|
GB0117396D0
(en)
|
2001-07-17 |
2001-09-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
AR036375A1
(es)
|
2001-08-30 |
2004-09-01 |
Novartis Ag |
Compuestos pirrolo [2,3-d] pirimidina -2- carbonitrilo, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de medicamentos
|
|
SE0201980D0
(sv)
*
|
2002-06-24 |
2002-06-24 |
Astrazeneca Ab |
Novel compounds
|
|
CN102558155A
(zh)
*
|
2003-01-14 |
2012-07-11 |
阿伦纳药品公司 |
作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗
|
|
EP1927594A1
(en)
|
2003-01-14 |
2008-06-04 |
Arena Pharmaceuticals, Inc. |
1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
|
GB0308208D0
(en)
|
2003-04-09 |
2003-05-14 |
Glaxo Group Ltd |
Chemical compounds
|
|
AR045047A1
(es)
|
2003-07-11 |
2005-10-12 |
Arena Pharm Inc |
Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
|
|
RS20060018A
(sr)
|
2003-07-14 |
2007-12-31 |
Arena Pharmaceuticals Inc., |
Derivati spojenih arila i heteroarila kao modulatori metabolizma u profilaksi i lečenju sa njima povezanih stanja
|
|
JPWO2005085210A1
(ja)
*
|
2004-03-10 |
2008-01-17 |
小野薬品工業株式会社 |
ニトリル化合物およびその化合物を有効成分として含有する医薬組成物
|
|
TW200614993A
(en)
|
2004-06-11 |
2006-05-16 |
Akzo Nobel Nv |
4-phenyl-pyrimidine-2-carbonitrile derivatives
|
|
US7326715B2
(en)
|
2005-09-23 |
2008-02-05 |
N.V. Organon |
4-Phenyl-6-substituted-pyrimidine-2-carbonitrile derivatives
|
|
TW200745055A
(en)
*
|
2005-09-23 |
2007-12-16 |
Organon Nv |
4-Phenyl-6-substituted-pyrimidine-2-carbonitrile derivatives
|
|
TW200734338A
(en)
*
|
2006-01-16 |
2007-09-16 |
Organon Nv |
6-Phenyl-1H-imidazo [4,5-c] pyridine-4-carbonitrile derivatives
|
|
US7687515B2
(en)
|
2006-01-17 |
2010-03-30 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
CN101479269A
(zh)
*
|
2006-06-23 |
2009-07-08 |
阿斯利康(瑞典)有限公司 |
蝶啶衍生物及其作为组织蛋白酶抑制剂的用途
|
|
US20080207683A1
(en)
*
|
2007-02-15 |
2008-08-28 |
Darin Allen |
Biaryl-substituted tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20090099157A1
(en)
*
|
2007-02-15 |
2009-04-16 |
Ameriks Michael K |
Tetrahydro-pyrazolo-pyridine thioether modulators of cathepsin s
|
|
US20090118274A1
(en)
*
|
2007-02-15 |
2009-05-07 |
Darin Allen |
Monocyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20080269241A1
(en)
*
|
2007-02-15 |
2008-10-30 |
Darin Allen |
Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
US20080200454A1
(en)
*
|
2007-02-15 |
2008-08-21 |
Ameriks Michael K |
Carbon-linked tetrahydro-pyrazolo-pyridine modulators of cathepsin s
|
|
EP1972630A1
(en)
*
|
2007-03-02 |
2008-09-24 |
Glaxo Group Limited |
Purines as cysteine protease inhibitors
|
|
US20100105652A1
(en)
*
|
2007-03-02 |
2010-04-29 |
Glaxo Group Limited |
Purines as cysteine protease inhibitors
|
|
US7932251B2
(en)
|
2007-07-16 |
2011-04-26 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
TW200911803A
(en)
*
|
2007-07-16 |
2009-03-16 |
Organon Nv |
6-phenyl-1H-imidazo [4,5-c] pyridine-4-carbonitrile derivatives
|
|
WO2009107767A1
(ja)
*
|
2008-02-29 |
2009-09-03 |
大日本住友製薬株式会社 |
Ｈ４受容体アンタゴニスト作用を有する新規２環性ピリミジン誘導体
|
|
EA019488B1
(ru)
*
|
2008-04-21 |
2014-04-30 |
Лексикон Фармасьютикалз, Инк. |
Ингибиторы limk2 и способы их применения
|
|
WO2010059418A1
(en)
*
|
2008-11-19 |
2010-05-27 |
The Government Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Services |
Substituted triazine and purine compounds, methods of inhibiting cruzain and rhodesain and methods of treating chagas disease and african trypanosomiasis
|
|
TW201035094A
(en)
|
2009-01-16 |
2010-10-01 |
Organon Nv |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
US8026236B2
(en)
|
2009-01-16 |
2011-09-27 |
N.V. Organon |
6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
|
|
GB0917934D0
(en)
|
2009-10-13 |
2009-11-25 |
Syngenta Ltd |
Herbicidal compounds
|
|
EP2523954B1
(en)
|
2010-01-15 |
2014-04-16 |
Merck Sharp & Dohme B.V. |
1h-[1,2,3]triazolo[4,5-c]pyridine-4- carbonitrile derivatives as cathepsin s inhibitors
|
|
EP3323818A1
(en)
|
2010-09-22 |
2018-05-23 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
JP6159254B2
(ja)
|
2010-10-06 |
2017-07-12 |
フンダシオ インスティトゥト デ レセルカ ビオメディカ（イエレベ バルセロナ） |
乳がん転移の診断、予後診断、および処置のための方法
|
|
EP2650682A1
(en)
|
2012-04-09 |
2013-10-16 |
Fundació Privada Institut de Recerca Biomèdica |
Method for the prognosis and treatment of cancer metastasis
|
|
JP6172143B2
(ja)
*
|
2012-04-17 |
2017-08-02 |
アステラス製薬株式会社 |
含窒素二環式芳香族へテロ環化合物
|
|
MX368513B
(es)
|
2012-06-06 |
2019-10-07 |
Fundacio Inst De Recerca Biomedica Irb Barcelona |
Métodos in vitro para el pronóstico, diagnóstico y diseño de una terapia de metástasis de cáncer de pulmón.
|
|
US10119171B2
(en)
|
2012-10-12 |
2018-11-06 |
Inbiomotion S.L. |
Method for the diagnosis, prognosis and treatment of prostate cancer metastasis
|
|
CN104995313A
(zh)
|
2012-10-12 |
2015-10-21 |
生物运动有限公司 |
使用c-maf的前列腺癌转移的诊断、预后和治疗的方法
|
|
SG11201502884TA
(en)
|
2012-11-08 |
2015-05-28 |
Pfizer |
Heteroaromatic compounds as dopamine d1 ligands
|
|
EP2971113B1
(en)
|
2013-03-15 |
2020-08-12 |
Fundació Institut de Recerca Biomèdica (IRB Barcelona) |
Method for the prognosis and treatment of cancer metastasis
|
|
WO2014184679A2
(en)
|
2013-03-15 |
2014-11-20 |
Inbiomotion S.L. |
Method for the prognosis and treatment of renal cell carcinoma metastasis
|
|
MX362041B
(es)
|
2013-10-09 |
2019-01-07 |
Fundacio Inst De Recerca Biomedica Irb Barcelona |
Método para el pronóstico y tratamiento de cáncer metastásico de los huesos originado de cáncer de mama.
|
|
WO2015166366A1
(en)
|
2014-04-28 |
2015-11-05 |
Pfizer Inc. |
Heterocyclic compounds and their use as dopamine d1 ligands
|
|
MY194204A
(en)
|
2014-08-04 |
2022-11-21 |
Nuevolution As |
Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
|
|
CA2967224C
(en)
|
2014-12-11 |
2023-08-22 |
Inbiomotion S.L. |
Binding members for human c-maf
|
|
EP4445956A3
(en)
|
2015-01-06 |
2024-12-04 |
Arena Pharmaceuticals, Inc. |
Compound for use in treating conditions related to the s1p1 receptor
|
|
EP3310760B8
(en)
|
2015-06-22 |
2022-10-19 |
Arena Pharmaceuticals, Inc. |
Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in s1p1 receptor-associated disorders
|
|
US11596642B2
(en)
|
2016-05-25 |
2023-03-07 |
Inbiomotion S.L. |
Therapeutic treatment of breast cancer based on c-MAF status
|
|
EP3582772A1
(en)
|
2017-02-16 |
2019-12-25 |
Arena Pharmaceuticals, Inc. |
Compounds and methods for treatment of primary biliary cholangitis
|
|
MX2020005182A
(es)
|
2017-11-22 |
2020-08-17 |
Inbiomotion Sl |
Tratamiento terapeutico del cancer de mama basado en el estado del c-maf.
|
|
KR102054910B1
(ko)
*
|
2017-12-19 |
2019-12-12 |
한림제약(주) |
피롤로[2,3-d]피리미딘 유도체 또는 이의 염 및 이를 포함하는 약학 조성물
|
|
KR102859841B1
(ko)
|
2018-06-06 |
2025-09-12 |
아레나 파마슈티칼스, 인크. |
S1p1 수용체와 관련된 병태의 치료 방법
|
|
US12350260B2
(en)
|
2019-04-05 |
2025-07-08 |
Universite De Bretagne Occidentale |
Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning
|
|
PE20230240A1
(es)
|
2019-12-20 |
2023-02-07 |
Nuevolution As |
Compuestos activos frente a receptores nucleares
|
|
JP2021098692A
(ja)
|
2019-12-20 |
2021-07-01 |
ヌエヴォリューション・アクティーゼルスカブＮｕｅｖｏｌｕｔｉｏｎ Ａ／Ｓ |
核内受容体に対して活性の化合物
|
|
US11613532B2
(en)
|
2020-03-31 |
2023-03-28 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
WO2021198955A1
(en)
|
2020-03-31 |
2021-10-07 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
WO2024105159A1
(en)
*
|
2022-11-16 |
2024-05-23 |
University Of Zurich |
Ligands of the m6a-rna readers
|