HUP0401042A2 - Primer álmatlanság kezelésére alkalmas gyógyszerkészítmények - Google Patents

Primer álmatlanság kezelésére alkalmas gyógyszerkészítmények

Info

Publication number
HUP0401042A2
HUP0401042A2 HU0401042A HUP0401042A HUP0401042A2 HU P0401042 A2 HUP0401042 A2 HU P0401042A2 HU 0401042 A HU0401042 A HU 0401042A HU P0401042 A HUP0401042 A HU P0401042A HU P0401042 A2 HUP0401042 A2 HU P0401042A2
Authority
HU
Hungary
Prior art keywords
pharmaceutical compositions
primary insomnia
compositions suitable
treating primary
melatonin
Prior art date
Application number
HU0401042A
Other languages
English (en)
Inventor
Nava Zisapel
Original Assignee
Neurim Pharmaceuticals (1991) Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11075696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0401042(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurim Pharmaceuticals (1991) Ltd. filed Critical Neurim Pharmaceuticals (1991) Ltd.
Publication of HUP0401042A2 publication Critical patent/HUP0401042A2/hu
Publication of HUP0401042A3 publication Critical patent/HUP0401042A3/hu
Publication of HU230786B1 publication Critical patent/HU230786B1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

A találmány primer álmatlanság kezelésére és regeneráló alvásminőségjavítására alkalmas gyógyszerkészítményre vonatkozik, amely legalábbegy vegyület, mégpedig melatonin, egyéb melatonerg anyag, melatoninagonista és melatonin antagonista 0,0025 mg és 50 mg közötti hatásosmennyiségét tartalmazza adott esetben egy vagy több egyéb terápiáshatású szerrel és hordozó- és/vagy segédanyaggal összekeverve. Ó
HU0401042A 2001-08-14 2002-08-12 Pharmaceutical compositions suitable for treating primary insomnia HU230786B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL144900A IL144900A (en) 2001-08-14 2001-08-14 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
PCT/IL2002/000662 WO2003015690A2 (en) 2001-08-14 2002-08-12 Method for treating primary insomnia

Publications (3)

Publication Number Publication Date
HUP0401042A2 true HUP0401042A2 (hu) 2004-08-30
HUP0401042A3 HUP0401042A3 (en) 2009-07-28
HU230786B1 HU230786B1 (en) 2018-05-02

Family

ID=11075696

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401042A HU230786B1 (en) 2001-08-14 2002-08-12 Pharmaceutical compositions suitable for treating primary insomnia

Country Status (35)

Country Link
US (1) US8962024B2 (hu)
EP (2) EP1441702B1 (hu)
JP (1) JP2005501095A (hu)
KR (1) KR20040032917A (hu)
CN (1) CN100453078C (hu)
AR (1) AR034975A1 (hu)
AU (1) AU2002326114C1 (hu)
BR (1) BR0211855A (hu)
CA (1) CA2454699C (hu)
CL (1) CL2002001701A1 (hu)
CR (1) CR7271A (hu)
CY (2) CY1118924T1 (hu)
DK (2) DK3103443T3 (hu)
EA (1) EA200400302A1 (hu)
ES (2) ES2626591T3 (hu)
GT (1) GT200200164A (hu)
HK (1) HK1066161A1 (hu)
HU (1) HU230786B1 (hu)
IL (1) IL144900A (hu)
IS (1) IS3004B (hu)
JO (1) JO3446B1 (hu)
LT (1) LT1441702T (hu)
MX (1) MXPA04001372A (hu)
NO (1) NO334788B1 (hu)
NZ (1) NZ531318A (hu)
PA (1) PA8552301A1 (hu)
PE (1) PE20030331A1 (hu)
PL (1) PL367872A1 (hu)
PT (2) PT1441702T (hu)
RU (1) RU2560840C2 (hu)
SI (1) SI1441702T1 (hu)
UA (1) UA87262C2 (hu)
UY (1) UY27401A1 (hu)
WO (1) WO2003015690A2 (hu)
ZA (1) ZA200402005B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
AR056076A1 (es) * 2005-09-20 2007-09-19 Takeda Pharmaceutical Agente profilactico o terapeutico para el desorden de sueno
US20070088079A1 (en) * 2005-09-20 2007-04-19 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for sleep disorder
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
US8940326B2 (en) 2007-03-19 2015-01-27 Vita Sciences Llc Transdermal patch and method for delivery of vitamin B12
US20080248106A1 (en) 2007-04-05 2008-10-09 Marvin Heuer Melatonin-based composition for improved sleep
WO2008122102A1 (en) * 2007-04-05 2008-10-16 Iomedix Development International Srl Melatonin-based composition for improved sleep
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
US8691275B2 (en) * 2011-01-28 2014-04-08 Zx Pharma, Llc Controlled-release melatonin compositions and related methods
HUE051362T2 (hu) 2016-10-31 2021-03-01 Neurim Pharma 1991 Melatonin minitabletták és eljárás azok elõállítására
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same

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US3749712A (en) 1970-09-25 1973-07-31 Sigma Tau Ind Farmaceuti Triamcinolone acetonide esters and process for their preparation
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US3996359A (en) 1972-05-19 1976-12-07 Ab Bofors Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
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JPS6045513A (ja) * 1983-05-18 1985-03-12 モナシユ ユニバ−シテイ 身体行動および機能の日周期の不調を軽減する薬剤
US4600723A (en) * 1983-05-18 1986-07-15 Monash University Method for minimizing disturbances in circadian rhythms of bodily performance and function
EP0126630B1 (en) * 1983-05-18 1987-09-16 Monash University The use of melatonin for the manufacture of a medicament
US5151446A (en) 1989-09-25 1992-09-29 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
FR2658818B1 (fr) 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5707652A (en) 1990-12-04 1998-01-13 State Of Oregon Methods of treating circadian rhythm phase disorders
US5591768A (en) * 1990-12-04 1997-01-07 State Of Oregan, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Methods for treating circadian rhythm phase disturbances
EP0518468B1 (en) 1991-05-09 1999-06-30 Neurim Pharmaceuticals (1991) Limited Melatonin containing compositions
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico
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Also Published As

Publication number Publication date
JO3446B1 (ar) 2020-07-05
ES2626591T3 (es) 2017-07-25
EA200400302A1 (ru) 2004-10-28
LT1441702T (lt) 2017-06-12
AR034975A1 (es) 2004-03-24
WO2003015690A3 (en) 2003-09-25
WO2003015690A2 (en) 2003-02-27
GT200200164A (es) 2003-09-26
KR20040032917A (ko) 2004-04-17
PL367872A1 (en) 2005-03-07
ZA200402005B (en) 2005-07-27
IS7136A (is) 2004-01-30
SI1441702T1 (sl) 2017-08-31
CY1124763T1 (el) 2022-07-22
CY1118924T1 (el) 2018-01-10
MXPA04001372A (es) 2005-06-06
AU2002326114A1 (en) 2003-03-03
DK1441702T3 (en) 2017-06-06
ES2882584T3 (es) 2021-12-02
AU2002326114B2 (en) 2007-03-08
CN1541092A (zh) 2004-10-27
HU230786B1 (en) 2018-05-02
EP1441702B1 (en) 2017-05-10
EP3103443B1 (en) 2021-06-30
NO334788B2 (no) 2014-05-26
PT1441702T (pt) 2017-06-02
US20040248966A1 (en) 2004-12-09
UY27401A1 (es) 2003-02-28
NZ531318A (en) 2005-08-26
CN100453078C (zh) 2009-01-21
CR7271A (es) 2004-05-17
NO334788B1 (no) 2014-05-26
JP2005501095A (ja) 2005-01-13
IS3004B (is) 2018-09-15
UA87262C2 (uk) 2009-07-10
WO2003015690B1 (en) 2004-03-11
BR0211855A (pt) 2004-09-21
EP1441702A4 (en) 2007-09-26
CL2002001701A1 (es) 2010-06-25
CA2454699C (en) 2012-03-27
IL144900A0 (en) 2002-06-30
PT3103443T (pt) 2021-08-12
HUP0401042A3 (en) 2009-07-28
HK1066161A1 (en) 2005-03-18
EP3103443A1 (en) 2016-12-14
CA2454699A1 (en) 2003-02-27
EP1441702A2 (en) 2004-08-04
IL144900A (en) 2013-12-31
PA8552301A1 (es) 2003-06-30
US8962024B2 (en) 2015-02-24
DK3103443T3 (da) 2021-08-30
NO20040087L (no) 2004-02-19
RU2560840C2 (ru) 2015-08-20
PE20030331A1 (es) 2003-06-27
RU2011131532A (ru) 2013-03-27
AU2002326114C1 (en) 2019-03-21

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