JP2005533106A5 - - Google Patents
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- Publication number
- JP2005533106A5 JP2005533106A5 JP2004521510A JP2004521510A JP2005533106A5 JP 2005533106 A5 JP2005533106 A5 JP 2005533106A5 JP 2004521510 A JP2004521510 A JP 2004521510A JP 2004521510 A JP2004521510 A JP 2004521510A JP 2005533106 A5 JP2005533106 A5 JP 2005533106A5
- Authority
- JP
- Japan
- Prior art keywords
- fatty acid
- film
- film composition
- composition
- forming polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 32
- 235000014113 dietary fatty acids Nutrition 0.000 claims 18
- 239000000194 fatty acid Substances 0.000 claims 18
- 229930195729 fatty acid Natural products 0.000 claims 18
- 229920000642 polymer Polymers 0.000 claims 10
- 229940079593 drug Drugs 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 8
- -1 fatty acid ester Chemical class 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 238000012377 drug delivery Methods 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 3
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 208000010412 Glaucoma Diseases 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 claims 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- 229930012538 Paclitaxel Natural products 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 229960001592 paclitaxel Drugs 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000004584 polyacrylic acid Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39584002P | 2002-07-15 | 2002-07-15 | |
| US43272102P | 2002-12-12 | 2002-12-12 | |
| PCT/US2003/020706 WO2004006889A1 (en) | 2002-07-15 | 2003-06-30 | Bioerodible film for ophthalmic drug delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005533106A JP2005533106A (ja) | 2005-11-04 |
| JP2005533106A5 true JP2005533106A5 (https=) | 2006-07-06 |
| JP4454019B2 JP4454019B2 (ja) | 2010-04-21 |
Family
ID=30118549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004521510A Expired - Fee Related JP4454019B2 (ja) | 2002-07-15 | 2003-06-30 | 眼薬送達のための生体侵食性フィルム |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8084054B2 (https=) |
| EP (1) | EP1521572B1 (https=) |
| JP (1) | JP4454019B2 (https=) |
| KR (1) | KR101003514B1 (https=) |
| CN (1) | CN100500221C (https=) |
| AT (1) | ATE424187T1 (https=) |
| AU (1) | AU2003247671B2 (https=) |
| CA (1) | CA2491312C (https=) |
| CY (1) | CY1109606T1 (https=) |
| DE (1) | DE60326455D1 (https=) |
| DK (1) | DK1521572T3 (https=) |
| ES (1) | ES2321083T3 (https=) |
| MX (1) | MXPA05000631A (https=) |
| PL (1) | PL206379B1 (https=) |
| PT (1) | PT1521572E (https=) |
| SI (1) | SI1521572T1 (https=) |
| WO (1) | WO2004006889A1 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006227116A1 (en) * | 2005-03-21 | 2006-09-28 | Santen Pharmaceutical Co., Ltd. | Drug delivery systems for treatment of diseases or conditions |
| AU2009246520B2 (en) | 2008-05-12 | 2012-04-19 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US9095404B2 (en) | 2008-05-12 | 2015-08-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US10064819B2 (en) | 2008-05-12 | 2018-09-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| AU2010208046B2 (en) | 2009-01-29 | 2014-10-02 | Forsight Vision4, Inc. | Posterior segment drug delivery |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| WO2013022801A1 (en) | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| MX2013001116A (es) * | 2010-07-29 | 2013-06-05 | Santen Pharma Co Ltd | Cuerpo para soporte de farmaco, y metodo para producir el mismo. |
| CN103209664A (zh) | 2010-08-05 | 2013-07-17 | 弗赛特影像4股份有限公司 | 可植入的治疗装置 |
| AU2011285548B2 (en) | 2010-08-05 | 2014-02-06 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
| EP3861969A1 (en) | 2010-08-05 | 2021-08-11 | ForSight Vision4, Inc. | Injector apparatus for drug delivery |
| WO2012068549A2 (en) | 2010-11-19 | 2012-05-24 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| WO2012153870A1 (ja) * | 2011-05-11 | 2012-11-15 | 帝人株式会社 | 緑内障治療材 |
| US20120302954A1 (en) * | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
| US10398592B2 (en) | 2011-06-28 | 2019-09-03 | Forsight Vision4, Inc. | Diagnostic methods and apparatus |
| PT2755600T (pt) | 2011-09-16 | 2021-04-19 | Forsight Vision4 Inc | Aparelhos de troca de fluidos |
| WO2013116061A1 (en) | 2012-02-03 | 2013-08-08 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| WO2014018075A1 (en) | 2012-07-23 | 2014-01-30 | Crayola, Llc | Dissolvable films and methods of using the same |
| WO2014152959A1 (en) | 2013-03-14 | 2014-09-25 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| CN105246438B (zh) | 2013-03-28 | 2018-01-26 | 弗赛特影像4股份有限公司 | 用于输送治疗物质的眼科植入物 |
| ES2803102T3 (es) | 2014-07-15 | 2021-01-22 | Forsight Vision4 Inc | Dispositivo de administración de implante ocular |
| RU2017105844A (ru) | 2014-08-08 | 2018-09-11 | Форсайт Вижн4, Инк. | Стабильные и растворимые составы ингибиторов рецепторных тирозинкиназ и способы их получения |
| CN110478119B (zh) | 2014-11-10 | 2022-04-15 | 弗赛特影像4股份有限公司 | 可膨胀药物递送装置和使用方法 |
| WO2017087902A1 (en) | 2015-11-20 | 2017-05-26 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
| CN113017981B (zh) | 2016-04-05 | 2023-07-25 | 弗赛特影像4股份有限公司 | 药物递送装置 |
| CN111655206B (zh) | 2017-11-21 | 2022-10-14 | 弗赛特影像4股份有限公司 | 用于可扩展端口递送系统的流体交换装置及使用方法 |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
| AU2023345389A1 (en) * | 2022-09-23 | 2025-04-17 | Madd Ophthalmics Ltd. | Mucoadhesive drug delivery systems and methods of use |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6042766B2 (ja) | 1978-12-09 | 1985-09-25 | 日本化薬株式会社 | 基剤 |
| GB8524421D0 (en) | 1985-10-03 | 1985-11-06 | Boots Co Plc | Therapeutic agents |
| US4853224A (en) * | 1987-12-22 | 1989-08-01 | Visionex | Biodegradable ocular implants |
| US4880636A (en) * | 1988-05-13 | 1989-11-14 | Franz Robert M | Film coated tablet of ranitidine HCl |
| US4865846A (en) * | 1988-06-03 | 1989-09-12 | Kaufman Herbert E | Drug delivery system |
| US6117425A (en) | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
| UA34430C2 (uk) | 1991-05-13 | 2001-03-15 | Дзе Бутс Компані Плс | S(-)-2-(4-ізобутилфеніл)пропіонат натрію дигідрат, придатний для лікування запалення, болю і гіпертермії, фармацевтична композиція на його основі та спосіб одержання s(-)-2-(4-ізобутилфеніл)пропіонату натрію |
| GB9213077D0 (en) | 1992-06-19 | 1992-08-05 | Erba Carlo Spa | Polymerbound taxol derivatives |
| US5614549A (en) | 1992-08-21 | 1997-03-25 | Enzon, Inc. | High molecular weight polymer-based prodrugs |
| US5916596A (en) | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| US6537579B1 (en) | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
| US5362478A (en) | 1993-03-26 | 1994-11-08 | Vivorx Pharmaceuticals, Inc. | Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell |
| US6096331A (en) | 1993-02-22 | 2000-08-01 | Vivorx Pharmaceuticals, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
| US5439686A (en) | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
| US5665382A (en) | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of pharmaceutically active agents for in vivo delivery |
| NZ262679A (en) | 1993-02-22 | 1997-08-22 | Vivorx Pharmaceuticals Inc | Compositions for in vivo delivery of pharmaceutical agents where the agents are contained in a polymeric shell |
| US5886026A (en) | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
| TW406020B (en) | 1993-09-29 | 2000-09-21 | Bristol Myers Squibb Co | Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent |
| US5433951A (en) | 1993-10-13 | 1995-07-18 | Bristol-Myers Squibb Company | Sustained release formulation containing captopril and method |
| US5484608A (en) * | 1994-03-28 | 1996-01-16 | Pharmavene, Inc. | Sustained-release drug delivery system |
| US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| US6063116A (en) | 1994-10-26 | 2000-05-16 | Medarex, Inc. | Modulation of cell proliferation and wound healing |
| US5783178A (en) | 1994-11-18 | 1998-07-21 | Supratek Pharma. Inc. | Polymer linked biological agents |
| US6369116B1 (en) | 1995-06-02 | 2002-04-09 | Oculex Pharmaceuticals, Inc. | Composition and method for treating glaucoma |
| RU2086218C1 (ru) | 1995-07-26 | 1997-08-10 | Санкт-Петербургская медицинская академия последипломного образования | Способ лечения глаукомы |
| US5736152A (en) | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| FR2748209B1 (fr) * | 1996-05-06 | 1998-06-05 | Adir | Composition pharmaceutique a base de matrices lipophiles stabilisees pour la liberation controlee de principes actifs |
| DE69734060T2 (de) | 1996-05-24 | 2006-06-29 | Angiotech Pharmaceuticals, Inc., Vancouver | Zubereitungen und verfahren zur behandlung oder prävention von krankheiten der körperpassagewege |
| US5888493A (en) * | 1996-12-05 | 1999-03-30 | Sawaya; Assad S. | Ophthalmic aqueous gel formulation and related methods |
| PT1023050E (pt) | 1997-06-27 | 2013-12-04 | Abraxis Bioscience Llc | Novas formulações de agentes farmacológicos, métodos para a sua preparação e métodos para a sua utilização |
| US6004573A (en) | 1997-10-03 | 1999-12-21 | Macromed, Inc. | Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
| US20020164374A1 (en) | 1997-10-29 | 2002-11-07 | John Jackson | Polymeric systems for drug delivery and uses thereof |
| US6146659A (en) | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
| US6017948A (en) | 1998-10-30 | 2000-01-25 | Supergen, Inc. | Water-miscible pharmaceutical compositions |
| ES2204531T3 (es) * | 1999-03-16 | 2004-05-01 | Merck Patent Gmbh | Composicion que comprende isoquercetina y acido ascorbico en una forma de liberacion sostenida. |
| EP1171117A4 (en) | 1999-04-22 | 2002-08-07 | American Bioscience Inc | LONG-TERM ADMINISTRATION OF PHARMACOLOGICALLY ACTIVE AGENTS |
| US6306120B1 (en) | 1999-06-07 | 2001-10-23 | Ben Gee Tan | Applicator and method for delivery of mitomycin to eye tissues during glaucoma filtering surgery |
| US6375963B1 (en) * | 1999-06-16 | 2002-04-23 | Michael A. Repka | Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof |
| JP2004529934A (ja) * | 2001-05-01 | 2004-09-30 | アンジオテック ファーマシューティカルズ，インコーポレイテッド | 抗微小管剤およびポリペプチドまたはポリサッカリドを含む組成物、ならびに炎症状態を処置するための医薬品の調製のためのそれらの組成物の使用 |
| US20040058313A1 (en) * | 2002-04-24 | 2004-03-25 | Abreu Marcio Marc | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
-
2003
- 2003-06-30 AT AT03764333T patent/ATE424187T1/de active
- 2003-06-30 US US10/610,090 patent/US8084054B2/en not_active Expired - Fee Related
- 2003-06-30 SI SI200331565T patent/SI1521572T1/sl unknown
- 2003-06-30 DK DK03764333T patent/DK1521572T3/da active
- 2003-06-30 PL PL374764A patent/PL206379B1/pl not_active IP Right Cessation
- 2003-06-30 ES ES03764333T patent/ES2321083T3/es not_active Expired - Lifetime
- 2003-06-30 KR KR1020057000486A patent/KR101003514B1/ko not_active Expired - Fee Related
- 2003-06-30 JP JP2004521510A patent/JP4454019B2/ja not_active Expired - Fee Related
- 2003-06-30 EP EP03764333A patent/EP1521572B1/en not_active Expired - Lifetime
- 2003-06-30 WO PCT/US2003/020706 patent/WO2004006889A1/en not_active Ceased
- 2003-06-30 AU AU2003247671A patent/AU2003247671B2/en not_active Ceased
- 2003-06-30 CA CA2491312A patent/CA2491312C/en not_active Expired - Fee Related
- 2003-06-30 CN CNB038167921A patent/CN100500221C/zh not_active Expired - Fee Related
- 2003-06-30 DE DE60326455T patent/DE60326455D1/de not_active Expired - Lifetime
- 2003-06-30 PT PT03764333T patent/PT1521572E/pt unknown
- 2003-06-30 MX MXPA05000631A patent/MXPA05000631A/es active IP Right Grant
-
2009
- 2009-04-28 CY CY20091100469T patent/CY1109606T1/el unknown
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