JP2005517672A5 - - Google Patents

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Publication number
JP2005517672A5
JP2005517672A5 JP2003556062A JP2003556062A JP2005517672A5 JP 2005517672 A5 JP2005517672 A5 JP 2005517672A5 JP 2003556062 A JP2003556062 A JP 2003556062A JP 2003556062 A JP2003556062 A JP 2003556062A JP 2005517672 A5 JP2005517672 A5 JP 2005517672A5
Authority
JP
Japan
Prior art keywords
urea
methyl
phenyl
trifluoromethyl
benzothiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2003556062A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005517672A (ja
Filing date
Publication date
Priority claimed from JP2001395031A external-priority patent/JP2003192587A/ja
Application filed filed Critical
Publication of JP2005517672A publication Critical patent/JP2005517672A/ja
Publication of JP2005517672A5 publication Critical patent/JP2005517672A5/ja
Withdrawn legal-status Critical Current

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JP2003556062A 2001-12-26 2002-12-13 尿素誘導体 Withdrawn JP2005517672A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001395031A JP2003192587A (ja) 2001-12-26 2001-12-26 尿素誘導体
PCT/EP2002/014215 WO2003055484A1 (en) 2001-12-26 2002-12-13 Urea derivatives

Publications (2)

Publication Number Publication Date
JP2005517672A JP2005517672A (ja) 2005-06-16
JP2005517672A5 true JP2005517672A5 (https=) 2006-02-02

Family

ID=19188927

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001395031A Pending JP2003192587A (ja) 2001-12-26 2001-12-26 尿素誘導体
JP2003556062A Withdrawn JP2005517672A (ja) 2001-12-26 2002-12-13 尿素誘導体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2001395031A Pending JP2003192587A (ja) 2001-12-26 2001-12-26 尿素誘導体

Country Status (6)

Country Link
US (1) US20050119304A1 (https=)
EP (1) EP1465623A1 (https=)
JP (2) JP2003192587A (https=)
AU (1) AU2002367186A1 (https=)
CA (1) CA2471236A1 (https=)
WO (1) WO2003055484A1 (https=)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE420644T1 (de) * 2002-02-20 2009-01-15 Abbott Lab Kondensierte azabicyclischeverbindungen als inhibitoren des vanilloid-rezeptors 1 (vr1)
US7074805B2 (en) * 2002-02-20 2006-07-11 Abbott Laboratories Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
MXPA05002493A (es) * 2002-09-05 2005-05-27 Neurosearch As Derivados de diarilurea y su uso como bloqueadores del canal del cloro.
WO2004028440A2 (en) * 2002-09-24 2004-04-08 Bayer Healthcare Ag Vr1 antagonists for the treatment of urological disorders
US7015233B2 (en) 2003-06-12 2006-03-21 Abbott Laboratories Fused compounds that inhibit vanilloid subtype 1 (VR1) receptor
US7375126B2 (en) 2003-06-12 2008-05-20 Abbott Laboratories Fused compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
PT2017265E (pt) * 2003-06-12 2011-07-29 Abbott Lab Compostos condensados que inibem o receptor vanilóide de subtipo 1 (vr1)
GB0322016D0 (en) * 2003-09-19 2003-10-22 Merck Sharp & Dohme New compounds
JP4935073B2 (ja) 2003-10-14 2012-05-23 味の素株式会社 エーテル誘導体
EP1685112B1 (en) * 2003-11-08 2011-07-20 Bayer Schering Pharma Aktiengesellschaft Tetrahydro-quinolinylurea derivatives as vr1 antagonists
GB0326633D0 (en) * 2003-11-14 2003-12-17 Merck Sharp & Dohme Therapeutic agents
US7550499B2 (en) 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
JP2008515884A (ja) * 2004-10-08 2008-05-15 アストラゼネカ・アクチエボラーグ 新規なヒドロキシメチルベンゾチアゾールアミド
SE0403118D0 (sv) * 2004-12-21 2004-12-21 Astrazeneca Ab New compounds 2
EP1954696B1 (en) * 2005-01-19 2011-02-23 Bristol-Myers Squibb Company 2-phenoxy-n-(1,3,4-thiadizol-2-yl)pyridin-3-amine derivatives and related compounds as p2y1 receptor inhibitors for the treatment of thromboembolic disorders
KR20060087386A (ko) 2005-01-28 2006-08-02 주식회사 대웅제약 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물
DE602006020871D1 (de) 2005-06-27 2011-05-05 Bristol Myers Squibb Co Lineare harnstoffmimetika-antagonisten des p2y1-rezeptors zur behandlung von thromboseleiden
WO2007002634A1 (en) * 2005-06-27 2007-01-04 Bristol-Myers Squibb Company Carbocycle and heterocycle antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
EP1899299B1 (en) 2005-06-27 2010-10-20 Bristol-Myers Squibb Company C-linked cyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
AR056867A1 (es) 2005-06-27 2007-10-31 Bristol Myers Squibb Co Antagonistas heterociclicos n- enlazados del receptor de p2y1 utiles en el tratamiento de condiciones tromboticas. composiciones farmaceuticas.
CN101058561B (zh) * 2006-04-19 2011-01-26 苏州爱斯鹏药物研发有限责任公司 用于抑制蛋白激酶的二苯脲衍生物及其组合物和用途
TW200824687A (en) 2006-08-25 2008-06-16 Abbott Lab Compounds that inhibit TRPV1 and uses thereof
US7960569B2 (en) * 2006-10-17 2011-06-14 Bristol-Myers Squibb Company Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
WO2008079683A2 (en) * 2006-12-20 2008-07-03 Abbott Laboratories N- (5, 6, 7, 8-tetrahydronaphthalen-1-yl) urea derivatives and related compounds as trpv1 vanilloid receptor antagonists for the treatment of pain
JP5675343B2 (ja) * 2007-04-18 2015-02-25 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としての尿素誘導体
WO2009035951A2 (en) * 2007-09-11 2009-03-19 Arete Therapeutics, Inc. Soluble epoxide hydrolase inhibitors
EP2323989A4 (en) 2008-03-20 2011-06-22 Abbott Lab METHODS FOR PREPARING AGENTS FOR THE CENTRAL NERVOUS SYSTEM THAT ARE TRPV1 ANTAGONISTS
EP2264031B1 (en) 2008-04-18 2015-04-15 Daewoong Pharmaceutical Co., Ltd. A novel benzoxazine benzimidazole derivative, a pharmaceutical composition comprising the same, and a use thereof
EP2377850A1 (en) * 2010-03-30 2011-10-19 Pharmeste S.r.l. TRPV1 vanilloid receptor antagonists with a bicyclic portion
KR101293384B1 (ko) 2010-10-13 2013-08-05 주식회사 대웅제약 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도
CN103159686A (zh) * 2011-12-09 2013-06-19 天津市国际生物医药联合研究院 一种hiv-1蛋白酶的脲类抑制剂
BR112014013178A2 (pt) * 2011-12-09 2017-06-13 Chiesi Farm Spa composto, composição farmacêutica e uso de um composto
US20230092163A1 (en) * 2019-06-14 2023-03-23 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
KR102334947B1 (ko) * 2020-04-22 2021-12-06 주식회사 제이맥켐 Trpv1 길항제로서 벤즈이미다졸론계 시남아마이드 유도체 및 이를 유효성분으로 함유하는 통증의 치료 또는 예방용 약학적 조성물
CN111704714B (zh) * 2020-07-01 2023-08-04 浙江大学 一种苯并五元、六元环(硫)脲催化剂及其在开环聚合中的应用
TW202235073A (zh) 2021-01-08 2022-09-16 美商Ｉｆｍ Ｄｕｅ有限公司 用於治療與sting活性相關的病狀之化合物及組合物
DE102022104759A1 (de) 2022-02-28 2023-08-31 SCi Kontor GmbH Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen
CN114805236B (zh) * 2022-06-06 2024-02-23 苏州大学 一种苯并恶唑衍生物及其制备方法和应用
CZ202322A3 (cs) * 2023-01-22 2024-07-31 Univerzita Hradec Králové Heterocyklická sloučenina pro inhibici růstu maligních tumorů

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US3711610A (en) * 1971-06-01 1973-01-16 Sterling Drug Inc Anticoccidiosis method and compositions involving indazolylphenylureas and indazolylphenylthioureas
US6093742A (en) * 1997-06-27 2000-07-25 Vertex Pharmaceuticals, Inc. Inhibitors of p38
US6294694B1 (en) * 1999-06-04 2001-09-25 Wisconsin Alumni Research Foundation Matrix metalloproteinase inhibitors and method of using same
US7217722B2 (en) * 2000-02-01 2007-05-15 Kirin Beer Kabushiki Kaisha Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
EP1268484A1 (en) * 2000-03-17 2003-01-02 Novo Nordisk A/S Condensed imidazoles as histamine h3 receptor ligands
AU2001280229B2 (en) * 2000-08-21 2006-12-07 Pacific Corporation Novel thiourea derivatives and the pharmaceutical compositions containing the same
GB0110901D0 (en) * 2001-05-02 2001-06-27 Smithkline Beecham Plc Novel Compounds

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