BR0211855A - Medicamento e método para tratamento e melhoria da qualidade restauradora do sono - Google Patents

Medicamento e método para tratamento e melhoria da qualidade restauradora do sono

Info

Publication number
BR0211855A
BR0211855A BR0211855-6A BR0211855A BR0211855A BR 0211855 A BR0211855 A BR 0211855A BR 0211855 A BR0211855 A BR 0211855A BR 0211855 A BR0211855 A BR 0211855A
Authority
BR
Brazil
Prior art keywords
treating
improving
drug
sleep quality
melatonin
Prior art date
Application number
BR0211855-6A
Other languages
English (en)
Inventor
Nava Zisapel
Original Assignee
Neurin Pharmaceuticals 1991 Lt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11075696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0211855(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurin Pharmaceuticals 1991 Lt filed Critical Neurin Pharmaceuticals 1991 Lt
Publication of BR0211855A publication Critical patent/BR0211855A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

"MEDICAMENTO E MéTODO PARA TRATAMENTO E MELHORIA DA QUALIDADE RESTAURADORA DO SONO". A presente invenção está relacionada a um medicamento, para o tratamento e melhoria da qualidade restauradora do sono, em um paciente acometido por insónia primária, que compreende pelo menos um composto selecionado do grupo composto por melatonina, outros agentes melatonérgicos, agonistas de melatonina e antagonistas de melatonina, numa quantidade eficaz dentro da faixa de 0,0025 a 50 mg, e opcionalmente um ou mais outros agentes terapeuticamente ativos.
BR0211855-6A 2001-08-14 2002-08-12 Medicamento e método para tratamento e melhoria da qualidade restauradora do sono BR0211855A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL144900A IL144900A (en) 2001-08-14 2001-08-14 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
PCT/IL2002/000662 WO2003015690A2 (en) 2001-08-14 2002-08-12 Method for treating primary insomnia

Publications (1)

Publication Number Publication Date
BR0211855A true BR0211855A (pt) 2004-09-21

Family

ID=11075696

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211855-6A BR0211855A (pt) 2001-08-14 2002-08-12 Medicamento e método para tratamento e melhoria da qualidade restauradora do sono

Country Status (35)

Country Link
US (1) US8962024B2 (pt)
EP (2) EP1441702B1 (pt)
JP (1) JP2005501095A (pt)
KR (1) KR20040032917A (pt)
CN (1) CN100453078C (pt)
AR (1) AR034975A1 (pt)
AU (1) AU2002326114C1 (pt)
BR (1) BR0211855A (pt)
CA (1) CA2454699C (pt)
CL (1) CL2002001701A1 (pt)
CR (1) CR7271A (pt)
CY (2) CY1118924T1 (pt)
DK (2) DK1441702T3 (pt)
EA (1) EA200400302A1 (pt)
ES (2) ES2882584T3 (pt)
GT (1) GT200200164A (pt)
HK (1) HK1066161A1 (pt)
HU (1) HU230786B1 (pt)
IL (1) IL144900A (pt)
IS (1) IS3004B (pt)
JO (1) JO3446B1 (pt)
LT (1) LT1441702T (pt)
MX (1) MXPA04001372A (pt)
NO (1) NO334788B2 (pt)
NZ (1) NZ531318A (pt)
PA (1) PA8552301A1 (pt)
PE (1) PE20030331A1 (pt)
PL (1) PL367872A1 (pt)
PT (2) PT1441702T (pt)
RU (1) RU2560840C2 (pt)
SI (1) SI1441702T1 (pt)
UA (1) UA87262C2 (pt)
UY (1) UY27401A1 (pt)
WO (1) WO2003015690A2 (pt)
ZA (1) ZA200402005B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
US20070088079A1 (en) * 2005-09-20 2007-04-19 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for sleep disorder
AR056076A1 (es) * 2005-09-20 2007-09-19 Takeda Pharmaceutical Agente profilactico o terapeutico para el desorden de sueno
CA2651862A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2124907B1 (en) 2007-03-19 2018-05-30 Vita Sciences, Llc Transdermal patch and method for delivery of vitamin b12
US20080248106A1 (en) 2007-04-05 2008-10-09 Marvin Heuer Melatonin-based composition for improved sleep
WO2008122102A1 (en) * 2007-04-05 2008-10-16 Iomedix Development International Srl Melatonin-based composition for improved sleep
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
WO2012103411A2 (en) * 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
AU2016426598C1 (en) 2016-10-31 2024-02-08 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) 1964-03-24 Chioacyl
US2789118A (en) 1956-03-30 1957-04-16 American Cyanamid Co 16-alpha oxy-belta1, 4-pregnadienes
US2990401A (en) 1958-06-18 1961-06-27 American Cyanamid Co 11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
US3048581A (en) 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3749712A (en) 1970-09-25 1973-07-31 Sigma Tau Ind Farmaceuti Triamcinolone acetonide esters and process for their preparation
US3996359A (en) 1972-05-19 1976-12-07 Ab Bofors Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
SE378109B (pt) 1972-05-19 1975-08-18 Bofors Ab
SE378110B (pt) 1972-05-19 1975-08-18 Bofors Ab
JPS6045513A (ja) * 1983-05-18 1985-03-12 モナシユ　ユニバ−シテイ 身体行動および機能の日周期の不調を軽減する薬剤
US4600723A (en) * 1983-05-18 1986-07-15 Monash University Method for minimizing disturbances in circadian rhythms of bodily performance and function
EP0126630B1 (en) * 1983-05-18 1987-09-16 Monash University The use of melatonin for the manufacture of a medicament
US5151446A (en) 1989-09-25 1992-09-29 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
FR2658818B1 (fr) 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5591768A (en) * 1990-12-04 1997-01-07 State Of Oregan, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Methods for treating circadian rhythm phase disturbances
US5707652A (en) 1990-12-04 1998-01-13 State Of Oregon Methods of treating circadian rhythm phase disorders
DE122007000073I1 (de) 1991-05-09 2008-01-31 Neurim Pharma 1991 Melatonin enthaltene Arzneimittel
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico
FR2680507B1 (fr) 1991-08-23 1993-10-08 Adir Cie Nouvelles naphtylethylurees et naphtylethylthiourees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE69303919T2 (de) 1992-04-07 1997-01-30 Neurim Pharma 1991 Verwendung von Melatonin zur Herstellung eines Arzneimittels zur Behandlung der gutartigen Prostatahyperplasie
US5449683A (en) * 1992-10-01 1995-09-12 Massachussetts Institute Of Technology Methods of inducing sleep using melatonin
IL103411A (en) 1992-10-11 1996-11-14 Neurim Pharma 1991 Melatonin Controlled Pharmacy Preparation for the Correction of Melatonin Deficiency or Distortion in Melatonin in Human Plasma
CA2150483C (en) 1992-12-17 1999-09-14 Pfizer Limited Pyrazoles and pyrazolopyrimidines
ES2128544T3 (es) 1992-12-17 1999-05-16 Pfizer Pirrolopirimidinas como antagonistas del crf.
BR9307664A (pt) 1992-12-17 1999-06-29 Pfizer Pirazóis substituídos como antagonistas
TW444018B (en) 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
TW336932B (en) 1992-12-17 1998-07-21 Pfizer Amino-substituted pyrazoles
WO1995003043A1 (en) 1993-07-26 1995-02-02 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Sustained release oral compositions containing melatonin
US5654325A (en) * 1993-11-18 1997-08-05 Eli Lilly And Company Melatonin derivatives for use in treating sleep disorders
US5403851A (en) * 1994-04-05 1995-04-04 Interneuron Pharmaceuticals, Inc. Substituted tryptamines, phenalkylamines and related compounds
US6469044B1 (en) * 1995-02-01 2002-10-22 Neurim Pharmaceuticals (1991) Ltd. Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies
US5688520A (en) * 1995-03-29 1997-11-18 Minnesota Mining And Manufacturing Company Transmucosal delivery of melatonin for prevention of migraine
EP0748627A3 (en) 1995-06-14 1997-05-21 Lilly Co Eli Melatonin agonists for the treatment of benign forms of hyperplasia of the prostate
NO981489L (no) * 1995-10-03 1998-05-22 Interneuron Pharma Blandinger av melatonin og analgetika samt anvendelser derav
CA2260269A1 (en) * 1996-07-17 1998-01-22 Merck & Co., Inc. Alteration of circadian rhythmicity with a tachykinin antagonist
US5776969A (en) 1997-02-27 1998-07-07 Eli Lilly And Company Treatment of sleep disorders
US5826408A (en) * 1997-05-08 1998-10-27 Riverwood International Corporation Rotary flap tucker for a cartoning machine
US6472421B1 (en) * 1998-11-13 2002-10-29 Nymox Corporation Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an HMG CoA reductase inhibitor
DK1272177T3 (da) 2000-01-05 2007-08-06 Neurim Pharma 1991 Fremgangsmåde og formulering til behandling af resistens over for antihypertensiva og forbundne tilstande
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
US6703412B1 (en) * 2002-09-27 2004-03-09 Holly A. Rosenthal Method of treating sleeplessness with melatonin on an acute basis
CN103974741A (zh) 2011-09-27 2014-08-06 Ibis医药股份有限公司 胃内植入装置

Also Published As

Publication number Publication date
DK3103443T3 (da) 2021-08-30
JP2005501095A (ja) 2005-01-13
JO3446B1 (ar) 2020-07-05
ZA200402005B (en) 2005-07-27
WO2003015690B1 (en) 2004-03-11
EP1441702A4 (en) 2007-09-26
EP1441702B1 (en) 2017-05-10
GT200200164A (es) 2003-09-26
SI1441702T1 (sl) 2017-08-31
PE20030331A1 (es) 2003-06-27
PL367872A1 (en) 2005-03-07
DK1441702T3 (en) 2017-06-06
CA2454699A1 (en) 2003-02-27
HU230786B1 (en) 2018-05-02
CN1541092A (zh) 2004-10-27
IL144900A (en) 2013-12-31
CN100453078C (zh) 2009-01-21
PA8552301A1 (es) 2003-06-30
CA2454699C (en) 2012-03-27
RU2011131532A (ru) 2013-03-27
CY1124763T1 (el) 2022-07-22
IS3004B (is) 2018-09-15
PT3103443T (pt) 2021-08-12
AR034975A1 (es) 2004-03-24
US20040248966A1 (en) 2004-12-09
HK1066161A1 (en) 2005-03-18
HUP0401042A3 (en) 2009-07-28
NO334788B1 (no) 2014-05-26
UA87262C2 (uk) 2009-07-10
EP3103443A1 (en) 2016-12-14
AU2002326114A1 (en) 2003-03-03
IL144900A0 (en) 2002-06-30
CL2002001701A1 (es) 2010-06-25
UY27401A1 (es) 2003-02-28
EA200400302A1 (ru) 2004-10-28
MXPA04001372A (es) 2005-06-06
CY1118924T1 (el) 2018-01-10
RU2560840C2 (ru) 2015-08-20
PT1441702T (pt) 2017-06-02
KR20040032917A (ko) 2004-04-17
EP3103443B1 (en) 2021-06-30
WO2003015690A3 (en) 2003-09-25
ES2626591T3 (es) 2017-07-25
IS7136A (is) 2004-01-30
HUP0401042A2 (hu) 2004-08-30
CR7271A (es) 2004-05-17
ES2882584T3 (es) 2021-12-02
WO2003015690A2 (en) 2003-02-27
NO20040087L (no) 2004-02-19
AU2002326114B2 (en) 2007-03-08
AU2002326114C1 (en) 2019-03-21
LT1441702T (lt) 2017-06-12
US8962024B2 (en) 2015-02-24
EP1441702A2 (en) 2004-08-04
NO334788B2 (no) 2014-05-26
NZ531318A (en) 2005-08-26

Similar Documents

Publication Publication Date Title
BR0110420A (pt) Agonistas muscarìnicos
BR0209658A (pt) Derivados de 4-amino-5-fenil-7-1ciclobutil-pirrolo [2,3-d] pirimidina
BR0211781A (pt) Forma de dosagem oral, e, métodos para tratar ou prevenir dor, e para preparar forma de dosagem oral
ES2164040T1 (es) Uso de agonistas del sitio de union de la glicina o de inhibidores de la absorcion de la glicina para el tratamiento de trastornos neuropsiquiatricos.
DE69533112D1 (de) Verwendung von flavolignanen zur herstellung von medikamenten mit antiproliferativer aktivität in gebärmutter,brust,eierstöcken
SE0002754D0 (sv) New pharmaceutical combination formulation and method of treatment with the combination
BR9812134A (pt) Composição farmacêutica para tratamento de dismenorréia e parto prematuro
BRPI0410786A (pt) composição, uso da mesma, e, método de tratamento de um distúrbio de humor em um paciente
CY1118924T1 (el) Μεθοδος για θεραπεια της πρωτοπαθους αϋπνιας
CZ176595A3 (en) The application of anticonvulsive agents for the preparation of medicaments intended for treating parkinson's disease and parkinson's syndromes
BR9912508A (pt) Métodos e composições transdérmicas para alìvio da dor
BRPI0511800A (pt) tratamento com irinotecano (cpt-11) e um inibidor de egfr
BR0315573A (pt) Método para tratar, prevenir, controlar e/ou modificar dor em um paciente e composição farmacêutica
BR9813318A (pt) Processo de tratamento de tumores e degeneração macular em paciente humano ou veterinário, composição farmacêutica para tratamento de tumores e degeneração macular em um paciente humano ou veterinário
BR0201524A (pt) Tratamento de combinação para ansiedade e depressão
TW200501948A (en) Composition for improving cognition and memory
BRPI0406634A (pt) Uso de um anagrelìdeo, anagrelìdeo na forma de base, ou um sal farmaceuticamente aceitável do anagrelìdeo, composição farmacêutica não-oral, e dispositivo médido para administração transdérmica
BR0311903A (pt) Tratamento para depressão e ansiedade pela combinação de um inibidor de pde iv e um agente antidepressivo ou ansiolìtico
BR0307022A (pt) Método de tratamento de um paciente que precisa de analgesia
BR0108261A (pt) Uso de mirtazapina, método de tratamento de um distúrbio do sono em um indivìduo, e, kit para paciente para o tratamento de distúrbios do sono
DE69733169D1 (de) Verwendung von Alpha-1-Adrenorezeptor-Antagonisten zur Herstellung eines Medikaments für die Vorbeugung und die Behandlung von Krebs
KR940013503A (ko) 동맥경화증의 예방 또는 치료용 약제학적 조성물
BR0212167A (pt) Forma de dosagem oral de liberação prolongada, uso da mesma, método para a prevenção e/ou tratamento de distúrbios e perturbações médicas, e, processo para a fabricação de uma forma de dosagem de liberação prolongada
WO2003103675A3 (en) COMBINATION THERAPIES FOR PURINOCEPTOR RELATED DISORDERS
BR0209613A (pt) Composição para tratamento de dor em um mamìfero, e, método para redução ou eliminação de probabilidade de viciamento de um analgésico em um hospedeiro

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 9/20

Ipc: A61K 31/4045 (2011.01), A61K 9/20 (2011.01), A61P

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]