JP2007504132A5 - - Google Patents

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Publication number
JP2007504132A5
JP2007504132A5 JP2006524705A JP2006524705A JP2007504132A5 JP 2007504132 A5 JP2007504132 A5 JP 2007504132A5 JP 2006524705 A JP2006524705 A JP 2006524705A JP 2006524705 A JP2006524705 A JP 2006524705A JP 2007504132 A5 JP2007504132 A5 JP 2007504132A5
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JP
Japan
Prior art keywords
compound
daltons
molecular weight
group
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2006524705A
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English (en)
Japanese (ja)
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JP4848277B2 (ja
JP2007504132A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/026422 external-priority patent/WO2005023834A2/en
Publication of JP2007504132A publication Critical patent/JP2007504132A/ja
Publication of JP2007504132A5 publication Critical patent/JP2007504132A5/ja
Application granted granted Critical
Publication of JP4848277B2 publication Critical patent/JP4848277B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2006524705A 2003-08-28 2004-08-13 受容体に結合するペプチドおよび化合物 Expired - Lifetime JP4848277B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49874003P 2003-08-28 2003-08-28
US60/498,740 2003-08-28
PCT/US2004/026422 WO2005023834A2 (en) 2003-08-28 2004-08-13 Peptides and compounds that bind to thrombopoietin receptors

Publications (3)

Publication Number Publication Date
JP2007504132A JP2007504132A (ja) 2007-03-01
JP2007504132A5 true JP2007504132A5 (enExample) 2007-09-20
JP4848277B2 JP4848277B2 (ja) 2011-12-28

Family

ID=34272720

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006524705A Expired - Lifetime JP4848277B2 (ja) 2003-08-28 2004-08-13 受容体に結合するペプチドおよび化合物

Country Status (32)

Country Link
US (1) US7576056B2 (enExample)
EP (1) EP1675606B1 (enExample)
JP (1) JP4848277B2 (enExample)
KR (2) KR101183875B1 (enExample)
CN (2) CN102241742B (enExample)
AR (1) AR045530A1 (enExample)
AU (1) AU2004270656B2 (enExample)
BR (1) BRPI0414008B8 (enExample)
CA (1) CA2537421C (enExample)
CY (1) CY1118965T1 (enExample)
DK (1) DK1675606T3 (enExample)
EA (1) EA009286B1 (enExample)
EC (1) ECSP066396A (enExample)
ES (1) ES2626107T3 (enExample)
HR (1) HRP20170810T1 (enExample)
HU (1) HUE032370T2 (enExample)
IL (1) IL173965A (enExample)
IS (1) IS8300A (enExample)
LT (1) LT1675606T (enExample)
ME (1) ME00313B (enExample)
MX (1) MXPA06002292A (enExample)
NO (1) NO344233B1 (enExample)
NZ (1) NZ545455A (enExample)
PL (1) PL1675606T3 (enExample)
PT (1) PT1675606T (enExample)
RS (2) RS56387B1 (enExample)
SG (1) SG131110A1 (enExample)
SI (1) SI1675606T1 (enExample)
TW (1) TWI348375B (enExample)
UA (1) UA82710C2 (enExample)
WO (1) WO2005023834A2 (enExample)
ZA (1) ZA200602495B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
ATE348163T1 (de) 1998-10-23 2007-01-15 Amgen Inc Thrombopoietin substitute
KR20050093759A (ko) * 2002-09-18 2005-09-23 오르토-맥네일 파마슈티칼, 인코퍼레이티드 혈소판 및 조혈 줄기세포의 생산을 증가시키는 방법
US20040149235A1 (en) * 2002-10-04 2004-08-05 Pogue Albert S. Apparatus and method for removal of waste from animal production facilities
US7723295B2 (en) * 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
EP1675606B1 (en) 2003-08-28 2017-04-05 Janssen Pharmaceuticals, Inc. Peptides and compounds that bind to thrombopoietin receptors
US7615533B2 (en) 2004-08-16 2009-11-10 Janssen Pharmaceutica N.V. TPO peptide compounds for treatment of anemia
EP1986677A2 (en) * 2006-01-25 2008-11-05 Amgen Inc. Thrombopoietic compounds
TWI458488B (zh) * 2006-02-14 2014-11-01 Janssen Pharmaceutica Nv Ｔｐｏ胜肽化合物及醫藥組成物於治療貧血之用途
AU2006338308B2 (en) * 2006-02-14 2012-11-01 Janssen Pharmaceutica N.V. Use of TPO peptide compounds and pharmaceutical compositions in the treatment of anemia
US7981425B2 (en) 2006-06-19 2011-07-19 Amgen Inc. Thrombopoietic compounds
AU2009256465B2 (en) * 2008-06-03 2015-05-14 Janssen Pharmaceutica Nv TPO mimetic peptide for preventing hematological disorder associated with cancer treatment
WO2012176885A1 (ja) 2011-06-23 2012-12-27 株式会社 島津製作所 分岐型両親媒性ブロックポリマー、それを用いた分子集合体及び薬剤搬送システム
JP7481252B2 (ja) * 2017-07-26 2024-05-10 ヤンセン ファーマシューティカ エヌ．ベー． 標的放射線治療誘発性血管完全性を保護する方法
EP3914281A1 (en) * 2019-01-25 2021-12-01 Janssen Pharmaceutica NV Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
AU2020211412A1 (en) 2019-01-25 2021-08-12 Janssen Pharmaceutica Nv Methods for mitigating liver injury and promoting liver hypertrophy, regeneration and cell engraftment in conjunction with radiation and/or radiomimetic treatments
CN113905754B (zh) 2019-01-25 2025-03-11 詹森药业有限公司 减轻起疱剂和腐蚀性气体毒性作用的方法
EP4408984A1 (en) 2021-10-01 2024-08-07 Janssen Pharmaceutica NV Methods of increasing progenitor cell production
WO2024095178A1 (en) 2022-11-01 2024-05-10 Janssen Pharmaceutica Nv Thrombopoietin mimetic for use in the treatment of acute liver failure

Family Cites Families (33)

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Publication number Priority date Publication date Assignee Title
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5326558A (en) * 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
IL96477A0 (en) 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
DK167813B1 (da) * 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US5571508A (en) 1989-12-18 1996-11-05 Amrad Corporation Limited Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor
IT1241395B (it) 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
US5141851A (en) * 1990-04-18 1992-08-25 Board Of Regents, The University Of Texas System Isolated farnesyl protein transferase enzyme
US5250732A (en) * 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
JPH07507806A (ja) 1992-06-11 1995-08-31 アルカーメス　コントロールド　セラピューティクス，インコーポレイテッド エリスロポエチン薬物送達システム
CA2150371C (en) * 1992-12-11 2002-09-17 Dov Borovsky Materials and methods for control of pests
AU8124694A (en) 1993-10-29 1995-05-22 Affymax Technologies N.V. In vitro peptide and antibody display libraries
SG47030A1 (en) 1994-01-03 1998-03-20 Genentech Inc Thrombopoietin
EP0668352A1 (en) 1994-02-14 1995-08-23 Kirin Brewery Company, Ltd. Protein having TPO activity
CZ221496A3 (en) 1994-02-14 1997-07-16 Zymogenetics Inc Haematopoetic protein, materials and processes for preparing thereof
WO1995021626A1 (en) 1994-02-14 1995-08-17 University Of Washington Methods for stimulating erythropoiesis using thrombopoietin
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
TW496870B (en) 1994-03-31 2002-08-01 Amgen Inc Compositions methods for stimulating megakaryocyte growth and differentiation
US5571686A (en) 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets
CA2180021A1 (en) * 1994-11-04 1996-05-17 Yoichi Kawashima Novel 1,3-dialkylurea derivatives having a hydroxyl group
US5641655A (en) 1994-11-30 1997-06-24 Zymogenetics, Inc. Methods for producing thrombopoietin polypeptides using a mammalian tissue plasminogen activator secretory peptide
AU4163196A (en) 1994-11-30 1996-06-19 Zymogenetics Inc. Low molecular weight thrombopoietin
ES2276401T3 (es) 1995-04-26 2007-06-16 Kyowa Hakko Kogyo Co., Ltd. Proteinas de fusion g-csf tpo.
US5869451A (en) 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
PT885242E (pt) * 1995-06-07 2008-06-18 Glaxo Group Ltd Péptidos e compostos que se ligam a um receptor de trombopoietina
US6060052A (en) * 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5932546A (en) * 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
DE60032783T2 (de) 1999-09-24 2007-12-06 Smithkline Beecham Corp. Thrombopoietinmimetika
CN1481389A (zh) * 2000-12-22 2004-03-10 ���ɶ��ؼ����� 含色氨酸残基的肽的合成方法
AU2002307062A1 (en) 2001-04-02 2002-10-15 Purdue Pharma L.P. Thrombopoietin (tpo) synthebody for stimulation of platelet production
KR20050093759A (ko) 2002-09-18 2005-09-23 오르토-맥네일 파마슈티칼, 인코퍼레이티드 혈소판 및 조혈 줄기세포의 생산을 증가시키는 방법
EP1675606B1 (en) 2003-08-28 2017-04-05 Janssen Pharmaceuticals, Inc. Peptides and compounds that bind to thrombopoietin receptors

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