JP2005529975A - アミドリンカーペルオキシソーム増殖因子活性化受容体調節因子 - Google Patents
アミドリンカーペルオキシソーム増殖因子活性化受容体調節因子 Download PDFInfo
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- JP2005529975A JP2005529975A JP2004515700A JP2004515700A JP2005529975A JP 2005529975 A JP2005529975 A JP 2005529975A JP 2004515700 A JP2004515700 A JP 2004515700A JP 2004515700 A JP2004515700 A JP 2004515700A JP 2005529975 A JP2005529975 A JP 2005529975A
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- Prior art keywords
- phenyl
- ethoxy
- alkyl
- propionic acid
- aryl
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- 0 CC(C)(*)C(CC1)CCC1NC(C(C)(*)Oc1ccc(CC(**)C(O)=O)cc1)=O Chemical compound CC(C)(*)C(CC1)CCC1NC(C(C)(*)Oc1ccc(CC(**)C(O)=O)cc1)=O 0.000 description 9
- PLYYWFFKENXVDZ-QFIPXVFZSA-N CCO[C@@H](Cc(cc1)ccc1OC(C)(C)C(NCCc(cc(cc1)Cl)c1[I](C)C)=O)C(O)=O Chemical compound CCO[C@@H](Cc(cc1)ccc1OC(C)(C)C(NCCc(cc(cc1)Cl)c1[I](C)C)=O)C(O)=O PLYYWFFKENXVDZ-QFIPXVFZSA-N 0.000 description 2
- FVBMCHRHQIIJCH-UHFFFAOYSA-N C/[O]=C/C(Cc(cc1)ccc1OCC(N(CC1)CCN1c1ccc(C(F)(F)[F]C[IH]C)cc1)=O)C(O)=O Chemical compound C/[O]=C/C(Cc(cc1)ccc1OCC(N(CC1)CCN1c1ccc(C(F)(F)[F]C[IH]C)cc1)=O)C(O)=O FVBMCHRHQIIJCH-UHFFFAOYSA-N 0.000 description 1
- HRTUGERFTIEFBH-UHFFFAOYSA-N CC(C([I](CC1)CCC1O)=O)(N)[IH]c1ccccc1 Chemical compound CC(C([I](CC1)CCC1O)=O)(N)[IH]c1ccccc1 HRTUGERFTIEFBH-UHFFFAOYSA-N 0.000 description 1
- ZOGUTDIFRPDUPU-VWLOTQADSA-N CC(C)(C(NCCc(cc1)ccc1Oc1ccccc1)=O)Oc1ccc(C[C@@H](C(O)=O)OC)cc1 Chemical compound CC(C)(C(NCCc(cc1)ccc1Oc1ccccc1)=O)Oc1ccc(C[C@@H](C(O)=O)OC)cc1 ZOGUTDIFRPDUPU-VWLOTQADSA-N 0.000 description 1
- BEEBGXKSMANYFX-DEOSSOPVSA-N CC(C)(C(NCc1cccc(-c2ccccc2)c1)=O)Oc1ccc(C[C@@H](C(O)=O)OC)cc1 Chemical compound CC(C)(C(NCc1cccc(-c2ccccc2)c1)=O)Oc1ccc(C[C@@H](C(O)=O)OC)cc1 BEEBGXKSMANYFX-DEOSSOPVSA-N 0.000 description 1
- OUQZFXLHBLJIGG-UHFFFAOYSA-N CCCCCCCCNC(C(C)(C)Oc1ccc(C/C(/C(O)=O)=[O]\C)cc1)=O Chemical compound CCCCCCCCNC(C(C)(C)Oc1ccc(C/C(/C(O)=O)=[O]\C)cc1)=O OUQZFXLHBLJIGG-UHFFFAOYSA-N 0.000 description 1
- VGOILMCHXIELBT-FCHUYYIVSA-N CCCO[C@@H](Cc(cc1)ccc1O[C@H](CI)C(OCc1ccccc1)=O)C(OCC)=O Chemical compound CCCO[C@@H](Cc(cc1)ccc1O[C@H](CI)C(OCc1ccccc1)=O)C(OCC)=O VGOILMCHXIELBT-FCHUYYIVSA-N 0.000 description 1
- YFPCYBNGQSABIR-UHFFFAOYSA-N CCOC(/C(/Cc(cc1)ccc1OCC(O)=O)=[O]\C)=O Chemical compound CCOC(/C(/Cc(cc1)ccc1OCC(O)=O)=[O]\C)=O YFPCYBNGQSABIR-UHFFFAOYSA-N 0.000 description 1
- RTSOWOJQZPYDAK-UHFFFAOYSA-N CCOC(Cc(cc1)ccc1OC(C)C(O)PCc1ccccc1)C(OCC)=O Chemical compound CCOC(Cc(cc1)ccc1OC(C)C(O)PCc1ccccc1)C(OCC)=O RTSOWOJQZPYDAK-UHFFFAOYSA-N 0.000 description 1
- GZLGDCYADWAJOP-BJQOMGFOSA-N CCOC(Cc(cc1)ccc1O[C@@H](C)C(NCCc1cc(C(F)(F)[I]=C)ccc1)=O)C(O)=O Chemical compound CCOC(Cc(cc1)ccc1O[C@@H](C)C(NCCc1cc(C(F)(F)[I]=C)ccc1)=O)C(O)=O GZLGDCYADWAJOP-BJQOMGFOSA-N 0.000 description 1
- XQCGLUWPEOIXNC-UBDBMELISA-N CCOC(Cc(cc1)ccc1O[C@@H](C)C(NCc1cc(-c2ccccc2)ccc1)=O)C(O)=O Chemical compound CCOC(Cc(cc1)ccc1O[C@@H](C)C(NCc1cc(-c2ccccc2)ccc1)=O)C(O)=O XQCGLUWPEOIXNC-UBDBMELISA-N 0.000 description 1
- XSYXBYXPKMFDIU-YJYMSZOUSA-N CCO[C@@H](Cc(cc1)ccc1O[C@H](C)C(NCc1cc(F)cc(C(F)(F)F)c1)=O)C(O)=O Chemical compound CCO[C@@H](Cc(cc1)ccc1O[C@H](C)C(NCc1cc(F)cc(C(F)(F)F)c1)=O)C(O)=O XSYXBYXPKMFDIU-YJYMSZOUSA-N 0.000 description 1
- SJPPTTVDLNFCNP-NRFANRHFSA-N CCOc1c(CCNC(C(C)(C)Oc2ccc(C[C@@H](C(O)=O)OC)cc2)=O)cccc1 Chemical compound CCOc1c(CCNC(C(C)(C)Oc2ccc(C[C@@H](C(O)=O)OC)cc2)=O)cccc1 SJPPTTVDLNFCNP-NRFANRHFSA-N 0.000 description 1
- BZQIZKKSIIOBHX-UHFFFAOYSA-N CCc1ccc(CCNC(COc2cccc(CC(C(C3)C3O)C(O)=O)c2)=O)cc1 Chemical compound CCc1ccc(CCNC(COc2cccc(CC(C(C3)C3O)C(O)=O)c2)=O)cc1 BZQIZKKSIIOBHX-UHFFFAOYSA-N 0.000 description 1
- PCENEWKKNFQGCC-PIVQAISJSA-N CN1N=C(C2CC2)SC1NC(COc1ccc(C[C@@H](C(O)=O)OC)cc1)=O Chemical compound CN1N=C(C2CC2)SC1NC(COc1ccc(C[C@@H](C(O)=O)OC)cc1)=O PCENEWKKNFQGCC-PIVQAISJSA-N 0.000 description 1
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- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
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- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
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- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
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- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
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- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
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- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
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- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
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- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
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- C—CHEMISTRY; METALLURGY
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- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
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- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C—CHEMISTRY; METALLURGY
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- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
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Applications Claiming Priority (2)
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| US39010202P | 2002-06-19 | 2002-06-19 | |
| PCT/US2003/016207 WO2004000789A1 (en) | 2002-06-19 | 2003-06-11 | Amide linker peroxisome proliferator activated receptor modulators |
Publications (2)
| Publication Number | Publication Date |
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| JP2005529975A true JP2005529975A (ja) | 2005-10-06 |
| JP2005529975A5 JP2005529975A5 (cg-RX-API-DMAC7.html) | 2006-07-27 |
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| EP (1) | EP1517882A1 (cg-RX-API-DMAC7.html) |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006045240A (ja) * | 2002-12-21 | 2006-02-16 | Astrazeneca Ab | 治療薬剤 |
| JP2007516267A (ja) * | 2003-12-15 | 2007-06-21 | イーライ リリー アンド カンパニー | 選択的ペルオキシソーム増殖因子活性化受容体モジュレータ |
| JP2008239616A (ja) * | 2007-02-28 | 2008-10-09 | Iyaku Bunshi Sekkei Kenkyusho:Kk | Hdl上昇剤 |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
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| SE0104334D0 (sv) * | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| GB0314079D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0405033D0 (en) * | 2004-03-05 | 2004-04-07 | Karobio Ab | Novel pharmaceutical compositions |
| US8071624B2 (en) | 2004-06-24 | 2011-12-06 | Incyte Corporation | N-substituted piperidines and their use as pharmaceuticals |
| CA2584502A1 (en) * | 2004-06-24 | 2006-01-05 | Incyte Corporation | 2-methylpropanamides and their use as pharmaceuticals |
| GT200500375A (es) * | 2004-12-20 | 2006-11-28 | Derivados de piperidina y su uso como agentes antiinflamatorios | |
| EP1893583B1 (en) | 2005-05-31 | 2012-04-04 | Pfizer Inc. | Substituted aryloxy-n-bicyclomethyl acetamide compounds as vr1 antagonists |
| US8097610B2 (en) * | 2005-08-26 | 2012-01-17 | Shionogi & Co., Ltd. | Derivative having PPAR agonistic activity |
| CN107382980B (zh) * | 2016-05-14 | 2020-05-15 | 湖南大学 | N-[(二氢苯并呋喃-7-氧基)烷基]-2-芳氧基酰胺衍生物 |
| EP3689324B1 (de) * | 2019-02-04 | 2024-11-20 | Symrise AG | Neue kühlstoffe und zubereitungen, die diese enthalten |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3889545T2 (de) | 1987-10-20 | 1994-10-13 | Otsuka Pharma Co Ltd | Phenylcarbonsäure-abkömmlinge. |
| US5122539A (en) | 1990-02-12 | 1992-06-16 | Center For Innovative Technology | Allosteric hemoglobin modifiers useful for decreasing oxygen affinity and preserving oxygen carrying capability of stored blood |
| GB9027023D0 (en) | 1990-12-12 | 1991-01-30 | Wellcome Found | Anti-atherosclerotic aryl compounds |
| CA2090283A1 (en) | 1992-02-28 | 1993-08-29 | Nobuyuki Hamanaka | Phenoxyacetic acid derivatives |
| JP3144624B2 (ja) | 1995-06-02 | 2001-03-12 | 杏林製薬株式会社 | N−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
| AU721452B2 (en) | 1996-02-02 | 2000-07-06 | Merck & Co., Inc. | Antidiabetic agents |
| EP1019364B1 (en) | 1997-08-28 | 2004-06-09 | Biovitrum Ab | Inhibitors of protein tyrosine phosphatase |
| AU3958200A (en) * | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6417212B1 (en) | 1999-08-27 | 2002-07-09 | Eli Lilly & Company | Modulators of peroxisome proliferator activated receptors |
| PE20011010A1 (es) | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| JP2001261612A (ja) * | 2000-03-22 | 2001-09-26 | Mitsui Chemicals Inc | カテコールプロピオン酸誘導体およびそれを有効成分として含有する核内レセプター作動薬 |
| EP1310494B1 (en) | 2000-08-11 | 2012-01-25 | Nippon Chemiphar Co., Ltd. | PPAR (delta) ACTIVATORS |
| UA82048C2 (uk) | 2000-11-10 | 2008-03-11 | Эли Лилли Энд Компани | Агоністи альфа-рецепторів, активованих проліфератором пероксисом |
| GB0113232D0 (en) | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical process |
| CN1582279A (zh) | 2001-11-30 | 2005-02-16 | 伊莱利利公司 | 过氧化物酶体激活的受体激动剂 |
| SE0104334D0 (sv) * | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| DE60327922D1 (de) | 2002-02-05 | 2009-07-23 | Lilly Co Eli | Harnstoff-linker verbindungen und ihre verwendung als ppar regulatoren |
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2003
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- 2003-06-11 WO PCT/US2003/016207 patent/WO2004000789A1/en not_active Ceased
- 2003-06-11 MX MXPA04013000A patent/MXPA04013000A/es active IP Right Grant
- 2003-06-11 US US10/517,581 patent/US7220880B2/en not_active Expired - Fee Related
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- 2003-06-17 AR ARP030102136A patent/AR039684A1/es unknown
- 2003-06-18 PE PE2003000616A patent/PE20040580A1/es not_active Application Discontinuation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006045240A (ja) * | 2002-12-21 | 2006-02-16 | Astrazeneca Ab | 治療薬剤 |
| JP2007516267A (ja) * | 2003-12-15 | 2007-06-21 | イーライ リリー アンド カンパニー | 選択的ペルオキシソーム増殖因子活性化受容体モジュレータ |
| JP2008239616A (ja) * | 2007-02-28 | 2008-10-09 | Iyaku Bunshi Sekkei Kenkyusho:Kk | Hdl上昇剤 |
Also Published As
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|---|---|
| WO2004000789A9 (en) | 2004-03-11 |
| BR0311834A (pt) | 2005-04-12 |
| AR039684A1 (es) | 2005-03-09 |
| AU2003241579B2 (en) | 2009-03-19 |
| WO2004000789A1 (en) | 2003-12-31 |
| US7220880B2 (en) | 2007-05-22 |
| AU2003241579A1 (en) | 2004-01-06 |
| TW200406371A (en) | 2004-05-01 |
| MXPA04013000A (es) | 2005-09-12 |
| EP1517882A1 (en) | 2005-03-30 |
| CA2488972A1 (en) | 2003-12-31 |
| AU2003241579B9 (en) | 2009-07-30 |
| CN1662487A (zh) | 2005-08-31 |
| PE20040580A1 (es) | 2004-09-08 |
| US20060111406A1 (en) | 2006-05-25 |
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