TW200418460A - Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain - Google Patents
Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain Download PDFInfo
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- TW200418460A TW200418460A TW092129557A TW92129557A TW200418460A TW 200418460 A TW200418460 A TW 200418460A TW 092129557 A TW092129557 A TW 092129557A TW 92129557 A TW92129557 A TW 92129557A TW 200418460 A TW200418460 A TW 200418460A
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- pain
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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Landscapes
- Health & Medical Sciences (AREA)
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- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
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| US6984652B2 (en) * | 2003-09-05 | 2006-01-10 | Warner-Lambert Company Llc | Gyrase inhibitors |
| KR20060123183A (ko) * | 2003-10-24 | 2006-12-01 | 셀진 코포레이션 | 탈리도미드를 포함하는 섬유근육통 치료용 조성물 및 그방법 |
| US20050100529A1 (en) * | 2003-11-06 | 2005-05-12 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders |
| ZA200704889B (en) * | 2004-11-23 | 2008-09-25 | Celgene Corp | JNK inhibitors for treatment of CNS injury |
| US7767710B2 (en) * | 2005-05-25 | 2010-08-03 | Calosyn Pharma, Inc. | Method for treating osteoarthritis |
| US20060269579A1 (en) * | 2005-05-25 | 2006-11-30 | Musculoskeletal Research Llc | Compositions for treating osteoarthritis |
| WO2008024776A1 (en) * | 2006-08-22 | 2008-02-28 | Children's Medical Center Corporation | Inhibiting jnk signaling promotes cns axon regeneration |
| US20100179176A1 (en) * | 2006-12-13 | 2010-07-15 | N.V. Organon | V3 antagonists for the treatment or prevention of chronic pain |
| US8648069B2 (en) | 2007-06-08 | 2014-02-11 | Abbvie Inc. | 5-substituted indazoles as kinase inhibitors |
| JP5451602B2 (ja) * | 2007-06-08 | 2014-03-26 | アッヴィ・インコーポレイテッド | キナーゼ阻害薬としての5−ヘテロアリール置換インダゾール類 |
| CA2695384A1 (en) * | 2007-07-31 | 2009-02-05 | Burnham Institute For Medical Research | Bi-dentate compounds as kinase inhibitors |
| US8372431B2 (en) * | 2007-10-26 | 2013-02-12 | Bial-Portela & C.A., S.A. | Pharmaceutical composition comprising licarbazepine acetate |
| WO2010009166A1 (en) | 2008-07-14 | 2010-01-21 | Gilead Colorado, Inc. | Oxindolyl inhibitor compounds |
| NZ602832A (en) | 2008-07-14 | 2014-04-30 | Gilead Sciences Inc | Fused heterocyclic hdac inhibitor compounds |
| JP5640005B2 (ja) | 2008-07-14 | 2014-12-10 | ギリアード サイエンシーズ, インコーポレイテッド | Hdacおよび/またはcdk阻害剤としてのイミダゾシルピリジン化合物 |
| JP2011529504A (ja) | 2008-07-28 | 2011-12-08 | ギリアード サイエンシーズ, インコーポレイテッド | シクロアルキリデンヒストン脱アセチル化酵素阻害剤化合物およびヘテロシクロアルキリデンヒストン脱アセチル化酵素阻害剤化合物 |
| US20100056609A1 (en) * | 2008-08-26 | 2010-03-04 | Washington University | Methods and compositions for inhibition of axonal degeneration by modulation of the dlk/jnk pathway |
| WO2010144378A2 (en) | 2009-06-08 | 2010-12-16 | Gilead Colorado, Inc. | Cycloalkylcarbamate benzamide aniline hdac inhibitor compounds |
| KR20120031170A (ko) | 2009-06-08 | 2012-03-30 | 길리애드 사이언시즈, 인코포레이티드 | 알카노일아미노 벤즈아미드 아닐린 hdac 저해제 화합물 |
| WO2011160653A1 (en) * | 2010-06-21 | 2011-12-29 | Xigen S.A. | Novel jnk inhibitor molecules |
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| WO2021067749A2 (en) * | 2019-10-02 | 2021-04-08 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for the treatment of osteoarthritis |
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| US6258819B1 (en) * | 1999-08-05 | 2001-07-10 | Syntex (U.S.A.) Llc | Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones |
| MXPA02001565A (es) * | 1999-08-13 | 2005-07-14 | Vertex Pharma | Inhibidores de cinasas c-jun n-terminal (jnk) y de otras cinasas proteicas. |
| HK1053107A1 (zh) * | 1999-08-19 | 2003-10-10 | Signal Pharmaceuticals, Inc. | 作为jnk抗化剂的pyrazoloanthrone及其衍生物和它们的成份 |
| YU54202A (sh) * | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
| ATE267629T1 (de) * | 2000-07-21 | 2004-06-15 | Ortho Mcneil Pharm Inc | Verwendung von carbamat verbindungen zur vorbeugung oder behandlung von neuropathischen- , cluster- und migräneartigen kopfschmerzen |
| US6897231B2 (en) * | 2000-07-31 | 2005-05-24 | Signal Pharmaceuticals, Inc. | Indazole derivatives as JNK inhibitors and compositions and methods related thereto |
| DE60131032T2 (de) * | 2000-08-25 | 2008-08-14 | Research Corp. Technologies, Inc., Tucson | Verwendung von antikonvulsiven Aminosäure zur Behandlung von Migräne |
| US7129242B2 (en) * | 2000-12-06 | 2006-10-31 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto |
| US6987184B2 (en) * | 2001-02-15 | 2006-01-17 | Signal Pharmaceuticals, Llc | Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related |
| ES2365905T3 (es) * | 2001-03-30 | 2011-10-13 | King Pharmaceuticals, Inc. | Compuestos de tiofeno condensados y uso de los mismos en el tratamiento del dolor crónico. |
| GB0108770D0 (en) * | 2001-04-06 | 2001-05-30 | Eisai London Res Lab Ltd | Inhibitors |
| US6562033B2 (en) * | 2001-04-09 | 2003-05-13 | Baylis Medical Co. | Intradiscal lesioning apparatus |
| CN1300116C (zh) * | 2001-04-16 | 2007-02-14 | 卫材株式会社 | 1h-吲唑化合物 |
| GB0112494D0 (en) * | 2001-05-22 | 2001-07-11 | Arachnova Therapeutics Ltd | New therapeutic use |
| GB0115182D0 (en) * | 2001-06-20 | 2001-08-15 | Glaxo Group Ltd | Medicaments |
| IL160915A0 (en) * | 2001-09-19 | 2004-08-31 | Aventis Pharma Sa | Indolizines inhibiting kinase proteins |
| TW200302722A (en) * | 2002-02-13 | 2003-08-16 | Astrazeneca Ab | Therapeutic agents |
| AU2003217961B2 (en) * | 2002-03-08 | 2008-02-28 | Signal Pharmaceuticals, Llc | Combination therapy for treating, preventing or managing proliferative disorders and cancers |
-
2003
- 2003-10-23 US US10/693,793 patent/US20040087642A1/en not_active Abandoned
- 2003-10-24 KR KR1020057007019A patent/KR20050057673A/ko not_active Ceased
- 2003-10-24 NZ NZ540027A patent/NZ540027A/en unknown
- 2003-10-24 MX MXPA05004180A patent/MXPA05004180A/es not_active Application Discontinuation
- 2003-10-24 WO PCT/US2003/034006 patent/WO2004039325A2/en not_active Ceased
- 2003-10-24 EP EP03779300A patent/EP1553951A4/en not_active Withdrawn
- 2003-10-24 TW TW092129557A patent/TW200418460A/zh unknown
- 2003-10-24 CA CA002503616A patent/CA2503616A1/en not_active Abandoned
- 2003-10-24 AU AU2003284980A patent/AU2003284980B2/en not_active Ceased
- 2003-10-24 JP JP2004548497A patent/JP2006511495A/ja active Pending
- 2003-10-24 BR BR0315573-0A patent/BR0315573A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1553951A2 (en) | 2005-07-20 |
| KR20050057673A (ko) | 2005-06-16 |
| US20040087642A1 (en) | 2004-05-06 |
| NZ540027A (en) | 2008-04-30 |
| JP2006511495A (ja) | 2006-04-06 |
| AU2003284980B2 (en) | 2008-08-07 |
| MXPA05004180A (es) | 2005-09-20 |
| EP1553951A4 (en) | 2008-06-11 |
| BR0315573A (pt) | 2005-08-30 |
| WO2004039325A2 (en) | 2004-05-13 |
| WO2004039325A3 (en) | 2004-11-11 |
| CA2503616A1 (en) | 2004-05-13 |
| AU2003284980A1 (en) | 2004-05-25 |
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