DE3871160D1 - Prostaglandinderivate, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung. - Google Patents
Prostaglandinderivate, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung.Info
- Publication number
- DE3871160D1 DE3871160D1 DE8888300415T DE3871160T DE3871160D1 DE 3871160 D1 DE3871160 D1 DE 3871160D1 DE 8888300415 T DE8888300415 T DE 8888300415T DE 3871160 T DE3871160 T DE 3871160T DE 3871160 D1 DE3871160 D1 DE 3871160D1
- Authority
- DE
- Germany
- Prior art keywords
- derivatives
- prostagland
- production
- side chain
- pharmaceutical application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 125000004043 oxo group Chemical group O=* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP940687 | 1987-01-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3871160D1 true DE3871160D1 (de) | 1992-06-25 |
Family
ID=11719530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8888300415T Expired - Fee Related DE3871160D1 (de) | 1987-01-19 | 1988-01-19 | Prostaglandinderivate, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4981872A (de) |
| EP (1) | EP0276124B1 (de) |
| KR (1) | KR930006200B1 (de) |
| AT (1) | ATE76402T1 (de) |
| CA (1) | CA1326021C (de) |
| DE (1) | DE3871160D1 (de) |
| ES (1) | ES2041785T3 (de) |
| GR (1) | GR3005153T3 (de) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU511711B2 (en) * | 1976-12-30 | 1980-09-04 | Upjohn Company, The | 6-Oxo and 5, 6-Dihalo prostaglandin analogues |
| US4202822A (en) * | 1977-12-08 | 1980-05-13 | American Cyanamid Company | 1-Hydroxymethyl-1-oxo-prostane derivatives of the F1 series |
| US4338252A (en) * | 1979-09-27 | 1982-07-06 | American Cyanamid Company | 1-Descarboxy-1-ketoester (ketoacid)-prostaglandins |
| JPS6033430B2 (ja) * | 1980-05-12 | 1985-08-02 | 小野薬品工業株式会社 | プロスタグランジン類似化合物 |
| JPH07116134B2 (ja) * | 1987-01-08 | 1995-12-13 | 帝人株式会社 | ５−オキソプロスタグランジンｅ▲下１▼類及びその製法 |
-
1988
- 1988-01-15 US US07/144,878 patent/US4981872A/en not_active Expired - Fee Related
- 1988-01-19 EP EP88300415A patent/EP0276124B1/de not_active Expired - Lifetime
- 1988-01-19 KR KR1019880000372A patent/KR930006200B1/ko not_active IP Right Cessation
- 1988-01-19 CA CA000556820A patent/CA1326021C/en not_active Expired - Fee Related
- 1988-01-19 ES ES198888300415T patent/ES2041785T3/es not_active Expired - Lifetime
- 1988-01-19 AT AT88300415T patent/ATE76402T1/de not_active IP Right Cessation
- 1988-01-19 DE DE8888300415T patent/DE3871160D1/de not_active Expired - Fee Related
-
1992
- 1992-07-13 GR GR920401498T patent/GR3005153T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0276124A2 (de) | 1988-07-27 |
| GR3005153T3 (de) | 1993-05-24 |
| US4981872A (en) | 1991-01-01 |
| KR930006200B1 (ko) | 1993-07-08 |
| CA1326021C (en) | 1994-01-11 |
| ATE76402T1 (de) | 1992-06-15 |
| EP0276124B1 (de) | 1992-05-20 |
| ES2041785T3 (es) | 1993-12-01 |
| KR880008984A (ko) | 1988-09-13 |
| EP0276124A3 (en) | 1989-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |