JP2006504761A5 - - Google Patents
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- Publication number
- JP2006504761A5 JP2006504761A5 JP2004547576A JP2004547576A JP2006504761A5 JP 2006504761 A5 JP2006504761 A5 JP 2006504761A5 JP 2004547576 A JP2004547576 A JP 2004547576A JP 2004547576 A JP2004547576 A JP 2004547576A JP 2006504761 A5 JP2006504761 A5 JP 2006504761A5
- Authority
- JP
- Japan
- Prior art keywords
- chloro
- alkyl
- phenyl
- acetamide
- phenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 B*NC(N(*)***NC)=O Chemical compound B*NC(N(*)***NC)=O 0.000 description 7
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10250743A DE10250743A1 (de) | 2002-10-31 | 2002-10-31 | Neue Amid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| PCT/EP2003/011933 WO2004039764A1 (de) | 2002-10-31 | 2003-10-28 | Neue amid-verbindungen mit mch-antagonistischer wirkung und diese verbindungen enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006504761A JP2006504761A (ja) | 2006-02-09 |
| JP2006504761A5 true JP2006504761A5 (enExample) | 2009-10-08 |
Family
ID=32115015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004547576A Pending JP2006504761A (ja) | 2002-10-31 | 2003-10-28 | Ｍｃｈ拮抗活性を有する新規アミド化合物及びこれらの化合物を含む薬物 |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1558567B1 (enExample) |
| JP (1) | JP2006504761A (enExample) |
| KR (1) | KR20050065654A (enExample) |
| CN (1) | CN1708476A (enExample) |
| AR (1) | AR041735A1 (enExample) |
| AT (1) | ATE434601T1 (enExample) |
| AU (1) | AU2003285306A1 (enExample) |
| BR (1) | BR0315797A (enExample) |
| CA (1) | CA2504207C (enExample) |
| CO (1) | CO5570698A2 (enExample) |
| DE (2) | DE10250743A1 (enExample) |
| EA (1) | EA009040B1 (enExample) |
| EC (1) | ECSP055765A (enExample) |
| ES (1) | ES2327329T3 (enExample) |
| HR (1) | HRP20050383A2 (enExample) |
| MX (1) | MXPA05002865A (enExample) |
| NO (1) | NO20050745L (enExample) |
| PE (1) | PE20040785A1 (enExample) |
| PL (1) | PL376256A1 (enExample) |
| RS (1) | RS20050330A (enExample) |
| TW (1) | TW200412936A (enExample) |
| UY (1) | UY28051A1 (enExample) |
| WO (1) | WO2004039764A1 (enExample) |
| ZA (1) | ZA200501164B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7592373B2 (en) | 2003-12-23 | 2009-09-22 | Boehringer Ingelheim International Gmbh | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds |
| FR2866880A1 (fr) * | 2004-02-27 | 2005-09-02 | Oreal | Para-phenylenediamine secondaire n-alkylaminee ortho-et/ou meta-substituee, composition de teinture des fibres keratiniques contenant une telle para-phenylenediamine, procedes mettant en oeuvre cette composition et utilisations |
| US7605176B2 (en) | 2004-03-06 | 2009-10-20 | Boehringer Ingelheim International Gmbh | β-ketoamide compounds with MCH antagonistic activity |
| JP2006076990A (ja) * | 2004-03-12 | 2006-03-23 | Bayer Cropscience Ag | 殺虫性ベンゼンジカルボキサミド類 |
| US7524862B2 (en) | 2004-04-14 | 2009-04-28 | Boehringer Ingelheim International Gmbh | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds |
| DE102004017934A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| BRPI0716579A2 (pt) | 2006-08-25 | 2013-10-08 | Boehringer Ingelheim Int | Derivados de piridona com atividade antagonista ao mch e medicamentos que compreendem estes compostos |
| WO2008069611A1 (en) * | 2006-12-08 | 2008-06-12 | Korea Research Institute Of Chemical Technology | N-phenylamide derivative, process for the preparation thereof, and composition for preventing or treating ischemic diseases comprising same |
| WO2008071646A1 (en) | 2006-12-11 | 2008-06-19 | Boehringer Ingelheim International Gmbh | New pyridazine derivatives with mch antagonistic activity and medicaments comprising these compounds |
| AR073049A1 (es) * | 2008-08-07 | 2010-10-13 | Bayer Cropscience Sa | Derivados fungicidas de oxialquilamida |
| US8410284B2 (en) | 2008-10-22 | 2013-04-02 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| EP2362731B1 (en) | 2008-10-31 | 2016-04-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| US9452980B2 (en) * | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| JP2013520502A (ja) | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| US9079880B2 (en) * | 2010-07-07 | 2015-07-14 | Boehringer Ingelheim International Gmbh | Rho kinase inhibitors |
| EP2583965B1 (en) * | 2010-07-15 | 2017-01-25 | Takeda Pharmaceutical Company Limited | Heterocyclic ring compound |
| SG192941A1 (en) | 2011-02-25 | 2013-09-30 | Merck Sharp & Dohme | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| CA2842364A1 (en) * | 2011-07-29 | 2013-02-07 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| ES2655645T3 (es) | 2011-07-29 | 2018-02-21 | Karyopharm Therapeutics, Inc. | Moduladores de transporte nuclear que contienen hidrazida y usos de los mismos |
| CA2868484A1 (en) | 2012-03-28 | 2013-10-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Salicylic acid derivatives useful as glucocerebrosidase activators |
| PL3404027T3 (pl) | 2012-05-09 | 2020-09-21 | Biogen Ma Inc. | Modulatory transportu jądrowego i ich zastosowania |
| WO2014022528A1 (en) | 2012-08-02 | 2014-02-06 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| JP2016516004A (ja) | 2013-02-22 | 2016-06-02 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | 抗糖尿病二環式化合物 |
| EP2970119B1 (en) | 2013-03-14 | 2021-11-03 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
| WO2014144772A1 (en) | 2013-03-15 | 2014-09-18 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using crm1 inhibitors |
| LT3010892T (lt) | 2013-06-21 | 2019-04-10 | Karyopharm Therapeutics Inc. | 1,2,4-triazolai kaip branduolio transporto moduliatoriai ir jų panaudojimas |
| DK3013796T3 (da) | 2013-06-27 | 2020-03-16 | Lg Chemical Ltd | Biarylderivater som gpr120-agonister |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| DK3180331T3 (da) | 2014-08-15 | 2022-09-12 | Karyopharm Therapeutics Inc | Polymorfer af selinexor |
| CN105439914B (zh) * | 2014-09-17 | 2017-07-11 | 复旦大学 | 4‑氨酰基苯氧乙酰胺类化合物及其药物用途 |
| CA2970011C (en) * | 2014-12-24 | 2021-08-03 | Lg Chem, Ltd. | Biaryl derivative as gpr120 agonist |
| JP6533997B2 (ja) * | 2014-12-26 | 2019-06-26 | 株式会社ヤクルト本社 | Ｚｎｆ１４３阻害活性を有する化合物およびその利用 |
| EP3397633A1 (en) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| MA43530A (fr) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics Inc | Modulateurs de transport nucléaire et leurs utilisations |
| JP6814814B2 (ja) | 2016-03-17 | 2021-01-20 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｔａａｒのアゴニストとしての活性を有する５−エチル−４−メチル−ピラゾール−３−カルボキサミド誘導体 |
| WO2018098472A1 (en) | 2016-11-28 | 2018-05-31 | Karyopharm Therapeutics Inc. | Crm1 inhibitors for treating epilepsy |
| WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| WO2018118670A1 (en) | 2016-12-20 | 2018-06-28 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
| US20220315545A1 (en) | 2019-07-10 | 2022-10-06 | Bayer Aktiengesellschaft | Process of preparing 2-(phenylimino)-1,3-thiazolidin-4-ones |
| US20240174680A1 (en) | 2021-01-29 | 2024-05-30 | Cedilla Therapeutics, Inc. | Cdk2 inhibitors and methods of using the same |
| US12053459B2 (en) | 2021-06-26 | 2024-08-06 | Cedilla Therapeutics, Inc. | CDK2 inhibitors and methods of using the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1100495A4 (en) * | 1998-07-28 | 2002-09-25 | Smithkline Beecham Corp | PROPENAMIDES AS CCR5 MODULATORS |
| US7115750B1 (en) * | 1999-09-20 | 2006-10-03 | Takeda Pharmaceutical Company Limited | Melanin concentrating hormone antagonist |
| JP2004504303A (ja) * | 2000-07-05 | 2004-02-12 | シナプティック・ファーマスーティカル・コーポレーション | 選択的メラニン凝集ホルモン−１（ｍｃｈ１）受容体アンタゴニストおよびその使用 |
| US20030022891A1 (en) * | 2000-12-01 | 2003-01-30 | Anandan Palani | MCH antagonists and their use in the treatment of obesity |
| AR036939A1 (es) * | 2001-10-25 | 2004-10-13 | Schering Corp | Antagonistas de la hormona de concentracion de melanina (mch) composiciones farmaceuticas, un proceso para su elaboracion y el uso de dichos compuestos, solos o en combinacion, para la elaboracion de un medicamento para el tratamiento de obesidad |
-
2002
- 2002-10-31 DE DE10250743A patent/DE10250743A1/de not_active Withdrawn
-
2003
- 2003-10-28 PL PL03376256A patent/PL376256A1/xx not_active Application Discontinuation
- 2003-10-28 DE DE50311640T patent/DE50311640D1/de not_active Expired - Lifetime
- 2003-10-28 EP EP03778292A patent/EP1558567B1/de not_active Expired - Lifetime
- 2003-10-28 CA CA2504207A patent/CA2504207C/en not_active Expired - Lifetime
- 2003-10-28 HR HR20050383A patent/HRP20050383A2/xx not_active Application Discontinuation
- 2003-10-28 AU AU2003285306A patent/AU2003285306A1/en not_active Abandoned
- 2003-10-28 WO PCT/EP2003/011933 patent/WO2004039764A1/de not_active Ceased
- 2003-10-28 CN CNA2003801022366A patent/CN1708476A/zh active Pending
- 2003-10-28 ES ES03778292T patent/ES2327329T3/es not_active Expired - Lifetime
- 2003-10-28 BR BR0315797-0A patent/BR0315797A/pt not_active IP Right Cessation
- 2003-10-28 KR KR1020057007663A patent/KR20050065654A/ko not_active Withdrawn
- 2003-10-28 AT AT03778292T patent/ATE434601T1/de active
- 2003-10-28 RS YUP-2005/0330A patent/RS20050330A/sr unknown
- 2003-10-28 EA EA200500596A patent/EA009040B1/ru not_active IP Right Cessation
- 2003-10-28 JP JP2004547576A patent/JP2006504761A/ja active Pending
- 2003-10-28 MX MXPA05002865A patent/MXPA05002865A/es not_active Application Discontinuation
- 2003-10-29 UY UY28051A patent/UY28051A1/es not_active Application Discontinuation
- 2003-10-29 PE PE2003001094A patent/PE20040785A1/es not_active Application Discontinuation
- 2003-10-30 TW TW092130313A patent/TW200412936A/zh unknown
- 2003-10-31 AR ARP030103995A patent/AR041735A1/es unknown
-
2005
- 2005-02-09 ZA ZA200501164A patent/ZA200501164B/en unknown
- 2005-02-11 NO NO20050745A patent/NO20050745L/no not_active Application Discontinuation
- 2005-04-27 EC EC2005005765A patent/ECSP055765A/es unknown
- 2005-05-26 CO CO05051560A patent/CO5570698A2/es not_active Application Discontinuation
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