|
US20050119251A1
(en)
*
|
2001-12-21 |
2005-06-02 |
Jian-Min Fu |
Nicotinamide derivatives and their use as therapeutic agents
|
|
DE10217006A1
(de)
*
|
2002-04-16 |
2003-11-06 |
Merck Patent Gmbh |
Substituierte Indole
|
|
DE10259244A1
(de)
*
|
2002-12-17 |
2004-07-01 |
Merck Patent Gmbh |
N-(Indolethyl-)cycloamin-Verbindungen
|
|
PL377325A1
(pl)
*
|
2002-12-20 |
2006-01-23 |
Merck Patent Gmbh |
Podstawione benzodioksepiny
|
|
EP1701940B1
(en)
*
|
2003-12-23 |
2008-05-28 |
H.Lundbeck A/S |
2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri
|
|
AR052308A1
(es)
*
|
2004-07-16 |
2007-03-14 |
Lundbeck & Co As H |
Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
|
|
JP5173190B2
(ja)
|
2004-08-25 |
2013-03-27 |
武田薬品工業株式会社 |
腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
|
|
EP2289510A1
(en)
|
2004-09-20 |
2011-03-02 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
|
|
US7767677B2
(en)
|
2004-09-20 |
2010-08-03 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
|
|
CA2580856A1
(en)
*
|
2004-09-20 |
2006-03-30 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
|
|
US7951805B2
(en)
|
2004-09-20 |
2011-05-31 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
|
|
EP2316458A1
(en)
|
2004-09-20 |
2011-05-04 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
|
|
EP1799667B1
(en)
|
2004-09-20 |
2013-03-20 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as therapeutic agents
|
|
EP1804799B1
(en)
|
2004-09-20 |
2013-08-21 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
|
|
CN101083986A
(zh)
*
|
2004-09-20 |
2007-12-05 |
泽农医药公司 |
双环杂环衍生物及其作为硬脂酰CoA去饱和酶(SCD)抑制剂的用途
|
|
TW200630337A
(en)
*
|
2004-10-14 |
2006-09-01 |
Euro Celtique Sa |
Piperidinyl compounds and the use thereof
|
|
ATE472327T1
(de)
*
|
2005-01-07 |
2010-07-15 |
Hoffmann La Roche |
Ä4-(heteroaryl)piperazin-1-ylü-(2,5-substituier e phenyl)methanon-derivate als glycin-transporter 1 (glyt-1) hemmer zur behandlung von neurologischen und neuropsychiatrischen erkrankungen
|
|
DE102005019670A1
(de)
*
|
2005-04-26 |
2006-11-02 |
Merck Patent Gmbh |
Verfahren zur Herstellung von (5-(4-[4-(5-Cyano-3-indolyl)-butyl)-1-piperazinyl)-benzofuran-2-carboxamid
|
|
EP2029138A1
(en)
|
2005-06-03 |
2009-03-04 |
Xenon Pharmaceuticals Inc. |
Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
|
|
TW200800959A
(en)
|
2005-06-10 |
2008-01-01 |
Wyeth Corp |
Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor
|
|
MX2007015772A
(es)
|
2005-06-17 |
2008-02-22 |
Wyeth Corp |
Compuestos utiles como inhibidores de serotonina y agonistas y antagonistas de 5-ht-1a.
|
|
US7629473B2
(en)
*
|
2005-06-17 |
2009-12-08 |
H. Lundbeck A/S |
2-(1H-indolylsulfanyl)-aryl amine derivatives
|
|
AR054393A1
(es)
*
|
2005-06-17 |
2007-06-20 |
Lundbeck & Co As H |
Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos.
|
|
CA2614544C
(en)
*
|
2005-07-13 |
2013-09-10 |
Banyu Pharmaceutical Co., Ltd. |
Heterocycle-substituted benzimidazole derivative
|
|
JP2009523734A
(ja)
*
|
2006-01-13 |
2009-06-25 |
ワイス |
5−ヒドロキシトリプタミン受容体のためのリガンドとしてのスルホニル置換された1h−インドール
|
|
WO2007110449A1
(en)
*
|
2006-03-29 |
2007-10-04 |
Euro-Celtique S.A. |
Benzenesulfonamide compounds and their use
|
|
WO2007118853A1
(en)
*
|
2006-04-13 |
2007-10-25 |
Euro-Celtique S.A. |
Benzenesulfonamide compounds and their use as blockers of calcium channels
|
|
TW200812963A
(en)
*
|
2006-04-13 |
2008-03-16 |
Euro Celtique Sa |
Benzenesulfonamide compounds and the use thereof
|
|
JP5528699B2
(ja)
|
2006-05-16 |
2014-06-25 |
武田薬品工業株式会社 |
縮合複素環化合物およびその用途
|
|
WO2008015516A1
(en)
*
|
2006-07-28 |
2008-02-07 |
Pfizer Products Inc. |
Fused tricyclic heterocycles for the treatment of schizophrenia
|
|
WO2008124118A1
(en)
|
2007-04-09 |
2008-10-16 |
Purdue Pharma L.P. |
Benzenesulfonyl compounds and the use therof
|
|
CA2685029A1
(en)
*
|
2007-04-26 |
2008-11-06 |
Avalon Pharmaceuticals |
Multi-ring compounds and uses thereof
|
|
CN101784533B
(zh)
*
|
2007-08-22 |
2013-08-21 |
艾博特股份有限两合公司 |
4-苄基氨基喹啉、含有它们的药物组合物和它们在治疗中的用途
|
|
WO2009040659A2
(en)
*
|
2007-09-28 |
2009-04-02 |
Purdue Pharma L.P. |
Benzenesulfonamide compounds and the use thereof
|
|
JP5520051B2
(ja)
|
2007-11-15 |
2014-06-11 |
武田薬品工業株式会社 |
縮合ピリジン誘導体およびその用途
|
|
US8536221B2
(en)
|
2008-02-07 |
2013-09-17 |
Abbvie Inc. |
Amide derivatives as positive allosteric modulators and methods of use thereof
|
|
EP2271625B1
(en)
|
2008-04-01 |
2012-09-12 |
Abbott GmbH & Co. KG |
Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
|
|
GB0813142D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
|
GB0813144D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
|
US8686024B2
(en)
|
2009-02-05 |
2014-04-01 |
Kyoto University |
Indoline derivatives
|
|
AR075442A1
(es)
|
2009-02-16 |
2011-03-30 |
Abbott Gmbh & Co Kg |
Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
|
|
TW201038569A
(en)
|
2009-02-16 |
2010-11-01 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
|
|
CA2759187A1
(en)
*
|
2009-04-03 |
2010-10-07 |
Medisyn Technologies, Inc. |
Compositions for treatment of alzheimer's disease
|
|
US8912220B2
(en)
*
|
2009-08-10 |
2014-12-16 |
Galenea Pharmaceuticals |
Compounds and methods of use thereof
|
|
TWI535440B
(zh)
*
|
2009-10-26 |
2016-06-01 |
Lg生命科學有限公司 |
包括吲哚化合物之醫藥組成物
|
|
WO2011071136A1
(ja)
|
2009-12-11 |
2011-06-16 |
アステラス製薬株式会社 |
線維筋痛症治療剤
|
|
EP2539706B1
(en)
*
|
2010-02-24 |
2015-03-04 |
Research Triangle Institute |
Arylpiperazine opioid receptor antagonists
|
|
WO2012014127A1
(en)
|
2010-07-30 |
2012-02-02 |
Ranbaxy Laboratories Limited |
5-lipoxygenase inhibitors
|
|
US8883839B2
(en)
|
2010-08-13 |
2014-11-11 |
Abbott Laboratories |
Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US9051280B2
(en)
|
2010-08-13 |
2015-06-09 |
AbbVie Deutschland GmbH & Co. KG |
Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US8877794B2
(en)
|
2010-08-13 |
2014-11-04 |
Abbott Laboratories |
Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US9045459B2
(en)
|
2010-08-13 |
2015-06-02 |
AbbVie Deutschland GmbH & Co. KG |
Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US8846743B2
(en)
|
2010-08-13 |
2014-09-30 |
Abbott Laboratories |
Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US9309200B2
(en)
|
2011-05-12 |
2016-04-12 |
AbbVie Deutschland GmbH & Co. KG |
Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
PL395470A1
(pl)
|
2011-06-29 |
2013-01-07 |
Adamed Spólka Z Ograniczona Odpowiedzialnoscia |
Sulfonamidowe pochodne amin alicyklicznych do leczenia chorób osrodkowego ukladu nerwowego
|
|
MX2014001457A
(es)
|
2011-08-05 |
2014-08-21 |
Abbvie Deutschland |
Derivados de aminocromano, de aminotiocromano y de amino-1,2,3,4-tetrahidroquinolina composiciones farmaceuticas que los contienen, y su uso en terapia.
|
|
WO2013072520A1
(en)
|
2011-11-18 |
2013-05-23 |
AbbVie Deutschland GmbH & Co. KG |
N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US9365512B2
(en)
|
2012-02-13 |
2016-06-14 |
AbbVie Deutschland GmbH & Co. KG |
Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US9656955B2
(en)
|
2013-03-15 |
2017-05-23 |
Abbvie Inc. |
Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US9650334B2
(en)
|
2013-03-15 |
2017-05-16 |
Abbvie Inc. |
Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
JO3425B1
(ar)
*
|
2013-07-15 |
2019-10-20 |
Novartis Ag |
مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b
|
|
JP2016533375A
(ja)
|
2013-10-17 |
2016-10-27 |
アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー |
アミノテトラリン誘導体およびアミノインダン誘導体、これらを含有する医薬組成物、および治療におけるこれらの使用
|
|
CA2924689A1
(en)
|
2013-10-17 |
2015-04-23 |
AbbVie Deutschland GmbH & Co. KG |
Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US9550754B2
(en)
|
2014-09-11 |
2017-01-24 |
AbbVie Deutschland GmbH & Co. KG |
4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
EP3233077B1
(en)
|
2014-12-19 |
2026-05-06 |
The Broad Institute, Inc. |
Dopamine d2 receptor ligands
|
|
EP3233799B1
(en)
|
2014-12-19 |
2021-05-19 |
The Broad Institute, Inc. |
Dopamine d2 receptor ligands
|
|
EP3242661B1
(en)
|
2015-01-05 |
2019-08-21 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Myc g-quadruplex stabilizing small molecules and their use
|
|
US11285153B2
(en)
|
2017-09-29 |
2022-03-29 |
Sunshine Lake Pharma Co., Ltd. |
Substituted pyrimidine piperazine compound and use thereof
|
|
WO2019131902A1
(ja)
|
2017-12-27 |
2019-07-04 |
武田薬品工業株式会社 |
腹圧性尿失禁および便失禁の治療薬
|
|
CN112851641B
(zh)
*
|
2019-11-28 |
2023-08-15 |
广东东阳光药业股份有限公司 |
嘧啶苯甲酰胺化合物的盐酸盐及其用途
|