|
GB0117396D0
(en)
|
2001-07-17 |
2001-09-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
AR036375A1
(es)
|
2001-08-30 |
2004-09-01 |
Novartis Ag |
Compuestos pirrolo [2,3-d] pirimidina -2- carbonitrilo, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de medicamentos
|
|
SE0201980D0
(sv)
*
|
2002-06-24 |
2002-06-24 |
Astrazeneca Ab |
Novel compounds
|
|
CN102558155A
(zh)
*
|
2003-01-14 |
2012-07-11 |
阿伦纳药品公司 |
作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗
|
|
EP1927594A1
(en)
|
2003-01-14 |
2008-06-04 |
Arena Pharmaceuticals, Inc. |
1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
|
GB0308208D0
(en)
|
2003-04-09 |
2003-05-14 |
Glaxo Group Ltd |
Chemical compounds
|
|
AR045047A1
(es)
|
2003-07-11 |
2005-10-12 |
Arena Pharm Inc |
Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
|
|
TWI335328B
(en)
*
|
2003-07-14 |
2011-01-01 |
Arena Pharm Inc |
Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related hereto
|
|
JPWO2005085210A1
(ja)
*
|
2004-03-10 |
2008-01-17 |
小野薬品工業株式会社 |
ニトリル化合物およびその化合物を有効成分として含有する医薬組成物
|
|
TW200614993A
(en)
|
2004-06-11 |
2006-05-16 |
Akzo Nobel Nv |
4-phenyl-pyrimidine-2-carbonitrile derivatives
|
|
US7326715B2
(en)
|
2005-09-23 |
2008-02-05 |
N.V. Organon |
4-Phenyl-6-substituted-pyrimidine-2-carbonitrile derivatives
|
|
TW200745055A
(en)
*
|
2005-09-23 |
2007-12-16 |
Organon Nv |
4-Phenyl-6-substituted-pyrimidine-2-carbonitrile derivatives
|
|
TW200734338A
(en)
*
|
2006-01-16 |
2007-09-16 |
Organon Nv |
6-Phenyl-1H-imidazo [4,5-c] pyridine-4-carbonitrile derivatives
|
|
US7687515B2
(en)
|
2006-01-17 |
2010-03-30 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
CN101479269A
(zh)
*
|
2006-06-23 |
2009-07-08 |
阿斯利康(瑞典)有限公司 |
蝶啶衍生物及其作为组织蛋白酶抑制剂的用途
|
|
US20080207683A1
(en)
*
|
2007-02-15 |
2008-08-28 |
Darin Allen |
Biaryl-substituted tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20080200454A1
(en)
*
|
2007-02-15 |
2008-08-21 |
Ameriks Michael K |
Carbon-linked tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20090118274A1
(en)
*
|
2007-02-15 |
2009-05-07 |
Darin Allen |
Monocyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20080269241A1
(en)
*
|
2007-02-15 |
2008-10-30 |
Darin Allen |
Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20090099157A1
(en)
*
|
2007-02-15 |
2009-04-16 |
Ameriks Michael K |
Tetrahydro-pyrazolo-pyridine thioether modulators of cathepsin s
|
|
EP1972630A1
(en)
*
|
2007-03-02 |
2008-09-24 |
Glaxo Group Limited |
Purines as cysteine protease inhibitors
|
|
WO2008107368A1
(en)
*
|
2007-03-02 |
2008-09-12 |
Glaxo Group Limited |
Purines as cysteine protease inhibitors
|
|
TW200911803A
(en)
*
|
2007-07-16 |
2009-03-16 |
Organon Nv |
6-phenyl-1H-imidazo [4,5-c] pyridine-4-carbonitrile derivatives
|
|
US7932251B2
(en)
|
2007-07-16 |
2011-04-26 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
WO2009107767A1
(ja)
*
|
2008-02-29 |
2009-09-03 |
大日本住友製薬株式会社 |
H4受容体アンタゴニスト作用を有する新規2環性ピリミジン誘導体
|
|
EP2297153B1
(en)
|
2008-04-21 |
2015-05-27 |
Lexicon Pharmaceuticals, Inc. |
Limk2 inhibitors, compositions comprising them, and methods of their use
|
|
WO2010059418A1
(en)
*
|
2008-11-19 |
2010-05-27 |
The Government Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Services |
Substituted triazine and purine compounds, methods of inhibiting cruzain and rhodesain and methods of treating chagas disease and african trypanosomiasis
|
|
US8026236B2
(en)
|
2009-01-16 |
2011-09-27 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
TW201035094A
(en)
|
2009-01-16 |
2010-10-01 |
Organon Nv |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
GB0917934D0
(en)
|
2009-10-13 |
2009-11-25 |
Syngenta Ltd |
Herbicidal compounds
|
|
US9115126B2
(en)
|
2010-01-15 |
2015-08-25 |
Merck Sharp & Dohme B.V. |
1H-[1,2,3]triazolo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
MX2013003184A
(es)
|
2010-09-22 |
2013-06-07 |
Arena Pharm Inc |
Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo.
|
|
DK3091085T3
(da)
|
2010-10-06 |
2019-05-06 |
Inst Catalana Recerca Estudis Avancats |
Fremgangsmåde til at designe en terapi mod brystcancermetastase
|
|
EP2650682A1
(en)
|
2012-04-09 |
2013-10-16 |
Fundació Privada Institut de Recerca Biomèdica |
Method for the prognosis and treatment of cancer metastasis
|
|
CN104284895B
(zh)
|
2012-04-17 |
2016-08-31 |
安斯泰来制药株式会社 |
含氮双环式芳香族杂环化合物
|
|
BR112014030750A2
(pt)
|
2012-06-06 |
2017-08-22 |
Inst Catalana Recerca Estudis Avancats |
Método para diagnóstico, prognóstico e tratamento da metástase do câncer pulmonar
|
|
US10119171B2
(en)
|
2012-10-12 |
2018-11-06 |
Inbiomotion S.L. |
Method for the diagnosis, prognosis and treatment of prostate cancer metastasis
|
|
ES2906586T3
(es)
|
2012-10-12 |
2022-04-19 |
Inbiomotion Sl |
Método para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de próstata
|
|
EP2917216B1
(en)
|
2012-11-08 |
2017-10-18 |
Pfizer Inc |
Heteroaromatic compounds as dopamine d1 ligands
|
|
KR20150122731A
(ko)
|
2013-03-15 |
2015-11-02 |
펀다시오 인스티튜트 드 르세르카 바이오메디카 (아이알비 바르셀로나) |
암 전이의 예후 및 치료 방법
|
|
WO2014184679A2
(en)
|
2013-03-15 |
2014-11-20 |
Inbiomotion S.L. |
Method for the prognosis and treatment of renal cell carcinoma metastasis
|
|
AU2014333513B2
(en)
|
2013-10-09 |
2020-11-26 |
Fundacio Institut De Recerca Biomedica (Irb Barcelona) |
Method for the prognosis and treatment of metastasizing cancer of the bone originating from breast cancer
|
|
US9745317B2
(en)
|
2014-04-28 |
2017-08-29 |
Pfizer Inc. |
Heterocyclic compounds and their use as dopamine D1 ligands
|
|
CR20170076A
(es)
|
2014-08-04 |
2017-06-26 |
Nuevolution As |
Derivados de pirimidima sustituidos con heterociclilo opcionalmente condensados útiles para el tratamiento de enfermedades inflamatorias, metabólicas, oncológicas y autoinmunitarias
|
|
EP3229909B1
(en)
|
2014-12-11 |
2020-10-14 |
Inbiomotion S.L. |
Binding members for human c-maf
|
|
AU2016205361C1
(en)
|
2015-01-06 |
2021-04-08 |
Arena Pharmaceuticals, Inc. |
Methods of treating conditions related to the S1P1 receptor
|
|
PL3310760T3
(pl)
|
2015-06-22 |
2023-03-06 |
Arena Pharmaceuticals, Inc. |
Krystaliczna sól L-argininy kwasu (R)-2-(7-(4-cyklopentylo-3-(trifluorometylo)benzyloksy)- 1,2,3,4-tetrahydrocyklo-penta[b]indol-3-ilo)octowego do zastosowania w zaburzeniach związanych z receptorem S1P1
|
|
MX2018014279A
(es)
|
2016-05-25 |
2019-07-08 |
Inbiomotion Sl |
Tratamiento terapeutico de cancer de mama con base en estado de c-maf.
|
|
KR20190116416A
(ko)
|
2017-02-16 |
2019-10-14 |
아레나 파마슈티칼스, 인크. |
원발 담즙성 담관염을 치료하기 위한 화합물 및 방법
|
|
US11654153B2
(en)
|
2017-11-22 |
2023-05-23 |
Inbiomotion S.L. |
Therapeutic treatment of breast cancer based on c-MAF status
|
|
KR102054910B1
(ko)
*
|
2017-12-19 |
2019-12-12 |
한림제약(주) |
피롤로[2,3-d]피리미딘 유도체 또는 이의 염 및 이를 포함하는 약학 조성물
|
|
AU2019280822A1
(en)
|
2018-06-06 |
2021-01-07 |
Arena Pharmaceuticals, Inc. |
Methods of treating conditions related to the S1P1 receptor
|
|
AU2020250933A1
(en)
|
2019-04-05 |
2021-10-28 |
Centre Hospitalier Régional Et Universitaire De Brest |
Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning
|
|
AU2020405446A1
(en)
|
2019-12-20 |
2022-05-26 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
AU2020408107B2
(en)
|
2019-12-20 |
2026-04-23 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
EP4126874A1
(en)
|
2020-03-31 |
2023-02-08 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
US11613532B2
(en)
|
2020-03-31 |
2023-03-28 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
WO2024105159A1
(en)
*
|
2022-11-16 |
2024-05-23 |
University Of Zurich |
Ligands of the m6a-rna readers
|
|
CN121652156A
(zh)
*
|
2024-09-13 |
2026-03-13 |
常州强力电子新材料股份有限公司 |
一种氮杂腺嘌呤化合物及其制备方法与应用
|