ATE48611T1 - Griseolinsaeurederivate, ihre herstellung und ihre verwendung. - Google Patents
Griseolinsaeurederivate, ihre herstellung und ihre verwendung.Info
- Publication number
- ATE48611T1 ATE48611T1 AT86303000T AT86303000T ATE48611T1 AT E48611 T1 ATE48611 T1 AT E48611T1 AT 86303000 T AT86303000 T AT 86303000T AT 86303000 T AT86303000 T AT 86303000T AT E48611 T1 ATE48611 T1 AT E48611T1
- Authority
- AT
- Austria
- Prior art keywords
- griseolinsic
- acid derivatives
- production
- acid
- replacing
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- IAPZXUKYTCQQFE-QZKDJMESSA-N (2r,3r,3as,5s)-2-(6-aminopurin-9-yl)-5-[carboxy(hydroxy)methyl]-3-hydroxy-3,3a-dihydro-2h-furo[3,2-b]furan-5-carboxylic acid Chemical class NC1=NC=NC2=C1N=CN2[C@H]1[C@H](O)[C@@H]2O[C@](C(O)=O)(C(O)C(O)=O)C=C2O1 IAPZXUKYTCQQFE-QZKDJMESSA-N 0.000 abstract 3
- IAPZXUKYTCQQFE-UHFFFAOYSA-N Griseolic acid Natural products NC1=NC=NC2=C1N=CN2C1C(O)C2OC(C(O)=O)(C(O)C(O)=O)C=C2O1 IAPZXUKYTCQQFE-UHFFFAOYSA-N 0.000 abstract 2
- GFFGJBXGBJISGV-UHFFFAOYSA-N adenyl group Chemical group N1=CN=C2N=CNC2=C1N GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 abstract 2
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 abstract 1
- 150000003212 purines Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8213285 | 1985-04-19 | ||
| JP9198985 | 1985-04-27 | ||
| JP9198785 | 1985-04-27 | ||
| EP86303000A EP0214708B1 (de) | 1985-04-19 | 1986-04-21 | Griseolinsäurederivate, ihre Herstellung und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE48611T1 true ATE48611T1 (de) | 1989-12-15 |
Family
ID=27441040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86303000T ATE48611T1 (de) | 1985-04-19 | 1986-04-21 | Griseolinsaeurederivate, ihre herstellung und ihre verwendung. |
Country Status (2)
| Country | Link |
|---|---|
| EP (2) | EP0319050B1 (de) |
| AT (1) | ATE48611T1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3919192A (en) * | 1972-05-22 | 1975-11-11 | Icn Pharmaceuticals | 5-Amino-4-substituted imidazole nucleotides |
| US4167565A (en) * | 1976-11-08 | 1979-09-11 | Abbott Laboratories | Adenosine-5'-carboxamides and method of use |
| JPS5668695A (en) | 1979-11-10 | 1981-06-09 | Sankyo Co Ltd | Enzyme inhibitor griseolic acid and its preparation |
| JPS6094992A (ja) * | 1983-10-28 | 1985-05-28 | Sankyo Co Ltd | グリゼオ−ル酸誘導体 |
| JPS60246396A (ja) | 1984-05-22 | 1985-12-06 | Sankyo Co Ltd | 酵素阻害物質ジヒドロデスオキシグリゼオ−ル酸及びその塩類 |
-
1986
- 1986-04-21 EP EP88121486A patent/EP0319050B1/de not_active Expired - Lifetime
- 1986-04-21 EP EP88121487A patent/EP0318060B1/de not_active Expired - Lifetime
- 1986-04-21 AT AT86303000T patent/ATE48611T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0318060B1 (de) | 1995-10-25 |
| EP0318060A3 (en) | 1990-10-24 |
| EP0319050B1 (de) | 1995-04-12 |
| EP0318060A2 (de) | 1989-05-31 |
| EP0319050A2 (de) | 1989-06-07 |
| EP0319050A3 (en) | 1990-10-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |