ZA200810404B - New pyridone derivatives with MCH antagonistic activity and medicaments comprising these compounds - Google Patents
New pyridone derivatives with MCH antagonistic activity and medicaments comprising these compoundsInfo
- Publication number
- ZA200810404B ZA200810404B ZA200810404A ZA200810404A ZA200810404B ZA 200810404 B ZA200810404 B ZA 200810404B ZA 200810404 A ZA200810404 A ZA 200810404A ZA 200810404 A ZA200810404 A ZA 200810404A ZA 200810404 B ZA200810404 B ZA 200810404B
- Authority
- ZA
- South Africa
- Prior art keywords
- medicaments
- compounds
- antagonistic activity
- pyridone derivatives
- mch antagonistic
- Prior art date
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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EP06119523 | 2006-08-25 |
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ZA200810404B true ZA200810404B (en) | 2009-10-28 |
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ZA200810404A ZA200810404B (en) | 2006-08-25 | 2008-12-09 | New pyridone derivatives with MCH antagonistic activity and medicaments comprising these compounds |
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US (2) | US8067590B2 (pt) |
EP (2) | EP2383259A1 (pt) |
JP (1) | JP5073746B2 (pt) |
KR (1) | KR20090047542A (pt) |
CN (1) | CN101506195A (pt) |
AR (1) | AR062510A1 (pt) |
AU (1) | AU2007287601B2 (pt) |
BR (1) | BRPI0716579A2 (pt) |
CA (1) | CA2657183A1 (pt) |
CL (1) | CL2007002491A1 (pt) |
IL (1) | IL197128A (pt) |
MX (1) | MX2009000334A (pt) |
NZ (1) | NZ575520A (pt) |
RU (1) | RU2453543C2 (pt) |
TW (1) | TW200817366A (pt) |
WO (1) | WO2008022979A1 (pt) |
ZA (1) | ZA200810404B (pt) |
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WO2009103478A1 (en) * | 2008-02-19 | 2009-08-27 | Boehringer Ingelheim International Gmbh | Pyridone and pyridazinone derivatives as mch antagonists |
CA2967254C (en) | 2008-02-29 | 2019-03-26 | Lantheus Medical Imaging, Inc. | Contrast agents for applications including imaging cancer |
MX2010012848A (es) | 2008-06-03 | 2011-03-01 | Intermune Inc | Compuestos y metodos para tratar trastornos inflamatorios y fibroticos. |
AR075401A1 (es) | 2009-02-13 | 2011-03-30 | Sanofi Aventis | Indanos sustituidos, procesos para su preparacion y uso de los mismos como un medicamento |
UY32443A (es) | 2009-02-13 | 2010-09-30 | Sanofi Aventis | Nuevos tetrahidronaftalenos, procesos para su preparación y uso de los mismos como medicamento. |
US8629158B2 (en) | 2009-07-01 | 2014-01-14 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
WO2011003021A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
EP2448585B1 (en) | 2009-07-01 | 2014-01-01 | Albany Molecular Research, Inc. | Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof |
US8618299B2 (en) | 2009-07-01 | 2013-12-31 | Albany Molecular Research, Inc. | Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof |
US20110021570A1 (en) | 2009-07-23 | 2011-01-27 | Nancy-Ellen Haynes | Pyridone glucokinase activators |
JP6092628B2 (ja) | 2010-02-08 | 2017-03-08 | ランセウス メディカル イメージング, インコーポレイテッド | 造影剤およびその中間体を合成するための方法および装置 |
WO2012088124A2 (en) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof |
US8697700B2 (en) | 2010-12-21 | 2014-04-15 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof |
SG2014013767A (en) | 2011-09-09 | 2014-05-29 | Lantheus Medical Imaging Inc | Compositions, methods, and systems for the synthesis and use of imaging agents |
US9365540B2 (en) | 2012-01-12 | 2016-06-14 | Takeda Pharmaceutical Company Limited | Benzimidazole derivatives as MCH receptor antagonists |
US8933079B2 (en) * | 2012-03-07 | 2015-01-13 | Boehringer Ingelheim International Gmbh | Pyridone and pyridazinone derivatives as anti-obesity agents |
WO2013168760A1 (ja) * | 2012-05-10 | 2013-11-14 | 武田薬品工業株式会社 | 芳香環化合物 |
JP6186434B2 (ja) | 2012-07-18 | 2017-08-23 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. | 窒素複素環誘導体及びその医薬品への応用 |
AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
EP3083584B1 (en) | 2013-12-19 | 2018-02-21 | Sunshine Lake Pharma Co., Ltd. | Nitrogenous heterocyclic derivatives and their application in the treatment of tissue fibrosis |
CN106459042B (zh) | 2014-04-02 | 2019-06-28 | 英特穆恩公司 | 抗纤维化吡啶酮类 |
US10540723B1 (en) | 2014-07-21 | 2020-01-21 | State Farm Mutual Automobile Insurance Company | Methods of providing insurance savings based upon telematics and usage-based insurance |
CN117538462B (zh) * | 2024-01-10 | 2024-03-26 | 地奥集团成都药业股份有限公司 | 一种氨氯地平贝那普利胶囊有关物质的检测方法 |
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CA2386474A1 (en) | 1999-09-20 | 2001-03-29 | Takeda Chemical Industries, Ltd. | Melanin concentrating hormone antagonist |
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MXPA04004830A (es) * | 2001-11-22 | 2004-07-30 | Ono Pharmaceutical Co | Compuestos derivados de piperidin-2-ona, y composiciones farmaceuticas que los contienen como ingredientes activos. |
WO2003059891A1 (en) | 2002-01-18 | 2003-07-24 | Pharmacia Corporation | Substituted pyridazinones as inhibitors of p38 |
ES2334990T3 (es) | 2002-02-14 | 2010-03-18 | Pharmacia Corporation | Piridinonas sustituidas como moduladores de p38 map quinasa. |
DE10238865A1 (de) | 2002-08-24 | 2004-03-11 | Boehringer Ingelheim International Gmbh | Neue Carbonsäureamid-Verbindungen mit MCH-antagonistischer Wirkung, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
DE10250708A1 (de) | 2002-10-31 | 2004-05-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE10250743A1 (de) | 2002-10-31 | 2004-05-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Amid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
US7183287B2 (en) | 2003-04-03 | 2007-02-27 | Pharmacia Corporation | Substituted pyrimidinones |
WO2005007632A1 (en) | 2003-07-18 | 2005-01-27 | Pharmacia Corporation | Substituted pyridazinones as inhibitors of p38 |
CL2004002050A1 (es) | 2003-08-13 | 2005-06-03 | Pharmacia Corp Sa Organizada B | Compuestos derivados de piridinonas sustituidas; su uso en el tratamiento de afecciones causadas o exacerbadas por actividad p38 map kinasa y/o tnf no regulada, tales como inflamaciones, tumores, sida y otros. |
DE10360745A1 (de) | 2003-12-23 | 2005-07-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Amid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
CA2558272C (en) | 2004-03-05 | 2011-02-15 | Banyu Pharmaceutical Co., Ltd. | Pyridone derivative |
DE102004010893A1 (de) | 2004-03-06 | 2005-09-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue ß-Ketoamid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017930A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017933A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017935A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017934A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017932A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
JPWO2007018248A1 (ja) | 2005-08-10 | 2009-02-19 | 萬有製薬株式会社 | ピリドン化合物 |
US7875633B2 (en) | 2005-08-24 | 2011-01-25 | Banyu Pharmaceutical Co., Ltd. | Phenylpyridone derivative |
JPWO2007029847A1 (ja) | 2005-09-07 | 2009-03-19 | 萬有製薬株式会社 | 二環性芳香族置換ピリドン誘導体 |
BRPI0617891A2 (pt) | 2005-10-26 | 2011-08-09 | Boehringer Ingelheim Int | compostos de (hetero)arila com atividade antagonista de mch, sais fisiologicamente aceitáveis dos mesmos, composição, composição farmacêutica bem como uso e preparação dos ditos compostos |
-
2007
- 2007-08-20 AU AU2007287601A patent/AU2007287601B2/en not_active Ceased
- 2007-08-20 EP EP11168245A patent/EP2383259A1/en not_active Withdrawn
- 2007-08-20 CA CA002657183A patent/CA2657183A1/en not_active Abandoned
- 2007-08-20 RU RU2009110446/04A patent/RU2453543C2/ru not_active IP Right Cessation
- 2007-08-20 BR BRPI0716579-0A2A patent/BRPI0716579A2/pt not_active IP Right Cessation
- 2007-08-20 CN CNA2007800316731A patent/CN101506195A/zh active Pending
- 2007-08-20 NZ NZ575520A patent/NZ575520A/en not_active IP Right Cessation
- 2007-08-20 MX MX2009000334A patent/MX2009000334A/es active IP Right Grant
- 2007-08-20 EP EP07819958.5A patent/EP2069327B1/en active Active
- 2007-08-20 JP JP2009525040A patent/JP5073746B2/ja active Active
- 2007-08-20 KR KR1020097006150A patent/KR20090047542A/ko not_active Application Discontinuation
- 2007-08-20 WO PCT/EP2007/058601 patent/WO2008022979A1/en active Application Filing
- 2007-08-24 TW TW096131555A patent/TW200817366A/zh unknown
- 2007-08-24 AR ARP070103758A patent/AR062510A1/es not_active Application Discontinuation
- 2007-08-24 US US11/844,842 patent/US8067590B2/en active Active
- 2007-08-24 CL CL2007002491A patent/CL2007002491A1/es unknown
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2008
- 2008-12-09 ZA ZA200810404A patent/ZA200810404B/xx unknown
-
2009
- 2009-02-19 IL IL197128A patent/IL197128A/en not_active IP Right Cessation
-
2011
- 2011-09-22 US US13/239,537 patent/US20120010185A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2657183A1 (en) | 2008-02-28 |
EP2069327B1 (en) | 2013-10-16 |
MX2009000334A (es) | 2009-01-28 |
CN101506195A (zh) | 2009-08-12 |
NZ575520A (en) | 2012-03-30 |
EP2069327A1 (en) | 2009-06-17 |
BRPI0716579A2 (pt) | 2013-10-08 |
JP2010501518A (ja) | 2010-01-21 |
TW200817366A (en) | 2008-04-16 |
RU2009110446A (ru) | 2010-09-27 |
US8067590B2 (en) | 2011-11-29 |
AU2007287601A1 (en) | 2008-02-28 |
WO2008022979A1 (en) | 2008-02-28 |
CL2007002491A1 (es) | 2008-01-18 |
JP5073746B2 (ja) | 2012-11-14 |
US20080255083A1 (en) | 2008-10-16 |
KR20090047542A (ko) | 2009-05-12 |
RU2453543C2 (ru) | 2012-06-20 |
IL197128A0 (en) | 2009-11-18 |
US20120010185A1 (en) | 2012-01-12 |
AR062510A1 (es) | 2008-11-12 |
EP2383259A1 (en) | 2011-11-02 |
IL197128A (en) | 2013-04-30 |
AU2007287601B2 (en) | 2012-12-20 |
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