JP2006511495A5 - - Google Patents

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Publication number
JP2006511495A5
JP2006511495A5 JP2004548497A JP2004548497A JP2006511495A5 JP 2006511495 A5 JP2006511495 A5 JP 2006511495A5 JP 2004548497 A JP2004548497 A JP 2004548497A JP 2004548497 A JP2004548497 A JP 2004548497A JP 2006511495 A5 JP2006511495 A5 JP 2006511495A5
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JP
Japan
Prior art keywords
heterocycle
aryl
alkyl
pharmaceutical composition
occurrence
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Pending
Application number
JP2004548497A
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English (en)
Japanese (ja)
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JP2006511495A (ja
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Publication date
Priority claimed from US10/693,793 external-priority patent/US20040087642A1/en
Application filed filed Critical
Publication of JP2006511495A publication Critical patent/JP2006511495A/ja
Publication of JP2006511495A5 publication Critical patent/JP2006511495A5/ja
Pending legal-status Critical Current

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JP2004548497A 2002-10-24 2003-10-24 疼痛の治療、予防、管理および／または改善のためのｊｎｋ阻害剤の使用方法およびそれを含む組成物 Pending JP2006511495A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42110402P 2002-10-24 2002-10-24
US10/693,793 US20040087642A1 (en) 2002-10-24 2003-10-23 Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain
PCT/US2003/034006 WO2004039325A2 (en) 2002-10-24 2003-10-24 Treatment of pain with jnk inhibitors

Publications (2)

Publication Number Publication Date
JP2006511495A JP2006511495A (ja) 2006-04-06
JP2006511495A5 true JP2006511495A5 (https=) 2006-11-24

Family

ID=32179841

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004548497A Pending JP2006511495A (ja) 2002-10-24 2003-10-24 疼痛の治療、予防、管理および／または改善のためのｊｎｋ阻害剤の使用方法およびそれを含む組成物

Country Status (11)

Country Link
US (1) US20040087642A1 (https=)
EP (1) EP1553951A4 (https=)
JP (1) JP2006511495A (https=)
KR (1) KR20050057673A (https=)
AU (1) AU2003284980B2 (https=)
BR (1) BR0315573A (https=)
CA (1) CA2503616A1 (https=)
MX (1) MXPA05004180A (https=)
NZ (1) NZ540027A (https=)
TW (1) TW200418460A (https=)
WO (1) WO2004039325A2 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984652B2 (en) * 2003-09-05 2006-01-10 Warner-Lambert Company Llc Gyrase inhibitors
KR20060123183A (ko) * 2003-10-24 2006-12-01 셀진 코포레이션 탈리도미드를 포함하는 섬유근육통 치료용 조성물 및 그방법
US20050100529A1 (en) * 2003-11-06 2005-05-12 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders
ZA200704889B (en) * 2004-11-23 2008-09-25 Celgene Corp JNK inhibitors for treatment of CNS injury
US7767710B2 (en) * 2005-05-25 2010-08-03 Calosyn Pharma, Inc. Method for treating osteoarthritis
US20060269579A1 (en) * 2005-05-25 2006-11-30 Musculoskeletal Research Llc Compositions for treating osteoarthritis
WO2008024776A1 (en) * 2006-08-22 2008-02-28 Children's Medical Center Corporation Inhibiting jnk signaling promotes cns axon regeneration
US20100179176A1 (en) * 2006-12-13 2010-07-15 N.V. Organon V3 antagonists for the treatment or prevention of chronic pain
US8648069B2 (en) 2007-06-08 2014-02-11 Abbvie Inc. 5-substituted indazoles as kinase inhibitors
JP5451602B2 (ja) * 2007-06-08 2014-03-26 アッヴィ・インコーポレイテッド キナーゼ阻害薬としての５−ヘテロアリール置換インダゾール類
CA2695384A1 (en) * 2007-07-31 2009-02-05 Burnham Institute For Medical Research Bi-dentate compounds as kinase inhibitors
US8372431B2 (en) * 2007-10-26 2013-02-12 Bial-Portela & C.A., S.A. Pharmaceutical composition comprising licarbazepine acetate
WO2010009166A1 (en) 2008-07-14 2010-01-21 Gilead Colorado, Inc. Oxindolyl inhibitor compounds
NZ602832A (en) 2008-07-14 2014-04-30 Gilead Sciences Inc Fused heterocyclic hdac inhibitor compounds
JP5640005B2 (ja) 2008-07-14 2014-12-10 ギリアード サイエンシーズ， インコーポレイテッド Ｈｄａｃおよび／またはｃｄｋ阻害剤としてのイミダゾシルピリジン化合物
JP2011529504A (ja) 2008-07-28 2011-12-08 ギリアード サイエンシーズ， インコーポレイテッド シクロアルキリデンヒストン脱アセチル化酵素阻害剤化合物およびヘテロシクロアルキリデンヒストン脱アセチル化酵素阻害剤化合物
US20100056609A1 (en) * 2008-08-26 2010-03-04 Washington University Methods and compositions for inhibition of axonal degeneration by modulation of the dlk/jnk pathway
WO2010144378A2 (en) 2009-06-08 2010-12-16 Gilead Colorado, Inc. Cycloalkylcarbamate benzamide aniline hdac inhibitor compounds
KR20120031170A (ko) 2009-06-08 2012-03-30 길리애드 사이언시즈, 인코포레이티드 알카노일아미노 벤즈아미드 아닐린 ｈｄａｃ 저해제 화합물
WO2011160653A1 (en) * 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
BR112013015460B1 (pt) * 2010-12-20 2022-01-25 Merck Serono S.A. Derivados de indazolil triazol, kit, e composição farmacêutica
US20120328629A1 (en) * 2011-06-24 2012-12-27 University Of Miami Therapeutic Applications Targeting SARM1
WO2021067749A2 (en) * 2019-10-02 2021-04-08 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for the treatment of osteoarthritis

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3095415A (en) * 1958-05-30 1963-06-25 Ciba Ltd Anthraquinone dyestuffs containing a 2-chloro, 4-hydroxy (lower) alkylamino, triazinylamino group
CH428043A (fr) * 1965-08-16 1967-01-15 Sandoz Ag Procédé de fabrication de colorants de dispersion isothiazolantroniques
US3541110A (en) * 1967-01-20 1970-11-17 American Home Prod Indazole-5-sulfonamides
JPS63184364A (ja) * 1987-01-27 1988-07-29 Toshiba Corp 半導体装置の製造方法
NZ227841A (en) * 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
MY113463A (en) * 1994-01-04 2002-03-30 Novo Nordisk As Novel heterocyclic compounds
US5766605A (en) * 1994-04-15 1998-06-16 Mount Sinai School Of Medicine Of The City University Of New York Treatment of autonomic nerve dysfunction with botulinum toxin
DK0851753T3 (da) * 1995-09-19 2004-03-15 Fujisawa Pharmaceutical Co Aerosolpræparater
GB9622363D0 (en) * 1996-10-28 1997-01-08 Celltech Therapeutics Ltd Chemical compounds
EP0973767A1 (en) * 1997-03-31 2000-01-26 Dupont Pharmaceuticals Company Indazoles of cyclic ureas useful as hiv protease inhibitors
US6258819B1 (en) * 1999-08-05 2001-07-10 Syntex (U.S.A.) Llc Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones
MXPA02001565A (es) * 1999-08-13 2005-07-14 Vertex Pharma Inhibidores de cinasas c-jun n-terminal (jnk) y de otras cinasas proteicas.
HK1053107A1 (zh) * 1999-08-19 2003-10-10 Signal Pharmaceuticals, Inc. 作为jnk抗化剂的pyrazoloanthrone及其衍生物和它们的成份
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
ATE267629T1 (de) * 2000-07-21 2004-06-15 Ortho Mcneil Pharm Inc Verwendung von carbamat verbindungen zur vorbeugung oder behandlung von neuropathischen- , cluster- und migräneartigen kopfschmerzen
US6897231B2 (en) * 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
DE60131032T2 (de) * 2000-08-25 2008-08-14 Research Corp. Technologies, Inc., Tucson Verwendung von antikonvulsiven Aminosäure zur Behandlung von Migräne
US7129242B2 (en) * 2000-12-06 2006-10-31 Signal Pharmaceuticals, Llc Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto
US6987184B2 (en) * 2001-02-15 2006-01-17 Signal Pharmaceuticals, Llc Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related
ES2365905T3 (es) * 2001-03-30 2011-10-13 King Pharmaceuticals, Inc. Compuestos de tiofeno condensados y uso de los mismos en el tratamiento del dolor crónico.
GB0108770D0 (en) * 2001-04-06 2001-05-30 Eisai London Res Lab Ltd Inhibitors
US6562033B2 (en) * 2001-04-09 2003-05-13 Baylis Medical Co. Intradiscal lesioning apparatus
CN1300116C (zh) * 2001-04-16 2007-02-14 卫材株式会社 1h－吲唑化合物
GB0112494D0 (en) * 2001-05-22 2001-07-11 Arachnova Therapeutics Ltd New therapeutic use
GB0115182D0 (en) * 2001-06-20 2001-08-15 Glaxo Group Ltd Medicaments
IL160915A0 (en) * 2001-09-19 2004-08-31 Aventis Pharma Sa Indolizines inhibiting kinase proteins
TW200302722A (en) * 2002-02-13 2003-08-16 Astrazeneca Ab Therapeutic agents
AU2003217961B2 (en) * 2002-03-08 2008-02-28 Signal Pharmaceuticals, Llc Combination therapy for treating, preventing or managing proliferative disorders and cancers

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