BRPI0716579A2 - Derivados de piridona com atividade antagonista ao mch e medicamentos que compreendem estes compostos - Google Patents

Derivados de piridona com atividade antagonista ao mch e medicamentos que compreendem estes compostos

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Publication number
BRPI0716579A2
BRPI0716579A2 BRPI0716579-0A2A BRPI0716579A BRPI0716579A2 BR PI0716579 A2 BRPI0716579 A2 BR PI0716579A2 BR PI0716579 A BRPI0716579 A BR PI0716579A BR PI0716579 A2 BRPI0716579 A2 BR PI0716579A2
Authority
BR
Brazil
Prior art keywords
mch
compounds
antagonist activity
medicinal products
pyridone derivatives
Prior art date
Application number
BRPI0716579-0A2A
Other languages
English (en)
Inventor
Dirk Stenkamp
Stephan Goerg Mueller
Thorsten Lehmann-Lintz
Gerald Juergen Roth
Joerg Kley
Klaus Rudolf
Armin Heckel
Marcus Schindler
Ralf Lotz
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of BRPI0716579A2 publication Critical patent/BRPI0716579A2/pt

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
BRPI0716579-0A2A 2006-08-25 2007-08-20 Derivados de piridona com atividade antagonista ao mch e medicamentos que compreendem estes compostos BRPI0716579A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06119523 2006-08-25
PCT/EP2007/058601 WO2008022979A1 (en) 2006-08-25 2007-08-20 New pyridone derivatives with mch antagonistic activity and medicaments comprising these compounds

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RU2009110446A (ru) 2010-09-27
CL2007002491A1 (es) 2008-01-18
MX2009000334A (es) 2009-01-28
US20080255083A1 (en) 2008-10-16
AR062510A1 (es) 2008-11-12
EP2069327A1 (en) 2009-06-17
NZ575520A (en) 2012-03-30
IL197128A0 (en) 2009-11-18
EP2383259A1 (en) 2011-11-02
TW200817366A (en) 2008-04-16
ZA200810404B (en) 2009-10-28
AU2007287601A1 (en) 2008-02-28
WO2008022979A1 (en) 2008-02-28
KR20090047542A (ko) 2009-05-12
US8067590B2 (en) 2011-11-29
US20120010185A1 (en) 2012-01-12
AU2007287601B2 (en) 2012-12-20
CN101506195A (zh) 2009-08-12
RU2453543C2 (ru) 2012-06-20
JP2010501518A (ja) 2010-01-21
JP5073746B2 (ja) 2012-11-14
EP2069327B1 (en) 2013-10-16

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