JP2005511087A5 - - Google Patents
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- Publication number
- JP2005511087A5 JP2005511087A5 JP2003551296A JP2003551296A JP2005511087A5 JP 2005511087 A5 JP2005511087 A5 JP 2005511087A5 JP 2003551296 A JP2003551296 A JP 2003551296A JP 2003551296 A JP2003551296 A JP 2003551296A JP 2005511087 A5 JP2005511087 A5 JP 2005511087A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- virus
- sgt
- preparation
- biomass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 23
- 238000002360 preparation method Methods 0.000 claims 13
- 241000700605 Viruses Species 0.000 claims 12
- 101000759013 Streptomyces griseus Trypsin Proteins 0.000 claims 11
- 239000002028 Biomass Substances 0.000 claims 8
- 239000003480 eluent Substances 0.000 claims 8
- 244000007835 Cyamopsis tetragonoloba Species 0.000 claims 5
- 239000004475 Arginine Substances 0.000 claims 4
- 150000001409 amidines Chemical class 0.000 claims 4
- 150000001412 amines Chemical class 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 4
- 238000004113 cell culture Methods 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 241000894007 species Species 0.000 claims 4
- 108010059712 Pronase Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 230000003612 virological effect Effects 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 2
- 241000712464 Orthomyxoviridae Species 0.000 claims 1
- 241000711504 Paramyxoviridae Species 0.000 claims 1
- 108091005804 Peptidases Proteins 0.000 claims 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
- 241000187392 Streptomyces griseus Species 0.000 claims 1
- 108090000631 Trypsin Proteins 0.000 claims 1
- 102000004142 Trypsin Human genes 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 claims 1
- 230000003796 beauty Effects 0.000 claims 1
- PXXJHWLDUBFPOL-UHFFFAOYSA-N benzamidine Chemical group NC(=N)C1=CC=CC=C1 PXXJHWLDUBFPOL-UHFFFAOYSA-N 0.000 claims 1
- 230000031018 biological processes and functions Effects 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 229910017053 inorganic salt Inorganic materials 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 239000012679 serum free medium Substances 0.000 claims 1
- 239000012588 trypsin Substances 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/006,223 US6830917B2 (en) | 2001-12-10 | 2001-12-10 | Method of isolation and purification of trypsin from pronase protease and use thereof |
| PCT/EP2002/014005 WO2003050275A2 (en) | 2001-12-10 | 2002-12-10 | Method of isolation and purification of trypsin from pronase and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010146898A Division JP2010268799A (ja) | 2001-12-10 | 2010-06-28 | プロナーゼからのトリプシンの単離および精製の方法ならびにそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005511087A JP2005511087A (ja) | 2005-04-28 |
| JP2005511087A5 true JP2005511087A5 (enExample) | 2006-01-12 |
| JP4629336B2 JP4629336B2 (ja) | 2011-02-09 |
Family
ID=21719866
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003551296A Expired - Fee Related JP4629336B2 (ja) | 2001-12-10 | 2002-12-10 | プロナーゼからのトリプシンの単離および精製の方法ならびにそれらの使用 |
| JP2010146898A Withdrawn JP2010268799A (ja) | 2001-12-10 | 2010-06-28 | プロナーゼからのトリプシンの単離および精製の方法ならびにそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010146898A Withdrawn JP2010268799A (ja) | 2001-12-10 | 2010-06-28 | プロナーゼからのトリプシンの単離および精製の方法ならびにそれらの使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US6830917B2 (enExample) |
| EP (1) | EP1456228B1 (enExample) |
| JP (2) | JP4629336B2 (enExample) |
| CN (2) | CN101348780B (enExample) |
| AT (1) | ATE508137T1 (enExample) |
| AU (2) | AU2002363865B2 (enExample) |
| CA (1) | CA2469484C (enExample) |
| DE (1) | DE60239957D1 (enExample) |
| DK (1) | DK1456228T3 (enExample) |
| MX (1) | MXPA04005639A (enExample) |
| NO (1) | NO335427B1 (enExample) |
| WO (1) | WO2003050275A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100687884B1 (ko) | 2005-12-30 | 2007-02-27 | 한국과학기술원 | 스트렙토마이시스 그리세우스 유래의 조절유전자 ｓｇｔＲ1및 ｓｇｔＲ2를 이용한 재조합 트립신의 대량 생산방법 |
| JP6021218B2 (ja) * | 2012-06-25 | 2016-11-09 | 多木化学株式会社 | コラーゲン誘導体の製造方法 |
| UA120259C2 (uk) | 2013-11-08 | 2019-11-11 | Пресіжн Плентінг Елелсі | Система керування вагою сільськогосподарського знаряддя |
| CN108333358B (zh) * | 2017-01-19 | 2020-05-01 | 深圳市新产业生物医学工程股份有限公司 | 一种免疫亲和纯化洗脱液的筛选方法 |
| CN112143693B (zh) | 2019-06-28 | 2024-12-27 | 杭州康万达医药科技有限公司 | 一种生产病毒的方法及收获液组合物 |
| CN110343689B (zh) * | 2019-08-23 | 2021-11-05 | 四川大学 | 一种链霉菌胰蛋白酶gm2938及其在枯草芽孢杆菌中的异源表达 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE445466B (sv) * | 1977-12-01 | 1986-06-23 | Wellcome Found | Sett att foroka rotavirus in vitro |
| CA1122527A (en) * | 1979-05-15 | 1982-04-27 | Karen K. Brown | Influenza vaccine production in liquid cell culture |
| US4500513A (en) * | 1979-05-15 | 1985-02-19 | Miles Laboratories, Inc. | Influenza vaccine production in liquid cell culture |
| US4973554A (en) * | 1987-05-29 | 1990-11-27 | National Research Council Of Canada | Affinity process for trypsin purification and stabilization |
| JPH02268681A (ja) * | 1989-04-07 | 1990-11-02 | Green Cross Corp:The | ウロキナーゼ前駆体の安定化方法及び乾燥製剤 |
| RU2082431C1 (ru) * | 1993-05-12 | 1997-06-27 | Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им.Пастера | Способ получения инактивированной гриппозной вакцины |
| US5824536A (en) * | 1994-08-23 | 1998-10-20 | St. Jude Children's Research Hospital | Influenza virus replicated in mammalian cell culture and vaccine production |
| ES2323490T3 (es) | 1994-11-10 | 2009-07-17 | Baxter Healthcare Sa | Procedimiento de produccion de agentes biologicos en un medio de cultivo sin proteinas. |
| US5989805A (en) * | 1995-10-27 | 1999-11-23 | Board Of Trustees Operating Michigan State University | Immortal avian cell line to grow avian and animal viruses to produce vaccines |
| AT404597B (de) | 1995-11-24 | 1998-12-28 | Immuno Ag | Verfahren zur herstellung von proteinen |
| US5905042A (en) * | 1996-04-01 | 1999-05-18 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Cultured inner cell mass cell lines derived from bovine or porcine embryos |
| US6168944B1 (en) * | 1997-01-31 | 2001-01-02 | Schering Corporation | Methods for cultivating cells and propagating viruses |
| AT407255B (de) | 1997-06-20 | 2001-02-26 | Immuno Ag | Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons |
| ES2435141T3 (es) * | 1999-02-22 | 2013-12-18 | University Of Connecticut | Nuevas formulaciones de factor VIII libres de albúmina |
| US20030032146A1 (en) * | 2001-07-10 | 2003-02-13 | Dwulet Francis Edward | Enzyme/tag binding and detection system |
| US6825027B2 (en) * | 2001-12-10 | 2004-11-30 | Baxter Healthcare S.A. | Method of production of purified hepatitis a virus particles and vaccine preparation |
-
2001
- 2001-12-10 US US10/006,223 patent/US6830917B2/en not_active Expired - Lifetime
-
2002
- 2002-12-10 CN CN200810137978.7A patent/CN101348780B/zh not_active Expired - Fee Related
- 2002-12-10 CN CN02827638.8A patent/CN1617882B/zh not_active Expired - Fee Related
- 2002-12-10 WO PCT/EP2002/014005 patent/WO2003050275A2/en not_active Ceased
- 2002-12-10 DK DK02798324.6T patent/DK1456228T3/da active
- 2002-12-10 JP JP2003551296A patent/JP4629336B2/ja not_active Expired - Fee Related
- 2002-12-10 AT AT02798324T patent/ATE508137T1/de active
- 2002-12-10 CA CA2469484A patent/CA2469484C/en not_active Expired - Fee Related
- 2002-12-10 MX MXPA04005639A patent/MXPA04005639A/es active IP Right Grant
- 2002-12-10 AU AU2002363865A patent/AU2002363865B2/en not_active Ceased
- 2002-12-10 DE DE60239957T patent/DE60239957D1/de not_active Expired - Lifetime
- 2002-12-10 EP EP02798324A patent/EP1456228B1/en not_active Expired - Lifetime
-
2004
- 2004-07-09 NO NO20042908A patent/NO335427B1/no not_active IP Right Cessation
- 2004-09-17 US US10/944,218 patent/US7223595B2/en not_active Expired - Fee Related
-
2007
- 2007-04-20 US US11/788,714 patent/US7659380B2/en not_active Expired - Fee Related
-
2008
- 2008-10-02 AU AU2008229752A patent/AU2008229752B2/en not_active Ceased
-
2009
- 2009-12-28 US US12/648,170 patent/US8389261B2/en not_active Expired - Fee Related
-
2010
- 2010-06-28 JP JP2010146898A patent/JP2010268799A/ja not_active Withdrawn
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