FR2783170B1 - Emulsion immunostimulante - Google Patents

Emulsion immunostimulante

Info

Publication number
FR2783170B1
FR2783170B1 FR9811520A FR9811520A FR2783170B1 FR 2783170 B1 FR2783170 B1 FR 2783170B1 FR 9811520 A FR9811520 A FR 9811520A FR 9811520 A FR9811520 A FR 9811520A FR 2783170 B1 FR2783170 B1 FR 2783170B1
Authority
FR
France
Prior art keywords
immunostimulating
emulsion
immunostimulating emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9811520A
Other languages
English (en)
Other versions
FR2783170A1 (fr
Inventor
Jean Haensler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Pasteur Merieux Serum et Vaccines SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9811520A priority Critical patent/FR2783170B1/fr
Application filed by Pasteur Merieux Serum et Vaccines SA filed Critical Pasteur Merieux Serum et Vaccines SA
Priority to AU56278/99A priority patent/AU749282B2/en
Priority to NZ510419A priority patent/NZ510419A/xx
Priority to PCT/FR1999/002177 priority patent/WO2000015256A2/fr
Priority to EP99942961A priority patent/EP1121148A2/fr
Priority to US09/786,532 priority patent/US6610308B1/en
Priority to CA002342313A priority patent/CA2342313A1/fr
Publication of FR2783170A1 publication Critical patent/FR2783170A1/fr
Application granted granted Critical
Publication of FR2783170B1 publication Critical patent/FR2783170B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9811520A 1998-09-11 1998-09-11 Emulsion immunostimulante Expired - Fee Related FR2783170B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR9811520A FR2783170B1 (fr) 1998-09-11 1998-09-11 Emulsion immunostimulante
NZ510419A NZ510419A (en) 1998-09-11 1999-09-13 A vaccine adjuvant that is an oil-in-water immunoslimulant emulsion
PCT/FR1999/002177 WO2000015256A2 (fr) 1998-09-11 1999-09-13 Emulsion immunostimulante
EP99942961A EP1121148A2 (fr) 1998-09-11 1999-09-13 Emulsion immunostimulante
AU56278/99A AU749282B2 (en) 1998-09-11 1999-09-13 Immunostimulant emulsion
US09/786,532 US6610308B1 (en) 1998-09-11 1999-09-13 Immunostimulant emulsion
CA002342313A CA2342313A1 (fr) 1998-09-11 1999-09-13 Emulsion immunostimulante

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9811520A FR2783170B1 (fr) 1998-09-11 1998-09-11 Emulsion immunostimulante

Publications (2)

Publication Number Publication Date
FR2783170A1 FR2783170A1 (fr) 2000-03-17
FR2783170B1 true FR2783170B1 (fr) 2004-07-16

Family

ID=9530468

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9811520A Expired - Fee Related FR2783170B1 (fr) 1998-09-11 1998-09-11 Emulsion immunostimulante

Country Status (7)

Country Link
US (1) US6610308B1 (fr)
EP (1) EP1121148A2 (fr)
AU (1) AU749282B2 (fr)
CA (1) CA2342313A1 (fr)
FR (1) FR2783170B1 (fr)
NZ (1) NZ510419A (fr)
WO (1) WO2000015256A2 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US7935675B1 (en) 1994-07-15 2011-05-03 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6239116B1 (en) * 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US20030026782A1 (en) * 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
EP1733735B1 (fr) 1998-05-22 2017-03-22 Ottawa Hospital Research Institute Procédés et produits pour induire une immunité mucosale
US20030022854A1 (en) 1998-06-25 2003-01-30 Dow Steven W. Vaccines using nucleic acid-lipid complexes
EP2204186B1 (fr) 1999-02-17 2016-04-06 CSL Limited Complexes immunogènes et méthodes y relatives
WO2001037869A1 (fr) * 1999-11-19 2001-05-31 Csl Limited Compositions vaccinales
US7585847B2 (en) * 2000-02-03 2009-09-08 Coley Pharmaceutical Group, Inc. Immunostimulatory nucleic acids for the treatment of asthma and allergy
FR2814958B1 (fr) * 2000-10-06 2003-03-07 Aventis Pasteur Composition vaccinale
SG177000A1 (en) 2001-08-17 2012-01-30 Coley Pharm Gmbh Combination motif immune stimulatory oligonucleotides with improved activity
EP1434602B1 (fr) * 2001-10-06 2014-12-17 Merial Limited CpG plus huile en eau émulsions adjuvants pour herpèsvirus bovin de type 1 glycoprotéine D tronquéeÜ
US20040053880A1 (en) 2002-07-03 2004-03-18 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7576066B2 (en) 2002-07-03 2009-08-18 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7569553B2 (en) 2002-07-03 2009-08-04 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7807803B2 (en) 2002-07-03 2010-10-05 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7605138B2 (en) 2002-07-03 2009-10-20 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
ZA200503511B (en) 2002-10-29 2006-10-25 Coley Pharmaceutical Group Ltd Use of CPG oligonucleotides in the treatment of hepatitis C virus infection
US7956043B2 (en) 2002-12-11 2011-06-07 Coley Pharmaceutical Group, Inc. 5′ CpG nucleic acids and methods of use
AU2004275876B2 (en) 2003-09-25 2011-03-31 Coley Pharmaceutical Gmbh Nucleic acid-lipophilic conjugates
CA2567789A1 (fr) * 2004-06-08 2006-08-03 Coley Pharmaceutical Gmbh Oligonucleotide abasique utilise en tant que plate-forme support pour un antigene ainsi qu'un agoniste et un antagoniste immunostimulatoire
MX2009003398A (es) 2006-09-27 2009-08-12 Coley Pharm Gmbh Analogos de oligonucleotidos cpg que contienen analogos t hidrofobos con actividad inmunoestimuladora mejorada.
AU2011259718B2 (en) * 2010-05-28 2016-03-03 Zoetis Belgium S.A. Vaccines comprising cholesterol and CpG as sole adjuvant - carrier molecules
US10894963B2 (en) 2013-07-25 2021-01-19 Exicure, Inc. Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
CN106535876B (zh) 2014-06-04 2020-09-11 埃克西奎雷股份有限公司 免疫调节剂通过脂质体球形核酸的多价递送以用于预防或治疗应用
JP2017537619A (ja) 2014-11-21 2017-12-21 ノースウェスタン ユニバーシティ 球状核酸ナノ粒子複合体の配列特異的細胞内取込
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids
US11696954B2 (en) 2017-04-28 2023-07-11 Exicure Operating Company Synthesis of spherical nucleic acids using lipophilic moieties

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2194761C (fr) * 1994-07-15 2006-12-19 Arthur M. Krieg Oligonucleotides immunomodulateurs
US5866699A (en) * 1994-07-18 1999-02-02 Hybridon, Inc. Oligonucleotides with anti-MDR-1 gene activity
US5908777A (en) * 1995-06-23 1999-06-01 University Of Pittsburgh Lipidic vector for nucleic acid delivery
ATE441432T1 (de) * 1997-03-10 2009-09-15 Ottawa Hospital Res Inst Verwendung von nicht-methyliertem cpg dinukleotid in kombination mit aluminium als adjuvantien

Also Published As

Publication number Publication date
CA2342313A1 (fr) 2000-03-23
FR2783170A1 (fr) 2000-03-17
EP1121148A2 (fr) 2001-08-08
AU5627899A (en) 2000-04-03
AU749282B2 (en) 2002-06-20
WO2000015256A2 (fr) 2000-03-23
NZ510419A (en) 2003-01-31
WO2000015256A3 (fr) 2000-07-13
US6610308B1 (en) 2003-08-26

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Legal Events

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CD Change of name or company name
CD Change of name or company name
ST Notification of lapse

Effective date: 20070531