CY1118924T1 - Μεθοδος για θεραπεια της πρωτοπαθους αϋπνιας - Google Patents
Μεθοδος για θεραπεια της πρωτοπαθους αϋπνιαςInfo
- Publication number
- CY1118924T1 CY1118924T1 CY20171100561T CY171100561T CY1118924T1 CY 1118924 T1 CY1118924 T1 CY 1118924T1 CY 20171100561 T CY20171100561 T CY 20171100561T CY 171100561 T CY171100561 T CY 171100561T CY 1118924 T1 CY1118924 T1 CY 1118924T1
- Authority
- CY
- Cyprus
- Prior art keywords
- melatonin
- treatment
- autopath
- agents
- medicament
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
Η εφεύρεση αφορά σε ένα φάρμακο, για τη θεραπεία και βελτίωση της αποκαταστιτικής ποιότητας του ύπνου, σε έναν ασθενή που πάσχει από πρωτοπαθή αϋπνία, το οποίο περιλαμβάνει τουλάχιστον ένα συστατικό που επιλέγεται από τη μελατονίνη, άλλους μελατονεργικούς παράγοντες, αγωνιστές της μελατονίνης και ανταγωνιστές της μελατονίνης, σε μια αποτελεσματική ποσότητα μέσα στο εύρος 0,0025 έως 50 mg, και προαιρετικά έναν ή περισσότερους θεραπευτικούς δραστικούς παράγοντες.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL144900A IL144900A (en) | 2001-08-14 | 2001-08-14 | Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs |
PCT/IL2002/000662 WO2003015690A2 (en) | 2001-08-14 | 2002-08-12 | Method for treating primary insomnia |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1118924T1 true CY1118924T1 (el) | 2018-01-10 |
Family
ID=11075696
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20171100561T CY1118924T1 (el) | 2001-08-14 | 2017-05-31 | Μεθοδος για θεραπεια της πρωτοπαθους αϋπνιας |
CY20211100776T CY1124763T1 (el) | 2001-08-14 | 2021-08-31 | Μεθοδος για την θεραπευτικη αντιμετωπιση της πρωτοπαθους αϋπνιας |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20211100776T CY1124763T1 (el) | 2001-08-14 | 2021-08-31 | Μεθοδος για την θεραπευτικη αντιμετωπιση της πρωτοπαθους αϋπνιας |
Country Status (35)
Country | Link |
---|---|
US (1) | US8962024B2 (el) |
EP (2) | EP3103443B1 (el) |
JP (1) | JP2005501095A (el) |
KR (1) | KR20040032917A (el) |
CN (1) | CN100453078C (el) |
AR (1) | AR034975A1 (el) |
AU (1) | AU2002326114C1 (el) |
BR (1) | BR0211855A (el) |
CA (1) | CA2454699C (el) |
CL (1) | CL2002001701A1 (el) |
CR (1) | CR7271A (el) |
CY (2) | CY1118924T1 (el) |
DK (2) | DK3103443T3 (el) |
EA (1) | EA200400302A1 (el) |
ES (2) | ES2626591T3 (el) |
GT (1) | GT200200164A (el) |
HK (1) | HK1066161A1 (el) |
HU (1) | HU230786B1 (el) |
IL (1) | IL144900A (el) |
IS (1) | IS3004B (el) |
JO (1) | JO3446B1 (el) |
LT (1) | LT1441702T (el) |
MX (1) | MXPA04001372A (el) |
NO (1) | NO334788B2 (el) |
NZ (1) | NZ531318A (el) |
PA (1) | PA8552301A1 (el) |
PE (1) | PE20030331A1 (el) |
PL (1) | PL367872A1 (el) |
PT (2) | PT3103443T (el) |
RU (1) | RU2560840C2 (el) |
SI (1) | SI1441702T1 (el) |
UA (1) | UA87262C2 (el) |
UY (1) | UY27401A1 (el) |
WO (1) | WO2003015690A2 (el) |
ZA (1) | ZA200402005B (el) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL144900A (en) | 2001-08-14 | 2013-12-31 | Neurim Pharma 1991 | Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs |
IL149377A (en) * | 2002-04-28 | 2012-10-31 | Neurim Pharma 1991 | Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds |
AR056076A1 (es) * | 2005-09-20 | 2007-09-19 | Takeda Pharmaceutical | Agente profilactico o terapeutico para el desorden de sueno |
US20070088079A1 (en) * | 2005-09-20 | 2007-04-19 | Takeda Pharmaceutical Company Limited | Prophylactic or therapeutic agent for sleep disorder |
JP2009536667A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス,インコーポレイティド | 5ht受容体介在性の神経新生 |
EP2124907B1 (en) | 2007-03-19 | 2018-05-30 | Vita Sciences, Llc | Transdermal patch and method for delivery of vitamin b12 |
US20080248106A1 (en) | 2007-04-05 | 2008-10-09 | Marvin Heuer | Melatonin-based composition for improved sleep |
WO2008122102A1 (en) * | 2007-04-05 | 2008-10-16 | Iomedix Development International Srl | Melatonin-based composition for improved sleep |
WO2012103411A2 (en) * | 2011-01-28 | 2012-08-02 | Zx Pharma, Llc | Controlled-release melatonin composition and related methods |
US9532952B2 (en) | 2011-01-28 | 2017-01-03 | Physician's Seal, LLC | Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients |
US10849856B2 (en) | 2016-10-31 | 2020-12-01 | Neurim Pharmaceuticals Ltd. | Melatonin mini-tablets and method of manufacturing the same |
EP3777842A1 (en) | 2016-10-31 | 2021-02-17 | Neurim Pharmaceuticals Ltd. | Melatonin mini-tablets and method of manufacturing the same |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3126375A (en) | 1964-03-24 | Chioacyl | ||
US2789118A (en) | 1956-03-30 | 1957-04-16 | American Cyanamid Co | 16-alpha oxy-belta1, 4-pregnadienes |
US2990401A (en) | 1958-06-18 | 1961-06-27 | American Cyanamid Co | 11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids |
US3048581A (en) | 1960-04-25 | 1962-08-07 | Olin Mathieson | Acetals and ketals of 16, 17-dihydroxy steroids |
US3749712A (en) | 1970-09-25 | 1973-07-31 | Sigma Tau Ind Farmaceuti | Triamcinolone acetonide esters and process for their preparation |
SE378109B (el) | 1972-05-19 | 1975-08-18 | Bofors Ab | |
US3996359A (en) | 1972-05-19 | 1976-12-07 | Ab Bofors | Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith |
SE378110B (el) | 1972-05-19 | 1975-08-18 | Bofors Ab | |
US4600723A (en) * | 1983-05-18 | 1986-07-15 | Monash University | Method for minimizing disturbances in circadian rhythms of bodily performance and function |
EP0126630B1 (en) | 1983-05-18 | 1987-09-16 | Monash University | The use of melatonin for the manufacture of a medicament |
JPS6045513A (ja) * | 1983-05-18 | 1985-03-12 | モナシユ ユニバ−シテイ | 身体行動および機能の日周期の不調を軽減する薬剤 |
US5151446A (en) | 1989-09-25 | 1992-09-29 | Northwestern University | Substituted 2-amidotetralins as melatonin agonists and antagonists |
FR2658818B1 (fr) | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5707652A (en) | 1990-12-04 | 1998-01-13 | State Of Oregon | Methods of treating circadian rhythm phase disorders |
US5591768A (en) * | 1990-12-04 | 1997-01-07 | State Of Oregan, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | Methods for treating circadian rhythm phase disturbances |
DE69229490T2 (de) * | 1991-05-09 | 2000-02-17 | Neurim Pharma 1991 | Melatonin enthaltende Arzneimittel |
IT1251544B (it) * | 1991-05-13 | 1995-05-17 | Gabriele Biella | Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico |
FR2680507B1 (fr) | 1991-08-23 | 1993-10-08 | Adir Cie | Nouvelles naphtylethylurees et naphtylethylthiourees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
SG41955A1 (en) | 1992-04-07 | 1997-08-15 | Neurim Pharma 1991 | Use of melatonin for the manufacture of a medicament for the treatment of benign prostatic hyperplasia |
US5449683A (en) | 1992-10-01 | 1995-09-12 | Massachussetts Institute Of Technology | Methods of inducing sleep using melatonin |
IL103411A (en) | 1992-10-11 | 1996-11-14 | Neurim Pharma 1991 | Melatonin Controlled Pharmacy Preparation for the Correction of Melatonin Deficiency or Distortion in Melatonin in Human Plasma |
RU2124015C1 (ru) | 1992-12-17 | 1998-12-27 | Пфайзер Инк. | Производные пирроло [2,3-d] пиримидинов, фармацевтическая композиция, пирроло [2,3-d] пиримидины, производные пиррола |
ATE175961T1 (de) | 1992-12-17 | 1999-02-15 | Pfizer | Pyrazole mit crf antagonistischer aktivität |
TW444018B (en) | 1992-12-17 | 2001-07-01 | Pfizer | Pyrazolopyrimidines |
TW336932B (en) | 1992-12-17 | 1998-07-21 | Pfizer | Amino-substituted pyrazoles |
ES2139676T3 (es) | 1992-12-17 | 2000-02-16 | Pfizer | Pirazoles sustituidos como antagonistas del crf. |
WO1995003043A1 (en) | 1993-07-26 | 1995-02-02 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | Sustained release oral compositions containing melatonin |
US5654325A (en) | 1993-11-18 | 1997-08-05 | Eli Lilly And Company | Melatonin derivatives for use in treating sleep disorders |
US5403851A (en) | 1994-04-05 | 1995-04-04 | Interneuron Pharmaceuticals, Inc. | Substituted tryptamines, phenalkylamines and related compounds |
US6469044B1 (en) * | 1995-02-01 | 2002-10-22 | Neurim Pharmaceuticals (1991) Ltd. | Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies |
US5688520A (en) * | 1995-03-29 | 1997-11-18 | Minnesota Mining And Manufacturing Company | Transmucosal delivery of melatonin for prevention of migraine |
EP0748627A3 (en) | 1995-06-14 | 1997-05-21 | Lilly Co Eli | Melatonin agonists for the treatment of benign forms of hyperplasia of the prostate |
NO981489L (no) * | 1995-10-03 | 1998-05-22 | Interneuron Pharma | Blandinger av melatonin og analgetika samt anvendelser derav |
ATE265209T1 (de) * | 1996-07-17 | 2004-05-15 | Merck & Co Inc | Änderung des zirkadischen rhythmus mit nicht- peptidischen neurokinin-1 rezeptor antagonisten |
US5776969A (en) | 1997-02-27 | 1998-07-07 | Eli Lilly And Company | Treatment of sleep disorders |
US5826408A (en) * | 1997-05-08 | 1998-10-27 | Riverwood International Corporation | Rotary flap tucker for a cartoning machine |
US6472421B1 (en) | 1998-11-13 | 2002-10-29 | Nymox Corporation | Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an HMG CoA reductase inhibitor |
BR0016918A (pt) | 2000-01-05 | 2004-03-23 | Neurim Pharma 1991 | Processo e formulação para o tratamento de resistência a anti-hipertensivos e condições relacionadas |
IL144900A (en) | 2001-08-14 | 2013-12-31 | Neurim Pharma 1991 | Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs |
US6703412B1 (en) | 2002-09-27 | 2004-03-09 | Holly A. Rosenthal | Method of treating sleeplessness with melatonin on an acute basis |
CA2850162A1 (en) | 2011-09-27 | 2013-04-04 | IBIS Medical, Inc. | Intragastric implant devices |
-
2001
- 2001-08-14 IL IL144900A patent/IL144900A/en active IP Right Grant
-
2002
- 2002-07-29 UY UY27401A patent/UY27401A1/es not_active Application Discontinuation
- 2002-07-31 CL CL2002001701A patent/CL2002001701A1/es unknown
- 2002-08-05 AR ARP020102964A patent/AR034975A1/es not_active Application Discontinuation
- 2002-08-08 JO JOP/2002/0086A patent/JO3446B1/ar active
- 2002-08-09 PA PA20028552301A patent/PA8552301A1/es unknown
- 2002-08-12 LT LTEP02760523.7T patent/LT1441702T/lt unknown
- 2002-08-12 JP JP2003520451A patent/JP2005501095A/ja active Pending
- 2002-08-12 HU HU0401042A patent/HU230786B1/hu unknown
- 2002-08-12 IS IS7136A patent/IS3004B/is unknown
- 2002-08-12 CN CNB028158326A patent/CN100453078C/zh not_active Ceased
- 2002-08-12 EP EP16172415.8A patent/EP3103443B1/en not_active Expired - Lifetime
- 2002-08-12 AU AU2002326114A patent/AU2002326114C1/en not_active Expired
- 2002-08-12 ES ES02760523.7T patent/ES2626591T3/es not_active Expired - Lifetime
- 2002-08-12 KR KR10-2004-7002245A patent/KR20040032917A/ko active Search and Examination
- 2002-08-12 US US10/486,688 patent/US8962024B2/en active Active
- 2002-08-12 MX MXPA04001372A patent/MXPA04001372A/es unknown
- 2002-08-12 BR BR0211855-6A patent/BR0211855A/pt not_active Application Discontinuation
- 2002-08-12 EA EA200400302A patent/EA200400302A1/ru unknown
- 2002-08-12 PT PT161724158T patent/PT3103443T/pt unknown
- 2002-08-12 PT PT2760523T patent/PT1441702T/pt unknown
- 2002-08-12 DK DK16172415.8T patent/DK3103443T3/da active
- 2002-08-12 CA CA2454699A patent/CA2454699C/en not_active Expired - Lifetime
- 2002-08-12 EP EP02760523.7A patent/EP1441702B1/en not_active Revoked
- 2002-08-12 PL PL02367872A patent/PL367872A1/xx not_active Application Discontinuation
- 2002-08-12 SI SI200231087T patent/SI1441702T1/sl unknown
- 2002-08-12 WO PCT/IL2002/000662 patent/WO2003015690A2/en active Application Filing
- 2002-08-12 NZ NZ531318A patent/NZ531318A/en not_active IP Right Cessation
- 2002-08-12 RU RU2011131532/15A patent/RU2560840C2/ru active
- 2002-08-12 ES ES16172415T patent/ES2882584T3/es not_active Expired - Lifetime
- 2002-08-12 DK DK02760523.7T patent/DK1441702T3/en active
- 2002-08-13 GT GT200200164A patent/GT200200164A/es unknown
- 2002-08-13 PE PE2002000731A patent/PE20030331A1/es not_active Application Discontinuation
- 2002-12-08 UA UA2004031856A patent/UA87262C2/uk unknown
-
2004
- 2004-01-09 NO NO20040087A patent/NO334788B2/no not_active IP Right Cessation
- 2004-03-03 CR CR7271A patent/CR7271A/es unknown
- 2004-03-12 ZA ZA2004/02005A patent/ZA200402005B/en unknown
- 2004-11-15 HK HK04109022.9A patent/HK1066161A1/xx not_active IP Right Cessation
-
2017
- 2017-05-31 CY CY20171100561T patent/CY1118924T1/el unknown
-
2021
- 2021-08-31 CY CY20211100776T patent/CY1124763T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1118924T1 (el) | Μεθοδος για θεραπεια της πρωτοπαθους αϋπνιας | |
CY1120313T1 (el) | Φαρμακευτικη συνθεση για δερματικη χρηση για να θεραπευεται ψωριαση που περιλαμβανει βιταμινη d και κορτικοστεοειδες | |
CY1107586T1 (el) | Θepαπεiα για τη δυσκοιλιoτητα | |
CY1118179T1 (el) | Φαρμακευτικη συνθεση | |
CY1107383T1 (el) | Αναστολεις της φωσφολιπασης α2 του κυτοπλασμικου διαλυματος | |
DE60316779D1 (de) | Thiadiazolylpiperazinderivate geeignet für die behandlung bzw. prävention von schmerzen | |
ATE355374T1 (de) | Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen | |
SE0002754D0 (sv) | New pharmaceutical combination formulation and method of treatment with the combination | |
EA200500782A1 (ru) | Лечение геморрагического шока | |
CY1106645T1 (el) | Παραγωγα 1,2,4 τριαμινοβενζολης χρησιμα για τη θεραπευτικη αντιμετωπιση διαταραχων του κεντρικου νευρικου συστηματος | |
NO990912L (no) | Terapeutiske kombinasjoner av PAR-antagonister og RXR-agonister og bruken derav | |
ATE260650T1 (de) | Orale darreichungsformen zur verabreichung einer fixen kombination von tramadol und diclofenac | |
NO20004419D0 (no) | Ny anvendelse | |
SE9704644D0 (sv) | New use | |
DK0998287T3 (da) | Anvendelse af levobupivacain | |
EA200501666A1 (ru) | Композиция для улучшения познавательной способности и памяти | |
ATE369348T1 (de) | Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in therapie | |
AR032422A1 (es) | Uso de inhibidores de il-18 para el tratamiento y/o prevencion de la enfermedad cardiaca | |
EE200100520A (et) | N-(2-fenüül-4-aminobutüül)-1-naftamiidid neurokiniin-1-retseptori antagonistidena | |
BG105984A (bg) | Използване на озанетант за приготвяне на лекарствени средства полезни за лечение на разстройства на настроението | |
DE60215219D1 (de) | Verwendung von darifenacin zur behandlung des harndrangs | |
DE602004016547D1 (de) | 1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungen | |
EA200401617A1 (ru) | Комбинация nmda-антагониста и ингибиторов ацетилхолинэстеразы для лечения болезни альцгеймера | |
DE69732492D1 (de) | Verwendung von nk-1 rezeptorantagonisten zur behandlung von schweren depressionen, die von angstzuständen begleitet werden | |
EE04951B1 (et) | R-(+)-alfa-(2,3-dimetoksfenl)-1-[2-(4-fluorofenl)etl]-4-piperidiinmetanooli kasutamine unehirete raviks |