JP2006516987A5 - - Google Patents

Download PDF

Info

Publication number
JP2006516987A5
JP2006516987A5 JP2006502243A JP2006502243A JP2006516987A5 JP 2006516987 A5 JP2006516987 A5 JP 2006516987A5 JP 2006502243 A JP2006502243 A JP 2006502243A JP 2006502243 A JP2006502243 A JP 2006502243A JP 2006516987 A5 JP2006516987 A5 JP 2006516987A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
formula
treatment
anemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006502243A
Other languages
English (en)
Japanese (ja)
Other versions
JP5390070B2 (ja
JP2006516987A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2004/000457 external-priority patent/WO2004069237A1/en
Publication of JP2006516987A publication Critical patent/JP2006516987A/ja
Publication of JP2006516987A5 publication Critical patent/JP2006516987A5/ja
Application granted granted Critical
Publication of JP5390070B2 publication Critical patent/JP5390070B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2006502243A 2003-02-07 2004-02-06 赤血球形成刺激薬としての中鎖脂肪酸、グリセリド、および類似体 Expired - Fee Related JP5390070B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44545403P 2003-02-07 2003-02-07
US60/445,454 2003-02-07
PCT/GB2004/000457 WO2004069237A1 (en) 2003-02-07 2004-02-06 Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis

Publications (3)

Publication Number Publication Date
JP2006516987A JP2006516987A (ja) 2006-07-13
JP2006516987A5 true JP2006516987A5 (enExample) 2007-01-18
JP5390070B2 JP5390070B2 (ja) 2014-01-15

Family

ID=32850990

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006502243A Expired - Fee Related JP5390070B2 (ja) 2003-02-07 2004-02-06 赤血球形成刺激薬としての中鎖脂肪酸、グリセリド、および類似体

Country Status (28)

Country Link
US (1) US9682054B2 (enExample)
EP (1) EP1592416B1 (enExample)
JP (1) JP5390070B2 (enExample)
KR (1) KR101120775B1 (enExample)
CN (1) CN100427081C (enExample)
AP (1) AP2005003367A0 (enExample)
AR (1) AR043120A1 (enExample)
AT (1) ATE419846T1 (enExample)
AU (1) AU2004210193B2 (enExample)
BR (1) BRPI0407276A (enExample)
CA (1) CA2515160C (enExample)
CY (1) CY1108963T1 (enExample)
DE (2) DE602004018902D1 (enExample)
DK (1) DK1592416T3 (enExample)
EA (1) EA009939B1 (enExample)
ES (1) ES2255467T3 (enExample)
IL (1) IL170057A (enExample)
JO (1) JO2705B1 (enExample)
MA (1) MA27664A1 (enExample)
MX (1) MXPA05008382A (enExample)
MY (1) MY140913A (enExample)
NO (1) NO334085B1 (enExample)
NZ (1) NZ541593A (enExample)
PT (1) PT1592416E (enExample)
SI (1) SI1592416T1 (enExample)
TN (1) TNSN05189A1 (enExample)
WO (1) WO2004069237A1 (enExample)
ZA (1) ZA200506246B (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1900364T3 (da) * 2001-04-18 2014-01-13 Prometic Biosciences Inc Fedtsyrer, glycerider og analoger med medium kædelængde som neutrofile overlevelses- og aktiveringsfaktorer
CA2563533C (en) * 2004-04-15 2013-10-01 Shmuel A. Ben-Sasson Compositions capable of facilitating penetration across a biological barrier
US20070219131A1 (en) * 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
JP2008507288A (ja) 2004-07-23 2008-03-13 アクセルロン ファーマ インコーポレーテッド ＡｃｔＲＩＩ受容体ポリペプチド、方法、および組成物
AP2007003939A0 (en) * 2004-09-03 2007-04-30 Prometic Biosciences Inc Substituted purinyl derivatives with immunomodulator and chemoprotective activity and use alone or with medium-chain length fatty acids or glycerides
EA200700741A1 (ru) 2004-10-01 2007-08-31 Прометик Байосайенсиз Инк. Жирные спирты со средней длиной цепи как стимуляторы гематопоэза
US8071580B2 (en) * 2004-10-01 2011-12-06 Prometic Biosciences Inc. Medium-chain length fatty alcohols as stimulators of hematopoiesis
BRPI0618947B1 (pt) 2005-11-23 2022-07-19 Acceleron Pharma Inc Polipeptídeo actriia que se liga à ativina, polinucleotídeo isolado, polinucleotídeo recombinante, métodopara preparar um polipeptídeo actriia que se liga à ativina, preparação farmacêutica e uso de uma proteína de fusão actriia-fc para promover o crescimento ósseo e inibir a ressorção óssea
US8128933B2 (en) 2005-11-23 2012-03-06 Acceleron Pharma, Inc. Method of promoting bone growth by an anti-activin B antibody
US8895016B2 (en) 2006-12-18 2014-11-25 Acceleron Pharma, Inc. Antagonists of activin-actriia and uses for increasing red blood cell levels
TWI584815B (zh) 2007-02-01 2017-06-01 艾瑟勒朗法瑪公司 活化素-ＡｃｔＲＩＩａ拮抗劑及其治療或預防乳癌之用途
TW201627320A (zh) 2007-02-02 2016-08-01 艾瑟勒朗法瑪公司 衍生自ＡｃｔＲＩＩＢ的變體與其用途
MX2009008510A (es) 2007-02-09 2010-01-15 Acceleron Pharma Inc Antagonistas de activina-actriia y usos para promover el crecimiento de huesos en pacientes con cancer.
CA2699936A1 (en) 2007-09-18 2009-03-26 Acceleron Pharma Inc. Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion
US9532962B2 (en) 2007-11-02 2017-01-03 Prometic Pharma Smt Limited Medium-chain length fatty acids and glycerides as nephroprotection agents
JP5473937B2 (ja) * 2007-12-19 2014-04-16 プロメティック・バイオサイエンシーズ・インコーポレイテッド 膵臓癌の治療のためのゲムシタビンと併用した中鎖脂肪酸、その塩およびトリグリセリド
US8216997B2 (en) 2008-08-14 2012-07-10 Acceleron Pharma, Inc. Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
DK3750552T5 (da) 2008-08-14 2024-08-26 Acceleron Pharma Inc Gdf-fælder
RU2678833C2 (ru) * 2008-09-17 2019-02-04 Киазма Инк. Фармацевтические композиции и соответствующие способы доставки
MX355042B (es) 2009-06-08 2018-04-02 Acceleon Pharma Inc Metodos para aumentar adipositos termogenicos.
CN107267520A (zh) 2009-06-12 2017-10-20 阿塞勒隆制药公司 截短的actriib‑fc融合蛋白
KR102170682B1 (ko) * 2009-08-13 2020-10-28 악셀레론 파마 인코포레이티드 적혈구 수준을 증가시키기 위한 ｇｄｆ 트랩과 에리트로포이에틴 수용체 활성인자의 병용
ES2658292T3 (es) 2009-11-17 2018-03-09 Acceleron Pharma, Inc. Proteínas ActRIIB y variantes y usos de las mismas con respecto a la inducción de la utrofina para el tratamiento de la distrofia muscular
CA2817008A1 (en) 2010-11-08 2012-05-18 Acceleron Pharma Inc. Actriia binding agents and uses thereof
TWI572352B (zh) * 2012-03-01 2017-03-01 波麥堤克藥學Ｓｍｔ有限公司 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法
RU2678117C2 (ru) 2012-11-02 2019-01-23 Селджин Корпорейшн Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений
CN102973922B (zh) * 2012-12-18 2016-02-03 华东理工大学 一种融合蛋白的应用
CN114699529A (zh) 2014-06-13 2022-07-05 阿塞勒隆制药公司 用于治疗溃疡的方法和组合物
MA41052A (fr) 2014-10-09 2017-08-15 Celgene Corp Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii
EP3227675B1 (en) 2014-12-03 2023-03-15 Celgene Corporation Activin-actrii antagonists and uses for treating myelodysplastic syndrome
SI3253401T1 (sl) 2015-02-03 2025-07-31 Amryt Endo, Inc. Zdravljenje akromegalije z oralnim oktreotidom
US20170021029A1 (en) * 2015-04-15 2017-01-26 Jeffrey Charles Raber Topical formulations and uses
MA53188A1 (fr) 2018-10-11 2021-12-31 Basf As Composés aromatiques et leurs utilisations pharmaceutiques
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871768A (en) 1984-07-12 1989-10-03 New England Deaconess Hospital Corporation Dietary supplement utilizing ω-3/medium chain trigylceride mixtures
US7307166B1 (en) 1987-10-28 2007-12-11 Wellstat Therapeutics Corporation Oxpurine nucleosides and their congeners, and acyl, derivatives thereof, for improvement of hematopoiesis
US5011852A (en) 1988-07-25 1991-04-30 Applied Analytical Industries, Inc. Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs
JP3014119B2 (ja) * 1990-05-28 2000-02-28 雪印乳業株式会社 直腸投与用赤血球造血剤
JP3249147B2 (ja) 1990-06-01 2002-01-21 キリン−アムジエン・インコーポレーテツド 生理活性蛋白含有経口製剤
ATE147976T1 (de) * 1991-01-15 1997-02-15 Hemosphere Inc Protein nanomatrizen und verfahren zur herstellung
JPH05163160A (ja) 1991-12-13 1993-06-29 Snow Brand Milk Prod Co Ltd 免疫低下に伴う感染症の予防及び治療用栄養剤
US5214035A (en) 1992-04-16 1993-05-25 Hoechst-Roussel Agri-Vet Company Thixotropic formulations
US5318781A (en) * 1993-04-06 1994-06-07 Hoffmann-La Roche Inc. Absorption enhancement of antibiotics
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
AU7082694A (en) * 1994-05-10 1995-11-29 Kitasato Institute, The Hematopoietic stem cell proliferation accelerator
US5470861A (en) 1994-08-04 1995-11-28 Hoffmann-La Roche Inc. Method of promoting hair growth
US5549905A (en) 1994-10-18 1996-08-27 Clintec Nutrition Co. Enternal composition for pediatric patients
JPH08208510A (ja) 1994-11-03 1996-08-13 F Hoffmann La Roche Ag インターフェロン組成物
GB9516268D0 (en) 1995-08-08 1995-10-11 Danbiosyst Uk Compositiion for enhanced uptake of polar drugs from the colon
AUPN933396A0 (en) 1996-04-17 1996-05-09 Pfizer Pty Limited Non-aqueuos oral-drench compositions containing avermectin compounds
US5851534A (en) 1996-05-03 1998-12-22 Dynagen, Inc. Methods for prevention and/or treatment of neutropenia
JPH10265380A (ja) 1997-03-17 1998-10-06 Bristol Myers Squibb Co 抗ガン剤
EP1009383A1 (en) * 1997-09-04 2000-06-21 Biozone Laboratories, Inc. Oral liposomal delivery system
AU752802C (en) * 1997-11-14 2006-04-13 Pacira Pharmaceuticals, Inc. Production of multivesicular liposomes
CA2311124A1 (en) 1997-11-19 1999-05-27 Hercules Incorporated Fluidized polymer suspensions of cationic polysaccharides in emollients and use thereof in preparing personal care compositions
DE69833333T2 (de) * 1997-11-20 2006-10-19 Jhon, Gil Ja Pharmazeutische zusammensetzung enthaltend geweihextrakte von cervus nippon mit wachstumsstimulierender aktivität auf hematopoietische stammzellen und megakaryozyten
PT937456E (pt) * 1998-02-23 2004-10-29 Cilag Ag Int Dispersao lipossomal de eritropoietina
KR20010041696A (ko) 1998-03-11 2001-05-25 그레랑 파마수티컬 가부시키가이샤 발포성 장용(腸溶) 제제
US6267985B1 (en) 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
CA2385989A1 (en) 1999-09-27 2001-04-05 Andrew Nienstedt Compositions of tocol-soluble therapeutics
US6835750B1 (en) 2000-05-01 2004-12-28 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
DE60123603T2 (de) 2000-06-14 2007-08-16 William Leslie Diss Porter Lipide zur änderung des abwehrsystems
US6967028B2 (en) 2000-07-31 2005-11-22 Mainelab Prolonged release microspheres for injectable administration
IL142535A0 (en) 2001-04-11 2002-03-10 Yeda Res & Dev Pharmaceutical compositions for the treatment of inflammation
DK1900364T3 (da) * 2001-04-18 2014-01-13 Prometic Biosciences Inc Fedtsyrer, glycerider og analoger med medium kædelængde som neutrofile overlevelses- og aktiveringsfaktorer
US20040052836A1 (en) 2002-09-13 2004-03-18 Li Luk Chiu Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life
US6725510B1 (en) 2003-04-25 2004-04-27 Almetta Clyburn Inclining coffin
PL1648851T3 (pl) 2003-07-25 2007-09-28 Prometic Biosciences Inc Wytwarzanie soli średniołańcuchowych kwasów tłuszczowych z metalami
AP2007003939A0 (en) 2004-09-03 2007-04-30 Prometic Biosciences Inc Substituted purinyl derivatives with immunomodulator and chemoprotective activity and use alone or with medium-chain length fatty acids or glycerides
US8071580B2 (en) 2004-10-01 2011-12-06 Prometic Biosciences Inc. Medium-chain length fatty alcohols as stimulators of hematopoiesis

Similar Documents

Publication Publication Date Title
ES2255467T1 (es) Acidos grasos de cadena media, gliceridos y analogos como estimuladores de la eritropoyesis.
ES2996688T3 (en) Fatty acid derivatives for treating non-alcoholic steatohepatitis
RU2010122302A (ru) Жирные кислоты и глицериды со средней длиной цепи в качестве нефропротективных средств
US20130059820A1 (en) Inositol pyrophosphates, and methods of use thereof
KR102265409B1 (ko) 지질 화합물을 이용한 치료방법
JP2011502174A5 (enExample)
JP2014240429A (ja) ビニル置換脂肪酸
US6610702B2 (en) Ammonium salts of inositol hexaphosphate, and uses thereof
JP5552314B2 (ja) 新規脂質化合物
US20230321022A1 (en) Reversibly protected thiolated electrophilic fatty acids as prodrugs
JP2024511208A (ja) 治療薬のバイオアベイラビリティを改善した組成物
JP2010509204A5 (enExample)
JP2012522841A5 (enExample)
WO2016130417A1 (en) Omega-3 fatty acid prodrug compounds and uses thereof
KR20250060955A (ko) 페롭토시스를 유도하는 조성물 및 방법
JP2011502113A (ja) 新規のｄｈａ誘導体およびその医薬品としての用途
US20130261099A1 (en) Fatty Acid Inhibitors
US20150374660A1 (en) Ascorbate Esters of Omega-3 Fatty Acids and Their Formulations and Uses
KR20070108383A (ko) 지질 저하성 화합물
JP7758319B2 (ja) 骨外組織における骨形成関連因子又は石灰化関連因子の発現抑制剤
AU748861B2 (en) Method of mitigating the adverse effects of interleukin-2
KR20180111791A (ko) 신규 비스포스폰산 화합물
RU2820995C2 (ru) Структурно усиленные жирные кислоты, содержащие кислород, для лечения неалкогольного стеатогепатита
WO2014160936A2 (en) Thiazolidinediones of omega-3 polyunsaturated acids as new insulin sensitizers for treating type2 diabetes
JP2011505408A (ja) ３−（２，２，２−トリメチルヒドラジニウム）プロピオナートのフマル酸水素塩及びリン酸二水素塩を医療に用いる方法