DE60307239D1 - Artemisininderivate (endoperoxide) mit wirkung gegen parasiten - Google Patents
Artemisininderivate (endoperoxide) mit wirkung gegen parasitenInfo
- Publication number
- DE60307239D1 DE60307239D1 DE60307239T DE60307239T DE60307239D1 DE 60307239 D1 DE60307239 D1 DE 60307239D1 DE 60307239 T DE60307239 T DE 60307239T DE 60307239 T DE60307239 T DE 60307239T DE 60307239 D1 DE60307239 D1 DE 60307239D1
- Authority
- DE
- Germany
- Prior art keywords
- endoperoxides
- effect against
- against parasites
- artemisinine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical class C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 title 1
- 244000045947 parasite Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/20—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02005233 | 2002-03-08 | ||
| PCT/EP2003/001839 WO2003076446A1 (en) | 2002-03-08 | 2003-02-24 | Antiparasitic artemisinin derivatives (endoperoxides) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60307239D1 true DE60307239D1 (de) | 2006-09-14 |
Family
ID=27798779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60307239T Expired - Lifetime DE60307239D1 (de) | 2002-03-08 | 2003-02-24 | Artemisininderivate (endoperoxide) mit wirkung gegen parasiten |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20050119232A1 (enExample) |
| EP (1) | EP1485389B1 (enExample) |
| JP (1) | JP2005526073A (enExample) |
| KR (1) | KR20040104493A (enExample) |
| CN (1) | CN1649874A (enExample) |
| AR (1) | AR038842A1 (enExample) |
| AT (1) | ATE334987T1 (enExample) |
| AU (1) | AU2003215584A1 (enExample) |
| BR (1) | BR0308291A (enExample) |
| CA (1) | CA2478600A1 (enExample) |
| DE (1) | DE60307239D1 (enExample) |
| HR (1) | HRP20040927A2 (enExample) |
| IL (1) | IL163870A0 (enExample) |
| MX (1) | MXPA04008638A (enExample) |
| NZ (1) | NZ535084A (enExample) |
| PL (1) | PL372341A1 (enExample) |
| RU (1) | RU2004130284A (enExample) |
| TW (1) | TW200400964A (enExample) |
| WO (1) | WO2003076446A1 (enExample) |
| YU (1) | YU79304A (enExample) |
| ZA (1) | ZA200407102B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004027871B3 (de) * | 2004-06-08 | 2006-03-16 | Lanxess Deutschland Gmbh | Verfahren zur Herstellung von 10α-[4'-(S,S-Dioxothiomorpholin-1'-yl)]-10-desoxo-10-dihydroartemisinin |
| EP1714967A1 (en) * | 2005-04-22 | 2006-10-25 | Bayer HealthCare AG | Antiparasitic artemisinin derivatives |
| AU2006303809B2 (en) * | 2005-10-20 | 2012-11-15 | Epipharm Ag | Treatment and prevention of benign pigmented moles (naevi) using artemisinine and the derivatives thereof |
| WO2008127381A2 (en) * | 2006-10-20 | 2008-10-23 | Johns Hopkins University | Artemisinin derivatives |
| CA2703008A1 (en) * | 2007-11-15 | 2009-05-22 | Novartis Ag | Anthelmintic paste comprising praziquantel, a macrolide lactone, cyclodextrin and a thickener |
| US8815942B2 (en) | 2010-10-20 | 2014-08-26 | The Royal Institution For The Advancement Of Learning/Mcgill University | Combination therapy and uses thereof for treatment and prevention of parasitic infection and disease |
| CN102010422B (zh) * | 2010-11-23 | 2014-11-26 | 沈阳药科大学 | 含有胍基的青蒿素类衍生物及其应用 |
| US8232417B1 (en) | 2010-12-01 | 2012-07-31 | Bioderm Research | Artemisinin derivatives with natural amino acids, peptides, and amino sugars for skin imperfections and infection in mammals |
| CN103183682B (zh) * | 2011-12-31 | 2015-10-14 | 沈阳药科大学 | C-10位脲基取代的青蒿素衍生物及其制备方法和用途 |
| US9616067B2 (en) | 2012-04-18 | 2017-04-11 | Hadasit Medical Research Services And Development Ltd. | Methods and compositions for treating viral infections |
| CN121311595A (zh) | 2023-04-17 | 2026-01-09 | 阿斯克生物公司 | 转基因在灵长类动物中可调节的受控表达 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0713877A1 (en) * | 1993-07-19 | 1996-05-29 | LUO, Xuande | Qinghaosu derivatives against aids |
| EP0974594A1 (en) * | 1998-07-14 | 2000-01-26 | The Hong Kong University of Science & Technology | Artemisinin derivatives as anti-infective agent |
| NZ509324A (en) * | 1998-07-14 | 2003-07-25 | Bayer Ag | Antiparasitic artemisinin derivatives (endoperoxides) |
-
2003
- 2003-02-24 AU AU2003215584A patent/AU2003215584A1/en not_active Abandoned
- 2003-02-24 IL IL16387003A patent/IL163870A0/xx unknown
- 2003-02-24 AT AT03743815T patent/ATE334987T1/de not_active IP Right Cessation
- 2003-02-24 YU YU79304A patent/YU79304A/sh unknown
- 2003-02-24 PL PL03372341A patent/PL372341A1/xx not_active Application Discontinuation
- 2003-02-24 CN CNA038095998A patent/CN1649874A/zh active Pending
- 2003-02-24 MX MXPA04008638A patent/MXPA04008638A/es unknown
- 2003-02-24 CA CA002478600A patent/CA2478600A1/en not_active Abandoned
- 2003-02-24 RU RU2004130284/04A patent/RU2004130284A/ru not_active Application Discontinuation
- 2003-02-24 JP JP2003574662A patent/JP2005526073A/ja active Pending
- 2003-02-24 WO PCT/EP2003/001839 patent/WO2003076446A1/en not_active Ceased
- 2003-02-24 BR BR0308291-1A patent/BR0308291A/pt not_active IP Right Cessation
- 2003-02-24 US US10/506,926 patent/US20050119232A1/en not_active Abandoned
- 2003-02-24 HR HR20040927A patent/HRP20040927A2/hr not_active Application Discontinuation
- 2003-02-24 NZ NZ535084A patent/NZ535084A/en unknown
- 2003-02-24 EP EP03743815A patent/EP1485389B1/en not_active Expired - Lifetime
- 2003-02-24 KR KR10-2004-7013999A patent/KR20040104493A/ko not_active Withdrawn
- 2003-02-24 DE DE60307239T patent/DE60307239D1/de not_active Expired - Lifetime
- 2003-02-26 AR ARP030100629A patent/AR038842A1/es unknown
- 2003-03-07 TW TW092104875A patent/TW200400964A/zh unknown
-
2004
- 2004-09-06 ZA ZA200407102A patent/ZA200407102B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200400964A (en) | 2004-01-16 |
| CN1649874A (zh) | 2005-08-03 |
| WO2003076446A1 (en) | 2003-09-18 |
| NZ535084A (en) | 2006-05-26 |
| JP2005526073A (ja) | 2005-09-02 |
| BR0308291A (pt) | 2005-01-11 |
| AU2003215584A1 (en) | 2003-09-22 |
| WO2003076446A8 (en) | 2004-10-07 |
| YU79304A (sh) | 2006-08-17 |
| ATE334987T1 (de) | 2006-08-15 |
| KR20040104493A (ko) | 2004-12-10 |
| PL372341A1 (en) | 2005-07-11 |
| IL163870A0 (en) | 2005-12-18 |
| CA2478600A1 (en) | 2003-09-18 |
| ZA200407102B (en) | 2005-09-06 |
| MXPA04008638A (es) | 2005-04-19 |
| HRP20040927A2 (en) | 2005-06-30 |
| RU2004130284A (ru) | 2005-05-10 |
| EP1485389B1 (en) | 2006-08-02 |
| EP1485389A1 (en) | 2004-12-15 |
| AR038842A1 (es) | 2005-01-26 |
| US20050119232A1 (en) | 2005-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |