JP2005526073A5 - - Google Patents
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- Publication number
- JP2005526073A5 JP2005526073A5 JP2003574662A JP2003574662A JP2005526073A5 JP 2005526073 A5 JP2005526073 A5 JP 2005526073A5 JP 2003574662 A JP2003574662 A JP 2003574662A JP 2003574662 A JP2003574662 A JP 2003574662A JP 2005526073 A5 JP2005526073 A5 JP 2005526073A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- compound
- hydrogen atom
- atom
- alkynyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 6
- 125000003342 alkenyl group Chemical group 0.000 claims 5
- 125000000304 alkynyl group Chemical group 0.000 claims 5
- 125000003710 aryl alkyl group Chemical group 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 5
- 125000000753 cycloalkyl group Chemical group 0.000 claims 5
- 125000000547 substituted alkyl group Chemical group 0.000 claims 5
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000012453 solvate Substances 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 125000004434 sulfur atom Chemical group 0.000 claims 2
- 208000030852 Parasitic disease Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical class C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 230000002140 halogenating effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 125000003375 sulfoxide group Chemical group 0.000 claims 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02005233 | 2002-03-08 | ||
| PCT/EP2003/001839 WO2003076446A1 (en) | 2002-03-08 | 2003-02-24 | Antiparasitic artemisinin derivatives (endoperoxides) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005526073A JP2005526073A (ja) | 2005-09-02 |
| JP2005526073A5 true JP2005526073A5 (enExample) | 2006-04-13 |
Family
ID=27798779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003574662A Pending JP2005526073A (ja) | 2002-03-08 | 2003-02-24 | 駆虫性アルテミシニン誘導体（エンドペルオキシド類） |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20050119232A1 (enExample) |
| EP (1) | EP1485389B1 (enExample) |
| JP (1) | JP2005526073A (enExample) |
| KR (1) | KR20040104493A (enExample) |
| CN (1) | CN1649874A (enExample) |
| AR (1) | AR038842A1 (enExample) |
| AT (1) | ATE334987T1 (enExample) |
| AU (1) | AU2003215584A1 (enExample) |
| BR (1) | BR0308291A (enExample) |
| CA (1) | CA2478600A1 (enExample) |
| DE (1) | DE60307239D1 (enExample) |
| HR (1) | HRP20040927A2 (enExample) |
| IL (1) | IL163870A0 (enExample) |
| MX (1) | MXPA04008638A (enExample) |
| NZ (1) | NZ535084A (enExample) |
| PL (1) | PL372341A1 (enExample) |
| RU (1) | RU2004130284A (enExample) |
| TW (1) | TW200400964A (enExample) |
| WO (1) | WO2003076446A1 (enExample) |
| YU (1) | YU79304A (enExample) |
| ZA (1) | ZA200407102B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004027871B3 (de) * | 2004-06-08 | 2006-03-16 | Lanxess Deutschland Gmbh | Verfahren zur Herstellung von 10α-[4'-(S,S-Dioxothiomorpholin-1'-yl)]-10-desoxo-10-dihydroartemisinin |
| EP1714967A1 (en) * | 2005-04-22 | 2006-10-25 | Bayer HealthCare AG | Antiparasitic artemisinin derivatives |
| PT1940383E (pt) * | 2005-10-20 | 2011-09-14 | Epipharm Gmbh | Tratamento e prevenção de sinais pigmentados benignos (nevos) utilizando artemisinina e os seus derivados |
| US8431611B2 (en) | 2006-10-20 | 2013-04-30 | Johns Hopkins University | Artemisinin derivatives |
| WO2009062939A1 (en) * | 2007-11-15 | 2009-05-22 | Novartis Ag | Anthelmintic paste comprising praziquantel, a macrolide lactone, cyclodextrin and a thickener |
| US8815942B2 (en) | 2010-10-20 | 2014-08-26 | The Royal Institution For The Advancement Of Learning/Mcgill University | Combination therapy and uses thereof for treatment and prevention of parasitic infection and disease |
| CN102010422B (zh) * | 2010-11-23 | 2014-11-26 | 沈阳药科大学 | 含有胍基的青蒿素类衍生物及其应用 |
| US8232417B1 (en) | 2010-12-01 | 2012-07-31 | Bioderm Research | Artemisinin derivatives with natural amino acids, peptides, and amino sugars for skin imperfections and infection in mammals |
| CN103183682B (zh) * | 2011-12-31 | 2015-10-14 | 沈阳药科大学 | C-10位脲基取代的青蒿素衍生物及其制备方法和用途 |
| BR112014026158A2 (pt) * | 2012-04-18 | 2017-06-27 | Hadasit Med Res Service | métodos e composições para o tratamento de infecções virais |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5726203A (en) * | 1993-07-19 | 1998-03-10 | Li; Zelin | Qinghaosu derivatives against AIDS |
| EP0974594A1 (en) * | 1998-07-14 | 2000-01-26 | The Hong Kong University of Science & Technology | Artemisinin derivatives as anti-infective agent |
| BR9912810A (pt) * | 1998-07-14 | 2001-05-02 | Bayer Ag | Derivados artemisinina (endoperóxidos) antiparasìticos |
-
2003
- 2003-02-24 WO PCT/EP2003/001839 patent/WO2003076446A1/en not_active Ceased
- 2003-02-24 DE DE60307239T patent/DE60307239D1/de not_active Expired - Lifetime
- 2003-02-24 HR HR20040927A patent/HRP20040927A2/hr not_active Application Discontinuation
- 2003-02-24 CA CA002478600A patent/CA2478600A1/en not_active Abandoned
- 2003-02-24 EP EP03743815A patent/EP1485389B1/en not_active Expired - Lifetime
- 2003-02-24 IL IL16387003A patent/IL163870A0/xx unknown
- 2003-02-24 BR BR0308291-1A patent/BR0308291A/pt not_active IP Right Cessation
- 2003-02-24 AU AU2003215584A patent/AU2003215584A1/en not_active Abandoned
- 2003-02-24 NZ NZ535084A patent/NZ535084A/en unknown
- 2003-02-24 MX MXPA04008638A patent/MXPA04008638A/es unknown
- 2003-02-24 KR KR10-2004-7013999A patent/KR20040104493A/ko not_active Withdrawn
- 2003-02-24 YU YU79304A patent/YU79304A/sh unknown
- 2003-02-24 RU RU2004130284/04A patent/RU2004130284A/ru not_active Application Discontinuation
- 2003-02-24 AT AT03743815T patent/ATE334987T1/de not_active IP Right Cessation
- 2003-02-24 US US10/506,926 patent/US20050119232A1/en not_active Abandoned
- 2003-02-24 JP JP2003574662A patent/JP2005526073A/ja active Pending
- 2003-02-24 PL PL03372341A patent/PL372341A1/xx not_active Application Discontinuation
- 2003-02-24 CN CNA038095998A patent/CN1649874A/zh active Pending
- 2003-02-26 AR ARP030100629A patent/AR038842A1/es unknown
- 2003-03-07 TW TW092104875A patent/TW200400964A/zh unknown
-
2004
- 2004-09-06 ZA ZA200407102A patent/ZA200407102B/en unknown
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