JP2006505505A - 化合物 - Google Patents

化合物 Download PDF

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Publication number
JP2006505505A
JP2006505505A JP2004516690A JP2004516690A JP2006505505A JP 2006505505 A JP2006505505 A JP 2006505505A JP 2004516690 A JP2004516690 A JP 2004516690A JP 2004516690 A JP2004516690 A JP 2004516690A JP 2006505505 A JP2006505505 A JP 2006505505A
Authority
JP
Japan
Prior art keywords
alkyl
hydroxy
substituted
alkenyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004516690A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006505505A5 (https=
Inventor
ジェフリー・マイケル・アクステン
ロバート・エイ・デインズ
デイビッド・トーマス・デイビーズ
ティモシー・フランシス・ギャラガー
グレアム・エルジン・ジョーンズ
ウィリアム・ヘンリー・ミラー
ニール・デイビッド・ピアソン
イズレイル・ペンドラク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JP2006505505A publication Critical patent/JP2006505505A/ja
Publication of JP2006505505A5 publication Critical patent/JP2006505505A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2004516690A 2002-06-26 2003-06-25 化合物 Pending JP2006505505A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39171002P 2002-06-26 2002-06-26
PCT/EP2003/006754 WO2004002490A2 (en) 2002-06-26 2003-06-25 Piperidine compounds as antibacterials

Publications (2)

Publication Number Publication Date
JP2006505505A true JP2006505505A (ja) 2006-02-16
JP2006505505A5 JP2006505505A5 (https=) 2006-06-15

Family

ID=30000740

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004516690A Pending JP2006505505A (ja) 2002-06-26 2003-06-25 化合物

Country Status (7)

Country Link
US (1) US7498326B2 (https=)
EP (1) EP1583537A3 (https=)
JP (1) JP2006505505A (https=)
AR (1) AR040336A1 (https=)
AU (1) AU2003238054A1 (https=)
TW (1) TW200409637A (https=)
WO (1) WO2004002490A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
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JP2010513255A (ja) * 2006-12-15 2010-04-30 アストラゼネカ アクチボラグ ２−キノリノン及び２−キノキサリノン誘導体と抗菌剤としてのそれらの使用
JP2010524884A (ja) * 2007-04-20 2010-07-22 グラクソ グループ リミテッド 抗菌剤としての三環式含窒素化合物
JP2012511566A (ja) * 2008-12-12 2012-05-24 アクテリオン ファーマシューティカルズ リミテッド ５−アミノ−２−（１−ヒドロキシ−エチル）−テトラヒドロピラン誘導体

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CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
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CA2694724C (en) * 2007-08-01 2017-09-12 University Health Network Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer
WO2009040659A2 (en) * 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
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