CY1108963T1 - Λιπαρα οξεα μεσης-αλυσου, γλυκεριδια και αναλογα ως διεγερτες ερυθροποιησης - Google Patents
Λιπαρα οξεα μεσης-αλυσου, γλυκεριδια και αναλογα ως διεγερτες ερυθροποιησηςInfo
- Publication number
- CY1108963T1 CY1108963T1 CY20091100397T CY091100397T CY1108963T1 CY 1108963 T1 CY1108963 T1 CY 1108963T1 CY 20091100397 T CY20091100397 T CY 20091100397T CY 091100397 T CY091100397 T CY 091100397T CY 1108963 T1 CY1108963 T1 CY 1108963T1
- Authority
- CY
- Cyprus
- Prior art keywords
- glycerides
- analogs
- oil fat
- chain oil
- fat acids
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 101000987586 Homo sapiens Eosinophil peroxidase Proteins 0.000 abstract 1
- 101000920686 Homo sapiens Erythropoietin Proteins 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000010437 erythropoiesis Effects 0.000 abstract 1
- 102000044890 human EPO Human genes 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44545403P | 2003-02-07 | 2003-02-07 | |
| EP04708802A EP1592416B1 (en) | 2003-02-07 | 2004-02-06 | Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108963T1 true CY1108963T1 (el) | 2014-07-02 |
Family
ID=32850990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091100397T CY1108963T1 (el) | 2003-02-07 | 2009-04-06 | Λιπαρα οξεα μεσης-αλυσου, γλυκεριδια και αναλογα ως διεγερτες ερυθροποιησης |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US9682054B2 (enExample) |
| EP (1) | EP1592416B1 (enExample) |
| JP (1) | JP5390070B2 (enExample) |
| KR (1) | KR101120775B1 (enExample) |
| CN (1) | CN100427081C (enExample) |
| AP (1) | AP2005003367A0 (enExample) |
| AR (1) | AR043120A1 (enExample) |
| AT (1) | ATE419846T1 (enExample) |
| AU (1) | AU2004210193B2 (enExample) |
| BR (1) | BRPI0407276A (enExample) |
| CA (1) | CA2515160C (enExample) |
| CY (1) | CY1108963T1 (enExample) |
| DE (2) | DE04708802T1 (enExample) |
| DK (1) | DK1592416T3 (enExample) |
| EA (1) | EA009939B1 (enExample) |
| ES (1) | ES2255467T3 (enExample) |
| IL (1) | IL170057A (enExample) |
| JO (1) | JO2705B1 (enExample) |
| MA (1) | MA27664A1 (enExample) |
| MX (1) | MXPA05008382A (enExample) |
| MY (1) | MY140913A (enExample) |
| NO (1) | NO334085B1 (enExample) |
| NZ (1) | NZ541593A (enExample) |
| PT (1) | PT1592416E (enExample) |
| SI (1) | SI1592416T1 (enExample) |
| TN (1) | TNSN05189A1 (enExample) |
| WO (1) | WO2004069237A1 (enExample) |
| ZA (1) | ZA200506246B (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2444463C (en) | 2001-04-18 | 2012-03-20 | Prometic Biosciences Inc. | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
| US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| US20050232981A1 (en) * | 2004-04-15 | 2005-10-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| ES2551852T3 (es) | 2004-07-23 | 2015-11-24 | Acceleron Pharma Inc. | Polipéptidos del receptor ActRII |
| CA2578993A1 (en) * | 2004-09-03 | 2006-03-09 | Prometic Biosciences Inc. | Substituted purinyl derivatives with immunomodulator and chemoprotective activity and use alone or with medium-chain length fatty acids or glycerides |
| NZ554176A (en) | 2004-10-01 | 2010-04-30 | Prometic Biosciences Inc | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
| US8071580B2 (en) | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| EA201692543A1 (ru) | 2005-11-23 | 2017-08-31 | Акселерон Фарма Инк. | Антагонисты активина-actriia и их применение для стимулирования роста кости |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| CA2677007A1 (en) | 2007-02-01 | 2008-08-07 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for treating or preventing breast cancer |
| TWI782836B (zh) | 2007-02-02 | 2022-11-01 | 美商艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
| CA3039330C (en) | 2007-02-09 | 2021-11-09 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for promoting bone growth in cancer patients |
| CN103877564A (zh) | 2007-09-18 | 2014-06-25 | 阿塞勒隆制药公司 | 活化素-actriia拮抗剂和减少或抑制fsh分泌的用途 |
| PT2299998T (pt) | 2007-11-02 | 2018-04-02 | Prometic Pharma Smt Ltd | Acidos gordos e glicerídeos de cadeia média como agentes nefroprotetores |
| EP2231166B1 (en) * | 2007-12-19 | 2013-03-20 | ProMetic BioSciences Inc. | Medium-chain length fatty acids, salts and triglycerides in combination with gemcitabine for treatment of pancreatic cancer |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| JP5922928B2 (ja) | 2008-08-14 | 2016-05-24 | アクセルロン ファーマ, インコーポレイテッド | 赤血球レベルを高めるためのgdfトラップの使用 |
| HRP20170929T1 (hr) | 2008-09-17 | 2017-09-22 | Chiasma Inc. | Farmaceutski pripravci i odgovarajući postupci za isporuku |
| CN102482339B (zh) | 2009-06-08 | 2015-06-17 | 阿塞勒隆制药公司 | 用于增加产热脂肪细胞的方法 |
| EP2440577A4 (en) | 2009-06-12 | 2013-01-23 | Acceleron Pharma Inc | SHORTEN ACTRIIB FC FUSION PROTEINS |
| ES2796121T3 (es) * | 2009-08-13 | 2020-11-25 | Acceleron Pharma Inc | Uso combinado de trampas de GDF y activadores del receptor de la eritropoyetina para aumentar los niveles de glóbulos rojos |
| ES2658292T3 (es) | 2009-11-17 | 2018-03-09 | Acceleron Pharma, Inc. | Proteínas ActRIIB y variantes y usos de las mismas con respecto a la inducción de la utrofina para el tratamiento de la distrofia muscular |
| CN103298832A (zh) | 2010-11-08 | 2013-09-11 | 阿塞勒隆制药公司 | Actriia结合剂及其用途 |
| TWI572352B (zh) * | 2012-03-01 | 2017-03-01 | 波麥堤克藥學Smt有限公司 | 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法 |
| MX366336B (es) | 2012-11-02 | 2019-07-05 | Celgene Corp | Antagonistas de activina - actrii y usos para el tratar trastornos oseos y otros. |
| CN102973922B (zh) * | 2012-12-18 | 2016-02-03 | 华东理工大学 | 一种融合蛋白的应用 |
| AU2015274277B2 (en) | 2014-06-13 | 2021-03-18 | Acceleron Pharma, Inc. | Methods and compositions for treating ulcers |
| MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
| SMT202300166T1 (it) | 2014-12-03 | 2023-07-20 | Celgene Corp | Antagonisti di attivina- actrii e usi per il trattamento di sindrome mielodisplastica |
| AU2016215350B2 (en) | 2015-02-03 | 2021-11-25 | Amryt Endo, Inc. | Method of treating diseases |
| US20170021029A1 (en) * | 2015-04-15 | 2017-01-26 | Jeffrey Charles Raber | Topical formulations and uses |
| CA3112073A1 (en) | 2018-10-11 | 2020-04-16 | Basf As | Aromatic compounds and pharmaceutical uses thereof |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
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| US4871768A (en) * | 1984-07-12 | 1989-10-03 | New England Deaconess Hospital Corporation | Dietary supplement utilizing ω-3/medium chain trigylceride mixtures |
| US7307166B1 (en) * | 1987-10-28 | 2007-12-11 | Wellstat Therapeutics Corporation | Oxpurine nucleosides and their congeners, and acyl, derivatives thereof, for improvement of hematopoiesis |
| US5011852A (en) * | 1988-07-25 | 1991-04-30 | Applied Analytical Industries, Inc. | Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs |
| JP3014119B2 (ja) * | 1990-05-28 | 2000-02-28 | 雪印乳業株式会社 | 直腸投与用赤血球造血剤 |
| JP3249147B2 (ja) | 1990-06-01 | 2002-01-21 | キリン−アムジエン・インコーポレーテツド | 生理活性蛋白含有経口製剤 |
| EP0495187B1 (en) * | 1991-01-15 | 1997-01-22 | Hemosphere, Inc. | Protein nanomatrixes and method of production |
| JPH05163160A (ja) * | 1991-12-13 | 1993-06-29 | Snow Brand Milk Prod Co Ltd | 免疫低下に伴う感染症の予防及び治療用栄養剤 |
| US5214035A (en) * | 1992-04-16 | 1993-05-25 | Hoechst-Roussel Agri-Vet Company | Thixotropic formulations |
| US5318781A (en) * | 1993-04-06 | 1994-06-07 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
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| AU7082694A (en) * | 1994-05-10 | 1995-11-29 | Kitasato Institute, The | Hematopoietic stem cell proliferation accelerator |
| US5470861A (en) * | 1994-08-04 | 1995-11-28 | Hoffmann-La Roche Inc. | Method of promoting hair growth |
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| JPH08208510A (ja) | 1994-11-03 | 1996-08-13 | F Hoffmann La Roche Ag | インターフェロン組成物 |
| GB9516268D0 (en) | 1995-08-08 | 1995-10-11 | Danbiosyst Uk | Compositiion for enhanced uptake of polar drugs from the colon |
| AUPN933396A0 (en) * | 1996-04-17 | 1996-05-09 | Pfizer Pty Limited | Non-aqueuos oral-drench compositions containing avermectin compounds |
| US5851534A (en) | 1996-05-03 | 1998-12-22 | Dynagen, Inc. | Methods for prevention and/or treatment of neutropenia |
| JPH10265380A (ja) | 1997-03-17 | 1998-10-06 | Bristol Myers Squibb Co | 抗ガン剤 |
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| ATE554748T1 (de) * | 1997-11-14 | 2012-05-15 | Pacira Pharmaceuticals Inc | Herstellung von multivesikulären liposomen |
| WO1999025312A1 (en) * | 1997-11-19 | 1999-05-27 | Hercules Incorporated | Fluidized polymer suspensions of cationic polysaccharides in emollients and use thereof in preparing personal care compositions |
| EP1061932B1 (en) * | 1997-11-20 | 2006-01-25 | Gil Ja Jhon | Pharmaceutical composition containing extracts of cervus nippon antlers having growth-stimulating activities of hematopoietic stem cells and megakaryocytes |
| DE69825137T2 (de) * | 1998-02-23 | 2005-07-21 | Cilag Ag International | Liposomale Erythropoietin-Dispersion |
| KR20010041696A (ko) * | 1998-03-11 | 2001-05-25 | 그레랑 파마수티컬 가부시키가이샤 | 발포성 장용(腸溶) 제제 |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| WO2001022937A1 (en) * | 1999-09-27 | 2001-04-05 | Sonus Pharmaceuticals, Inc. | Compositions of tocol-soluble therapeutics |
| US6835750B1 (en) * | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
| ATE341331T1 (de) | 2000-06-14 | 2006-10-15 | William Leslie Porter | Lipide zur änderung des abwehrsystems |
| US6967028B2 (en) | 2000-07-31 | 2005-11-22 | Mainelab | Prolonged release microspheres for injectable administration |
| IL142535A0 (en) | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of inflammation |
| CA2444463C (en) * | 2001-04-18 | 2012-03-20 | Prometic Biosciences Inc. | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
| US20040052836A1 (en) * | 2002-09-13 | 2004-03-18 | Li Luk Chiu | Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life |
| US6725510B1 (en) * | 2003-04-25 | 2004-04-27 | Almetta Clyburn | Inclining coffin |
| DE602004006137T3 (de) | 2003-07-25 | 2012-01-19 | Prometic Biosciences Inc. | Herstellung von metallsalzen von fettsäuren mit mittlerer kettenlänge |
| CA2578993A1 (en) * | 2004-09-03 | 2006-03-09 | Prometic Biosciences Inc. | Substituted purinyl derivatives with immunomodulator and chemoprotective activity and use alone or with medium-chain length fatty acids or glycerides |
| US8071580B2 (en) | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
-
2004
- 2004-02-06 DE DE04708802T patent/DE04708802T1/de active Pending
- 2004-02-06 DK DK04708802T patent/DK1592416T3/da active
- 2004-02-06 MX MXPA05008382A patent/MXPA05008382A/es active IP Right Grant
- 2004-02-06 PT PT04708802T patent/PT1592416E/pt unknown
- 2004-02-06 KR KR1020057014499A patent/KR101120775B1/ko not_active Expired - Fee Related
- 2004-02-06 AP AP2005003367A patent/AP2005003367A0/xx unknown
- 2004-02-06 EP EP04708802A patent/EP1592416B1/en not_active Expired - Lifetime
- 2004-02-06 NZ NZ541593A patent/NZ541593A/xx not_active IP Right Cessation
- 2004-02-06 AT AT04708802T patent/ATE419846T1/de active
- 2004-02-06 BR BR0407276-6A patent/BRPI0407276A/pt not_active Application Discontinuation
- 2004-02-06 AR ARP040100385A patent/AR043120A1/es not_active Application Discontinuation
- 2004-02-06 CA CA2515160A patent/CA2515160C/en not_active Expired - Fee Related
- 2004-02-06 WO PCT/GB2004/000457 patent/WO2004069237A1/en not_active Ceased
- 2004-02-06 ES ES04708802T patent/ES2255467T3/es not_active Expired - Lifetime
- 2004-02-06 ZA ZA200506246A patent/ZA200506246B/en unknown
- 2004-02-06 CN CNB200480004978XA patent/CN100427081C/zh not_active Expired - Fee Related
- 2004-02-06 AU AU2004210193A patent/AU2004210193B2/en not_active Ceased
- 2004-02-06 SI SI200431064T patent/SI1592416T1/sl unknown
- 2004-02-06 DE DE602004018902T patent/DE602004018902D1/de not_active Expired - Lifetime
- 2004-02-06 US US10/544,350 patent/US9682054B2/en not_active Expired - Fee Related
- 2004-02-06 JP JP2006502243A patent/JP5390070B2/ja not_active Expired - Fee Related
- 2004-02-06 EA EA200501267A patent/EA009939B1/ru not_active IP Right Cessation
- 2004-02-07 MY MYPI20040371A patent/MY140913A/en unknown
- 2004-02-24 JO JOP/2004/0017A patent/JO2705B1/ar active
-
2005
- 2005-08-03 TN TNP2005000189A patent/TNSN05189A1/en unknown
- 2005-08-03 IL IL170057A patent/IL170057A/en active IP Right Grant
- 2005-08-26 NO NO20053994A patent/NO334085B1/no not_active IP Right Cessation
- 2005-09-05 MA MA28479A patent/MA27664A1/fr unknown
-
2009
- 2009-04-06 CY CY20091100397T patent/CY1108963T1/el unknown
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