DE60307239D1 - Artemisininderivate (endoperoxide) mit wirkung gegen parasiten - Google Patents

Artemisininderivate (endoperoxide) mit wirkung gegen parasiten

Info

Publication number
DE60307239D1
DE60307239D1 DE60307239T DE60307239T DE60307239D1 DE 60307239 D1 DE60307239 D1 DE 60307239D1 DE 60307239 T DE60307239 T DE 60307239T DE 60307239 T DE60307239 T DE 60307239T DE 60307239 D1 DE60307239 D1 DE 60307239D1
Authority
DE
Germany
Prior art keywords
endoperoxides
effect against
against parasites
artemisinine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60307239T
Other languages
English (en)
Inventor
Hong Kong Univ Scien Te Haynes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Application granted granted Critical
Publication of DE60307239D1 publication Critical patent/DE60307239D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems
DE60307239T 2002-03-08 2003-02-24 Artemisininderivate (endoperoxide) mit wirkung gegen parasiten Expired - Lifetime DE60307239D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02005233 2002-03-08
PCT/EP2003/001839 WO2003076446A1 (en) 2002-03-08 2003-02-24 Antiparasitic artemisinin derivatives (endoperoxides)

Publications (1)

Publication Number Publication Date
DE60307239D1 true DE60307239D1 (de) 2006-09-14

Family

ID=27798779

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60307239T Expired - Lifetime DE60307239D1 (de) 2002-03-08 2003-02-24 Artemisininderivate (endoperoxide) mit wirkung gegen parasiten

Country Status (21)

Country Link
US (1) US20050119232A1 (de)
EP (1) EP1485389B1 (de)
JP (1) JP2005526073A (de)
KR (1) KR20040104493A (de)
CN (1) CN1649874A (de)
AR (1) AR038842A1 (de)
AT (1) ATE334987T1 (de)
AU (1) AU2003215584A1 (de)
BR (1) BR0308291A (de)
CA (1) CA2478600A1 (de)
DE (1) DE60307239D1 (de)
HR (1) HRP20040927A2 (de)
IL (1) IL163870A0 (de)
MX (1) MXPA04008638A (de)
NZ (1) NZ535084A (de)
PL (1) PL372341A1 (de)
RU (1) RU2004130284A (de)
TW (1) TW200400964A (de)
WO (1) WO2003076446A1 (de)
YU (1) YU79304A (de)
ZA (1) ZA200407102B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004027871B3 (de) * 2004-06-08 2006-03-16 Lanxess Deutschland Gmbh Verfahren zur Herstellung von 10α-[4'-(S,S-Dioxothiomorpholin-1'-yl)]-10-desoxo-10-dihydroartemisinin
EP1714967A1 (de) * 2005-04-22 2006-10-25 Bayer HealthCare AG Antiparasitär wirkende Artemisinin Derivate
US8013011B2 (en) * 2005-10-20 2011-09-06 Epipharm Gmbh Treatment and prevention of benign pigmented moles (naevi) using artemisinine and the derivatives thereof
WO2008127381A2 (en) * 2006-10-20 2008-10-23 Johns Hopkins University Artemisinin derivatives
WO2009062939A1 (en) * 2007-11-15 2009-05-22 Novartis Ag Anthelmintic paste comprising praziquantel, a macrolide lactone, cyclodextrin and a thickener
US8815942B2 (en) 2010-10-20 2014-08-26 The Royal Institution For The Advancement Of Learning/Mcgill University Combination therapy and uses thereof for treatment and prevention of parasitic infection and disease
CN102010422B (zh) * 2010-11-23 2014-11-26 沈阳药科大学 含有胍基的青蒿素类衍生物及其应用
US8232417B1 (en) 2010-12-01 2012-07-31 Bioderm Research Artemisinin derivatives with natural amino acids, peptides, and amino sugars for skin imperfections and infection in mammals
CN103183682B (zh) * 2011-12-31 2015-10-14 沈阳药科大学 C-10位脲基取代的青蒿素衍生物及其制备方法和用途
US9616067B2 (en) 2012-04-18 2017-04-11 Hadasit Medical Research Services And Development Ltd. Methods and compositions for treating viral infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726203A (en) * 1993-07-19 1998-03-10 Li; Zelin Qinghaosu derivatives against AIDS
RU2236413C2 (ru) * 1998-07-14 2004-09-20 Байер Акциенгезельшафт Производные артемизинина, способ их получения, фармацевтическая композиция на их основе и способ лечения
EP0974594A1 (de) * 1998-07-14 2000-01-26 The Hong Kong University of Science & Technology Artemisininderivate als Mittel gegen Infektionen

Also Published As

Publication number Publication date
HRP20040927A2 (en) 2005-06-30
ZA200407102B (en) 2005-09-06
IL163870A0 (en) 2005-12-18
CA2478600A1 (en) 2003-09-18
RU2004130284A (ru) 2005-05-10
EP1485389B1 (de) 2006-08-02
JP2005526073A (ja) 2005-09-02
AU2003215584A1 (en) 2003-09-22
WO2003076446A1 (en) 2003-09-18
AR038842A1 (es) 2005-01-26
YU79304A (sh) 2006-08-17
TW200400964A (en) 2004-01-16
EP1485389A1 (de) 2004-12-15
ATE334987T1 (de) 2006-08-15
MXPA04008638A (es) 2005-04-19
PL372341A1 (en) 2005-07-11
BR0308291A (pt) 2005-01-11
WO2003076446A8 (en) 2004-10-07
CN1649874A (zh) 2005-08-03
KR20040104493A (ko) 2004-12-10
NZ535084A (en) 2006-05-26
US20050119232A1 (en) 2005-06-02

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Legal Events

Date Code Title Description
8332 No legal effect for de