)
|
1990-07-27 |
1992-07-01 |
Mitsui Toatsu Chemicals, Inc. |
Immunostimulatory remedies containing palindromic dna sequences
|
|
EP0652890B1
(en)
|
1992-07-27 |
1998-01-14 |
HYBRIDON, Inc. |
Oligonucleotide alkylphosphonothioates
|
|
US5558988A
(en)
*
|
1992-11-13 |
1996-09-24 |
Thomas Jefferson University |
Primers and methods for detecting mutations in the procollagen II gene that indicate a genetic predisposition for osteoarthritis
|
|
US6605708B1
(en)
|
1993-07-28 |
2003-08-12 |
Hybridon, Inc. |
Building blocks with carbamate internucleoside linkages and oligonucleotides derived therefrom
|
|
DE4338704A1
(de)
|
1993-11-12 |
1995-05-18 |
Hoechst Ag |
Stabilisierte Oligonucleotide und deren Verwendung
|
|
US5646126A
(en)
|
1994-02-28 |
1997-07-08 |
Epoch Pharmaceuticals |
Sterol modified oligonucleotide duplexes having anticancer activity
|
|
US5596091A
(en)
|
1994-03-18 |
1997-01-21 |
The Regents Of The University Of California |
Antisense oligonucleotides comprising 5-aminoalkyl pyrimidine nucleotides
|
|
US6727230B1
(en)
|
1994-03-25 |
2004-04-27 |
Coley Pharmaceutical Group, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
US20030050263A1
(en)
|
1994-07-15 |
2003-03-13 |
The University Of Iowa Research Foundation |
Methods and products for treating HIV infection
|
|
US7935675B1
(en)
|
1994-07-15 |
2011-05-03 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6429199B1
(en)
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
|
US20030026782A1
(en)
|
1995-02-07 |
2003-02-06 |
Arthur M. Krieg |
Immunomodulatory oligonucleotides
|
|
JP3468773B2
(ja)
|
1994-07-15 |
2003-11-17 |
ザ ユニバーシティ オブ アイオワ リサーチ ファウンデーション |
免疫調節オリゴヌクレオチド
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6207646B1
(en)
*
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
DE19502912A1
(de)
|
1995-01-31 |
1996-08-01 |
Hoechst Ag |
G-Cap Stabilisierte Oligonucleotide
|
|
US5968909A
(en)
|
1995-08-04 |
1999-10-19 |
Hybridon, Inc. |
Method of modulating gene expression with reduced immunostimulatory response
|
|
US5780448A
(en)
|
1995-11-07 |
1998-07-14 |
Ottawa Civic Hospital Loeb Research |
DNA-based vaccination of fish
|
|
US7432048B2
(en)
*
|
1996-11-29 |
2008-10-07 |
Third Wave Technologies, Inc. |
Reactions on a solid surface
|
|
US6030955A
(en)
*
|
1996-03-21 |
2000-02-29 |
The Trustees Of Columbia University In The City Of New York And Imclone Systems, Inc. |
Methods of affecting intracellular phosphorylation of tyrosine using phosphorothioate oligonucleotides, and antiangiogenic and antiproliferative uses thereof
|
|
US5856462A
(en)
|
1996-09-10 |
1999-01-05 |
Hybridon Incorporated |
Oligonucleotides having modified CpG dinucleosides
|
|
ES2241042T3
(es)
|
1996-10-11 |
2005-10-16 |
The Regents Of The University Of California |
Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora.
|
|
EP0855184A1
(en)
*
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
|
EP1039935A4
(en)
|
1997-02-28 |
2005-04-27 |
Univ Iowa Res Found |
USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS
|
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6426334B1
(en)
|
1997-04-30 |
2002-07-30 |
Hybridon, Inc. |
Oligonucleotide mediated specific cytokine induction and reduction of tumor growth in a mammal
|
|
US6835395B1
(en)
|
1997-05-14 |
2004-12-28 |
The University Of British Columbia |
Composition containing small multilamellar oligodeoxynucleotide-containing lipid vesicles
|
|
US6339068B1
(en)
|
1997-05-20 |
2002-01-15 |
University Of Iowa Research Foundation |
Vectors and methods for immunization or therapeutic protocols
|
|
US20040006034A1
(en)
|
1998-06-05 |
2004-01-08 |
Eyal Raz |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
US6589940B1
(en)
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
ATE432348T1
(de)
|
1997-06-06 |
2009-06-15 |
Univ California |
Inhibitoren von immunstimulatorischen dna sequenz aktivität
|
|
ATE408422T1
(de)
|
1997-07-03 |
2008-10-15 |
Donald E Macfarlane |
Methode zur hemmung immunstimulatorischer mit dna assoziierter antworten
|
|
DE19750702A1
(de)
*
|
1997-11-15 |
1999-05-27 |
Hoechst Marion Roussel De Gmbh |
Antisense Oligonucleotide gegen Tenascin zur Behandlung von Vitiligo
|
|
US7393630B2
(en)
*
|
1997-12-16 |
2008-07-01 |
Novartis Vaccines And Diagnostics, Inc. |
Use of microparticles combined with submicron oil-in-water emulsions
|
|
CA2323929C
(en)
|
1998-04-03 |
2004-03-09 |
University Of Iowa Research Foundation |
Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines
|
|
ATE302269T1
(de)
*
|
1998-04-14 |
2005-09-15 |
Sugen Inc |
Ste20-verwandte proteinkinasen
|
|
EP1595946A3
(en)
*
|
1998-04-14 |
2006-01-11 |
Sugen, Inc. |
STE20-related protein kinases
|
|
JP2002513763A
(ja)
|
1998-05-06 |
2002-05-14 |
ユニバーシティ オブ アイオワ リサーチ ファウンデーション |
Cpgオリゴヌクレオチドを使用して寄生生物感染および関連する疾患を予防および処置するための方法
|
|
NZ508650A
(en)
|
1998-05-14 |
2003-05-30 |
Coley Pharm Gmbh |
Regulating hematopoiesis using unmethylated C and G CpG-oligonucleotides with a phosphorothioate modification
|
|
ES2272069T3
(es)
|
1998-05-22 |
2007-04-16 |
Ottawa Health Research Institute |
Metodos y productos para inducir inmunidad en mucosas.
|
|
US6562798B1
(en)
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
|
WO2000006588A1
(en)
|
1998-07-27 |
2000-02-10 |
University Of Iowa Research Foundation |
STEREOISOMERS OF CpG OLIGONUCLEOTIDES AND RELATED METHODS
|
|
ATE507297T1
(de)
*
|
1998-08-20 |
2011-05-15 |
Du Pont |
Gene für fettsäuremodfizierende enzyme von planzen und damit verbundene bildung von konjugierten doppelbindungen
|
|
FR2783170B1
(fr)
|
1998-09-11 |
2004-07-16 |
Pasteur Merieux Serums Vacc |
Emulsion immunostimulante
|
|
AU1915500A
(en)
*
|
1998-11-20 |
2000-06-13 |
Bristol-Myers Squibb Company |
Water soluble prodrugs of azole compounds
|
|
US6207819B1
(en)
|
1999-02-12 |
2001-03-27 |
Isis Pharmaceuticals, Inc. |
Compounds, processes and intermediates for synthesis of mixed backbone oligomeric compounds
|
|
WO2000054803A2
(en)
|
1999-03-16 |
2000-09-21 |
Panacea Pharmaceuticals, Llc |
Immunostimulatory nucleic acids and antigens
|
|
US6977245B2
(en)
*
|
1999-04-12 |
2005-12-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
|
WO2000061151A2
(en)
*
|
1999-04-12 |
2000-10-19 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
|
EP1377554A1
(en)
|
1999-06-16 |
2004-01-07 |
University Of Iowa Research Foundation |
Antagonism of immunostimulatory cpg-oligonucleotides by 4-aminoquinolines and other weak bases
|
|
US6514948B1
(en)
|
1999-07-02 |
2003-02-04 |
The Regents Of The University Of California |
Method for enhancing an immune response
|
|
DE19935756A1
(de)
|
1999-07-27 |
2001-02-08 |
Mologen Forschungs Entwicklung |
Kovalent geschlossenes Nukleinsäuremolekül zur Immunstimulation
|
|
DE19935302A1
(de)
*
|
1999-07-28 |
2001-02-08 |
Aventis Pharma Gmbh |
Konjugate und Verfahren zu deren Herstellung sowie deren Verwendung zum Transport von Molekülen über biologische Membranen
|
|
US6822086B1
(en)
*
|
1999-08-09 |
2004-11-23 |
The General Hospital Corporation |
Drug-carrier complexes and methods of use thereof
|
|
DE60017259T2
(de)
|
1999-08-13 |
2005-12-08 |
Hybridon, Inc., Cambridge |
Modulation der CPG-Oligonukleotid-vermittelten Immunstimulation durch Positionsbedingte Modifikation von Nukleosiden
|
|
SK287400B6
(sk)
|
1999-09-25 |
2010-08-09 |
University Of Iowa Research Foundation |
Prostriedok s obsahom imunostimulačnej nukleovej kyseliny a jeho použitie na stimuláciu imunitnej reakcie
|
|
US6949520B1
(en)
*
|
1999-09-27 |
2005-09-27 |
Coley Pharmaceutical Group, Inc. |
Methods related to immunostimulatory nucleic acid-induced interferon
|
|
DE60131430T2
(de)
*
|
2000-01-14 |
2008-10-16 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion
|
|
CA2396871A1
(en)
|
2000-01-20 |
2001-12-20 |
Ottawa Health Research Institute |
Immunostimulatory nucleic acids for inducing a th2 immune response
|
|
AU783687B2
(en)
|
2000-01-26 |
2005-11-24 |
Idera Pharmaceuticals, Inc. |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
|
|
US7585847B2
(en)
|
2000-02-03 |
2009-09-08 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory nucleic acids for the treatment of asthma and allergy
|
|
US20020156033A1
(en)
|
2000-03-03 |
2002-10-24 |
Bratzler Robert L. |
Immunostimulatory nucleic acids and cancer medicament combination therapy for the treatment of cancer
|
|
US20040131628A1
(en)
|
2000-03-08 |
2004-07-08 |
Bratzler Robert L. |
Nucleic acids for the treatment of disorders associated with microorganisms
|
|
JP3585420B2
(ja)
*
|
2000-04-20 |
2004-11-04 |
株式会社椿本チエイン |
チェーン用巻き加工品及びその製造方法
|
|
AU2001259706A1
(en)
|
2000-05-09 |
2001-11-20 |
Reliable Biopharmaceutical, Inc. |
Polymeric compounds useful as prodrugs
|
|
US6339630B1
(en)
*
|
2000-05-18 |
2002-01-15 |
The United States Of America As Represented By The United States Department Of Energy |
Sealed drive screw operator
|
|
ATE440618T1
(de)
|
2000-06-22 |
2009-09-15 |
Univ Iowa Res Found |
Kombination von cpg und antikírpern gegen cd19, cd20,cd22 oder cd40 zur prävention oder behandlung von krebs.
|
|
US20020165178A1
(en)
|
2000-06-28 |
2002-11-07 |
Christian Schetter |
Immunostimulatory nucleic acids for the treatment of anemia, thrombocytopenia, and neutropenia
|
|
US20020198165A1
(en)
|
2000-08-01 |
2002-12-26 |
Bratzler Robert L. |
Nucleic acids for the prevention and treatment of gastric ulcers
|
|
US20020091097A1
(en)
|
2000-09-07 |
2002-07-11 |
Bratzler Robert L. |
Nucleic acids for the prevention and treatment of sexually transmitted diseases
|
|
US6943240B2
(en)
|
2000-09-15 |
2005-09-13 |
Coley Pharmaceuticals Gmbh |
Nucleic acids for high throughput screening of CpG-based immuno-agonist/antagonist
|
|
EP1322656B1
(en)
|
2000-09-26 |
2008-01-16 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
|
|
FR2814958B1
(fr)
|
2000-10-06 |
2003-03-07 |
Aventis Pasteur |
Composition vaccinale
|
|
GB0025577D0
(en)
|
2000-10-18 |
2000-12-06 |
Smithkline Beecham Biolog |
Vaccine
|
|
ES2307568T3
(es)
|
2000-12-08 |
2008-12-01 |
Coley Pharmaceutical Gmbh |
Acidos nucleicos de tipo cpg y metodos de uso de los mismos.
|
|
US20030055014A1
(en)
|
2000-12-14 |
2003-03-20 |
Bratzler Robert L. |
Inhibition of angiogenesis by nucleic acids
|
|
US20030050268A1
(en)
|
2001-03-29 |
2003-03-13 |
Krieg Arthur M. |
Immunostimulatory nucleic acid for treatment of non-allergic inflammatory diseases
|
|
US20030052063A1
(en)
*
|
2001-03-30 |
2003-03-20 |
Motoaki Sakashita |
Decontamination method and apparatus
|
|
US7713942B2
(en)
|
2001-04-04 |
2010-05-11 |
Nordic Vaccine Technology A/S |
Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
|
|
US7105495B2
(en)
|
2001-04-30 |
2006-09-12 |
Idera Pharmaceuticals, Inc. |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
|
|
US7785610B2
(en)
*
|
2001-06-21 |
2010-08-31 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same—III
|
|
US20040132677A1
(en)
|
2001-06-21 |
2004-07-08 |
Fearon Karen L. |
Chimeric immunomodulatory compounds and methods of using the same-IV
|
|
DK2423335T3
(da)
|
2001-06-21 |
2014-08-18 |
Dynavax Tech Corp |
Kimæriske immunmodulatoriske forbindelser og fremgangsmåder til anvendelse deraf
|
|
US6893572B2
(en)
*
|
2001-07-12 |
2005-05-17 |
Western Environmental Engineering Company |
Solids accumulating flotation separator
|
|
WO2003040308A2
(en)
*
|
2001-07-27 |
2003-05-15 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of sterically stabilized cationic liposomes to efficiently deliver cpg oligonucleotides in vivo
|
|
US7666674B2
(en)
*
|
2001-07-27 |
2010-02-23 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo
|
|
AU2002318944A1
(en)
|
2001-08-01 |
2003-02-17 |
Coley Pharmaceutical Gmbh |
Methods and compositions relating to plasmacytoid dendritic cells
|
|
WO2003020884A2
(en)
*
|
2001-08-14 |
2003-03-13 |
The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services |
Method for rapid generation of mature dendritic cells
|
|
IL160157A0
(en)
|
2001-08-17 |
2004-07-25 |
Coley Pharm Group Inc |
Combination motif immune stimulation oligonucleotides with improved activity
|
|
US20040259153A1
(en)
*
|
2001-08-22 |
2004-12-23 |
Yoshikazu Kurosawa |
Methods for selecting biding molecule
|
|
CA2461877A1
(en)
|
2001-09-28 |
2003-04-10 |
Purdue Research Foundation |
Method of treatment using ligand-immunogen conjugates
|
|
IL160837A0
(en)
|
2001-10-05 |
2004-08-31 |
Coley Pharm Gmbh |
Toll-like receptor 3 signaling agonists and antagonists
|
|
US20030139364A1
(en)
|
2001-10-12 |
2003-07-24 |
University Of Iowa Research Foundation |
Methods and products for enhancing immune responses using imidazoquinoline compounds
|
|
WO2003035836A2
(en)
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
|
US7276489B2
(en)
*
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
|
AU2002366710A1
(en)
*
|
2001-12-20 |
2003-07-09 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of |
USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS
|
|
CA2474709A1
(en)
|
2002-02-04 |
2003-08-14 |
Biomira, Inc. |
Immunostimulatory, covalently lipidated oligonucleotides
|
|
EP1499187B1
(en)
|
2002-04-04 |
2015-06-17 |
Zoetis Belgium S.A. |
Immunostimulatory g,u-containing oligoribonucleotides
|
|
CA2483012C
(en)
|
2002-04-22 |
2011-05-24 |
Bioniche Life Sciences Inc. |
Oligonucleotide compositions and their use for the modulation of immune responses
|
|
EP1503793A2
(en)
|
2002-05-10 |
2005-02-09 |
Inex Pharmaceuticals Corp. |
Cancer vaccines and methods of using the same
|
|
WO2003103586A2
(en)
|
2002-06-05 |
2003-12-18 |
Coley Pharmaceutical Group, Inc. |
Method for treating autoimmune or inflammatory diseases with combinations of inhibitory oligonucleotides and small molecule antagonists of immunostimulatory cpg nucleic acids
|
|
US7576066B2
(en)
|
2002-07-03 |
2009-08-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7807803B2
(en)
|
2002-07-03 |
2010-10-05 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7605138B2
(en)
|
2002-07-03 |
2009-10-20 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US20040053880A1
(en)
|
2002-07-03 |
2004-03-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7569553B2
(en)
|
2002-07-03 |
2009-08-04 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
AU2003255969A1
(en)
|
2002-07-17 |
2004-02-02 |
Coley Pharmaceutical Gmbh |
Use of cpg nucleic acids in prion-disease
|
|
CN100471486C
(zh)
*
|
2002-08-12 |
2009-03-25 |
戴纳伐克斯技术股份有限公司 |
免疫调节组合物,其制备方法和使用方法
|
|
AR040996A1
(es)
|
2002-08-19 |
2005-04-27 |
Coley Pharm Group Inc |
Acidos nucleicos inmunoestimuladores
|
|
US8043622B2
(en)
*
|
2002-10-08 |
2011-10-25 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of treating inflammatory lung disease with suppressors of CpG oligonucleotides
|
|
EA008777B1
(ru)
*
|
2002-10-29 |
2007-08-31 |
Коли Фармасьютикал Груп, Лтд. |
Способы и продукты, относящиеся к лечению и предупреждению инфекции вируса гепатита c
|
|
WO2004098491A2
(en)
*
|
2002-11-01 |
2004-11-18 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
METHOD OF PREVENTING INFECTIONS FROM BIOTERRORISM AGENTS WITH IMMUNOSTIMULATORY CpG OLIGONUCLEOTIDES
|
|
US7956043B2
(en)
|
2002-12-11 |
2011-06-07 |
Coley Pharmaceutical Group, Inc. |
5′ CpG nucleic acids and methods of use
|
|
CA2508985A1
(en)
|
2002-12-23 |
2004-07-15 |
Dynavax Technologies Corporation |
Branched immunomodulatory compounds and methods of using the same
|
|
AU2004206820B2
(en)
|
2003-01-16 |
2010-06-10 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides
|
|
CA2521050A1
(en)
*
|
2003-04-02 |
2004-10-14 |
Coley Pharmaceutical Group, Ltd. |
Immunostimulatory nucleic acid oil-in-water formulations and related methods of use
|
|
WO2004094671A2
(en)
|
2003-04-22 |
2004-11-04 |
Coley Pharmaceutical Gmbh |
Methods and products for identification and assessment of tlr ligands
|
|
EP1631576A4
(en)
*
|
2003-06-11 |
2010-08-25 |
Idera Pharmaceuticals Inc |
STABILIZED IMMUNOMODULATION OLIGONUCLEOTIDES
|
|
EP1635846A4
(en)
|
2003-06-20 |
2009-01-28 |
Coley Pharm Gmbh |
SMALL MOLECULAR TLR (TOLL-LIKE RECEPTOR) ANTAGONISTS
|
|
AU2004259204B2
(en)
|
2003-07-15 |
2010-08-19 |
Idera Pharmaceuticals, Inc. |
Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
|
|
WO2005025583A2
(en)
*
|
2003-09-05 |
2005-03-24 |
Anadys Pharmaceuticals, Inc. |
Tlr7 ligands for the treatment of hepatitis c
|
|
CA2536139A1
(en)
*
|
2003-09-25 |
2005-04-07 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid-lipophilic conjugates
|
|
US20050215501A1
(en)
|
2003-10-24 |
2005-09-29 |
Coley Pharmaceutical Group, Inc. |
Methods and products for enhancing epitope spreading
|
|
NZ546475A
(en)
*
|
2003-10-30 |
2008-08-29 |
Coley Pharm Gmbh |
C-Class oligonucleotide analogs with enhanced immunostimulatory potency
|
|
US20050100983A1
(en)
|
2003-11-06 |
2005-05-12 |
Coley Pharmaceutical Gmbh |
Cell-free methods for identifying compounds that affect toll-like receptor 9 (TLR9) signaling
|
|
CN101094594B
(zh)
|
2003-12-08 |
2012-08-15 |
海布里顿公司 |
通过基于小寡核苷酸的化合物调节免疫刺激性质
|
|
AU2005326144A1
(en)
*
|
2004-06-08 |
2006-08-03 |
Coley Pharmaceutical Gmbh |
Abasic oligonucleotide as carrier platform for antigen and immunostimulatory agonist and antagonist
|
|
HRP20070012A2
(hr)
|
2004-06-15 |
2007-10-31 |
Idera Pharmaceuticals |
Imunostimulatorski oligonukleotidni multimeri
|
|
EP1776105A2
(en)
*
|
2004-07-18 |
2007-04-25 |
Coley Pharmaceutical Group, Ltd |
Methods and compositions for inducing innate immune responses
|
|
MY159370A
(en)
*
|
2004-10-20 |
2016-12-30 |
Coley Pharm Group Inc |
Semi-soft-class immunostimulatory oligonucleotides
|
|
US20080003232A1
(en)
*
|
2004-11-29 |
2008-01-03 |
Liying Wang |
Cpg Single Strand Deoxynucleotides for Use as Adjuvant
|
|
CN1810970B
(zh)
*
|
2005-01-27 |
2011-05-18 |
长春华普生物技术有限公司 |
含CpG的单链脱氧核苷酸与其疫苗组合物及其应用
|
|
CN1847256B
(zh)
*
|
2005-04-13 |
2011-06-15 |
长春华普生物技术有限公司 |
含CpG单链脱氧寡核苷酸和利巴韦林联合应用产生的抗病毒作用
|
|
US7792535B2
(en)
*
|
2005-05-31 |
2010-09-07 |
Alcatel-Lucent Usa Inc. |
Enhanced mobile station paging in a wireless telecommunications network
|
|
KR20080030656A
(ko)
*
|
2005-07-07 |
2008-04-04 |
콜레이 파마시티컬 그룹, 인코포레이티드 |
암 치료를 위한 항-CTLA-4 항체 및 CpG-모티프-함유합성 올리고데옥시뉴클레오티드의 조합 요법
|
|
US7965675B2
(en)
*
|
2005-08-22 |
2011-06-21 |
Motorola Mobility, Inc. |
System and method for detecting an unlicensed mobile alliance (UMA) service in GSM wireless communication networks
|
|
JP5481068B2
(ja)
*
|
2005-08-31 |
2014-04-23 |
アメリカ合衆国 |
CpGオリゴデオキシヌクレオチドによって誘発される免疫応答を変化させる方法
|
|
US8399423B2
(en)
*
|
2005-10-12 |
2013-03-19 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
ES2536103T3
(es)
*
|
2005-11-25 |
2015-05-20 |
Zoetis Belgium S.A. |
Oligorribonucleótidos inmunoestimuladores
|
|
JP5473336B2
(ja)
*
|
2006-02-15 |
2014-04-16 |
アディウタイド・ファーマスーティカルズ・ゲーエムベーハー |
オリゴヌクレオチドの処方に関する組成物および方法
|
|
JP5761911B2
(ja)
*
|
2006-04-07 |
2015-08-12 |
イデラ ファーマシューティカルズ インコーポレイテッドIdera Pharmaceuticals, Inc. |
Tlr7およびtlr8に対する安定化免疫調節rna(simra)化合物
|
|
MX2009003398A
(es)
*
|
2006-09-27 |
2009-08-12 |
Coley Pharm Gmbh |
Analogos de oligonucleotidos cpg que contienen analogos t hidrofobos con actividad inmunoestimuladora mejorada.
|
|
US8377898B2
(en)
*
|
2006-10-12 |
2013-02-19 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
WO2008070672A2
(en)
*
|
2006-12-04 |
2008-06-12 |
The Board Of Trustees Of The University Of Illinois |
Compositions and methods to treat cancer with cupredoxins and cpg rich dna
|
|
EP2173912A4
(en)
*
|
2007-08-01 |
2013-03-20 |
Idera Pharmaceuticals Inc |
NEW SYNTHETIC AGONISTS OF TLR9
|
|
CA2696460A1
(en)
*
|
2007-08-13 |
2009-02-19 |
Pfizer Inc. |
Combination motif immune stimulatory oligonucleotides with improved activity
|
|
DK2207787T3
(en)
*
|
2007-11-06 |
2015-02-09 |
Adiutide Pharmaceuticals Gmbh |
Immunostimulatory oligoribonukleotidanaloger containing modified oligofosfatenheder
|
|
JP2012508013A
(ja)
*
|
2008-11-04 |
2012-04-05 |
イデラ ファーマシューティカルズ インコーポレイテッド |
アンチセンスオリゴヌクレオチドによるToll様受容体5発現の調節
|