SI1521572T1 - Film, ki se da bioerodirati, za dajanje oftalmičnega zdravila - Google Patents

Film, ki se da bioerodirati, za dajanje oftalmičnega zdravila

Info

Publication number
SI1521572T1
SI1521572T1 SI200331565T SI200331565T SI1521572T1 SI 1521572 T1 SI1521572 T1 SI 1521572T1 SI 200331565 T SI200331565 T SI 200331565T SI 200331565 T SI200331565 T SI 200331565T SI 1521572 T1 SI1521572 T1 SI 1521572T1
Authority
SI
Slovenia
Prior art keywords
drug delivery
ophthalmic drug
film
bioerodible
bioerodible film
Prior art date
Application number
SI200331565T
Other languages
English (en)
Slovenian (sl)
Inventor
Bhagwati P Kabra
Janet D Howie
Youqin Tian
David Allen Marsh
Gustav Graff
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of SI1521572T1 publication Critical patent/SI1521572T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts or implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
SI200331565T 2002-07-15 2003-06-30 Film, ki se da bioerodirati, za dajanje oftalmičnega zdravila SI1521572T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39584002P 2002-07-15 2002-07-15
US43272102P 2002-12-12 2002-12-12
EP03764333A EP1521572B1 (en) 2002-07-15 2003-06-30 Bioerodible film for ophthalmic drug delivery
PCT/US2003/020706 WO2004006889A1 (en) 2002-07-15 2003-06-30 Bioerodible film for ophthalmic drug delivery

Publications (1)

Publication Number Publication Date
SI1521572T1 true SI1521572T1 (sl) 2009-06-30

Family

ID=30118549

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200331565T SI1521572T1 (sl) 2002-07-15 2003-06-30 Film, ki se da bioerodirati, za dajanje oftalmičnega zdravila

Country Status (17)

Country Link
US (1) US8084054B2 (https=)
EP (1) EP1521572B1 (https=)
JP (1) JP4454019B2 (https=)
KR (1) KR101003514B1 (https=)
CN (1) CN100500221C (https=)
AT (1) ATE424187T1 (https=)
AU (1) AU2003247671B2 (https=)
CA (1) CA2491312C (https=)
CY (1) CY1109606T1 (https=)
DE (1) DE60326455D1 (https=)
DK (1) DK1521572T3 (https=)
ES (1) ES2321083T3 (https=)
MX (1) MXPA05000631A (https=)
PL (1) PL206379B1 (https=)
PT (1) PT1521572E (https=)
SI (1) SI1521572T1 (https=)
WO (1) WO2004006889A1 (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006227116A1 (en) * 2005-03-21 2006-09-28 Santen Pharmaceutical Co., Ltd. Drug delivery systems for treatment of diseases or conditions
AU2009246520B2 (en) 2008-05-12 2012-04-19 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
AU2010208046B2 (en) 2009-01-29 2014-10-02 Forsight Vision4, Inc. Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
WO2013022801A1 (en) 2011-08-05 2013-02-14 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
MX2013001116A (es) * 2010-07-29 2013-06-05 Santen Pharma Co Ltd Cuerpo para soporte de farmaco, y metodo para producir el mismo.
CN103209664A (zh) 2010-08-05 2013-07-17 弗赛特影像4股份有限公司 可植入的治疗装置
AU2011285548B2 (en) 2010-08-05 2014-02-06 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
EP3861969A1 (en) 2010-08-05 2021-08-11 ForSight Vision4, Inc. Injector apparatus for drug delivery
WO2012068549A2 (en) 2010-11-19 2012-05-24 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
WO2012153870A1 (ja) * 2011-05-11 2012-11-15 帝人株式会社 緑内障治療材
US20120302954A1 (en) * 2011-05-25 2012-11-29 Zhao Jonathon Z Expandable devices coated with a paclitaxel composition
US10398592B2 (en) 2011-06-28 2019-09-03 Forsight Vision4, Inc. Diagnostic methods and apparatus
PT2755600T (pt) 2011-09-16 2021-04-19 Forsight Vision4 Inc Aparelhos de troca de fluidos
WO2013116061A1 (en) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
WO2014018075A1 (en) 2012-07-23 2014-01-30 Crayola, Llc Dissolvable films and methods of using the same
WO2014152959A1 (en) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
CN105246438B (zh) 2013-03-28 2018-01-26 弗赛特影像4股份有限公司 用于输送治疗物质的眼科植入物
ES2803102T3 (es) 2014-07-15 2021-01-22 Forsight Vision4 Inc Dispositivo de administración de implante ocular
RU2017105844A (ru) 2014-08-08 2018-09-11 Форсайт Вижн4, Инк. Стабильные и растворимые составы ингибиторов рецепторных тирозинкиназ и способы их получения
CN110478119B (zh) 2014-11-10 2022-04-15 弗赛特影像4股份有限公司 可膨胀药物递送装置和使用方法
WO2017087902A1 (en) 2015-11-20 2017-05-26 Forsight Vision4, Inc. Porous structures for extended release drug delivery devices
CN113017981B (zh) 2016-04-05 2023-07-25 弗赛特影像4股份有限公司 药物递送装置
CN111655206B (zh) 2017-11-21 2022-10-14 弗赛特影像4股份有限公司 用于可扩展端口递送系统的流体交换装置及使用方法
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
AU2023345389A1 (en) * 2022-09-23 2025-04-17 Madd Ophthalmics Ltd. Mucoadhesive drug delivery systems and methods of use

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6042766B2 (ja) 1978-12-09 1985-09-25 日本化薬株式会社 基剤
GB8524421D0 (en) 1985-10-03 1985-11-06 Boots Co Plc Therapeutic agents
US4853224A (en) * 1987-12-22 1989-08-01 Visionex Biodegradable ocular implants
US4880636A (en) * 1988-05-13 1989-11-14 Franz Robert M Film coated tablet of ranitidine HCl
US4865846A (en) * 1988-06-03 1989-09-12 Kaufman Herbert E Drug delivery system
US6117425A (en) 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
UA34430C2 (uk) 1991-05-13 2001-03-15 Дзе Бутс Компані Плс S(-)-2-(4-ізобутилфеніл)пропіонат натрію дигідрат, придатний для лікування запалення, болю і гіпертермії, фармацевтична композиція на його основі та спосіб одержання s(-)-2-(4-ізобутилфеніл)пропіонату натрію
GB9213077D0 (en) 1992-06-19 1992-08-05 Erba Carlo Spa Polymerbound taxol derivatives
US5614549A (en) 1992-08-21 1997-03-25 Enzon, Inc. High molecular weight polymer-based prodrugs
US5916596A (en) 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US6537579B1 (en) 1993-02-22 2003-03-25 American Bioscience, Inc. Compositions and methods for administration of pharmacologically active compounds
US5362478A (en) 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
US6096331A (en) 1993-02-22 2000-08-01 Vivorx Pharmaceuticals, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US5439686A (en) 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US5665382A (en) 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
NZ262679A (en) 1993-02-22 1997-08-22 Vivorx Pharmaceuticals Inc Compositions for in vivo delivery of pharmaceutical agents where the agents are contained in a polymeric shell
US5886026A (en) 1993-07-19 1999-03-23 Angiotech Pharmaceuticals Inc. Anti-angiogenic compositions and methods of use
TW406020B (en) 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
US5433951A (en) 1993-10-13 1995-07-18 Bristol-Myers Squibb Company Sustained release formulation containing captopril and method
US5484608A (en) * 1994-03-28 1996-01-16 Pharmavene, Inc. Sustained-release drug delivery system
US5626862A (en) 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
US6063116A (en) 1994-10-26 2000-05-16 Medarex, Inc. Modulation of cell proliferation and wound healing
US5783178A (en) 1994-11-18 1998-07-21 Supratek Pharma. Inc. Polymer linked biological agents
US6369116B1 (en) 1995-06-02 2002-04-09 Oculex Pharmaceuticals, Inc. Composition and method for treating glaucoma
RU2086218C1 (ru) 1995-07-26 1997-08-10 Санкт-Петербургская медицинская академия последипломного образования Способ лечения глаукомы
US5736152A (en) 1995-10-27 1998-04-07 Atrix Laboratories, Inc. Non-polymeric sustained release delivery system
FR2748209B1 (fr) * 1996-05-06 1998-06-05 Adir Composition pharmaceutique a base de matrices lipophiles stabilisees pour la liberation controlee de principes actifs
DE69734060T2 (de) 1996-05-24 2006-06-29 Angiotech Pharmaceuticals, Inc., Vancouver Zubereitungen und verfahren zur behandlung oder prävention von krankheiten der körperpassagewege
US5888493A (en) * 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
PT1023050E (pt) 1997-06-27 2013-12-04 Abraxis Bioscience Llc Novas formulações de agentes farmacológicos, métodos para a sua preparação e métodos para a sua utilização
US6004573A (en) 1997-10-03 1999-12-21 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US20020164374A1 (en) 1997-10-29 2002-11-07 John Jackson Polymeric systems for drug delivery and uses thereof
US6146659A (en) 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6017948A (en) 1998-10-30 2000-01-25 Supergen, Inc. Water-miscible pharmaceutical compositions
ES2204531T3 (es) * 1999-03-16 2004-05-01 Merck Patent Gmbh Composicion que comprende isoquercetina y acido ascorbico en una forma de liberacion sostenida.
EP1171117A4 (en) 1999-04-22 2002-08-07 American Bioscience Inc LONG-TERM ADMINISTRATION OF PHARMACOLOGICALLY ACTIVE AGENTS
US6306120B1 (en) 1999-06-07 2001-10-23 Ben Gee Tan Applicator and method for delivery of mitomycin to eye tissues during glaucoma filtering surgery
US6375963B1 (en) * 1999-06-16 2002-04-23 Michael A. Repka Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof
JP2004529934A (ja) * 2001-05-01 2004-09-30 アンジオテック ファーマシューティカルズ,インコーポレイテッド 抗微小管剤およびポリペプチドまたはポリサッカリドを含む組成物、ならびに炎症状態を処置するための医薬品の調製のためのそれらの組成物の使用
US20040058313A1 (en) * 2002-04-24 2004-03-25 Abreu Marcio Marc Compositions, targets, methods and devices for the therapy of ocular and periocular disorders

Also Published As

Publication number Publication date
DK1521572T3 (da) 2009-05-04
CN1668278A (zh) 2005-09-14
CY1109606T1 (el) 2014-08-13
DE60326455D1 (de) 2009-04-16
EP1521572A1 (en) 2005-04-13
JP4454019B2 (ja) 2010-04-21
CA2491312A1 (en) 2004-01-22
WO2004006889A1 (en) 2004-01-22
KR101003514B1 (ko) 2010-12-30
ES2321083T3 (es) 2009-06-02
KR20050025961A (ko) 2005-03-14
ATE424187T1 (de) 2009-03-15
JP2005533106A (ja) 2005-11-04
US20040126408A1 (en) 2004-07-01
PT1521572E (pt) 2009-04-21
CN100500221C (zh) 2009-06-17
EP1521572B1 (en) 2009-03-04
PL374764A1 (en) 2005-10-31
US8084054B2 (en) 2011-12-27
MXPA05000631A (es) 2005-03-31
AU2003247671A1 (en) 2004-02-02
AU2003247671B2 (en) 2008-02-14
PL206379B1 (pl) 2010-08-31
CA2491312C (en) 2011-05-31

Similar Documents

Publication Publication Date Title
PT1521572E (pt) Película bioerodível para administração oftálmica de fármacos
SI1476138T1 (sl) Formulacije s prirejenim sproščanjem vsaj ene oblike tramadola
WO2007081948A3 (en) Bioadhesive drug formulations for oral transmucosal delivery
WO2004009445A3 (en) Packaging and dispensing of rapid dissolve dosage form
HUP0203451A2 (hu) Új, tuberkolózis elleni gyógyszerkészítmények és eljárás előállításukra
MXPA02012792A (es) Composicion y forma de de dosificacion para liberacion gastrica retardada de alendronato y/u otros bis-fosfonatos.
WO2006039336A3 (en) Conveniently implantable sustained release drug compositions
WO1999053910A8 (en) Folic acid-containing pharmaceutical compositions, and related methods and delivery systems
WO2004054542A3 (en) Oral drug delivery system comprising high viscosity liquid carrier materials
AU2003234231A1 (en) New polyarylates for drug delivery and tissue engineering
WO2005063218A3 (en) Pharmaceutical formulations of bisphosphonates
ATE375729T1 (de) Verfahren zur herstellung eines pharmazeutischen kaugummis
AU5680100A (en) Controlled release and taste masking oral pharmaceutical compositions
IL219820A0 (en) Hydrophilic controlled release formulation comprising pregelatinized starch for controlled release of an active component
EA200501819A1 (ru) Способы и фармацевтические композиции для достоверного достижения приемлемых уровней тестостерона в сыворотке
WO2006039692A3 (en) Modified release ibuprofen dosage form
BG108516A (en) Pharmaceutical formulation
AU2003238221A1 (en) Ibuprofen suspension
EP2474307A3 (en) Proliposomal drug delivery system
ATE287264T1 (de) Oral anzuwendende buprenorphinhaltige arzneimittel
HUP0500097A3 (en) Sustained/controlled release solid formulation as a novel drug delivery system with reduced risk of dose dumping
MXPA06000332A (es) Nueva composicion farmaceutica solida que comprende amisulprida.
WO2007086079A3 (en) Sustained release dosage form of phenothiazine derivatives containing channelizer
WO2005065639A3 (en) Novel pharmaceutical compositions
AU2003275006A1 (en) Aerosol drug delivery system employing formulation pre-heating