JP2006511495A5 - - Google Patents
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- Publication number
- JP2006511495A5 JP2006511495A5 JP2004548497A JP2004548497A JP2006511495A5 JP 2006511495 A5 JP2006511495 A5 JP 2006511495A5 JP 2004548497 A JP2004548497 A JP 2004548497A JP 2004548497 A JP2004548497 A JP 2004548497A JP 2006511495 A5 JP2006511495 A5 JP 2006511495A5
- Authority
- JP
- Japan
- Prior art keywords
- heterocycle
- aryl
- alkyl
- pharmaceutical composition
- occurrence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42110402P | 2002-10-24 | 2002-10-24 | |
| US10/693,793 US20040087642A1 (en) | 2002-10-24 | 2003-10-23 | Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain |
| PCT/US2003/034006 WO2004039325A2 (en) | 2002-10-24 | 2003-10-24 | Treatment of pain with jnk inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006511495A JP2006511495A (ja) | 2006-04-06 |
| JP2006511495A5 true JP2006511495A5 (https=) | 2006-11-24 |
Family
ID=32179841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004548497A Pending JP2006511495A (ja) | 2002-10-24 | 2003-10-24 | 疼痛の治療、予防、管理および/または改善のためのjnk阻害剤の使用方法およびそれを含む組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20040087642A1 (https=) |
| EP (1) | EP1553951A4 (https=) |
| JP (1) | JP2006511495A (https=) |
| KR (1) | KR20050057673A (https=) |
| AU (1) | AU2003284980B2 (https=) |
| BR (1) | BR0315573A (https=) |
| CA (1) | CA2503616A1 (https=) |
| MX (1) | MXPA05004180A (https=) |
| NZ (1) | NZ540027A (https=) |
| TW (1) | TW200418460A (https=) |
| WO (1) | WO2004039325A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6984652B2 (en) | 2003-09-05 | 2006-01-10 | Warner-Lambert Company Llc | Gyrase inhibitors |
| AU2004283716A1 (en) * | 2003-10-24 | 2005-05-06 | Celgene Corporation | Methods and compositions comprising thalidomide for treatment of fibromyalgia |
| US20050100529A1 (en) * | 2003-11-06 | 2005-05-12 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders |
| ZA200704889B (en) * | 2004-11-23 | 2008-09-25 | Celgene Corp | JNK inhibitors for treatment of CNS injury |
| US20060269579A1 (en) * | 2005-05-25 | 2006-11-30 | Musculoskeletal Research Llc | Compositions for treating osteoarthritis |
| US7767710B2 (en) | 2005-05-25 | 2010-08-03 | Calosyn Pharma, Inc. | Method for treating osteoarthritis |
| WO2008024776A1 (en) * | 2006-08-22 | 2008-02-28 | Children's Medical Center Corporation | Inhibiting jnk signaling promotes cns axon regeneration |
| MX2009006313A (es) * | 2006-12-13 | 2009-06-23 | Organon Nv | Antagonistas v3 para el tratamiento o prevencion de dolor cronico. |
| US8648069B2 (en) | 2007-06-08 | 2014-02-11 | Abbvie Inc. | 5-substituted indazoles as kinase inhibitors |
| MX2009013213A (es) * | 2007-06-08 | 2010-03-30 | Abbott Lab | Indazoles 5-sustituidos 5-heteroarilo como inhibidores de cinasa. |
| EP2184987A4 (en) * | 2007-07-31 | 2011-09-28 | Burnham Inst Medical Research | BIDENTATE COMPOUNDS AS KINASEHEMMER |
| US8372431B2 (en) | 2007-10-26 | 2013-02-12 | Bial-Portela & C.A., S.A. | Pharmaceutical composition comprising licarbazepine acetate |
| US8124764B2 (en) | 2008-07-14 | 2012-02-28 | Gilead Sciences, Inc. | Fused heterocyclyc inhibitor compounds |
| WO2010009166A1 (en) | 2008-07-14 | 2010-01-21 | Gilead Colorado, Inc. | Oxindolyl inhibitor compounds |
| CA2729909A1 (en) | 2008-07-14 | 2010-01-21 | Gilead Sciences, Inc. | Imidazolyl pyrimidine inhibitor compounds |
| CN102123987A (zh) | 2008-07-28 | 2011-07-13 | 吉里德科学公司 | 亚环烷基和亚杂环烷基组蛋白脱乙酰酶抑制剂化合物 |
| US20100056609A1 (en) * | 2008-08-26 | 2010-03-04 | Washington University | Methods and compositions for inhibition of axonal degeneration by modulation of the dlk/jnk pathway |
| KR20120031170A (ko) | 2009-06-08 | 2012-03-30 | 길리애드 사이언시즈, 인코포레이티드 | 알카노일아미노 벤즈아미드 아닐린 hdac 저해제 화합물 |
| US8283357B2 (en) | 2009-06-08 | 2012-10-09 | Gilead Sciences, Inc. | Cycloalkylcarbamate benzamide aniline HDAC inhibitor compounds |
| WO2011160653A1 (en) * | 2010-06-21 | 2011-12-29 | Xigen S.A. | Novel jnk inhibitor molecules |
| BR112013015460B1 (pt) * | 2010-12-20 | 2022-01-25 | Merck Serono S.A. | Derivados de indazolil triazol, kit, e composição farmacêutica |
| WO2012178022A2 (en) * | 2011-06-24 | 2012-12-27 | University Of Massachusetts | Therapeutic applications targeting sarm1 |
| WO2021067749A2 (en) * | 2019-10-02 | 2021-04-08 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for the treatment of osteoarthritis |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3095415A (en) * | 1958-05-30 | 1963-06-25 | Ciba Ltd | Anthraquinone dyestuffs containing a 2-chloro, 4-hydroxy (lower) alkylamino, triazinylamino group |
| CH428043A (fr) * | 1965-08-16 | 1967-01-15 | Sandoz Ag | Procédé de fabrication de colorants de dispersion isothiazolantroniques |
| US3541110A (en) * | 1967-01-20 | 1970-11-17 | American Home Prod | Indazole-5-sulfonamides |
| JPS63184364A (ja) * | 1987-01-27 | 1988-07-29 | Toshiba Corp | 半導体装置の製造方法 |
| NZ227841A (en) * | 1988-02-12 | 1991-08-27 | Merck Sharp & Dohme | Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions |
| US5434136A (en) * | 1990-12-14 | 1995-07-18 | Mathias; John R. | Treatment of motility disorders with a GNRH analog |
| MY113463A (en) * | 1994-01-04 | 2002-03-30 | Novo Nordisk As | Novel heterocyclic compounds |
| US5766605A (en) * | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
| CN1137680C (zh) * | 1995-09-19 | 2004-02-11 | 藤泽药品工业株式会社 | 气雾剂组合物 |
| GB9622363D0 (en) * | 1996-10-28 | 1997-01-08 | Celltech Therapeutics Ltd | Chemical compounds |
| AU6870098A (en) * | 1997-03-31 | 1998-10-22 | Du Pont Merck Pharmaceutical Company, The | Indazoles of cyclic ureas useful as hiv protease inhibitors |
| US6258819B1 (en) * | 1999-08-05 | 2001-07-10 | Syntex (U.S.A.) Llc | Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones |
| BR0013551A (pt) * | 1999-08-13 | 2003-06-17 | Vertex Pharma | Inibidores de cinases n-terminal cjun (jnk) e outras cinases de proteìnas |
| KR20080028516A (ko) * | 1999-08-19 | 2008-03-31 | 시그널 파머슈티컬스 인크 | Jnk억제제로서의 피라졸로안트론과 그 유도체 및 이를함유하는 조성물 |
| YU54202A (sh) * | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
| AU7349301A (en) * | 2000-07-21 | 2002-02-05 | Ortho Mcneil Pharm Inc | Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain |
| US6897231B2 (en) * | 2000-07-31 | 2005-05-24 | Signal Pharmaceuticals, Inc. | Indazole derivatives as JNK inhibitors and compositions and methods related thereto |
| AU8676301A (en) * | 2000-08-25 | 2002-03-04 | Res Corp Technologies Inc | New uses for amino acid anticonvulsants |
| US7129242B2 (en) * | 2000-12-06 | 2006-10-31 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto |
| US6987184B2 (en) * | 2001-02-15 | 2006-01-17 | Signal Pharmaceuticals, Llc | Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related |
| WO2002083083A2 (en) * | 2001-03-30 | 2002-10-24 | King Pharmaceuticals, Inc. | Pharmaceutically active compounds and methods of use |
| GB0108770D0 (en) * | 2001-04-06 | 2001-05-30 | Eisai London Res Lab Ltd | Inhibitors |
| US6562033B2 (en) * | 2001-04-09 | 2003-05-13 | Baylis Medical Co. | Intradiscal lesioning apparatus |
| CN1300116C (zh) * | 2001-04-16 | 2007-02-14 | 卫材株式会社 | 1h-吲唑化合物 |
| GB0112494D0 (en) * | 2001-05-22 | 2001-07-11 | Arachnova Therapeutics Ltd | New therapeutic use |
| GB0115182D0 (en) * | 2001-06-20 | 2001-08-15 | Glaxo Group Ltd | Medicaments |
| BR0212760A (pt) * | 2001-09-19 | 2004-12-07 | Aventis Pharma Sa | Compostos quìmicos |
| TW200302722A (en) * | 2002-02-13 | 2003-08-16 | Astrazeneca Ab | Therapeutic agents |
| WO2003075917A1 (en) * | 2002-03-08 | 2003-09-18 | Signal Pharmaceuticals, Inc. | Combination therapy for treating, preventing or managing proliferative disorders and cancers |
-
2003
- 2003-10-23 US US10/693,793 patent/US20040087642A1/en not_active Abandoned
- 2003-10-24 JP JP2004548497A patent/JP2006511495A/ja active Pending
- 2003-10-24 MX MXPA05004180A patent/MXPA05004180A/es not_active Application Discontinuation
- 2003-10-24 AU AU2003284980A patent/AU2003284980B2/en not_active Ceased
- 2003-10-24 BR BR0315573-0A patent/BR0315573A/pt not_active IP Right Cessation
- 2003-10-24 TW TW092129557A patent/TW200418460A/zh unknown
- 2003-10-24 EP EP03779300A patent/EP1553951A4/en not_active Withdrawn
- 2003-10-24 CA CA002503616A patent/CA2503616A1/en not_active Abandoned
- 2003-10-24 KR KR1020057007019A patent/KR20050057673A/ko not_active Ceased
- 2003-10-24 WO PCT/US2003/034006 patent/WO2004039325A2/en not_active Ceased
- 2003-10-24 NZ NZ540027A patent/NZ540027A/en unknown
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