|
US20080281041A1
(en)
|
1999-06-07 |
2008-11-13 |
Rozema David B |
Reversibly Masked Polymers
|
|
USRE43612E1
(en)
|
2000-10-10 |
2012-08-28 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
|
US6998115B2
(en)
*
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
|
US7223851B2
(en)
*
|
2003-02-06 |
2007-05-29 |
General Dynamics Advanced Information Systems, Inc. |
Nucleic acid-binding polymers
|
|
US7309757B2
(en)
|
2003-06-20 |
2007-12-18 |
Agency For Science, Technology And Research |
Polymers for the delivery of bioactive agents and methods of their preparation
|
|
US7883720B2
(en)
|
2003-07-09 |
2011-02-08 |
Wisconsin Alumni Research Foundation |
Charge-dynamic polymers and delivery of anionic compounds
|
|
US7943179B2
(en)
*
|
2003-09-23 |
2011-05-17 |
Massachusetts Institute Of Technology |
pH triggerable polymeric particles
|
|
US20050123596A1
(en)
*
|
2003-09-23 |
2005-06-09 |
Kohane Daniel S. |
pH-triggered microparticles
|
|
EP1730286A4
(en)
*
|
2004-03-04 |
2007-09-05 |
Massachusetts Inst Technology |
THERAPEUTIC ANTICIPLE DNA
|
|
WO2005110438A2
(en)
*
|
2004-04-15 |
2005-11-24 |
Massachusetts Institute Of Technology |
Methods and products related to the intracellular delivery of polysaccharides
|
|
KR20050102295A
(ko)
*
|
2004-04-21 |
2005-10-26 |
학교법인 포항공과대학교 |
리포좀 및 그 제조방법
|
|
US7358223B2
(en)
*
|
2004-10-04 |
2008-04-15 |
Nitto Denko Corporation |
Biodegradable cationic polymers
|
|
US20120269886A1
(en)
|
2004-12-22 |
2012-10-25 |
Nitto Denko Corporation |
Therapeutic agent for pulmonary fibrosis
|
|
HUE056941T2
(hu)
|
2004-12-22 |
2022-04-28 |
Nitto Denko Corp |
Gyógyszerhordozó és gyógyszerhordozó kit fibrózis gátlására
|
|
KR100732013B1
(ko)
*
|
2005-03-18 |
2007-06-25 |
성균관대학교산학협력단 |
pH 민감성 블록 공중합체 및 이를 이용한 고분자 마이셀
|
|
JP5541861B2
(ja)
*
|
2005-04-29 |
2014-07-09 |
エージェンシー フォー サイエンス, テクノロジー アンド リサーチ |
超分岐ポリマーおよびそれらの適用
|
|
US20060257355A1
(en)
*
|
2005-05-10 |
2006-11-16 |
Abiomed, Inc. |
Impregnated polymer compositions and devices using them
|
|
CN101346393B
(zh)
|
2005-11-02 |
2015-07-22 |
普洛体维生物治疗公司 |
修饰的siRNA分子及其应用
|
|
WO2007067733A2
(en)
*
|
2005-12-09 |
2007-06-14 |
Massachusetts Institute Of Technology |
Compositions and methods to monitor rna delivery to cells
|
|
US9572886B2
(en)
|
2005-12-22 |
2017-02-21 |
Nitto Denko Corporation |
Agent for treating myelofibrosis
|
|
US7700541B2
(en)
*
|
2006-04-06 |
2010-04-20 |
Nitto Denko Corporation |
Biodegradable cationic polymers
|
|
US8808681B2
(en)
*
|
2006-06-05 |
2014-08-19 |
Massachusetts Institute Of Technology |
Crosslinked, degradable polymers and uses thereof
|
|
CN100428964C
(zh)
*
|
2006-06-29 |
2008-10-29 |
武汉理工大学 |
RGD多肽接枝聚(羟基乙酸-L-赖氨酸-L-乳酸)/β-磷酸三钙复合材料及其制备方法
|
|
EP2046266A4
(en)
*
|
2006-07-21 |
2009-11-04 |
Massachusetts Inst Technology |
ENDMODICIFIED POLY (BETA AMINO ESTER) AND ITS USE
|
|
CN101500548A
(zh)
*
|
2006-08-18 |
2009-08-05 |
弗·哈夫曼-拉罗切有限公司 |
用于体内递送多核苷酸的多缀合物
|
|
WO2008073856A2
(en)
*
|
2006-12-08 |
2008-06-19 |
Massachusetts Institute Of Technology |
Delivery of nanoparticles and/or agents to cells
|
|
KR100825519B1
(ko)
*
|
2007-01-05 |
2008-04-25 |
주식회사 바이오폴리메드 |
키토산 기재 고분자 접합체 및 그 제조방법
|
|
US20100196492A1
(en)
*
|
2007-03-08 |
2010-08-05 |
Green Jordan J |
Electrostatic coating of particles for drug delivery
|
|
TWI407971B
(zh)
|
2007-03-30 |
2013-09-11 |
日東電工股份有限公司 |
Cancer cells and tumor-related fibroblasts
|
|
WO2008157372A2
(en)
|
2007-06-14 |
2008-12-24 |
Massachusetts Institute Of Technology |
Self assembled films for protein and drug delivery applications
|
|
CN101970012A
(zh)
|
2007-09-14 |
2011-02-09 |
日东电工株式会社 |
药物载体
|
|
PL2214646T3
(pl)
|
2007-10-05 |
2021-12-20 |
Wayne State University |
Dendrymery do przedłużonego uwalniania związków
|
|
WO2009049100A2
(en)
|
2007-10-09 |
2009-04-16 |
Wisconsin Alumni Research Foundation |
Ultrathin multilayered films for controlled release of anionic reagents
|
|
CN101952434B
(zh)
*
|
2007-12-13 |
2016-11-16 |
聚加转染公司 |
使用合成的聚合物递送对基因沉默有活性的核酸的工具
|
|
ES2535419T3
(es)
|
2007-12-27 |
2015-05-11 |
Protiva Biotherapeutics Inc. |
Silenciamiento de expresión de quinasa tipo polo usando ARN interferente
|
|
US20110059172A1
(en)
*
|
2008-01-29 |
2011-03-10 |
Arthur Tzianabos |
Therapeutic compositions
|
|
EP2244698A1
(en)
*
|
2008-02-25 |
2010-11-03 |
The University Of North Carolina At Charlotte Office Of Technology Transfer |
Biodegradable therapeutic nanoparticles containing an antimicrobial agent
|
|
EP2281041B1
(en)
|
2008-04-15 |
2014-07-02 |
Protiva Biotherapeutics Inc. |
Silencing of csn5 gene expression using interfering rna
|
|
US8324333B2
(en)
|
2008-06-05 |
2012-12-04 |
Wisconsin Alumni Research Foundation |
Anionic charge-dynamic polymers for release of cationic agents
|
|
BRPI0910198A2
(pt)
|
2008-06-30 |
2016-01-12 |
Silenseed Ltd |
composição para administração a partir de um sítio local de um agente baseado em nucleotídeos e método para tratar um sujeito sofrendo de uma doença requerendo tratamento local com um agente baseado em nucleotídeo.
|
|
WO2010021973A2
(en)
|
2008-08-17 |
2010-02-25 |
Massachusetts Institute Of Technology |
Controlled delivery of bioactive agents from decomposable films
|
|
EP3269395A1
(en)
|
2008-11-07 |
2018-01-17 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
CN111808084A
(zh)
|
2008-11-10 |
2020-10-23 |
阿布特斯生物制药公司 |
用于递送治疗剂的新型脂质和组合物
|
|
US8163861B2
(en)
*
|
2009-01-15 |
2012-04-24 |
Living Proof, Inc. |
Beta-amino ester compounds and uses thereof
|
|
US8921288B2
(en)
*
|
2009-02-18 |
2014-12-30 |
The Lubrizol Corporation |
Composition containing ester compounds and a method of lubricating an internal combustion engine
|
|
EP2408458A1
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
JP2012520684A
(ja)
|
2009-03-19 |
2012-09-10 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたBTBandCNCHomology1(塩基性ロイシンジッパー転写因子1)(Bach1)遺伝子発現のRNA干渉媒介性阻害
|
|
EP2408916A2
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
US20120029054A1
(en)
|
2009-03-19 |
2012-02-02 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of GATA Binding Protein 3 (GATA3) Gene Expression Using Short Intefering Nucleic Acid (siNA)
|
|
WO2010111497A2
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE INTERCELLULAR ADHESION MOLECULE 1 (ICAM-1)GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
EP2411018A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE NERVE GROWTH FACTOR BETA CHAIN (NGFß) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)
|
|
JP2012521760A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたアポトーシスシグナル調節キナーゼ1(ASK1)遺伝子発現のRNA干渉媒介性阻害
|
|
EP2411520A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
WO2010111471A2
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
WO2010132879A2
(en)
|
2009-05-15 |
2010-11-18 |
The Johns Hopkins University |
Multicomponent degradable cationic polymers
|
|
US9717694B2
(en)
|
2009-05-15 |
2017-08-01 |
The Johns Hopkins University |
Peptide/particle delivery systems
|
|
EP3318248B1
(en)
|
2009-12-01 |
2019-04-10 |
Translate Bio, Inc. |
Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
|
|
WO2011081659A1
(en)
|
2009-12-15 |
2011-07-07 |
Massachusetts Institute Of Technology |
Degradable polymer nanostructure materials
|
|
WO2011078457A2
(ko)
|
2009-12-22 |
2011-06-30 |
성균관대학교산학협력단 |
다이온성 복합체 마이셀을 형성하는 피에이치 민감성 블록공중합체 및 이를 이용한 약물 또는 단백질 전달체
|
|
KR101291642B1
(ko)
*
|
2010-03-03 |
2013-08-01 |
성균관대학교산학협력단 |
폴리(아미도 아민) 올리고머 하이드로젤 조성물 및 이를 이용한 약물전달체
|
|
WO2011111067A2
(en)
|
2010-03-09 |
2011-09-15 |
Council Of Scientific & Industrial Research |
A biodegradable polymeric hydrogel composition
|
|
EP2553019A1
(en)
|
2010-03-26 |
2013-02-06 |
Mersana Therapeutics, Inc. |
Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof
|
|
CA2802994A1
(en)
|
2010-06-17 |
2011-12-22 |
The United States Of America As Represented By The Secretary, National I Nstitutes Of Health |
Compositions and methods for treating inflammatory conditions
|
|
EP3330377A1
(en)
|
2010-08-02 |
2018-06-06 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina)
|
|
GB2482709A
(en)
*
|
2010-08-11 |
2012-02-15 |
Envirogene Ltd |
Tracer
|
|
US9243246B2
(en)
|
2010-08-24 |
2016-01-26 |
Sirna Therapeutics, Inc. |
Single-stranded RNAi agents containing an internal, non-nucleic acid spacer
|
|
US9193827B2
(en)
|
2010-08-26 |
2015-11-24 |
Massachusetts Institute Of Technology |
Poly(beta-amino alcohols), their preparation, and uses thereof
|
|
WO2012027467A1
(en)
|
2010-08-26 |
2012-03-01 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
WO2012058210A1
(en)
|
2010-10-29 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA)
|
|
US8642087B1
(en)
|
2010-11-05 |
2014-02-04 |
University Of Kentucky Research Foundation |
Compounds and methods for reducing oxidative stress
|
|
EP2691443B1
(en)
|
2011-03-28 |
2021-02-17 |
Massachusetts Institute of Technology |
Conjugated lipomers and uses thereof
|
|
US9012424B2
(en)
|
2011-05-27 |
2015-04-21 |
20Med Therapeutics B.V. |
Nanogels
|
|
RU2013154295A
(ru)
|
2011-06-08 |
2015-07-20 |
Шир Хьюман Дженетик Терапис, Инк. |
КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК
|
|
US20140234373A1
(en)
|
2011-09-16 |
2014-08-21 |
Georfia Regents University |
Methods of Promoting Immune Tolerance
|
|
PE20181541A1
(es)
|
2011-10-27 |
2018-09-26 |
Massachusetts Inst Technology |
Derivados de aminoacidos funcionalizados en la terminal n capaces de formar microesferas encapsuladoras de farmaco
|
|
AU2012340086A1
(en)
|
2011-11-17 |
2014-05-29 |
The Regents Of The University Of California |
Therapeutic RNA switches compositions and methods of use
|
|
IN2014DN05912A
(https=)
|
2011-12-16 |
2015-06-05 |
Massachusetts Inst Technology |
|
|
US9035039B2
(en)
|
2011-12-22 |
2015-05-19 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing SMAD4
|
|
EP2817328A1
(en)
|
2012-02-21 |
2014-12-31 |
Institut National de la Santé et de la Recherche Médicale |
Tam receptors as virus entry cofactors
|
|
US20160017035A1
(en)
|
2012-02-21 |
2016-01-21 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Tim receptors as virus entry cofactors
|
|
EP2841056A4
(en)
|
2012-04-23 |
2015-09-16 |
Massachusetts Inst Technology |
STABLE LAYER COATED PARTICLES
|
|
WO2013185067A1
(en)
|
2012-06-08 |
2013-12-12 |
Shire Human Genetic Therapies, Inc. |
Nuclease resistant polynucleotides and uses thereof
|
|
CA2820236C
(en)
|
2012-06-15 |
2022-07-19 |
The Royal Institution For The Advancement Of Learning/Mcgill University |
Non-viral nanoparticle-based delivery system
|
|
WO2014016152A1
(en)
|
2012-07-27 |
2014-01-30 |
Institut National De La Sante Et De La Recherche Medicale |
Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
|
|
WO2014028487A1
(en)
|
2012-08-13 |
2014-02-20 |
Massachusetts Institute Of Technology |
Amine-containing lipidoids and uses thereof
|
|
US9687569B2
(en)
*
|
2012-08-16 |
2017-06-27 |
University Of Washington Through Its Center For Commercialization |
Theranostic nanoparticle and methods for making and using the nanoparticle
|
|
KR101445265B1
(ko)
*
|
2012-09-18 |
2014-09-30 |
포항공과대학교 산학협력단 |
히알루론산-핵산 접합체 및 이를 포함하는 핵산 전달용 조성물
|
|
WO2014134029A1
(en)
|
2013-02-26 |
2014-09-04 |
Massachusetts Institute Of Technology |
Nucleic acid particles, methods and use thereof
|
|
GB201304245D0
(en)
*
|
2013-03-08 |
2013-04-24 |
Inst Quimic De Sarria |
Chemical compounds
|
|
JP6586075B2
(ja)
|
2013-03-14 |
2019-10-02 |
トランスレイト バイオ, インコーポレイテッド |
メッセンジャーrnaの精製方法
|
|
RS57739B1
(sr)
|
2013-03-14 |
2018-12-31 |
Translate Bio Inc |
Kompozicije cftr irnk i postupci i upotrebe u vezi sa njima
|
|
US9463244B2
(en)
|
2013-03-15 |
2016-10-11 |
Massachusetts Institute Of Technology |
Compositions and methods for nucleic acid delivery
|
|
WO2014179562A1
(en)
|
2013-05-01 |
2014-11-06 |
Massachusetts Institute Of Technology |
1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
|
|
ES3032935T3
(en)
|
2013-10-22 |
2025-07-29 |
Translate Bio Inc |
Lipid formulations for delivery of messenger rna
|
|
CN106413811A
(zh)
|
2013-10-22 |
2017-02-15 |
夏尔人类遗传性治疗公司 |
精氨基琥珀酸合成酶缺乏症的mrna疗法
|
|
JP6506749B2
(ja)
|
2013-10-22 |
2019-04-24 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
フェニルケトン尿症のためのmRNA療法
|
|
US20160251680A1
(en)
*
|
2013-11-05 |
2016-09-01 |
Clontech Laboratories, Inc. |
Dry transfection compositions and methods for making and using the same
|
|
US9850269B2
(en)
|
2014-04-25 |
2017-12-26 |
Translate Bio, Inc. |
Methods for purification of messenger RNA
|
|
CA2946422C
(en)
|
2014-04-30 |
2019-03-05 |
The Johns Hopkins University |
Dendrimer compositions and their use in treatment of diseases of the eye
|
|
JP6557722B2
(ja)
|
2014-05-30 |
2019-08-07 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
核酸の送達のための生分解性脂質
|
|
EP3155116A4
(en)
|
2014-06-10 |
2017-12-27 |
Massachusetts Institute Of Technology |
Method for gene editing
|
|
KR102559979B1
(ko)
|
2014-06-24 |
2023-07-25 |
샤이어 휴먼 지네틱 테라피즈 인크. |
핵산의 전달용 입체화학적으로 풍부한 조성물
|
|
US9840479B2
(en)
|
2014-07-02 |
2017-12-12 |
Massachusetts Institute Of Technology |
Polyamine-fatty acid derived lipidoids and uses thereof
|
|
US10736966B2
(en)
|
2014-08-12 |
2020-08-11 |
Massachusetts Institute Of Technology |
Brush-poly (glycoamidoamine)-lipids and uses thereof
|
|
JP6342575B2
(ja)
|
2014-08-13 |
2018-06-13 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
脳腫瘍への選択的デンドリマー送達
|
|
EP2995318B1
(en)
*
|
2014-09-09 |
2022-12-07 |
Istanbul Universitesi Rektorlugu |
Synthesis of nanoparticular gene carrier systems based on poly(beta-aminoesters)
|
|
EP3201338B1
(en)
|
2014-10-02 |
2021-11-03 |
Arbutus Biopharma Corporation |
Compositions and methods for silencing hepatitis b virus gene expression
|
|
WO2016094342A1
(en)
|
2014-12-08 |
2016-06-16 |
The Board Of Regents Of The University Of Texas System |
Lipocationic polymers and uses thereof
|
|
WO2016197132A1
(en)
|
2015-06-04 |
2016-12-08 |
Protiva Biotherapeutics Inc. |
Treating hepatitis b virus infection using crispr
|
|
WO2016205691A1
(en)
|
2015-06-19 |
2016-12-22 |
Massachusetts Institute Of Technology |
Alkenyl substituted 2,5-piperazinediones and their use in compositions for delivering an agent to a subject or cell
|
|
WO2017019891A2
(en)
|
2015-07-29 |
2017-02-02 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing hepatitis b virus gene expression
|
|
CN105131182B
(zh)
*
|
2015-09-06 |
2017-07-21 |
山东大学 |
普朗尼克‑聚(β‑氨基酯)聚合物及其合成和应用方法
|
|
GB201519375D0
(en)
*
|
2015-11-03 |
2015-12-16 |
Univ Cardiff |
Photodynamic therapy complex
|
|
US10413616B2
(en)
|
2015-12-23 |
2019-09-17 |
Viking Scientific, Inc. |
Hydrogel prodrug for treatment
|
|
US10188749B2
(en)
*
|
2016-04-14 |
2019-01-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
EP4711465A2
(en)
*
|
2016-04-14 |
2026-03-18 |
Fred Hutchinson Cancer Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
EP3500294A4
(en)
|
2016-08-22 |
2020-07-29 |
Arbutus Biopharma Corporation |
ANTI-PD-1 ANTIBODIES, OR THEIR FRAGMENTS, FOR THE TREATMENT OF HEPATITIS B
|
|
CN110121336A
(zh)
|
2017-01-05 |
2019-08-13 |
弗莱德哈钦森癌症研究中心 |
改善疫苗功效的系统和方法
|
|
EA201991747A1
(ru)
|
2017-02-27 |
2020-06-04 |
Транслейт Био, Инк. |
НОВАЯ КОДОН-ОПТИМИЗИРОВАННАЯ мРНК CFTR
|
|
MX2019013752A
(es)
|
2017-05-16 |
2020-07-20 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr optimizado en codones.
|
|
WO2019075056A1
(en)
*
|
2017-10-10 |
2019-04-18 |
The Johns Hopkins University |
BIODEGRADABLE BIOMIMETIC PARTICLES
|
|
EP3700965A1
(en)
|
2017-10-27 |
2020-09-02 |
Massachusetts Institute of Technology |
Poly (beta-amino esters) and uses thereof
|
|
WO2019089567A1
(en)
|
2017-10-30 |
2019-05-09 |
Massachusetts Institute Of Technology |
Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
|
|
EP3713603A1
(en)
|
2017-11-23 |
2020-09-30 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
New method for treating dengue virus infection
|
|
CN109954144B
(zh)
*
|
2017-12-14 |
2022-07-08 |
复旦大学 |
基于改性聚β-氨基酯材料的双级pH响应纳米粒及其制备方法
|
|
KR20250099256A
(ko)
|
2018-01-18 |
2025-07-01 |
프레드 허친슨 캔서 센터 |
세포 활성화 상태를 조절함으로써 생체내 면역 세포의 염증 상태의 변경
|
|
KR102950141B1
(ko)
|
2018-08-24 |
2026-04-07 |
트랜슬레이트 바이오 인코포레이티드 |
전령 rna의 정제 방법
|
|
JP7450945B2
(ja)
|
2018-08-30 |
2024-03-18 |
テナヤ セラピューティクス, インコーポレイテッド |
ミオカルディンおよびascl1を用いた心細胞リプログラミング
|
|
EP3870629A1
(en)
|
2018-10-26 |
2021-09-01 |
Massachusetts Institute of Technology |
Polymer-lipids and compositions
|
|
WO2020106946A1
(en)
|
2018-11-21 |
2020-05-28 |
Translate Bio, Inc. |
TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF NEBULIZED mRNA ENCODING CFTR
|
|
EP3714913A1
(en)
*
|
2019-03-29 |
2020-09-30 |
Picosun Oy |
Color coding
|
|
WO2020230084A1
(en)
*
|
2019-05-14 |
2020-11-19 |
Universidade De Coimbra |
A light-triggerable nanoparticle library of formulations for the controlled release of rnas
|
|
JP2022532256A
(ja)
|
2019-05-16 |
2022-07-13 |
ジェム イノヴ |
生分解性マイクロカプセルの調製方法及びこの方法で得たマイクロカプセル
|
|
WO2021002984A1
(en)
|
2019-05-30 |
2021-01-07 |
Massachusetts Institute Of Technology |
Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
|
|
EP3997226A1
(en)
|
2019-07-11 |
2022-05-18 |
Tenaya Therapeutics, Inc. |
Cardiac cell reprogramming with micrornas and other factors
|
|
EP4031662A1
(en)
|
2019-09-20 |
2022-07-27 |
Translate Bio, Inc. |
Mrna encoding engineered cftr
|
|
JP7759322B2
(ja)
|
2019-12-04 |
2025-10-23 |
アシュバッタ セラピューティクス, インコーポレイテッド |
眼に薬物送達するためのデンドリマー組成物および方法
|
|
CN111568856B
(zh)
*
|
2020-06-24 |
2021-07-06 |
珠海舒桐医疗科技有限公司 |
一种阴道凝胶制剂及其制备方法
|
|
US11945946B2
(en)
|
2020-09-14 |
2024-04-02 |
Encapsys, Llc |
Polyurea and poly(beta-amino ester) capsules with enhanced degradability
|
|
CN115403828A
(zh)
*
|
2020-11-11 |
2022-11-29 |
绍兴瑞康生物科技有限公司 |
空间位阻可调型弱碱光稳定剂及其制备方法和应用
|
|
FR3116211A1
(fr)
*
|
2020-11-17 |
2022-05-20 |
Gem'innov |
Procede de preparation de microcapsules biodegradables et utilisation des microcapsules ainsi obtenues
|
|
FR3116212B1
(fr)
|
2020-11-18 |
2022-12-30 |
Gem Innov |
Procede de preparation de microcapsules biodegradables et microcapsules ainsi obtenues
|
|
US20220153901A1
(en)
*
|
2020-11-19 |
2022-05-19 |
Encapsys,LLC |
Poly Acrylate and Poly(Beta-Amino Ester) Capsules with Enhanced Degradability
|
|
EP4000725A1
(en)
|
2020-11-19 |
2022-05-25 |
The Procter & Gamble Company |
Consumer product comprising poly acrylate and poly(beta-amino ester) delivery capsules with enhanced degradability
|
|
CN112851934B
(zh)
*
|
2020-12-29 |
2022-05-10 |
浙江大学杭州国际科创中心 |
一种含N-氧化三级胺基团的聚(β-氨基酯)及其制备方法和应用
|
|
US12433847B2
(en)
|
2021-03-09 |
2025-10-07 |
Massachusetts Institute Of Technology |
Branched poly(-amino esters) for the delivery of nucleic acids
|
|
WO2023059806A1
(en)
|
2021-10-06 |
2023-04-13 |
Massachusetts Institute Of Technology |
Lipid nanoparticles for drug delivery to microglia in the brain
|
|
CN113929904B
(zh)
*
|
2021-10-14 |
2022-10-25 |
西安交通大学 |
一类功能性单链环状聚(β-氨基酯)及其制备方法和基因递送药物应用
|
|
CA3234809A1
(en)
|
2021-10-20 |
2023-04-27 |
Steven Goldman |
Isolated glial progenitor cells for use in the competition treatment of age-related white matter loss
|
|
EP4183884A1
(en)
*
|
2021-11-19 |
2023-05-24 |
Branca Bunus Limited |
A method of preparing a fraction of a starting polymer vector for gene therapy
|
|
EP4441120A1
(en)
*
|
2021-11-30 |
2024-10-09 |
Massachusetts Institute of Technology |
Poly(?-amino ester) microparticles for micronutrient fortification
|
|
CN120129519A
(zh)
*
|
2022-11-01 |
2025-06-10 |
浦项工科大学校产学协力团 |
基于具有电离部分的聚合物的核酸分子递送载体
|
|
CN116396476B
(zh)
*
|
2023-04-18 |
2026-02-24 |
西安交通大学 |
一类末端为两性离子功能化的高度支化聚(β-氨基酯)及其制备方法和应用
|
|
WO2025090427A1
(en)
|
2023-10-23 |
2025-05-01 |
University Of Rochester |
Glial-targeted relief of hyperexcitability in neurodegenerative diseases
|
|
CN118755084B
(zh)
*
|
2024-06-13 |
2025-09-16 |
浙江工业大学 |
用于mRNA递送的聚合物、利用该聚合物的脂质/聚合物杂化纳米粒及其制备方法和应用
|