JP2006519193A - ２型糖尿病およびアテローム性動脈硬化症の治療のためのｐｐａｒモジュレーターとしての３−メチル−２−（３−（２−フェニル−オキサゾール−４−イルメトキシ）−シクロヘキサンカルボニル−アミノ酪酸誘導体および関連化合物 - Google Patents
２型糖尿病およびアテローム性動脈硬化症の治療のためのｐｐａｒモジュレーターとしての３−メチル−２−（３−（２−フェニル−オキサゾール−４−イルメトキシ）−シクロヘキサンカルボニル−アミノ酪酸誘導体および関連化合物 Download PDFInfo
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- JP2006519193A JP2006519193A JP2006501885A JP2006501885A JP2006519193A JP 2006519193 A JP2006519193 A JP 2006519193A JP 2006501885 A JP2006501885 A JP 2006501885A JP 2006501885 A JP2006501885 A JP 2006501885A JP 2006519193 A JP2006519193 A JP 2006519193A
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- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10308355A DE10308355A1 (de) | 2003-02-27 | 2003-02-27 | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
| PCT/EP2004/001578 WO2004076426A1 (de) | 2003-02-27 | 2004-02-19 | 3-methyl-2- (3- (2-phenyl-oxazol-4-ylmethoxy)-cyclohexancarbonyl-amino)-buttersäurederivate und verwandte verbindungen als ppar modulatoren zur behandlung von typ 2 diabetes und atherosklerose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2006519193A true JP2006519193A (ja) | 2006-08-24 |
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| JP2006501892A Pending JP2006519199A (ja) | 2003-02-27 | 2004-02-19 | ２型糖尿病およびアテローム性動脈硬化症の治療のためのｐｐａｒモジュレーターとしての４−（３−（２−フェニル−オキサゾール−４−イルメトキシ）−シクロヘキシルオキシ）−ブタン酸誘導体および関連化合物 |
| JP2006501885A Pending JP2006519193A (ja) | 2003-02-27 | 2004-02-19 | ２型糖尿病およびアテローム性動脈硬化症の治療のためのｐｐａｒモジュレーターとしての３−メチル−２−（３−（２−フェニル−オキサゾール−４−イルメトキシ）−シクロヘキサンカルボニル−アミノ酪酸誘導体および関連化合物 |
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| JP2006501886A Pending JP2006519194A (ja) | 2003-02-27 | 2004-02-19 | ２型糖尿病およびアテローム性動脈硬化症の治療のためのｐｐａｒモジュレーターとしての３−（２−フェニル−オキサゾール−４−イルメトキシ）シクロヘキシルメトキシ酢酸誘導体および関連化合物 |
| JP2006501892A Pending JP2006519199A (ja) | 2003-02-27 | 2004-02-19 | ２型糖尿病およびアテローム性動脈硬化症の治療のためのｐｐａｒモジュレーターとしての４−（３−（２−フェニル−オキサゾール−４−イルメトキシ）−シクロヘキシルオキシ）−ブタン酸誘導体および関連化合物 |
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| DE102004038403B4 (de) * | 2004-08-07 | 2006-08-31 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten |
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| DE102004039533B4 (de) * | 2004-08-14 | 2006-09-28 | Sanofi-Aventis Deutschland Gmbh | Essigsäurederivate mit Cyclohexylmethoxy-Substituenten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
| DE102004060227B3 (de) | 2004-12-15 | 2006-07-20 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung von Oxazolen durch Kondensation von aromatischen Aldehyden mit α-Ketoximen zu N-Oxiden und nachfolgende Reaktion mit aktivierten Säurederivaten |
| GT200600218A (es) * | 2005-06-10 | 2007-03-28 | Formulación y proceso de compresión directa | |
| EP1931337B1 (en) | 2005-09-29 | 2013-10-23 | Sanofi | Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals |
| US8128969B2 (en) | 2006-08-10 | 2012-03-06 | Mimozax Co., Ltd. | Hypoglycemic composition containing acacia bark derivative |
| CN101801906A (zh) | 2007-08-16 | 2010-08-11 | 索尔维公司 | 制备4-氟取代的3-氧代-烷酸酯的方法 |
| CN101959875B (zh) * | 2008-02-29 | 2013-10-16 | 日产化学工业株式会社 | 噻吩化合物及其中间体的制造方法 |
| US7615661B2 (en) * | 2008-03-12 | 2009-11-10 | International Flavors & Fragrances Inc. | Thioester compounds and their use in fragrance or flavor applications |
| KR102450783B1 (ko) | 2017-12-13 | 2022-10-06 | 캐논 가부시끼가이샤 | 카트리지 |
| CN109810071B (zh) * | 2019-03-28 | 2023-04-21 | 中国科学院成都生物研究所 | 一种miRNA生物合成抑制剂 |
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-
2003
- 2003-02-27 DE DE10308355A patent/DE10308355A1/de not_active Withdrawn
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2004
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- 2004-02-19 RU RU2005130002/04A patent/RU2005130002A/ru not_active Application Discontinuation
- 2004-02-19 JP JP2006501886A patent/JP2006519194A/ja active Pending
- 2004-02-19 WO PCT/EP2004/001579 patent/WO2004076427A1/de active IP Right Grant
- 2004-02-19 EP EP04712490A patent/EP1599452B1/de not_active Expired - Lifetime
- 2004-02-19 ES ES04712494T patent/ES2326418T3/es not_active Expired - Lifetime
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- 2004-02-19 MX MXPA05008988A patent/MXPA05008988A/es active IP Right Grant
- 2004-02-19 DK DK04712503T patent/DK1599455T3/da active
- 2004-02-19 DE DE502004009690T patent/DE502004009690D1/de not_active Expired - Lifetime
- 2004-02-19 PT PT04712503T patent/PT1599455E/pt unknown
- 2004-02-19 BR BRPI0407907-8A patent/BRPI0407907A/pt not_active IP Right Cessation
- 2004-02-19 PL PL378437A patent/PL378437A1/pl not_active Application Discontinuation
- 2004-02-19 CN CNB2004800054769A patent/CN100439347C/zh not_active Expired - Fee Related
- 2004-02-19 DK DK04712494T patent/DK1599453T3/da active
- 2004-02-19 JP JP2006501892A patent/JP2006519199A/ja active Pending
- 2004-02-19 WO PCT/EP2004/001586 patent/WO2004076428A1/de active Application Filing
- 2004-02-19 KR KR1020057015995A patent/KR20050106461A/ko not_active Application Discontinuation
- 2004-02-19 AT AT04712494T patent/ATE430738T1/de not_active IP Right Cessation
- 2004-02-19 PT PT04712490T patent/PT1599452E/pt unknown
- 2004-02-19 EP EP04712494A patent/EP1599453B1/de not_active Expired - Lifetime
- 2004-02-19 BR BRPI0407758-0A patent/BRPI0407758A/pt not_active IP Right Cessation
- 2004-02-19 JP JP2006501885A patent/JP2006519193A/ja active Pending
- 2004-02-19 WO PCT/EP2004/001578 patent/WO2004076426A1/de active Application Filing
- 2004-02-19 DK DK04712490T patent/DK1599452T3/da active
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- 2004-02-19 RU RU2005129995/04A patent/RU2005129995A/ru not_active Application Discontinuation
- 2004-02-19 CN CNB2004800054379A patent/CN100439345C/zh not_active Expired - Fee Related
- 2004-02-19 RS YUP-2005/0594A patent/RS20050594A/sr unknown
- 2004-02-19 DE DE502004009453T patent/DE502004009453D1/de not_active Expired - Lifetime
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- 2004-02-19 PL PL377735A patent/PL377735A1/pl not_active Application Discontinuation
- 2004-02-19 CA CA002517386A patent/CA2517386A1/en not_active Abandoned
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- 2004-02-19 AT AT04712503T patent/ATE435217T1/de not_active IP Right Cessation
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999046232A1 (fr) * | 1998-03-10 | 1999-09-16 | Ono Pharmaceutical Co., Ltd. | Derives d'acide carboxylique et medicaments contenant ces derives comme principe actif |
| JP2002543065A (ja) * | 1999-04-28 | 2002-12-17 | アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Ｐｐａｐ受容体リガンドとしてのトリアリール酸誘導体 |
| WO2002016633A2 (en) * | 2000-08-11 | 2002-02-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods for identifying inhibitors of ubiquitin-mediated proteolysis of ikb |
| WO2002051820A1 (fr) * | 2000-12-25 | 2002-07-04 | Ono Pharmaceutical Co., Ltd. | Composes derives de dihydronaphtalene et medicaments utilisant ces composes comme ingredient actif |
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