JP2006501820A - 修飾ｇｌｐ−１受容体アゴニストおよびそれらの薬理学的使用法 - Google Patents

修飾ｇｌｐ−１受容体アゴニストおよびそれらの薬理学的使用法 Download PDF

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JP2006501820A
JP2006501820A JP2004534751A JP2004534751A JP2006501820A JP 2006501820 A JP2006501820 A JP 2006501820A JP 2004534751 A JP2004534751 A JP 2004534751A JP 2004534751 A JP2004534751 A JP 2004534751A JP 2006501820 A JP2006501820 A JP 2006501820A
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polypeptide
glp
diabetes
insulin
agents
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JP2006501820A5 (https=
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パン，クラーク
ウエラン，ジエイムズ・ピー
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バイエル・フアーマシユーチカルズ・コーポレーシヨン
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2004534751A 2002-09-06 2003-09-04 修飾ｇｌｐ−１受容体アゴニストおよびそれらの薬理学的使用法 Pending JP2006501820A (ja)

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US40869602P 2002-09-06 2002-09-06
US43936903P 2003-01-09 2003-01-09
PCT/US2003/028093 WO2004022004A2 (en) 2002-09-06 2003-09-04 Modified glp-1 receptor agonists and their pharmacological methods of use

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JP2006501820A true JP2006501820A (ja) 2006-01-19
JP2006501820A5 JP2006501820A5 (https=) 2006-09-14

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EP (1) EP1539210A4 (https=)
JP (1) JP2006501820A (https=)
AU (1) AU2003273300A1 (https=)
CA (1) CA2497794A1 (https=)
WO (1) WO2004022004A2 (https=)

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JP2012521201A (ja) * 2009-03-26 2012-09-13 ザ ホン コン ポリテクニック ユニバーシティ アルギナーゼの部位指定的ペグ化並びにその抗がん剤及び抗ウイルス剤としての使用
JP2013518035A (ja) * 2010-01-21 2013-05-20 サノフイ 代謝症候群を処置するための医薬組成物
KR20150093167A (ko) * 2012-12-11 2015-08-17 메디뮨 리미티드 비만 치료를 위한 글루카곤/glp-1 작용제
JP2016512213A (ja) * 2013-03-14 2016-04-25 メディミューン リミテッド 肥満の治療のためのペグ化グルカゴン及びｇｌｐ−１コアゴニスト

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JP2009536166A (ja) * 2006-05-10 2009-10-08 バイオコンパティブルズ ユーケー リミテッド Ｇｌｐ−１ペプチドを含む球状のマイクロカプセル、その製造及び使用
JP2012521201A (ja) * 2009-03-26 2012-09-13 ザ ホン コン ポリテクニック ユニバーシティ アルギナーゼの部位指定的ペグ化並びにその抗がん剤及び抗ウイルス剤としての使用
JP2013518035A (ja) * 2010-01-21 2013-05-20 サノフイ 代謝症候群を処置するための医薬組成物
JP2018095659A (ja) * 2010-01-21 2018-06-21 サノフイ 代謝症候群を処置するための医薬組成物
KR20150093167A (ko) * 2012-12-11 2015-08-17 메디뮨 리미티드 비만 치료를 위한 글루카곤/glp-1 작용제
JP2016501256A (ja) * 2012-12-11 2016-01-18 メディミューン リミテッド 肥満を治療するためのグルカゴン／ｇｌｐ−１アゴニスト
KR102080366B1 (ko) 2012-12-11 2020-02-21 메디뮨 리미티드 비만 치료를 위한 글루카곤/glp-1 작용제
JP2016512213A (ja) * 2013-03-14 2016-04-25 メディミューン リミテッド 肥満の治療のためのペグ化グルカゴン及びｇｌｐ−１コアゴニスト

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