KR101120775B1 - 적혈구생성의 자극제로서의 중쇄 지방산, 글리세리드 및유사체 - Google Patents

적혈구생성의 자극제로서의 중쇄 지방산, 글리세리드 및유사체 Download PDF

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KR101120775B1
KR101120775B1 KR1020057014499A KR20057014499A KR101120775B1 KR 101120775 B1 KR101120775 B1 KR 101120775B1 KR 1020057014499 A KR1020057014499 A KR 1020057014499A KR 20057014499 A KR20057014499 A KR 20057014499A KR 101120775 B1 KR101120775 B1 KR 101120775B1
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pharmaceutical composition
anemia
treatment
compound
cells
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Korean (ko)
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KR20050118671A (ko
Inventor
크리스토퍼 페니
린 개그논
피에르 라우린
보울로스 자캐리
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프로메틱 바이오사이언시즈 인코포레이티드
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020057014499A 2003-02-07 2004-02-06 적혈구생성의 자극제로서의 중쇄 지방산, 글리세리드 및유사체 Expired - Fee Related KR101120775B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44545403P 2003-02-07 2003-02-07
US60/445454 2003-02-07
PCT/GB2004/000457 WO2004069237A1 (en) 2003-02-07 2004-02-06 Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis

Publications (2)

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KR20050118671A KR20050118671A (ko) 2005-12-19
KR101120775B1 true KR101120775B1 (ko) 2012-04-18

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US (1) US9682054B2 (enExample)
EP (1) EP1592416B1 (enExample)
JP (1) JP5390070B2 (enExample)
KR (1) KR101120775B1 (enExample)
CN (1) CN100427081C (enExample)
AP (1) AP2005003367A0 (enExample)
AR (1) AR043120A1 (enExample)
AT (1) ATE419846T1 (enExample)
AU (1) AU2004210193B2 (enExample)
BR (1) BRPI0407276A (enExample)
CA (1) CA2515160C (enExample)
CY (1) CY1108963T1 (enExample)
DE (2) DE602004018902D1 (enExample)
DK (1) DK1592416T3 (enExample)
EA (1) EA009939B1 (enExample)
ES (1) ES2255467T3 (enExample)
IL (1) IL170057A (enExample)
JO (1) JO2705B1 (enExample)
MA (1) MA27664A1 (enExample)
MX (1) MXPA05008382A (enExample)
MY (1) MY140913A (enExample)
NO (1) NO334085B1 (enExample)
NZ (1) NZ541593A (enExample)
PT (1) PT1592416E (enExample)
SI (1) SI1592416T1 (enExample)
TN (1) TNSN05189A1 (enExample)
WO (1) WO2004069237A1 (enExample)
ZA (1) ZA200506246B (enExample)

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US20070219131A1 (en) * 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
CA2563533C (en) * 2004-04-15 2013-10-01 Shmuel A. Ben-Sasson Compositions capable of facilitating penetration across a biological barrier
EP3059245B1 (en) 2004-07-23 2018-11-07 Acceleron Pharma Inc. Actrii receptor antagonistic antibodies
CN101080229A (zh) * 2004-09-03 2007-11-28 普罗米蒂克生物科学公司 免疫调节剂取代的嘌呤基衍生物和其化学保护活性以及其单独使用或与中链脂肪酸或甘油酯联用的用途
US8071580B2 (en) 2004-10-01 2011-12-06 Prometic Biosciences Inc. Medium-chain length fatty alcohols as stimulators of hematopoiesis
CA2582262C (en) * 2004-10-01 2013-01-08 Prometic Biosciences Inc. Medium-chain length fatty alcohols as stimulators of hematopoiesis
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TWI782836B (zh) 2007-02-02 2022-11-01 美商艾瑟勒朗法瑪公司 衍生自ActRIIB的變體與其用途
TWI606062B (zh) 2007-02-09 2017-11-21 艾瑟勒朗法瑪公司 包含ActRIIa-Fc融合蛋白的醫藥組合物;ActRIIa-Fc融合蛋白於治療或預防與癌症相關的骨質流失之用途;ActRIIa-Fc融合蛋白於治療或預防多發性骨髓瘤之用途
WO2009038745A1 (en) 2007-09-18 2009-03-26 Acceleron Pharma Inc. Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion
RU2519215C2 (ru) * 2007-11-02 2014-06-10 Прометик Байосайенсиз Инк. Жирные кислоты и глицериды со средней длиной цепи в качестве нефропротективных средств
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HRP20191109T1 (hr) 2008-08-14 2019-09-20 Acceleron Pharma Inc. Gdf klopke za uporabu u liječenju anemije
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KR101882521B1 (ko) * 2009-08-13 2018-07-27 악셀레론 파마 인코포레이티드 적혈구 수준을 증가시키기 위한 gdf 트랩과 에리트로포이에틴 수용체 활성인자의 병용
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TWI572352B (zh) * 2012-03-01 2017-03-01 波麥堤克藥學Smt有限公司 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法
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Also Published As

Publication number Publication date
EA009939B1 (ru) 2008-04-28
EA200501267A1 (ru) 2006-02-24
DE602004018902D1 (de) 2009-02-26
EP1592416A1 (en) 2005-11-09
MA27664A1 (fr) 2005-12-01
MY140913A (en) 2010-01-29
NO334085B1 (no) 2013-12-09
DK1592416T3 (da) 2009-04-20
IL170057A (en) 2011-09-27
SI1592416T1 (sl) 2009-06-30
PT1592416E (pt) 2009-04-03
JP2006516987A (ja) 2006-07-13
AR043120A1 (es) 2005-07-20
AP2005003367A0 (en) 2005-09-30
CN1753665A (zh) 2006-03-29
CA2515160A1 (en) 2004-08-19
ZA200506246B (en) 2006-12-27
NO20053994L (no) 2005-10-06
JP5390070B2 (ja) 2014-01-15
ATE419846T1 (de) 2009-01-15
AU2004210193B2 (en) 2007-07-12
ES2255467T3 (es) 2009-05-01
AU2004210193A1 (en) 2004-08-19
DE04708802T1 (de) 2006-06-22
MXPA05008382A (es) 2005-11-04
CN100427081C (zh) 2008-10-22
US20060128800A1 (en) 2006-06-15
US9682054B2 (en) 2017-06-20
ES2255467T1 (es) 2006-07-01
EP1592416B1 (en) 2009-01-07
NO20053994D0 (no) 2005-08-26
CA2515160C (en) 2013-01-08
CY1108963T1 (el) 2014-07-02
WO2004069237A1 (en) 2004-08-19
KR20050118671A (ko) 2005-12-19
NZ541593A (en) 2009-05-31
JO2705B1 (ar) 2014-03-15
TNSN05189A1 (en) 2007-06-11
BRPI0407276A (pt) 2006-01-31

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