JP2006503862A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006503862A5 JP2006503862A5 JP2004541383A JP2004541383A JP2006503862A5 JP 2006503862 A5 JP2006503862 A5 JP 2006503862A5 JP 2004541383 A JP2004541383 A JP 2004541383A JP 2004541383 A JP2004541383 A JP 2004541383A JP 2006503862 A5 JP2006503862 A5 JP 2006503862A5
- Authority
- JP
- Japan
- Prior art keywords
- oxo
- difluorophenyl
- phenyl
- acetyl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0202929A SE0202929D0 (sv) | 2002-10-03 | 2002-10-03 | Novel benzothiazepines and uses thereof |
| SE0203829A SE0203829D0 (sv) | 2002-12-18 | 2002-12-18 | Novel lactams and uses thereof |
| PCT/SE2003/001534 WO2004031154A1 (en) | 2002-10-03 | 2003-10-02 | Novel lactams and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010136105A Division JP2010248216A (ja) | 2002-10-03 | 2010-06-15 | 新規なラクタムおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006503862A JP2006503862A (ja) | 2006-02-02 |
| JP2006503862A5 true JP2006503862A5 (https=) | 2006-11-16 |
| JP4637584B2 JP4637584B2 (ja) | 2011-02-23 |
Family
ID=32072595
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004541383A Expired - Fee Related JP4637584B2 (ja) | 2002-10-03 | 2003-10-02 | 新規なラクタムおよびその使用 |
| JP2010136105A Pending JP2010248216A (ja) | 2002-10-03 | 2010-06-15 | 新規なラクタムおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010136105A Pending JP2010248216A (ja) | 2002-10-03 | 2010-06-15 | 新規なラクタムおよびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7294622B2 (https=) |
| EP (2) | EP1554250B1 (https=) |
| JP (2) | JP4637584B2 (https=) |
| AR (1) | AR041440A1 (https=) |
| AT (1) | ATE374187T1 (https=) |
| AU (1) | AU2003265202A1 (https=) |
| DE (1) | DE60316588T2 (https=) |
| DK (1) | DK1554250T3 (https=) |
| ES (1) | ES2291743T3 (https=) |
| PT (1) | PT1554250E (https=) |
| TW (1) | TW200502221A (https=) |
| WO (1) | WO2004031154A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004080983A1 (en) * | 2003-03-14 | 2004-09-23 | Astrazeneca Ab | Novel lactams and uses thereof |
| US7211573B2 (en) * | 2004-12-08 | 2007-05-01 | Hoffmann-La Roche Inc. | Malonamide derivatives |
| JP2008523141A (ja) * | 2004-12-14 | 2008-07-03 | アストラゼネカ・アクチエボラーグ | 新規の分子プローブ |
| GB2423085C (en) * | 2005-02-11 | 2011-11-09 | Cambridge Entpr Ltd | Ligands for G-protein coupled receptors |
| CA2628074C (en) | 2005-10-25 | 2014-01-14 | Shionogi & Co., Ltd. | Aminodihydrothiazine derivative |
| WO2007104933A1 (en) * | 2006-03-10 | 2007-09-20 | Astrazeneca Ab | Chemical compounds |
| ES2398531T3 (es) * | 2006-03-27 | 2013-03-20 | F. Hoffmann-La Roche Ag | Derivados de malonamida como inhibidores de gamma secretasa |
| CA2652669A1 (en) * | 2006-06-09 | 2007-12-21 | Merck & Co., Inc. | Benzazepinones as sodium channel blockers |
| US7919490B2 (en) * | 2006-10-04 | 2011-04-05 | Wyeth Llc | 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression |
| JP5383484B2 (ja) | 2007-04-24 | 2014-01-08 | 塩野義製薬株式会社 | 環式基で置換されたアミノジヒドロチアジン誘導体 |
| US8653067B2 (en) | 2007-04-24 | 2014-02-18 | Shionogi & Co., Ltd. | Pharmaceutical composition for treating Alzheimer's disease |
| JP5385904B2 (ja) * | 2007-08-14 | 2014-01-08 | イーライ リリー アンド カンパニー | γ−セクレターゼ阻害剤 |
| KR101324426B1 (ko) | 2008-06-13 | 2013-10-31 | 시오노기세야쿠 가부시키가이샤 | β 세크레타제 저해 작용을 갖는 황 함유 복소환 유도체 |
| CN102186841A (zh) | 2008-10-22 | 2011-09-14 | 盐野义制药株式会社 | 具有bace1抑制活性的2-氨基嘧啶-4-酮及2-氨基吡啶衍生物 |
| CN101735211B (zh) * | 2008-11-04 | 2012-11-14 | 复旦大学 | 2,3-二氢[1,5]苯并噻氮杂*类化合物或其盐在制备GSK-3β抑制剂中的用途 |
| US9023767B2 (en) * | 2009-05-07 | 2015-05-05 | Memorial Sloan-Kettering Cancer Center | γ-Secretase substrates and methods of use |
| UY32799A (es) * | 2009-07-24 | 2011-02-28 | Novartis Ag | Derivados de oxazina y su uso en el tratamiento de trastornos neurológicos |
| MX2012006491A (es) | 2009-12-11 | 2012-07-03 | Shionogi & Co | Derivados de oxazina. |
| CN103502466A (zh) | 2010-09-07 | 2014-01-08 | 斯隆－凯特林纪念癌症中心 | 用于γ-分泌酶测定的方法和组合物 |
| JP2014001142A (ja) * | 2010-10-05 | 2014-01-09 | Astellas Pharma Inc | シクロアルカン化合物 |
| BR112013008420A2 (pt) * | 2010-10-07 | 2016-06-28 | Takeda Pharmaceutical | composto, medicamento, e, uso do composito |
| EP2634188A4 (en) | 2010-10-29 | 2014-05-07 | Shionogi & Co | FUSIONED AMINODIHYDROPYRIMIDINE DERIVATIVE |
| JP5816630B2 (ja) | 2010-10-29 | 2015-11-18 | 塩野義製薬株式会社 | ナフチリジン誘導体 |
| US8883779B2 (en) | 2011-04-26 | 2014-11-11 | Shinogi & Co., Ltd. | Oxazine derivatives and a pharmaceutical composition for inhibiting BACE1 containing them |
| BR112015001830A2 (pt) * | 2012-08-09 | 2017-07-04 | Hoffmann La Roche | composto, uso de um composto, método para o tratamento ou profilaxia de câncer e invenção |
| EP2912035A4 (en) | 2012-10-24 | 2016-06-15 | Shionogi & Co | DERIVATIVES OF DIHYDROOXAZINE OR OXAZEPINE HAVING BACE1 INHIBITING ACTIVITY |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04503073A (ja) | 1989-01-31 | 1992-06-04 | アボツト・ラボラトリーズ | アナフィラトキシン受容体リガンド |
| US5936065A (en) | 1993-12-06 | 1999-08-10 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using the same |
| EP0900791A1 (en) | 1995-12-27 | 1999-03-10 | Ono Pharmaceutical Co., Ltd. | Tetrazole derivatives and drugs containing the same as the active ingredient |
| GB9621836D0 (en) | 1996-10-19 | 1996-12-11 | Zeneca Ltd | Peptide compounds |
| HUP0001232A3 (en) | 1996-12-23 | 2001-02-28 | Elan Pharmaceuticals Inc San F | Cycloalkyl, lactam, lactone derivatives and their thio analogues inhibiting betha-amyloid peptide release and/or its synthesis and pharmaceutical compositions containing the compounds |
| JP2002518481A (ja) * | 1998-06-22 | 2002-06-25 | エラン ファーマシューティカルズ，インコーポレイテッド | β−アミロイドペプチドの放出および／またはその合成を阻害するための化合物 |
| AU5204799A (en) * | 1998-06-22 | 2000-01-10 | Elan Pharmaceuticals, Inc. | Compounds for inhibiting beta-amyloid peptide release and/or its synthesis |
| WO1999067221A1 (en) | 1998-06-22 | 1999-12-29 | Elan Pharmaceuticals, Inc. | Compounds for inhibiting beta-amyloid peptide release and/or its synthesis |
| WO2000002903A1 (en) | 1998-07-10 | 2000-01-20 | Cytel Corporation | Cs-1 peptidomimetics, compositions and methods of using the same |
| HRP990246A2 (en) | 1998-08-07 | 2000-06-30 | Du Pont Pharm Co | Succinoylamino benzodiazepines as inhibitors of a beta protein production |
| EP1131634A2 (en) | 1998-09-30 | 2001-09-12 | Elan Pharmaceuticals, Inc. | Determining the mechanism of beta-amyloid peptide generation |
| WO2000038618A2 (en) * | 1998-12-24 | 2000-07-06 | Du Pont Pharmaceuticals Company | SUCCINOYLAMINO BENZODIAZEPINES AS INHIBITORS OF Aβ PROTEIN PRODUCTION |
| JP2001030342A (ja) | 1999-07-23 | 2001-02-06 | Japan Polychem Corp | ポリオレフィン製延伸ブロー成形用インモールドラベル及びそのラベルを熱融着させた成形体 |
| CA2377221A1 (en) * | 1999-09-13 | 2001-03-22 | Bristol-Myers Squibb Pharma Company | Hydroxyalkanoyl aminolactams and related structures as inhibitors of a.beta. protein production |
| AU2001243601A1 (en) | 2000-03-10 | 2001-09-24 | Ariad Pharmaceuticals, Inc. | Caprolactam derivatives and uses thereof |
| WO2001072324A1 (en) | 2000-03-28 | 2001-10-04 | Bristol-Myers Squibb Pharma Company | Lactams as inhibitors of a-beta protein production |
| WO2004080983A1 (en) | 2003-03-14 | 2004-09-23 | Astrazeneca Ab | Novel lactams and uses thereof |
| US7060698B2 (en) | 2003-05-19 | 2006-06-13 | Hoffmann-La Roche Inc. | Benzoxazepinone derivatives |
| JP2008523141A (ja) | 2004-12-14 | 2008-07-03 | アストラゼネカ・アクチエボラーグ | 新規の分子プローブ |
-
2003
- 2003-09-29 TW TW092126851A patent/TW200502221A/zh unknown
- 2003-09-30 AR ARP030103560A patent/AR041440A1/es not_active Application Discontinuation
- 2003-10-02 EP EP03799234A patent/EP1554250B1/en not_active Expired - Lifetime
- 2003-10-02 DE DE60316588T patent/DE60316588T2/de not_active Expired - Lifetime
- 2003-10-02 EP EP07012660A patent/EP1845089A1/en not_active Withdrawn
- 2003-10-02 WO PCT/SE2003/001534 patent/WO2004031154A1/en not_active Ceased
- 2003-10-02 ES ES03799234T patent/ES2291743T3/es not_active Expired - Lifetime
- 2003-10-02 DK DK03799234T patent/DK1554250T3/da active
- 2003-10-02 JP JP2004541383A patent/JP4637584B2/ja not_active Expired - Fee Related
- 2003-10-02 PT PT03799234T patent/PT1554250E/pt unknown
- 2003-10-02 AT AT03799234T patent/ATE374187T1/de not_active IP Right Cessation
- 2003-10-02 US US10/528,640 patent/US7294622B2/en not_active Expired - Fee Related
- 2003-10-02 AU AU2003265202A patent/AU2003265202A1/en not_active Abandoned
-
2007
- 2007-08-24 US US11/844,451 patent/US20080076752A1/en not_active Abandoned
-
2009
- 2009-01-26 US US12/359,465 patent/US7858776B2/en not_active Expired - Fee Related
-
2010
- 2010-06-15 JP JP2010136105A patent/JP2010248216A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006503862A5 (https=) | ||
| JP2005524628A5 (https=) | ||
| JP5896601B2 (ja) | セラミド誘導体を用いる多発性嚢胞腎疾患の治療方法 | |
| JP2004504404A5 (https=) | ||
| RU2000114635A (ru) | Бензотиазольные ингибиторы протеинтирозинкиназ | |
| JP2005533826A5 (https=) | ||
| RU2003104013A (ru) | Бициклические пирролиламиды в качестве ингибиторов гликогенфосфорилазы | |
| EA036062B1 (ru) | Лекарственное средство для предупреждения и/или лечения поликистозной болезни почек | |
| JP2009541484A (ja) | ５ｈｔ６モジュレーターおよびコリンエステラーゼインヒビターを含む組み合わせ | |
| WO2019046287A1 (en) | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HEPATITIS B | |
| US11345696B2 (en) | Compounds and methods of treating or ameliorating an IL-1R-mediated disease or disorder using same | |
| JP2008538582A (ja) | 精神病性障害の治療または予防のための新規の治療的組み合わせ | |
| JP2008503575A5 (https=) | ||
| JP2023506488A5 (https=) | ||
| ES2297850T3 (es) | Aplicacion de derivados de pirrolidina en la preparacion de medicamentos destinados al tratamiento del abuso de drogas. | |
| JP2006520396A5 (https=) | ||
| RU2001102617A (ru) | Соединения, обладающие свойствами высвобождения гормона роста | |
| HUT72070A (en) | Pharmaceutical compositions containing melatonin derivatives for treating desynchronization disorders | |
| RU2011105463A (ru) | ФАРМАЦЕВТИЧЕСКИЙ ПРОДУКТ, СОДЕРЖАЩИЙ АНТАГОНИСТ МУСКАРИНОВОГО РЕЦЕПТОРА И АГОНИСТ β2-АДРЕНОРЕЦЕПТОРА | |
| US5935980A (en) | Use of pyrrolidine derivatives in the treatment of alcoholism | |
| JP2022528481A (ja) | ピモジドとメトトレキサートの医薬組成物、及びその使用 | |
| RU2006126828A (ru) | Антагонисты нейрокининового рецептора nk-1 для выхода из наркоза | |
| CN1655822A (zh) | 含有acat抑制剂和胰岛素抵抗性改善剂的药用组合物 | |
| RU2022113054A (ru) | Нитрилсодержащие противовирусные соединения | |
| JP2712143B2 (ja) | 血小板凝集抑制組成物 |