BR0315573A - Método para tratar, prevenir, controlar e/ou modificar dor em um paciente e composição farmacêutica - Google Patents

Método para tratar, prevenir, controlar e/ou modificar dor em um paciente e composição farmacêutica

Info

Publication number
BR0315573A
BR0315573A BR0315573-0A BR0315573A BR0315573A BR 0315573 A BR0315573 A BR 0315573A BR 0315573 A BR0315573 A BR 0315573A BR 0315573 A BR0315573 A BR 0315573A
Authority
BR
Brazil
Prior art keywords
patient
treating
preventing
controlling
pharmaceutical composition
Prior art date
Application number
BR0315573-0A
Other languages
English (en)
Inventor
Jerome B Zeldis
Herbert Faleck
Donald C Manning
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of BR0315573A publication Critical patent/BR0315573A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

"MéTODO PARA TRATAR, PREVENIR, CONTROLAR E/OU MODIFICAR DOR EM UM PACIENTE E COMPOSIçãO FARMACêUTICA". A presente invenção refere-se aos métodos para tratar, prevenir, controlar e/ou modificar a dor, compreendendo a administração de uma quantidade efetiva de um Inibidor de JNK a um paciente necessitando da mesma. Modalidades específicas incluem a administração de um Inibidor de JNK, sozinho ou em combinação com um segundo agente ativo e/ou terapia cirúrgica ou física. Composições farmacêuticas, formas de dosagem unitárias individuais, e kits adequados nos métodos da invenção também são descritas.
BR0315573-0A 2002-10-24 2003-10-24 Método para tratar, prevenir, controlar e/ou modificar dor em um paciente e composição farmacêutica BR0315573A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42110402P 2002-10-24 2002-10-24
US10/693,793 US20040087642A1 (en) 2002-10-24 2003-10-23 Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain
PCT/US2003/034006 WO2004039325A2 (en) 2002-10-24 2003-10-24 Treatment of pain with jnk inhibitors

Publications (1)

Publication Number Publication Date
BR0315573A true BR0315573A (pt) 2005-08-30

Family

ID=32179841

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0315573-0A BR0315573A (pt) 2002-10-24 2003-10-24 Método para tratar, prevenir, controlar e/ou modificar dor em um paciente e composição farmacêutica

Country Status (11)

Country Link
US (1) US20040087642A1 (pt)
EP (1) EP1553951A4 (pt)
JP (1) JP2006511495A (pt)
KR (1) KR20050057673A (pt)
AU (1) AU2003284980B2 (pt)
BR (1) BR0315573A (pt)
CA (1) CA2503616A1 (pt)
MX (1) MXPA05004180A (pt)
NZ (1) NZ540027A (pt)
TW (1) TW200418460A (pt)
WO (1) WO2004039325A2 (pt)

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BRPI0518255A2 (pt) * 2004-11-23 2008-11-11 Celgene Corp mÉtodos de tratamento ou prevenÇço de uma lesço do sistema nervoso central, para reduzir ou evitar um efeito adverso, e composiÇço farmacÊutica
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US7767710B2 (en) 2005-05-25 2010-08-03 Calosyn Pharma, Inc. Method for treating osteoarthritis
WO2008024776A1 (en) * 2006-08-22 2008-02-28 Children's Medical Center Corporation Inhibiting jnk signaling promotes cns axon regeneration
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WO2009018490A1 (en) 2007-07-31 2009-02-05 Burnham Institute For Medical Research Bi-dentate compounds as kinase inhibitors
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Also Published As

Publication number Publication date
AU2003284980A1 (en) 2004-05-25
US20040087642A1 (en) 2004-05-06
WO2004039325A3 (en) 2004-11-11
CA2503616A1 (en) 2004-05-13
WO2004039325A2 (en) 2004-05-13
TW200418460A (en) 2004-10-01
EP1553951A2 (en) 2005-07-20
NZ540027A (en) 2008-04-30
MXPA05004180A (es) 2005-09-20
AU2003284980B2 (en) 2008-08-07
JP2006511495A (ja) 2006-04-06
EP1553951A4 (en) 2008-06-11
KR20050057673A (ko) 2005-06-16

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