|
GB0117396D0
(en)
|
2001-07-17 |
2001-09-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
AR036375A1
(es)
|
2001-08-30 |
2004-09-01 |
Novartis Ag |
Compuestos pirrolo [2,3-d] pirimidina -2- carbonitrilo, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de medicamentos
|
|
SE0201980D0
(sv)
*
|
2002-06-24 |
2002-06-24 |
Astrazeneca Ab |
Novel compounds
|
|
RS20050532A
(sr)
*
|
2003-01-14 |
2007-12-31 |
Arena Pharmaceuticals Inc., |
Derivati 1,2,3-trisupstituisanog arila i heteroarila kao modulatori metabolizma za profilaksu i tretman poremećaja povezanih sa njim, kao što su dijebetes i hiperglikemija
|
|
SI1599468T1
(sl)
|
2003-01-14 |
2008-02-29 |
Arena Pharm Inc |
1,2,3-trisubstituirani arilni in heteroarilni derivati kot modulatorji metabolizma ter profilaksa in zdravljenje motenj v zvezi z njim, kot diabetesain hiperglikemije
|
|
GB0308208D0
(en)
|
2003-04-09 |
2003-05-14 |
Glaxo Group Ltd |
Chemical compounds
|
|
AR045047A1
(es)
|
2003-07-11 |
2005-10-12 |
Arena Pharm Inc |
Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
|
|
KR20060056944A
(ko)
|
2003-07-14 |
2006-05-25 |
아레나 파마슈티칼스, 인크. |
대사 조절제로서 융합된 아릴 및 헤테로아릴 유도체 및이에 관련된 장애의 예방 또는 치료
|
|
EP1724264A1
(en)
*
|
2004-03-10 |
2006-11-22 |
Ono Pharmaceutical Co., Ltd. |
Nitriles and medicinal compositions containing the same as the active ingredient
|
|
TW200614993A
(en)
|
2004-06-11 |
2006-05-16 |
Akzo Nobel Nv |
4-phenyl-pyrimidine-2-carbonitrile derivatives
|
|
US7326715B2
(en)
|
2005-09-23 |
2008-02-05 |
N.V. Organon |
4-Phenyl-6-substituted-pyrimidine-2-carbonitrile derivatives
|
|
TW200745055A
(en)
*
|
2005-09-23 |
2007-12-16 |
Organon Nv |
4-Phenyl-6-substituted-pyrimidine-2-carbonitrile derivatives
|
|
TW200734338A
(en)
*
|
2006-01-16 |
2007-09-16 |
Organon Nv |
6-Phenyl-1H-imidazo [4,5-c] pyridine-4-carbonitrile derivatives
|
|
US7687515B2
(en)
|
2006-01-17 |
2010-03-30 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
CN101479269A
(zh)
*
|
2006-06-23 |
2009-07-08 |
阿斯利康(瑞典)有限公司 |
蝶啶衍生物及其作为组织蛋白酶抑制剂的用途
|
|
US20080269241A1
(en)
*
|
2007-02-15 |
2008-10-30 |
Darin Allen |
Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20090118274A1
(en)
*
|
2007-02-15 |
2009-05-07 |
Darin Allen |
Monocyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20090099157A1
(en)
*
|
2007-02-15 |
2009-04-16 |
Ameriks Michael K |
Tetrahydro-pyrazolo-pyridine thioether modulators of cathepsin s
|
|
US20080200454A1
(en)
*
|
2007-02-15 |
2008-08-21 |
Ameriks Michael K |
Carbon-linked tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20080207683A1
(en)
*
|
2007-02-15 |
2008-08-28 |
Darin Allen |
Biaryl-substituted tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
EP1972630A1
(en)
*
|
2007-03-02 |
2008-09-24 |
Glaxo Group Limited |
Purines as cysteine protease inhibitors
|
|
WO2008107368A1
(en)
*
|
2007-03-02 |
2008-09-12 |
Glaxo Group Limited |
Purines as cysteine protease inhibitors
|
|
US7932251B2
(en)
|
2007-07-16 |
2011-04-26 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
TW200911803A
(en)
*
|
2007-07-16 |
2009-03-16 |
Organon Nv |
6-phenyl-1H-imidazo [4,5-c] pyridine-4-carbonitrile derivatives
|
|
WO2009107767A1
(ja)
*
|
2008-02-29 |
2009-09-03 |
大日本住友製薬株式会社 |
Ｈ４受容体アンタゴニスト作用を有する新規２環性ピリミジン誘導体
|
|
EP2297153B1
(en)
*
|
2008-04-21 |
2015-05-27 |
Lexicon Pharmaceuticals, Inc. |
Limk2 inhibitors, compositions comprising them, and methods of their use
|
|
WO2010059418A1
(en)
*
|
2008-11-19 |
2010-05-27 |
The Government Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Services |
Substituted triazine and purine compounds, methods of inhibiting cruzain and rhodesain and methods of treating chagas disease and african trypanosomiasis
|
|
US8026236B2
(en)
|
2009-01-16 |
2011-09-27 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
TW201035094A
(en)
|
2009-01-16 |
2010-10-01 |
Organon Nv |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
GB0917934D0
(en)
|
2009-10-13 |
2009-11-25 |
Syngenta Ltd |
Herbicidal compounds
|
|
EP2523954B1
(en)
|
2010-01-15 |
2014-04-16 |
Merck Sharp & Dohme B.V. |
1h-[1,2,3]triazolo[4,5-c]pyridine-4- carbonitrile derivatives as cathepsin s inhibitors
|
|
CN103221410B
(zh)
|
2010-09-22 |
2017-09-15 |
艾尼纳制药公司 |
Gpr119受体调节剂和对与其相关的障碍的治疗
|
|
ES2562274T3
(es)
|
2010-10-06 |
2016-03-03 |
Fundació Institut De Recerca Biomèdica (Irb Barcelona) |
Procedimiento para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de mama
|
|
EP2650682A1
(en)
|
2012-04-09 |
2013-10-16 |
Fundació Privada Institut de Recerca Biomèdica |
Method for the prognosis and treatment of cancer metastasis
|
|
CA2870527A1
(en)
*
|
2012-04-17 |
2013-10-24 |
Astellas Pharma Inc. |
Nitrogenated bicyclic aromatic heterocyclic compound
|
|
EP3467124A1
(en)
|
2012-06-06 |
2019-04-10 |
Fundació Institut de Recerca Biomèdica IRB (Barcelona) |
Method for the diagnosis, prognosis and treatment of lung cancer metastasis
|
|
CA2888122A1
(en)
|
2012-10-12 |
2014-04-17 |
Inbiomotion S.L. |
Method for the diagnosis, prognosis and treatment of prostate cancer metastasis using c-maf
|
|
US10119171B2
(en)
|
2012-10-12 |
2018-11-06 |
Inbiomotion S.L. |
Method for the diagnosis, prognosis and treatment of prostate cancer metastasis
|
|
CA2889572C
(en)
|
2012-11-08 |
2019-03-05 |
Pfizer Inc. |
Heteroaromatic compounds as dopamine d1 ligands
|
|
US20160032400A1
(en)
|
2013-03-15 |
2016-02-04 |
Fundació Institut De Recerca Biomèdica (Irb Barcelona) |
Method for the prognosis and treatment of cancer metastasis
|
|
US20160032399A1
(en)
|
2013-03-15 |
2016-02-04 |
Inbiomotion S.L. |
Method for the Prognosis and Treatment of Renal Cell Carcinoma Metastasis
|
|
EP3524698A1
(en)
|
2013-10-09 |
2019-08-14 |
Fundació Institut de Recerca Biomèdica IRB (Barcelona) |
Method for the prognosis and treatment of cancer metastasis
|
|
CA2946990A1
(en)
|
2014-04-28 |
2015-11-05 |
Pfizer Inc. |
Heterocyclic compounds and their use as dopamine d1 ligands
|
|
MY195016A
(en)
|
2014-08-04 |
2023-01-03 |
Nuevolution As |
Optionally Fused Heterocyclyl-Substituted Derivatives of Pyrimidine Useful for The Treatment of Inflammatory, Metabolic, Oncologic and Autoimmune Diseases
|
|
KR20170093182A
(ko)
|
2014-12-11 |
2017-08-14 |
인바이오모션 에스.엘. |
인간 c-maf에 대한 결합 구성원
|
|
CA3002540C
(en)
|
2015-01-06 |
2023-11-07 |
Arena Pharmaceuticals, Inc. |
Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor
|
|
JP6838744B2
(ja)
|
2015-06-22 |
2021-03-03 |
アリーナ ファーマシューティカルズ， インコーポレイテッド |
Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩
|
|
CA3025264A1
(en)
|
2016-05-25 |
2017-11-30 |
Inbiomotion S.L. |
Therapeutic treatment of breast cancer based on c-maf status
|
|
CN110520124A
(zh)
|
2017-02-16 |
2019-11-29 |
艾尼纳制药公司 |
用于治疗原发性胆汁性胆管炎的化合物和方法
|
|
CA3082728A1
(en)
|
2017-11-22 |
2019-05-31 |
Inbiomotion S.L. |
Therapeutic treatment of breast cancer based on c-maf status
|
|
KR102054910B1
(ko)
*
|
2017-12-19 |
2019-12-12 |
한림제약(주) |
피롤로[2,3-d]피리미딘 유도체 또는 이의 염 및 이를 포함하는 약학 조성물
|
|
JP7397011B2
(ja)
|
2018-06-06 |
2023-12-12 |
アリーナ ファーマシューティカルズ， インコーポレイテッド |
Ｓ１ｐ１受容体に関連する状態を治療する方法
|
|
AU2020250933A1
(en)
|
2019-04-05 |
2021-10-28 |
Centre Hospitalier Régional Et Universitaire De Brest |
Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning
|
|
AU2020405446A1
(en)
|
2019-12-20 |
2022-05-26 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
BR112022012205A2
(pt)
|
2019-12-20 |
2022-09-13 |
Nuevolution As |
Compostos ativos para receptores nucleares
|
|
JP7713954B2
(ja)
|
2020-03-31 |
2025-07-28 |
ヌエヴォリューション・アクティーゼルスカブ |
核内受容体に対して活性な化合物
|
|
CA3174252A1
(en)
|
2020-03-31 |
2021-10-07 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
WO2024105159A1
(en)
*
|
2022-11-16 |
2024-05-23 |
University Of Zurich |
Ligands of the m6a-rna readers
|
|
CN121652156A
(zh)
*
|
2024-09-13 |
2026-03-13 |
常州强力电子新材料股份有限公司 |
一种氮杂腺嘌呤化合物及其制备方法与应用
|