MA27664A1 - Acides gras a chaine moyenne, glycerides et analogues utilises en tant que stimulateurs de l'erythropoiese - Google Patents
Acides gras a chaine moyenne, glycerides et analogues utilises en tant que stimulateurs de l'erythropoieseInfo
- Publication number
- MA27664A1 MA27664A1 MA28479A MA28479A MA27664A1 MA 27664 A1 MA27664 A1 MA 27664A1 MA 28479 A MA28479 A MA 28479A MA 28479 A MA28479 A MA 28479A MA 27664 A1 MA27664 A1 MA 27664A1
- Authority
- MA
- Morocco
- Prior art keywords
- erythroposis
- stimulators
- glycerides
- fatty acids
- chain fatty
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne l'utilisation d'une composition comprenant un composé représenté par la formule I, II, IIa, III ou IIIa; ou une combinaison de celles-ci, dans lesquelles chaque R1 représente indépendamment alkyle C7-11; A et B représentent indépendamment H ou CO-R1; R2 représente H ou alkyle C1-4; M représente un monocation (k=1) ou un dication (k=2) métallique ; Y vaut 0 ou NH; et Z vaut 0, NH, CH2O ou une liaison; pour la fabrication d'un médicament pour la stimulation de l'érythropoïèse. La composition comprend de préférence de l'érythropoïétine humaine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44545403P | 2003-02-07 | 2003-02-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA27664A1 true MA27664A1 (fr) | 2005-12-01 |
Family
ID=32850990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA28479A MA27664A1 (fr) | 2003-02-07 | 2005-09-05 | Acides gras a chaine moyenne, glycerides et analogues utilises en tant que stimulateurs de l'erythropoiese |
Country Status (28)
Country | Link |
---|---|
US (1) | US9682054B2 (fr) |
EP (1) | EP1592416B1 (fr) |
JP (1) | JP5390070B2 (fr) |
KR (1) | KR101120775B1 (fr) |
CN (1) | CN100427081C (fr) |
AP (1) | AP2005003367A0 (fr) |
AR (1) | AR043120A1 (fr) |
AT (1) | ATE419846T1 (fr) |
AU (1) | AU2004210193B2 (fr) |
BR (1) | BRPI0407276A (fr) |
CA (1) | CA2515160C (fr) |
CY (1) | CY1108963T1 (fr) |
DE (2) | DE602004018902D1 (fr) |
DK (1) | DK1592416T3 (fr) |
EA (1) | EA009939B1 (fr) |
ES (1) | ES2255467T3 (fr) |
IL (1) | IL170057A (fr) |
JO (1) | JO2705B1 (fr) |
MA (1) | MA27664A1 (fr) |
MX (1) | MXPA05008382A (fr) |
MY (1) | MY140913A (fr) |
NO (1) | NO334085B1 (fr) |
NZ (1) | NZ541593A (fr) |
PT (1) | PT1592416E (fr) |
SI (1) | SI1592416T1 (fr) |
TN (1) | TNSN05189A1 (fr) |
WO (1) | WO2004069237A1 (fr) |
ZA (1) | ZA200506246B (fr) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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JP5026655B2 (ja) | 2001-04-18 | 2012-09-12 | プロメティック、バイオサイエンシーズ、インコーポレーテッド | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
MXPA06011871A (es) * | 2004-04-15 | 2007-10-08 | Chiasma Inc | Composiciones capaces de facilitar la penetracion a traves de una barrera biologica. |
EP2332977B1 (fr) | 2004-07-23 | 2015-11-25 | Acceleron Pharma Inc. | Polypeptides du récepteur AvtRII |
EA200700543A1 (ru) * | 2004-09-03 | 2007-10-26 | Прометик Байосайенсиз Инк. | Замещенные пуринилпроизводные с иммуномодулирующей и химиозащитной активностью и их применение как таковых или с жирными кислотами со средней длиной цепи или глицеридами |
JP4948414B2 (ja) * | 2004-10-01 | 2012-06-06 | プロメティック バイオサイエンシズ インコーポレーテッド | 造血刺激剤としての中間鎖長脂肪アルコール |
US8071580B2 (en) * | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
DK1973559T3 (da) | 2005-11-23 | 2013-03-25 | Acceleron Pharma Inc | Activin-ActRIIa antagonister samt anvendelser til fremme af knoglevækst |
US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
CN103920139B (zh) | 2007-02-01 | 2018-02-02 | 阿塞勒隆制药公司 | 活化素‑actriia拮抗剂及在治疗或预防乳腺癌中的用途 |
TWI782836B (zh) | 2007-02-02 | 2022-11-01 | 美商艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
TWI459963B (zh) | 2007-02-09 | 2014-11-11 | Acceleron Pharma Inc | 包含ActRIIa-Fc融合蛋白的醫藥組合物;ActRIIa-Fc融合蛋白於治療或預防與癌症相關的骨質流失之用途;ActRIIa-Fc融合蛋白於治療或預防多發性骨髓瘤之用途 |
CN107412734A (zh) | 2007-09-18 | 2017-12-01 | 阿塞勒隆制药公司 | 活化素‑actriia拮抗剂和减少或抑制fsh分泌的用途 |
EP2299998B1 (fr) * | 2007-11-02 | 2018-01-03 | Prometic Pharma Smt Limited | Acides gras à chaînes de longueur moyenne et glycérides agents néphroprotecteurs |
NZ586249A (en) * | 2007-12-19 | 2012-05-25 | Prometic Biosciences Inc | A combination of medium-chain length fatty acids, salts or triglycerides, gemcitabine, and optionally erlotinib, for the treatment of pancreatic cancer |
TWI626945B (zh) | 2008-08-14 | 2018-06-21 | 艾瑟勒朗法瑪公司 | 使用gdf阱以增加紅血球水平 |
US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
WO2010032140A2 (fr) | 2008-09-17 | 2010-03-25 | Chiasma Inc. | Préparations pharmaceutiques et méthodes associées d'administration |
EP2440576A4 (fr) | 2009-06-08 | 2013-11-20 | Acceleron Pharma Inc | Procédé visant à augmenter le nombre d'adipocytes thermogènes |
KR20210034684A (ko) | 2009-06-12 | 2021-03-30 | 악셀레론 파마 인코포레이티드 | 절두된 ActRIIB-FC 융합 단백질 |
EP3838919A1 (fr) * | 2009-08-13 | 2021-06-23 | Acceleron Pharma Inc. | Utilisation combinée de pièges gdf et activateurs du récepteur de l'érythropoïétine pour augmenter les taux d'érythrocytes |
EP2501400B1 (fr) | 2009-11-17 | 2017-11-01 | Acceleron Pharma, Inc. | Protéines actriib et variants et utilisations de celles-ci se rapportant à l'induction de l'utrophine pour une thérapie de la dystrophie musculaire |
JP2014502260A (ja) | 2010-11-08 | 2014-01-30 | アクセルロン ファーマ, インコーポレイテッド | Actriia結合剤およびその使用 |
TWI572352B (zh) * | 2012-03-01 | 2017-03-01 | 波麥堤克藥學Smt有限公司 | 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法 |
KR102279522B1 (ko) | 2012-11-02 | 2021-07-19 | 셀진 코포레이션 | 골 및 다른 장애를 치료하기 위한 액티빈-actrii 길항제 및 용도 |
CN102973922B (zh) * | 2012-12-18 | 2016-02-03 | 华东理工大学 | 一种融合蛋白的应用 |
EP3154566B1 (fr) | 2014-06-13 | 2022-08-03 | Acceleron Pharma Inc. | Antagoniste actrii pour le traitement et la prevention d'un ulcere cutane chez un sujet ayant l'anemie |
MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
HUE062189T2 (hu) | 2014-12-03 | 2023-09-28 | Celgene Corp | Aktivin-ACTRII-antagonisták és alkalmazások mielodiszpláziás szindróma kezelésére |
MA41462A (fr) | 2015-02-03 | 2021-05-12 | Chiasma Inc | Méthode de traitement de maladies |
US20170021029A1 (en) * | 2015-04-15 | 2017-01-26 | Jeffrey Charles Raber | Topical formulations and uses |
US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
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DE69910183T2 (de) | 1998-03-11 | 2004-06-03 | Grelan Pharmaceutical Co., Ltd., Hamura | Darmlösliche sprudelnde zusammensetzungen |
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CA2385989A1 (fr) | 1999-09-27 | 2001-04-05 | Andrew Nienstedt | Compositions de composes therapeutiques solubles dans le tocol |
US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
DE60123603T2 (de) | 2000-06-14 | 2007-08-16 | William Leslie Diss Porter | Lipide zur änderung des abwehrsystems |
US6967028B2 (en) | 2000-07-31 | 2005-11-22 | Mainelab | Prolonged release microspheres for injectable administration |
IL142535A0 (en) | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of inflammation |
JP5026655B2 (ja) | 2001-04-18 | 2012-09-12 | プロメティック、バイオサイエンシーズ、インコーポレーテッド | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
US20040052836A1 (en) | 2002-09-13 | 2004-03-18 | Li Luk Chiu | Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life |
US6725510B1 (en) | 2003-04-25 | 2004-04-27 | Almetta Clyburn | Inclining coffin |
KR101120813B1 (ko) | 2003-07-25 | 2012-03-23 | 프로메틱 바이오사이언시즈 인코포레이티드 | 중-쇄 지방산 금속염의 제조 방법 |
EA200700543A1 (ru) | 2004-09-03 | 2007-10-26 | Прометик Байосайенсиз Инк. | Замещенные пуринилпроизводные с иммуномодулирующей и химиозащитной активностью и их применение как таковых или с жирными кислотами со средней длиной цепи или глицеридами |
US8071580B2 (en) | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
-
2004
- 2004-02-06 ES ES04708802T patent/ES2255467T3/es not_active Expired - Lifetime
- 2004-02-06 CA CA2515160A patent/CA2515160C/fr not_active Expired - Fee Related
- 2004-02-06 DK DK04708802T patent/DK1592416T3/da active
- 2004-02-06 EP EP04708802A patent/EP1592416B1/fr not_active Expired - Lifetime
- 2004-02-06 AU AU2004210193A patent/AU2004210193B2/en not_active Ceased
- 2004-02-06 SI SI200431064T patent/SI1592416T1/sl unknown
- 2004-02-06 WO PCT/GB2004/000457 patent/WO2004069237A1/fr active IP Right Grant
- 2004-02-06 DE DE602004018902T patent/DE602004018902D1/de not_active Expired - Lifetime
- 2004-02-06 AP AP2005003367A patent/AP2005003367A0/xx unknown
- 2004-02-06 JP JP2006502243A patent/JP5390070B2/ja not_active Expired - Fee Related
- 2004-02-06 EA EA200501267A patent/EA009939B1/ru not_active IP Right Cessation
- 2004-02-06 ZA ZA200506246A patent/ZA200506246B/en unknown
- 2004-02-06 AT AT04708802T patent/ATE419846T1/de active
- 2004-02-06 CN CNB200480004978XA patent/CN100427081C/zh not_active Expired - Fee Related
- 2004-02-06 MX MXPA05008382A patent/MXPA05008382A/es active IP Right Grant
- 2004-02-06 BR BR0407276-6A patent/BRPI0407276A/pt not_active Application Discontinuation
- 2004-02-06 NZ NZ541593A patent/NZ541593A/xx not_active IP Right Cessation
- 2004-02-06 DE DE04708802T patent/DE04708802T1/de active Pending
- 2004-02-06 PT PT04708802T patent/PT1592416E/pt unknown
- 2004-02-06 US US10/544,350 patent/US9682054B2/en active Active
- 2004-02-06 KR KR1020057014499A patent/KR101120775B1/ko active IP Right Grant
- 2004-02-06 AR ARP040100385A patent/AR043120A1/es not_active Application Discontinuation
- 2004-02-07 MY MYPI20040371A patent/MY140913A/en unknown
- 2004-02-24 JO JOP/2004/0017A patent/JO2705B1/ar active
-
2005
- 2005-08-03 TN TNP2005000189A patent/TNSN05189A1/en unknown
- 2005-08-03 IL IL170057A patent/IL170057A/en active IP Right Grant
- 2005-08-26 NO NO20053994A patent/NO334085B1/no not_active IP Right Cessation
- 2005-09-05 MA MA28479A patent/MA27664A1/fr unknown
-
2009
- 2009-04-06 CY CY20091100397T patent/CY1108963T1/el unknown
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